Mechanisms of institutional continuity in neoliberal "success stories" : developmental regimes in Chile and Estonia

© 2015 by The American Society for Biochemistry and Molecular Biology, Inc. Several mycoplasmas, such as the emergent human pathogen Mycoplasma genitalium, developed a complex polar structure, known as the terminal organelle (TO), responsible for a new type of cellular motility, which is involved in a variety of cell functions: cell division, adherence to host cells, and virulence. The TO cytoskeleton is organized as a multisubunit dynamic motor, including three main ultrastructures: the terminal button, the electrodense core, and the wheel complex. Here, we describe the interaction between MG200 and MG491, two of the main components of the TO wheel complex that connects the TO with the cell body and the cell membrane. The interaction between MG200 and MG491 has a KD in the 80 nM range, as determined by surface plasmon resonance. The interface between the two partners was confined to the >enriched in aromatic and glycine residues> (EAGR) box of MG200, previously described as a protein-protein interaction domain, and to a 25-residue-long peptide from the C-terminal region of MG491 by surface plasmon resonance and NMR spectroscopy studies. An atomic description of the MG200 EAGR box binding surface was also provided by solution NMR. An M. genitalium mutant lacking the MG491 segment corresponding to the peptide reveals specific alterations in cell motility and cell morphology indicating that the MG200-MG491 interaction plays a key role in the stability and functioning of the TO.This work was supported by Ministerio de Ciencia e Innovacion Grants BFU2012-36827 (to I. F.) and BFU2010-22209-C02-01 (to E. Q.), a grant from the Centre de Referencia de R+D de Biotecnologia (Generalitat de Catalunya, Spain) (to E. Q.), and by FEDER funds through the Operational Competitiveness Programme-COMPETE and by Portuguese national funds through FCT-Fundação para a Ciência e a Tecnologia under Project FCOMP-01-0124-FEDER-027581 (EXPL/BBB-BQB/0546/2012) (to B. C.). The NMR characterization was conducted through the FP7 Access to Research Infrastructures (Bio-NMR Contract 261863) and by Instruct, which is part of the European Strategy Forum on Research Infrastructures (ESFRI) and supported by national member subscriptionsPeer Reviewe

A detailed look at the most obscured galactic nuclei in the mid-infrared

Context. Compact obscured nuclei (CONs) represent an extreme phase of galaxy evolution where rapid supermassive black hole growth and/or compact star-forming activity is completely obscured by gas and dust. Aims. We investigate the properties of CONs in the mid-infrared and explore techniques aimed at identifying these objects, such as through the equivalent width (EW) ratios of their polycyclic aromatic hydrocarbon (PAH) features. Methods. We modelled Spitzer spectra by decomposing the continua into nuclear and star-forming components, from which we then measured the nuclear optical depth, τN, of the 9.8 μm silicate absorption feature. We also used Spitzer spectral maps to investigate how PAH EW ratios vary with aperture size for objects that host CONs. Results. We find that the nuclear optical depth, τN, strongly correlates with the HCN-vib emission line in the millimetre for CONs, with a Pearson correlation coefficient of 0.91. We find the PAH EW ratio technique to be effective at selecting CONs and robust against highly inclined galaxies, where strong dust lanes may mimic a CON-like spectrum by producing a high τN. Our analysis of the Spitzer spectral maps shows that the efficacy of the PAH EW ratios in isolating CONs is reduced when there is a strong starforming component from the host galaxy. In addition, we find that the use of the inferred nuclear optical depth is a reliable method for identifying CONs in 36+8-7% of ultra-luminous infrared galaxies and 17+3-3% of luminous infrared galaxies, consistent with previous work. Conclusions. We confirm mid-infrared spectra to be a powerful diagnostic of CONs. The increased sensitivity of JWST will allow the identification of CONs at cosmic noon, revealing this extreme but hidden phase of galaxy evolution

