756 research outputs found

    Cwbr Author Interview: The Union War

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    Interview with Dr. Gary Gallagher, John L. Nau III Professor of History at the University of Virginia Interviewed by Nathan Buman Civil War Book Review (CWBR): Today, I\u27m delighted to be joined by Gary Gallagher who is John L. Nau III Professor of History at the University of Virginia to discuss his most recent book The Union War. Professor Gallagher, thank you for talking with us today. Gary Gallagher (GG): Thanks for inviting me

    Cold Harbor Syndrome: Balanced, Compelling Study\u27 Examines Grant\u27s Overland Miscalculations

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    Ulysses S. Grant\u27s offensive against Robert E. Lee\u27s entrenched Army of Northern Virginia at Cold Harbor on June 3, 1864, summons powerful images. Northern assaults that day stand alongside Ambrose E. Burnside\u27s attacks at Fredericksburg and John Bell Hood\u27s at Franklin as examples of seemingly poin...

    An Analysis of Milk Assembly Costs in the Greater Ohio Area: A Multi-Output Approach

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    A non-traditional multi-output cost function for milk haulers is estimated. Hauling firm outputs are (i) assembly miles, (ii) transport miles, and (iii) volume of milk hauled. Data were provided by 40 firms. The estimated cost function is shown to exhibit substantial economies of scale for all three joint outputs

    Crucible of the Civil War: Virginia from Secession to Commemoration

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    Crucible of the Civil War offers an illuminating portrait of the state’s wartime economic, political, and social institutions. Weighing in on contentious issues within established scholarship while also breaking ground in areas long neglected by scholars, the contributors examine such concerns as the war’s effect on slavery in the state, the wartime intersection of race and religion, and the development of Confederate social networks. They also shed light on topics long disputed by historians, such as Virginia’s decision to secede from the Union, the development of Confederate nationalism, and how Virginians chose to remember the war after its close.https://scholarship.richmond.edu/bookshelf/1258/thumbnail.jp

    Nerve conduction studies are safe in patients with central venous catheters

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    IntroductionIt is unknown if central venous catheters bypass the skin’s electrical resistance and engender a risk of nerve conduction study‐induced cardiac arrhythmia. The objective of this study is to determine if nerve conduction studies affect cardiac conduction and rhythm in patients with central venous catheters.MethodsUnder continuous 12‐lead electrocardiogram monitoring, subjects with and without central venous catheters underwent a series of upper extremity nerve conduction studies. A cardiologist reviewed the electrocardiogram tracings for evidence of cardiac conduction abnormality or arrhythmia.ResultsTen control subjects and 10 subjects with central venous catheters underwent the nerve conduction study protocol. No malignant arrhythmias or conduction abnormalities were noted in either group.ConclusionsNerve conduction studies of the upper extremities, including both proximal stimulation and repetitive stimulation, do not appear to confer increased risk of cardiac conduction abnormality in those patients with central venous catheters who are not critically ill or have a prior history of arrhythmia. Muscle Nerve 56: 321–323, 2017Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/137740/1/mus25497.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/137740/2/mus25497_am.pd

    Intercomparison of Multiple UV-LIF Spectrometers using the Aerosol Challenge Simulator

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    Measurements of primary biological aerosol particles (PBAPs) have been conducted worldwide using ultraviolet light-induced fluorescence (UV-LIF) spectrometers. However, how these instruments detect and respond to known biological and non-biological particles, and how they compare, remains uncertain due to limited laboratory intercomparisons. Using the Defence Science and Technology Laboratory, Aerosol Challenge Simulator (ACS), controlled concentrations of biological and non-biological aerosol particles, singly or as mixtures, were produced for testing and intercomparison of multiple versions of the Wideband Integrated Bioaerosol Spectrometer (WIBS) and Multiparameter Bioaerosol Spectrometer (MBS). Although the results suggest some challenges in discriminating biological particle types across different versions of the same UV-LIF instrument, a difference in fluorescence intensity between the non-biological and biological samples could be identified for most instruments. While lower concentrations of fluorescent particles were detected by the MBS, the MBS demonstrates the potential to discriminate between pollen and other biological particles. This study presents the first published technical summary and use of the ACS for instrument intercomparisons. Within this work a clear overview of the data pre-processing is also presented, and documentation of instrument version/model numbers is suggested to assess potential instrument variations between different versions of the same instrument. Further laboratory studies sampling different particle types are suggested before use in quantifying impact on ambient classification.Peer reviewe

    Differential Gene Expression in Liver, Gill, and Olfactory Rosettes of Coho Salmon (Oncorhynchus kisutch) After Acclimation to Salinity.

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    Most Pacific salmonids undergo smoltification and transition from freshwater to saltwater, making various adjustments in metabolism, catabolism, osmotic, and ion regulation. The molecular mechanisms underlying this transition are largely unknown. In the present study, we acclimated coho salmon (Oncorhynchus kisutch) to four different salinities and assessed gene expression through microarray analysis of gills, liver, and olfactory rosettes. Gills are involved in osmotic regulation, liver plays a role in energetics, and olfactory rosettes are involved in behavior. Between all salinity treatments, liver had the highest number of differentially expressed genes at 1616, gills had 1074, and olfactory rosettes had 924, using a 1.5-fold cutoff and a false discovery rate of 0.5. Higher responsiveness of liver to metabolic changes after salinity acclimation to provide energy for other osmoregulatory tissues such as the gills may explain the differences in number of differentially expressed genes. Differentially expressed genes were tissue- and salinity-dependent. There were no known genes differentially expressed that were common to all salinity treatments and all tissues. Gene ontology term analysis revealed biological processes, molecular functions, and cellular components that were significantly affected by salinity, a majority of which were tissue-dependent. For liver, oxygen binding and transport terms were highlighted. For gills, muscle, and cytoskeleton-related terms predominated and for olfactory rosettes, immune response-related genes were accentuated. Interaction networks were examined in combination with GO terms and determined similarities between tissues for potential osmosensors, signal transduction cascades, and transcription factors

    Ultraviolet observations of LMC nova 1988

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    The IUE obtained ultraviolet spectra of a nova in an external galaxy. The spectral features do not seem unusual for a nova at maximum but it is hoped to be able to follow it for a long enough time to be able to study the high ionization lines that appear when the density drops to lower values (the nebular stage). A high dispersion spectrum was also obtained to assist in the line identification and to study the line of sight to the LMC 1 deg of arc away from SN 1987A
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