Hydrothermal fractionation of woody biomass: lignin effect over sugars recovery

Producción CientíficaSubcritical water was employed to fractionate woody biomass into carbohydrates and lignin. Nine urban trees species (hardwood and softwood) from Spain were studied. The experiments were carried out in a semi-continuous reactor at 250 °C for 64 min. The hemicellulose and cellulose recovery yields were between 30% wt. and 80% wt. while the lignin content in the solid product ranged between 32% wt. and 92% wt. It was observed that an increment of solubilized lignin disfavored the hydrolysis of hemicelluloses. It was determined that the maximum extraction of hemicellulose was achieved at 20 min of solid reaction time while the extraction of celluloses not exhibited a maximum value. The hydrolysis of hemicellulose and cellulose would be governed by the hydrolysis kinetic and the polymers accessibility. In addition, the extraction of hemicellulose was negatively affected by the lignin content in the raw material while cellulose hydrolysis was not affected by this parameter.FEDER and Spanish Economy and Competitiveness Ministry (former Science and Innovation Ministry) Project Reference: CTQ2011-27347, ENE2012-33613 (FracBioFuel), CTQ2013-44143-R and Junta de Castilla y León Project Reference: VA254B11-2 for fundin

Gender equality in STEM programs: a proposal to analyse the situation of a university about the gender gap

[EN]According to the Global Gender Gap Report 2020, most of the countries have achieved gender parity in educational attainment. Furthermore, Latin America and Europe have more women than men enrolled in tertiary education. The problem arises when those numbers are analysed by degree studies. There is a gender gap in science, technology, engineering and mathematics (STEM), with a low number of women enrolled in those programs and even lower numbers of graduates. The universities have a key role to steer new conceptions and understanding of the females in STEM . The higher education institutions have to define measures and policies to reduce the gender gap in the careers of the future. This work aims to provide a proposal to analyse the gender equality gap in STEM as a first step to define gender equality action plans focused on processes of attraction, access and retention and guidance in STEM programs. The proposal was applied in ten Latin American universities from Chile, Colombia, Costa Rica, Ecuador and Mexico, and five European universities from Finland, Ireland, Italy, Spain, United Kingdom

Adaptación y validación de un cuestionario para medir la percepción de la calidad percibida por los usuarios externos de los campos de golf: Andalucía (España)

The objective of this work is to translate, adapt and validate the Customer Service Survey Quality Golf Course (CSQSGC). This tool is the most complete in the literature, and it is the best questionnaire to assess the perceived quality of the users. of the golf courses of Andalusia (Spain). In addition, its psychometric properties are examined: reliability and concurrent validity. There was a professional translation into Spanish of each item, content adaptation, evaluation of compression of the instrument through pilot testing, analysis of reliability with Cronbach’s alpha coefficient and validity, with an exploratory factor analysis, a confirmatory factor analysis of the instrument. Eleven expert judges participated in the process of adaptation and validation. Test-retest reliability methods were applied to a sample of 50 participants with an interval over a week. Subsequently, the questionnaire is applied to 200 users of golf courses. The adapted and validated instrument Analysis of Perceived Quality of the Game of Golf (CAPG) may be used to evaluate the quality of the golf courses based on the feedback of the users.It has a structure of 39 items (four more items added from the original version) divided into four subscales, matching with the original version, and it shows positive results for reliability and validity in the Spanish version. It is a useful tool for managers, because it allows the detection of deficiencies and areas for improvement for golf courses.El objetivo de este trabajo es traducir, adaptar y validar el cuestionario “Customer service quality survey golf course” (CSQSGC). Esta herramienta es la más completa en la literatura y es el mejor cuestionario para evaluar el grado de calidad percibida de los usuarios de los campos de golf de Andalucía (España). Se realizó una traducción profesional al español de cada ítem, adaptación de contenido, evaluación de compresión del instrumento mediante prueba piloto, análisis de confiabilidad con coeficiente alfa de Cronbach y validez, con análisis factorial exploratorio, análisis factorial confirmatorio del instrumento. Once jueces expertos participaron en el proceso de adaptación y validación. Se aplicaron métodos de confiabilidad test-retest a una muestra de 50 participantes con un intervalo de más de una semana. Posteriormente, se aplica el cuestionario a 200 usuarios de campos de golf. El instrumento adaptado y validado: Análisis de “Calidad percibida en el juego del golf” (CAPG) puede ser usado para evaluar la calidad de los campos de golf en función de la opinión de los usuarios. Tiene una estructura de 39 ítems (cuatro ítems más agregados de la versión original) divididos en 4 subescalas, coincidentes con la versión original, y muestra resultados favorables de fiabilidad y validez en su versión en español. Es una herramienta útil para los gestores, pues permite detectar deficiencias y las áreas de mejora de los campos de golf.Actividad Física y Deport

