113 research outputs found
Proportional Variation of Potential Groundwater Recharge as a Result of Climate Change and Land-Use: A Study Case in Mexico
Artículo en revista indexadaThis work proposes a methodology whereby the selection of hydrologic and land-use cover change (LUCC) models allows an assessment of the proportional variation in potential groundwater recharge (PGR) due to both land-use cover change (LUCC) and some climate change scenarios for 2050. The simulation of PGR was made through a distributed model, based on empirical methods and the forecasting of LUCC stemming from a supervised classification with remote sensing techniques, both inside a Geographic Information System. Once the supervised classification was made, a Markov-based model was developed to predict LUCC to 2050. The method was applied in Acapulco, an important tourism center for Mexico. From 1986 to 2017, the urban area increased 5%, and by 2050 was predicted to cover 16%. In this period, a loss of 7 million m3 of PGR was assumed to be caused by the estimated LUCC. From 2017 to 2050, this loss is expected to increase between 73 and 273 million m3 depending on the considered climate change scenario, which is the equivalent amount necessary for satisfying the water needs of 6 million inhabitants. Therefore, modeling the variation in groundwater recharge can be an important tool for identifying water vulnerability, through both climate and land-use change.CONACyT Centro de Ciencias de Desarrollo Regional (CCDR
Noviazgos violentos
En el marco de la Licenciatura de la carrera de Comunicación Social y Periodismo de la Universidad Nacional de La Plata, decidimos analizar la “Violencia en el Noviazgo”. En la provincia se tratan temáticas relacionadas con la sensibilización sobre la ley 26.485 de “Protección Integral para prevenir, sancionar y erradicar la violencia contra las mujeres en los ámbitos en que desarrollen sus relaciones interpersonales”, pero no orientado hacia el noviazgo. La violencia en el noviazgo es una problemática que siempre existió, pero nunca se trató con la relevancia que en verdad merece. Las estadísticas realizadas por la Secretaría de la Mujer de la Provincia de Formosa junto al Instituto del Género de la Universidad Nacional de Formosa, durante el periodo 2013/14 señala que de cada 10 personas 4 presentan denuncias relacionadas a problemas vinculares en la pareja.Facultad de Periodismo y Comunicación Socia
Eficacia de un programa para el tratamiento del sobrepeso y la obesidad no mórbida en atención primaria y su influencia en la modificación de estilos de vida
Introducción y Objetivos: la modificación de conductas
no saludables es fundamental para tratar la obesidad. El
objetivo de este estudio fue evaluar los efectos de un
programa basado en dieta, ejercicio y apoyo psicológico
en la modificación conductual de pacientes con sobrepeso
y obesidad tratados en Atención Primaria.
Métodos: 60 pacientes con sobrepeso grado II y
obesidad grado I-II fueron incluidos en este ensayo piloto.
Edad entre 18-50 años. Los pacientes recibieron un
programa que combinaba educación nutricional, actividad
física y apoyo psicológico. Formato grupal, periodicidad
quincenal. Los principales resultados medidos al
inicio y 6 meses fueron parámetros antropométricos
(índice de masa corporal, porcentaje de masa grasa, perímetro
cintura) y de estilos de vida usando el Cuestionario
para la valoración de hábitos de vida relacionados con el
sobrepeso y la obesidad. Consta de 5 dimensiones: contenido
calórico de la dieta (CC), alimentación saludable
(AS), ejercicio físico (EF), comer por bienestar psicológico
(BP) y consumo de alcohol (CA). La mayor puntuación
indica mejores hábitos para CC, AS y EF y peores
para BP y CA.
Resultados: al final de la intervención mejoraron las
escalas CC (2,60± 0,5 vs 3,49± 0,7, p<0,001), EF (2,19± 0,9
vs 3,17± 1,0, p<0,001) y AS (3,04± 0,4 vs 3,43± 0,4, p<0,05)
del cuestionario; CA (3,98± 0,7 vs. 4,25± 0,7, p<0,05) y BP
(2,82± 1,0 vs. 3,34± 0,7, p<0,001) empeoraron.