Ionize Hard: Interstellar PO+ Detection

We report the first detection of the phosphorus monoxide ion (PO+) in the interstellar medium. Our unbiased and very sensitive spectral survey toward the G+0.693–0.027 molecular cloud covers four different rotational transitions of this molecule, two of which (J = 1–0 and J = 2–1) appear free of contamination from other species. The fit performed, assuming local thermodynamic equilibrium conditions, yields a column density of N=(6.0 \ub1 0.7) 7 1011\ua0cm−2. The resulting molecular abundance with respect to molecular hydrogen is 4.5 7 10–12. The column density of PO+ normalized by the cosmic abundance of P is larger than those of NO+ and SO+, normalized by N and S, by factors of 3.6 and 2.3, respectively. The N(PO+)/N(PO) ratio is 0.12 \ub1 0.03, more than one order of magnitude higher than that of N(SO+)/N(SO) and N(NO+)/N(NO). These results indicate that P is more efficiently ionized than N and S in the ISM. We have performed new chemical models that confirm that the PO+ abundance is strongly enhanced in shocked regions with high values of cosmic-ray ionization rates (10–15 − 10–14 s−1), as occurring in the G+0.693–0.027 molecular cloud. The shocks sputter the interstellar icy grain mantles, releasing into the gas phase most of their P content, mainly in the form of PH3, which is converted into atomic P, and then ionized efficiently by cosmic rays, forming P+. Further reactions with O2 and OH produces PO+. The cosmic-ray ionization of PO might also contribute significantly, which would explain the high N(PO+)/N(PO) ratio observed. The relatively high gas-phase abundance of PO+ with respect to other P-bearing species stresses the relevance of this species in the interstellar chemistry of P

Unveiling Far-Infrared Counterparts of Bright Submillimeter Galaxies Using PACS Imaging

We present a search for Herschel-PACS counterparts of dust-obscured, high-redshift objects previously selected at submillimeter and millimeter wavelengths in the Great Observatories Origins Deep Survey North field. We detect 22 of 56 submillimeter galaxies (39%) with a SNR of >=3 at 100 micron down to 3.0 mJy, and/or at 160 micron down to 5.7 mJy. The fraction of SMGs seen at 160 micron is higher than that at 100 micron. About 50% of radio-identified SMGs are associated with PACS sources. We find a trend between the SCUBA/PACS flux ratio and redshift, suggesting that these flux ratios could be used as a coarse redshift indicator. PACS undetected submm/mm selected sources tend to lie at higher redshifts than the PACS detected ones. A total of 12 sources (21% of our SMG sample) remain unidentified and the fact that they are blank fields at Herschel-PACS and VLA 20 cm wavelength may imply higher redshifts for them than for the average SMG population (e.g., z>3-4). The Herschel-PACS imaging of these dust-obscured starbursts at high-redshifts suggests that their far-infrared spectral energy distributions have significantly different shapes than template libraries of local infrared galaxies.Comment: 6 pages, 4 figures. ApJ Letters in pres

Quasi-free (p,2p) reactions in inverse kinematics for studying the fission yield dependence on temperature

Despite the recent experimental and theoretical progress in the investigation of the nuclear fission process, a complete description still represents a challenge in nuclear physics because it is a very complex dynamical process, whose description involves the coupling between intrinsic and collective degrees of freedom, as well as different quantum-mechanical phenomena. To improve on the existing data on nuclear fission,we produce fission reactions of heavy nuclei in inverse kinematics by using quasi-free (p,2p) scattering, which induce fission through particle-hole excitations that can range from few to ten\u27s of MeV. The measurement of the four-momenta of the two outgoing protons allows to reconstruct the excitation energy of the fissioning nucleus and therefore to study the evolution of the fission yields with temperature. The realization of this kind of experiment requires a complex experimental setup, providing full isotopic identification of both fission fragments and an accurate measurement of the momenta of the two outgoing protons. This was realized recently at the GSI/FAIR facility and here some preliminary results are presented

The Next Generation of Axion Helioscopes: The International Axion Observatory (IAXO)

The International Axion Observatory (IAXO) is a proposed 4th-generation axion helioscope with the primary physics research goal to search for solar axions via their Primakoff conversion into photons of 1 \u2013 10 keV energies in a strong magnetic field. IAXO will achieve a sensitivity to the axion-photon coupling ga\u3b3 down to a few 710 1212 GeV 121 for a wide range of axion masses up to 3c 0.25 eV. This is an improvement over the currently best (3rd generation) axion helioscope, the CERN Axion Solar Telescope (CAST), of about 5 orders of magnitude in signal strength, corresponding to a factor 3c 20 in the axion photon coupling. IAXO's sensitivity relies on the construction of a large superconducting 8-coil toroidal magnet of 20 m length optimized for axion research. Each of the eight 60 cm diameter magnet bores is equipped with x-ray optics focusing the signal photons into 3c 0.2 cm2 spots that are imaged by very low background x-ray detectors. The magnet will be built into a structure with elevation and azimuth drives that will allow solar tracking for 12 hours each day. This contribution is a summary of our papers [1], [2] and [3] and we refer to these for further details