The underestimated role of carrion in vertebrates' diet studies

Aim: Despite the increasing scientific evidence on the importance of carrion in the ecology and evolution of many vertebrates, scavenging is still barely considered in diet studies. Here, we draw attention to how scientific literature has underestimated the role of vertebrates as scavengers, identifying the ecological traits that characterize those species whose role as scavengers could have gone especially unnoticed. Location: Global. Time Period: 1938–2022. Major Taxa Studied: Terrestrial vertebrate scavengers. Methods: We analysed and compared (a) the largest database available on scavenging patterns by carrion-consuming vertebrates, (b) 908 diet studies about 156 scavenger species and (c) one of the most complete databases on bird and mammal diets (Elton Traits database). For each of these 156 species, we calculated their scavenging degree (i.e. proportion of carcases where the species is detected consuming carrion) as a proxy for carrion consumption, and related their ecological traits with the probability of being identified as scavengers in diet studies and in the Elton Traits database. Results: More than half of the species identified as scavengers at monitored carcasses were not assigned carrion as food source in their diet studies nor in the Elton Traits database. Using a subset of study sites, we found a direct relationship between a species' scavenging degree and its rate of carrion biomass removal. In addition, scavenger species, which were classified as non-predators and mammals had a lower probability of being identified as scavengers in diet studies and in the Elton Traits database, respectively. Main Conclusions: Our results clearly indicate an underestimation of the role of scavenging in vertebrate food webs. Given that detritus recycling is fundamental to ecosystem functioning, we encourage further recognition and investigation of the role of carrion as a food resource for vertebrates, especially for non-predator species and mammals with higher scavenging degree.JM was supported by a Basque Government predoctoral grant (PRE_2018_2_0112), ZMR, LNA and EA by contracts co-funded by the Generalitat Valenciana and the European Social Fund (ESF) (APOSTD/2019/016, ACIF/2019/056 and APOSTD/2021/028 respectively). MM, JMPG and ESG were funded by MCIN/AEI/10.13039/501100011033, by ‘European Union NextGenerationEU/PRTR’, ERDF ‘A way of making Europe’ and by ESF ‘Investing in your future’ (grant numbers RYC-2015-19231, IJC-2019-038968, TED2021-130890B-C21, PID2021-128952NB-I00 and RYC-2019-027216-I). ESG was also partially funded by the HORIZONMSCA-2021-SE-0 action number: 101086387, ‘REMARKABLE’ project. ZMR and DRG were also funded by the Junta de Andalucía (POSTDOC_21_00353 and PREDOC_00262). RPR was co-funded by the ESF and Plan Propio I+D+i UCLM

A new vertebrate assemblage from the matute formation of the Cameros Basin (Ágreda, Spain): implications for the diversity during the jurassic/cretaceous boundary

Altres ajuts: Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature.The Ribota site (Ágreda, Soria, Spain) is a new locality in the Matute Formation (Tithonian-Berriasian) composed of several carbonate layers, outstandingly rich in macrovertebrate remains. Fossils show an unusual replacement of the original bioapatite by quartz, and are found as positive reliefs protruding from lacustrine limestone beds. This type of conservation has allowed the identification of around one hundred vertebrate bone accumulations in an outcrop of more than 10 hectares. Osteichthyans (articulated partial skeletons, cranial material, and isolated postcranial bones and scales), crocodylomorphs (disarticulated cranial material, isolated teeth, vertebrae and osteoderms), turtles (partial carapaces and plastra, but also isolated plates) and pterosaurs (cranial and appendicular elements) have been identified. Around 80 specimens have been collected and a preliminary study of part of the collection (35 specimens) has allowed the identification of at least 5 different taxa: Halecomorphi indet., Neoginglymodi indet., Goniopholididae indet., Testudinata indet., and Pterodactyloidea indet. This new site represents one of the few sites from this time interval preserved in a fully lacustrine environment, so these vertebrate assemblages are unique and composed of different animals that presumably lived around and within the lake. They are dominated by aquatic and amphibian vertebrates and was formed by attrition in this lacustrine environment, possibly far from the lake shoreline. These macrovertebrate assemblages provide new data about the diversity in the faunal ecosystems from the Jurassic/Cretaceous transition of the Iberian Basin Rift System

Effects of the Menstrual Cycle on Jumping, Sprinting and Force-Velocity Profiling in Resistance-Trained Women: A Preliminary Study

