Artículo en revista indexadaThis work proposes a methodology whereby the selection of hydrologic and land-use cover change (LUCC) models allows an assessment of the proportional variation in potential groundwater recharge (PGR) due to both land-use cover change (LUCC) and some climate change scenarios for 2050. The simulation of PGR was made through a distributed model, based on empirical methods and the forecasting of LUCC stemming from a supervised classification with remote sensing techniques, both inside a Geographic Information System. Once the supervised classification was made, a Markov-based model was developed to predict LUCC to 2050. The method was applied in Acapulco, an important tourism center for Mexico. From 1986 to 2017, the urban area increased 5%, and by 2050 was predicted to cover 16%. In this period, a loss of 7 million m3 of PGR was assumed to be caused by the estimated LUCC. From 2017 to 2050, this loss is expected to increase between 73 and 273 million m3 depending on the considered climate change scenario, which is the equivalent amount necessary for satisfying the water needs of 6 million inhabitants. Therefore, modeling the variation in groundwater recharge can be an important tool for identifying water vulnerability, through both climate and land-use change.CONACyT Centro de Ciencias de Desarrollo Regional (CCDR