Conclusión: el programa basado en moderada restricción
de la dieta, aumento de actividad física y apoyo psicológico
puede mejorar parámetros antropométricos y
estilos de vida en pacientes obesos tratados en un centro
de Atención PrimariaBackground: Lifestyle intervention is fundamental for
obesity treatment. The aim of this study was to evaluate the
effects of a program focused on diet, exercise and psychological
support on Lifestyle Modification in overweight and
obese patients treated in Primary Health Care setting.
Methods: 60 patients with grade II overweight and
non-morbid grade I-II obesity were included in this pilot
clinical trial. Ages ranged from18 to 50 years. They were
provided with a program combining nutritional education,
physical activity and psychological support.
Subjects attended group sessions every 2 weeks. The main
outcome measures at baseline and 6 months were body
composition parameters (BMI, body fat percentage, waist
circumference) and lifestyle intervention using the Questionnaire
for the assessment of overweight and obesity
related lifestyles at baseline and six months. This questionnaire
yields an five dimensions: diet caloric intake
(CC), healthy eating (AS), physical activity (EF), searching
for psychological well-being eating (BP) and
alcohol intake (CA). The higher score indicates better
lifestyles for CC, AS, EF and worse for BP y CA.
Results: At the end of the intervention the program
achieved improvements in Questionnaire related
lifestyles subscales: CC (2,60± 0,5 vs. 3,49± 0,7, p<0,001),
EF (2,19± 0,9 vs. 3,17± 1,0, p<0,001) and AS (3,04± 0,4 vs.
3,43± 0,4, p<0,05); CA (3,98± 0,7 vs. 4,25± 0,7, p<0,05)
and BP (2,82± 1,0 vs. 3,34± 0,7, p<0,001) has got worse.
Conclusion: The Program focused on balanced and
moderate energy-restricted diets, increased physical activity
and psychological support may improve the anthropometric
parameters and the Lifestyle intervention in
obese patients treated in a primary healthcare center.Este proyecto ha sido becado por el Ministerio de
Ciencia e Innovación, a través del Instituto de Salud
Carlos III y la Subdirección General de Evaluación y
Fomento de la Investigación, en el marco del «Subprograma
de Proyectos de Investigación de Evaluación de
Tecnologías Sanitarias e Investigación en servicios de
salud». Convocatoria 2008 de ayudas de la Acción
Estratégica en Salud, en el marco del Plan Nacional de
I+D+I 2008-2011 (PI08/90357). Y por la Fundación
MAPFRE, a través del programa de Ayudas a la Investigación
(2009
On the Dissociation Pathways of Copper Complexes Relevant as Pet Imaging Agents
[Abstract] Several bifunctional chelators have been synthesized in the last years for the development of new 64Cu-based PET agents for in vivo imaging. When designing a metal-based PET probe, it is important to achieve high stability and kinetic inertness once the radioisotope is coordinated. Different competitive assays are commonly used to evaluate the possible dissociation mechanisms that may induce Cu(II) release in the body. Among them, acid-assisted dissociation tests or transchelation challenges employing EDTA or SOD are frequently used to evaluate both solution thermodynamics and the kinetic behavior of potential metal-based systems. Despite of this, the Cu(II)/Cu(I) bioreduction pathway that could be promoted by the presence of bioreductants still remains little explored. To fill this gap we present here a detailed spectroscopic study of the kinetic behavior of different macrocyclic Cu(II) complexes. The complexes investigated include the cross-bridge cyclam derivative [Cu(CB-TE1A)]+, whose structure was