A Deeper Look at DES Dwarf Galaxy Candidates: Grus I and Indus II

We present deep g- and r-band Magellan/Megacam photometry of two dwarf galaxy candidates discovered in the Dark Energy Survey (DES), Grus I and Indus II (DES J2038-4609). For the case of Grus I, we resolved the main sequence turn-off (MSTO) and similar to 2 mags below it. The MSTO can be seen at g(0) similar to 24 with a photometric uncertainty of 0.03 mag. We show Grus I to be consistent with an old, metal-poor (similar to 13.3 Gyr, [Fe/H] similar to -1.9) dwarf galaxy. We derive updated distance and structural parameters for Grus I using this deep, uniform, wide-field data set. We find an azimuthally-averaged halflight radius more than two times larger (similar to 151(-31)(+21) pc; similar to 4'. 16(-0.74)(+0.54)) and an absolute V-band magnitude similar to-4.1 that is similar to 1 magnitude brighter than previous studies. We obtain updated distance, ellipticity, and centroid parameters that are in agreement with other studies within uncertainties. Although our photometry of Indus II is similar to 2-3 magnitudes deeper than the DES Y1 public release, we find no coherent stellar population at its reported location. The original detection was located in an incomplete region of sky in the DES Y2Q1 data set and was flagged due to potential blue horizontal branch member stars. The best-fit isochrone parameters are physically inconsistent with both dwarf galaxies and globular clusters. We conclude that Indus II is likely a false positive, flagged due to a chance alignment of stars along the line of sight

Weak lensing of Type Ia Supernovae from the Dark Energy Survey

We consider the effects of weak gravitational lensing on observations of 196 spectroscopically confirmed Type Ia Supernovae (SNe Ia) from years 1 to 3 of the Dark Energy Survey (DES). We simultaneously measure both the angular correlation function and the non-Gaussian skewness caused by weak lensing. This approach has the advantage of being insensitive to the intrinsic dispersion of SNe Ia magnitudes. We model the amplitude of both effects as a function of $\sigma_8$, and find $\sigma_8 = 1.2^{+0.9}_{-0.8}$. We also apply our method to a subsample of 488 SNe from the Joint Light-curve Analysis (JLA) (chosen to match the redshift range we use for this work), and find $\sigma_8 = 0.8^{+1.1}_{-0.7}$. The comparable uncertainty in $\sigma_8$ between DES-SN and the larger number of SNe from JLA highlights the benefits of homogeneity of the DES-SN sample, and improvements in the calibration and data analysis.Comment: 10 pages, 7 figures, MNRA

Weak-lensing mass calibration of redMaPPer galaxy clusters in Dark Energy Survey Science Verification data

We use weak-lensing shear measurements to determine the mean mass of optically selected galaxy clusters in Dark Energy Survey Science Verification data. In a blinded analysis, we split the sample of more than 8000 redMaPPer clusters into 15 subsets, spanning ranges in the richness parameter 5 ≤ λ ≤ 180 and redshift 0.2 ≤ z ≤ 0.8, and fit the averaged mass density contrast profiles with a model that accounts for seven distinct sources of systematic uncertainty: shear measurement and photometric redshift errors; clustermember contamination; miscentring; deviations from the NFW halo profile; halo triaxiality and line-of-sight projections. We combine the inferred cluster masses to estimate the joint scaling relation between mass, richness and redshift, M(λ, z) ∝ M0λF (1 + z) G. We find M0 ≡ (M200m | λ = 30, z = 0.5) = [2.35 ± 0.22 (stat) ± 0.12 (sys)] × 1014 M., with F = 1.12 ± 0.20 (stat) ± 0.06 (sys) and G = 0.18 ± 0.75 (stat) ± 0.24 (sys). The amplitude of the mass–richness relation is in excellent agreement with the weak-lensing calibration of redMaPPer clusters in SDSS by Simet et al. and with the Saro et al. calibration based on abundance matching of SPT-detected clusters. Our results extend the redshift range over which the mass–richness relation of redMaPPer clusters has been calibrated with weak lensing from z ≤ 0.3 to z ≤ 0.8. Calibration uncertainties of shear measurements and photometric redshift estimates dominate our systematic error budget and require substantial improvements for forthcoming studies

Quantum numbers of the X(3872)X(3872) state and orbital angular momentum in its ρ0Jψ\rho^0 J\psi decay

Angular correlations in $B^+\to X(3872) K^+$ decays, with $X(3872)\to \rho^0 J/\psi$, $\rho^0\to\pi^+\pi^-$ and $J/\psi \to\mu^+\mu^-$, are used to measure orbital angular momentum contributions and to determine the $J^{PC}$ value of the $X(3872)$ meson. The data correspond to an integrated luminosity of 3.0 fb$^{-1}$ of proton-proton collisions collected with the LHCb detector. This determination, for the first time performed without assuming a value for the orbital angular momentum, confirms the quantum numbers to be $J^{PC}=1^{++}$. The $X(3872)$ is found to decay predominantly through S wave and an upper limit of $4\%$ at $95\%$ C.L. is set on the fraction of D wave.Comment: 16 pages, 4 figure