The aim of this study was to examine the effects of the menstrual cycle on vertical jumping, sprint performance and force-velocity profiling in resistance-trained women. A group of resistancetrained eumenorrheic women (n = 9) were tested in three phases over the menstrual cycle: bleeding phase, follicular phase, and luteal phase (i.e., days 1–3, 7–10, and 19–21 of the cycle, respectively). Each testing phase consisted of a battery of jumping tests (i.e., squat jump [SJ], countermovement jump [CMJ], drop jump from a 30 cm box [DJ30], and the reactive strength index) and 30 m sprint running test. Two different applications for smartphone (My Jump 2 and My Sprint) were used to record the jumping and sprinting trials, respectively, at high speed (240 fps). The repeated measures ANOVA reported no significant differences (p ≥ 0.05, ES < 0.25) in CMJ, DJ30, reactive strength index and sprint times between the different phases of the menstrual cycle. A greater SJ height performance was observed during the follicular phase compared to the bleeding phase (p = 0.033, ES = −0.22). No differences (p ≥ 0.05, ES < 0.45) were found in the CMJ and sprint force-velocity profile over the different phases of the menstrual cycle. Vertical jump, sprint performance and the force-velocity profiling remain constant in trained women, regardless of the phase of the menstrual cycle.Pre-competitive Projects for Early Stage Researchers Programme from the University of Granada (ref: PPJIA2020.03

Prevalence of antinuclear antibodies in inflammatory bowel disease and seroconversion after biological therapy

Background: Estimates of detectable antinuclear antibodies (ANA) prevalence vary widely, from 6% in healthy populations to 50-80% in patients with autoimmune disease. However, there is a lack of evidence about the overall prevalence in inflammatory bowel disease (IBD) and ANA seroconversion after the beginning of biological therapy. Objectives: The aim of the study was to investigate the overall prevalence of ANA in IBD patients, their relationship with different treatments, clinical outcomes and the seroconversion rate of ANA in patients treated with biological therapy. Methods: Ambispective observational study including all consecutive IBD patients was carried out. Information about the presence of ANA, disease phenotype, duration, activity, complications, and past and current treatments were transversally collected. Retrospectively, in patients with detectable ANA, data regarding previous ANA detection and the diagnosis of lupus-like syndrome (LLS) was gathered. Results: A total of 879 IBD patients were included. We observed a detectable ANA prevalence of 13.6%. The presence of ANA was frequently associated with biological therapy (36/118) and decreased when immunomodulators were combined to this therapy (7/32). Of 78 patients with ANA prior to the beginning of biological therapy, a seroconversion rate of 28.8% was observed after a mean of 3.14 years. Only 1 patient suffered LLS. Conclusion: Our study showed a prevalence of detectable ANA higher than the expected in healthy population. The presence of ANA was lower when immunomodulator therapy is associated. The ANA seroconversion rate is relevant after the initiation of biological treatment nevertheless, the risk of LLS appeared to be marginal.Funding: The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The authors report funding support from the Spanish Instituto de Salud Carlos III Grant (FIS–PI18/01304) related to this article

Depressed excitability and ion currents linked to slow exocytotic fusion pore in chromaffin cells of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis

Altered synaptic transmission with excess glutamate release has been implicated in the loss of motoneurons occurring in amyotrophic lateral sclerosis (ALS). Hyperexcitability or hypoexcitability of motoneurons from mice carrying the ALS mutation SOD1G93A (mSOD1) has also been reported. Here we have investigated the excitability, the ion currents, and the kinetics of the exocytotic fusion pore in chromaffin cells from postnatal day 90 to postnatal day 130 mSOD1 mice, when motor deficits are already established. With respect to wild-type (WT), mSOD1 chromaffin cells had a decrease in the following parameters: 95% in spontaneous action potentials, 70% in nicotinic current for acetylcholine (ACh), 35% in Na+ current, 40% in Ca2+-dependent K+ current, and 53% in voltage-dependent K+ current. Ca2+ current was increased by 37%, but the ACh-evoked elevation of cytosolic Ca2+ was unchanged. Single exocytotic spike events triggered by ACh had the following differences (mSOD1 vs. WT): 36% lower rise rate, 60% higher decay time, 51% higher half-width, 13% lower amplitude, and 61% higher quantal size. The expression of the α3-subtype of nicotinic receptors and proteins of the exocytotic machinery was unchanged in the brain and adrenal medulla of mSOD1, with respect to WT mice. A slower fusion pore opening, expansion, and closure are likely linked to the pronounced reduction in cell excitability and in the ion currents driving action potentials in mSOD1, compared with WT chromaffin cells.This work was funded by: (1) SAF-2010-21795, MINECO; (2) SAF-2010-792 18837, MINECO; (3) CABICYC, UAM/Bioibérica; (4) Fundación Teófilo 793 Hernando, Madrid, Spai