determined using single-crystal X-ray diffraction. The acid-assisted dissociation mechanism was investigated using HClO4 and HCl to analyse the effect of the counterion on the rate constants. The complexes were selected so that the effects of complex charge and coordination polyhedron could be assessed. Cyclic voltammetry experiments were conducted to investigate whether the reduction to Cu(I) falls within the window of common bioreducing agents. The most striking behavior concerns the [Cu(NO2Th)]2+ complex, a 1,4,7-triazacyclononane derivative containing two methylthiazolyl pendant arms. This complex is extremely inert with respect to dissociation following the acid-catalyzed mechanism, but dissociates rather quickly in the presence of a bioreductant like ascorbic acid.The authors thank Ministerio de Ciencia e Innovación (PID2019-104626GB-I00) and Xunta de Galicia (ED431B 2020/52) for generous financial support. R.U.-V. thanks Xunta de Galicia (Grant ED481A-2018/314) for funding her PhD contract. V. P. and R. T. acknowledge the Ministère de l'Enseignement Supérieur et de la Recherche and the Centre National de la Recherche Scientifique. L.V. thanks CACTI (Universidade de Vigo) for X-ray measurementsXunta de Galicia; ED431B 2020/52Xunta de Galicia; ED481A-2018/31
Predictor variables for low adherence to a lifestyle modification program of overweight treatment in primary health care
Objetivos: Identificar variables predictoras de baja
adherencia a un programa piloto de Modificación de
Estilos de Vida (MEV) para el tratamiento del exceso de
peso en Atención Primaria (AP).
Material y métodos: Se reclutaron 60 sujetos con IMC >
27 kg/m². Profesionales sanitarios dirigieron el programa,
en formato grupal y con una periodicidad quincenal,
basado en educación nutricional, pautas dietéticas individualizadas,
promoción de actividad física y apoyo motivacional.
Para identificar las variables relacionadas con la
adherencia al programa se utilizó un cuestionario validado
sobre Hábitos de Vida de personas con Sobrepeso y
Obesidad y se midieron variables antropométricas al inicio
y a los seis meses del tratamiento. Una baja adherencia al
programa fue considerada cuando los sujetos del estudio
acudían a menos del 80% de las visitas quincenales.
Resultados: Se adhirieron al programa 27 sujetos (45%).
Las variables asociadas a baja adherencia estuvieron relacionadas
al inicio del estudio con IMC ≥ 35 kg/m2 (p < 0,05);
período de exfumador ≤ 4 meses (p < 0,01); mayor contenido
calórico de la dieta (p < 0,01) y menor práctica de ejercicio
físico (p < 0,05). A los 6 meses los sujetos que finalizaron el
programa presentaron una disminución significativa de:
peso (86,0 ± 15,6 vs 79,2 ± 13,4 kg; p < 0,001);% de masa
grasa (41,6 ± 4,6 vs 38,8 ± 5,4%; p < 0,001) y glucemia (108
± 45,48 vs 94,38 ± 11,97 mg/dl; p < 0,01). Además mejoró el
perfil calórico de su dieta, disminuyendo sobretodo el
porcentaje de grasa sobre el valor calórico total (39,6 ± 4,8
vs. 35,5 ± 5,6%; p < 0,01).
Conclusión: Haber dejado de fumar recientemente,
padecer obesidad de grado dos o superior, el alto contenido
calórico de la dieta y la menor práctica de ejercicio
físico fueron las variables basales identificadas como
predictoras de una baja adherencia a un programa de
MEV para el tratamiento de sobrepeso y obesidad en AP.
Esta experiencia piloto una vez evaluada no la consideramos
satisfactoria y otras nuevas estrategias están en
fase de desarrolloObjectives: To identify predictive variables of low
adherence to a pilot Lifestyle Modification Program
(LMP) for overweight and obesity treatment in primary
health care (PC ).
Material and methods: Sixty subjects with BMI > 27
kg/m² were recruited. Health professionals directed the
program in a group structure and biweekly, based on
nutrition education with individualized dietary guidelines,
promotion of physical activity and motivational
support. A validated questionnaire on lifestyle habits for
overweight and obesity subjects was used to identify variables
related with program adherence and anthropometric
variables were measured before and 6 months
after intervention. Low adherence was considered when
patients attended to less than 80% of visits.
Results: Twenty-seven subjects (45%) presented high
adherence to the program. The variables associated to low
adherence were related to baseline with IMC ≥ 35 kg/m2 (p
< 0.05); ex smoker period ≤ 4 months (p < 0.01); high caloric
diet (p < 0.01) and scarce physical activity (p < 0.05). At 6
months the subjects who finalized the program presented a
significant decrease of weight (86.0 ± 15.6 vs 79.2 ± 13.4 kg;
p < 0,001); fat mass percentage (41,6 ± 4,6 vs 38.8 ± 5,4%; p
< 0.001), blood glucose (108 ± 45.48 vs 94.38 ± 11.97 mg/dl; p
< 0.01). It also improved caloric diet profile, above all
decreasing the percentage of fat (39.6 ± 4.8 vs 35.5 ±
5.6%; p < 0.01).
Conclusion: Have recently left smoking, obesity degree
two or higher, a high caloric diet and scarce physical
activity were basal variables identified as predictive of a
low adhesion to a LMP for the treatment of overweight
and obesity in primary health care. We do not consider
this pilot experience as satisfactory and other new strategies
are under developmentEste proyecto ha sido subvencionado a través del
“Subprograma de Proyectos de Investigación de
Evaluación de Tecnologías Sanitarias e Investigación
en servicios de salud” de la convocatoria 2008 de
ayudas de la Acción Estratégica en Salud, en el marco
del Plan Nacional de I+D+I 2008-201
Burnout in Nursing Managers: A Systematic Review and Meta-Analysis of Related Factors, Levels and Prevalence
This study forms part of the Doctoral Thesis of the first-named author within the Psychology
Doctoral Program from the University of Granada.Burnout syndrome is a major problem in occupational health, which also affects nursing
managers. The main aim was to analyze the level, prevalence and risk factors of burnout among
nursing managers. A systematic review with meta-analysis was conducted. The databases used
were Medline (Pubmed), PsycINFO, CINAHL, LILACS, Scielo and Scopus. The search equation
was “burnout AND nurs* AND (health manager OR case managers)”. Nursing managers present
high levels of emotional exhaustion and a high degree of depersonalization. Some studies show that
variables like age, gender, marital status, having children or mobbing and other occupational factors
are related with burnout. The prevalence estimation of emotional exhaustion with the meta-analysis
was high; 29% (95% CI = 9–56) with a sample of n = 780 nursing managers. The meta-analytical
estimation of the correlation between burnout and age was r = −0.07 (95% CI = −0.23–0.08). Work
overload, the need to mediate personnel conflicts, lack of time and support from superior staff,
contribute to the development of burnout among nursing managers.Junta de Andalucia
P11HUM-777
Prevalence, levels and related factors of burnout in nurse managers: A multi-centre cross-sectional study
Aims: The aims of this study are to analyse the prevalence and levels of burnout syndrome
in nurse managers and to evaluate the relationship between burnout and
related sociodemographic, occupational and psychological factors.
Background: Burnout syndrome, defined as an emotional response to chronic stress,
is a major problem among nurse managers.
Methods: The study was conducted using a cross-sectional survey design and data
collected by the Maslach Burnout Inventory, the revised NEO Five Factor Inventory
and the Educational-Clinical Questionnaire for Anxiety and Depression. The sample
population consisted of 86 nurse managers from different hospitals from the Public
Health Service of Andalusia, Spain.
Results: A total of 22.4% of the participants presented high levels of emotional
exhaustion, 21% experienced depersonalisation and 57.6% had little sense of personal
accomplishment. Working long shifts was related to burnout. Emotional
exhaustion and depersonalization were predicted by depression, while personal
accomplishment was predicted by conscientiousness, agreeableness and openness.
Conclusions: A total of 34.1% of the participants presented high levels of burnout,
manifested by feelings of low personal accomplishment. Psychological and occupational
factors play an important role in the development of this syndrome.
Implications for Nursing Management: Nurse managers should seek to detect burnout
among staff and colleagues matching the risk profile for this condition and promote
interventions to prevent it
Risk adapted high-dose and dose-dense therapies modulate the impact of biological classification in diffuse large B-cell lymphoma prognosis
Preservation of anti-SARS-CoV-2 neutralising antibodies in convalescent plasma after pathogen reduction with methylene blue and visible light
Background - COVID-19 convalescent plasma (CCP) is an experimental
treatment against SARS-CoV-2. Although there has so far been no evidence
of transmission through transfusion, pathogen reduction technologies (PRT)
have been applied to CCP to mitigate risk of infectious disease. This study
aims to assess the impact of methylene blue (MB) plus visible light PRT on the
virus-neutralising activity of the specific antibodies against SARS-CoV-2.
Material and methods - Thirty-five plasma doses collected by plasmapheresis
from COVID-19 convalescent donors were subjected to MB plus visible light
PRT. Anti-SARS-CoV-2 RBD S1 epitope IgGs antibodies were quantified by
ELISA. Titres of SARS-CoV-2 neutralising antibodies (NtAbs) were measured
before and after the PRT process. A Spearman's correlation was run to
determine the relationship between antibody neutralisation ability and
SARS-CoV-2 IgG ELISA ratio. Pre- and post-inactivation neutralising antibody
titres were evaluated using a Wilcoxon test.
Results - The plasma pathogen reduction procedure did not diminish NtAbS
titres and so did not cause a change in the viral neutralisation capacity of
CCP. There was a strong correlation between pre-and post-PRT NtAbs and
anti-SARS-CoV-2 IgGs titres.
Discussion - Our results showed PRT with MB did not impair the CCP passive
immunity preserving its potential therapeutic potency. Therefore, PRT of CCP
should be recommended to mitigate the risk for transmission of transfusionassociated
infectious disease. There is a good correlation between SARS-CoV-2
IgG titres determined by ELISA and the neutralising capacity. This allows blood
centres to select CCP donors based on IgG ELISA titres avoiding the much
more labour-intensive laboratory processes for determining neutralising
antibodies.Peer reviewe
Trivial-to-Learn: Aprendizaje basado en juegos en el área de conocimiento de Farmacia y Tecnología Farmacéutica (TRIVIALFAR)
La sociedad actual demanda a las Instituciones Educativas profesionales que tengan una formación integral que les permita adaptarse al entorno y a los requerimientos sociolaborales. Para ello, es esencial el empleo de metodologías docentes activas, como el aprendizaje basado en juegos, donde el estudiante es el protagonista del proceso de enseñanza-aprendizaje. El objetivo principal de este proyecto es diseñar y desarrollar juegos tipo Trivial como estrategia de aprendizaje activo en las asignaturas del área de conocimiento de Farmacia y Tecnología Farmacéutica. Concretamente se han desarrollado dos tipos de actividades: juegos tipo Trivial virtuales en la asignatura de Biofarmacia y Farmacocinética, y juegos tipo Trivial presenciales en las asignaturas de Productos Sanitarios y Tecnología Farmacéutica I. Ambas actividades han resultado ser una excelente herramienta de autoevaluación y repaso de los contenidos impartidos en la asignatura. Los juegos desarrollados en modalidad presencial fueron mejor evaluados por los alumnos que los desarrollados en modalidad virtual. Además, estos juegos presenciales les permitía adquirir competencias transversales, principalmente habilidades comunicativas, de liderazgo y de trabajo colaborativo.Depto. de Farmacia Galénica y Tecnología AlimentariaFac. de FarmaciaFALSEsubmitte
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