ESTRATÉGIA E ADMINISTRAÇÃO PÚBLICA: O CASO DO PROGRAMA "CHOQUE DE GESTÃO" DO GOVERNO DO ESTADO DE MINAS GERAIS

Este trabalho objetiva analisar as possibilidades de construção de estratégias em organizações inseridas no setor público. Para tanto, apresenta-se a experiência do programa "Choque de Gestão", instituído pelo Governo do Estado de Minas Gerais. Verificou-se que o programa "Choque de Gestão" se constitui como inovadora experiência de inserção da administração estratégica no setor público, sobretudo ao permitir uma reorganização e modernização da Administração Pública. Isso remete a uma compreensão da administração estratégica como ponto de partida para a construção de possibilidades de gestão pública mais abrangentes, influindo nos resultados obtidos e nos objetivos alcançados e, em última análise, em uma perspectiva de desenvolvimento socioeconômico sustentável ao longo do tempo

Interpretable Ensembles of Classifiers for Uncertain Data with Bioinformatics Applications

Data uncertainty remains a challenging issue in many applications, but few classification algorithms can effectively cope with it. An ensemble approach for uncertain categorical features has recently been proposed, achieving promising results. It consists in biasing the sampling of features for each model in an ensemble so that less uncertain features are more likely to be sampled. Here we extend this idea of biased sampling and propose two new approaches: one for selecting training instances for each model in an ensemble and another for sampling features to be considered when splitting a node in a Random Forest training. We applied these approaches to classify ageing-related genes and predict drugs' side effects based on uncertain features representing protein-protein and protein-chemical interactions. We show that ensembles based on our proposed approaches achieve better predictive performance. In particular, our proposed approaches improved the performance of a Random Forest based on the most sophisticated approach for handling uncertain data in ensembles of this kind. Furthermore, we propose two new approaches for interpreting an ensemble of Naive Bayes classifiers and analyse their results on our datasets of ageing-related genes and drug's side effects

Caracterização em multiescala de carbonatos neoproterozóicos da Pedreira GMD, Formação Lagoa do Jacaré, Grupo Bambuí, Paraopeba-MG

O método Caracterização Multiescalar de Reservatórios (Camures) vem se consolidando como uma importante ferramenta e que tem auxiliado na caracterização dos mais diferentes tipos de afloramentos e seções de rochas sedimentares. O objetivo deste trabalho compreende a aplicação desse método em um afloramento da Formação Lagoa do Jacaré, Grupo Bambuí, representado por uma pedreira desativada na região de Paraopeba, centro-norte de Minas Gerais. Para tanto, utilizaram-se diferentes ferramentas investigativas em macro, meso e microescalas de análise para caracterização dessa unidade nesse afloramento. A caracterização litofaciológica de detalhe na pedreira revelou cinco litofácies carbonáticas principais. Dados geofísicos de Ground Penetrating Radar (GPR) e raios gama foram levantados para auxiliar no reconhecimento das principais geometrias e litologias presentes na área, bem como na correlação lateral dos perfis levantados na pedreira. A análise petrográfica microscópica mostra a ocorrência de seis fácies. A análise das litofácies e estruturas sedimentares presentes apontam para deposição sob influência de ondas de tempestade em diversos ciclos tempestíticos em plataforma carbonática rasa. Essa sequência é definida na base por brechas intraclásticas, representando momentos de alta energia, passando a momentos de menor energia que favorecem a deposição carbonática fina com estratificações hummocky e plano-paralelas, marcas onduladas associadas, até raros momentos de calmaria com deposição de sedimentos carbonáticos finos na transição antepraia-plataforma (shoreface-offshore).The Multiscale Reservoir Characterization (Caracterização Multiescalar de Reservatórios - CAMURES) method has been proving itself an important tool of geological investigation and helping in characterizing many types of outcrops and sedimentary successions. The objective of the present article is to apply this method in a limestone outcrop of Lagoa do Jacaré Formation, Bambuí Group, in a disabled quarry, in Paraopeba region, Minas Gerais State. For this purpose, different investigative tools were used, with different scales of observation, to best describe this geological unit. A detailed lithofaciological analysis was made, and five individual lithofacies were defined. Ground Penetrating Radar and gamma-ray data were acquired to complement the knowledge about geometry and lithotypes in the study area, and reveal information concerning the lateral correlation between the geological profiles described. Microscopic petrography revealed the presence of six microfacies associations. Analysis of lithofacies and structures points to deposition under the influence of storm waves in several storm cycles on shallow-marine carbonate platform. This sequence is defined by intraclastic breccias on the bottom, that represent high energy moments, passing to lower wave-influenced energy moments, which favour deposition of fine carbonates with hummocky and planar stratification, and also ripple marks, until rare moments of calm sea with deposition of fine carbonate in the shoreface-offshore transition

Effect of processing conditions on characteristics of dehydrated bee-pollen and correlation between quality parameters

The aim of the present study was to compare the physical, chemical and biological parameters and the microbiological quality of bee-pollen samples treated with different dehydration processes and to correlate the results. The samples came mainly from Eucalyptus (Myrtaceae) and Eupatorium (Asteraceae) plants. The dehydration conditions of the samples influenced the L*a*b* colour parameters and the biological value. Unlike the protein and lipid content, the glucose and fructose content were unaffected. The vitamin E content (27.2 ± 0.3 μg/g, 27.5 ± 0.4 μg/g) in oven-dehydrated samples with forced air circulation was significantly lower (P < 0.05) compared with lyophilized samples (37.5 ± 0.2 g/100 g, 53.7 ± 3.9 g/100 g). Overall, the results were inconclusive for vitamin B complex, minerals and microbiological indicators. There was a positive correlation between the colour parameters L* and b* and the total phenolic content, as well as between phenolic content and the antioxidant and antimicrobial capacity. The data indicate that lyophilization might be a viable alternative to the current process, resulting in dehydrated bee-pollen with higher biological activity.The authors are grateful to State of S~ao Paulo Research Foundation (FAPESP) for financial support (FAPESP process 2011/51741- 5) and scholarship granted to AAM De-Melo (FAPESP process 2011/ 11746-8 and FAPESP process 2013/23179-6). For a scholarship granted to OM Barth from the National Counsel of Technological and Scientific Development (CNPq, Process 304067/2013-0). To the MN Pr opolis company that supplied the samples.info:eu-repo/semantics/publishedVersio

Molecular Philogeography of Cacauhy (Theobroma speciosum) in the Brazilian Amazon/ Filogeografia molecular de cacauí (Theobroma speciosum) na Amazônia brasileira

This study aims to determine the phylogeographic patterns in natural populations of Theobroma speciosum through the analysis of cpDNA and ITS sequence polymorphisms. We sampled individuals of T. speciosum distributed in 13 populations in the Brazilian Amazon to obtain data of DNA sequences of the chloroplastidic and nuclear genomes. The DNAsp program was used to estimate the number of haplotypes, haplotypic diversity, nucleotide diversity, and number of polymorphic sites. The values of genetic diversity estimated for populations from cpDNA present low values of haplotype and nucleotide diversity. In contrast, for the nuclear region, high values of haplotype and nucleotide diversity were found (except for three populations). The phylogeographic analyses based on the chloroplastidic and nuclear genome of T. speciosum evidenced the existence of 07 haplotypes for the cpDNA and 36 for the ITS, denoting a haplotype sharing, which means that T. speciosum does not present a pronounced but a generalist phylogeographic structure

PP1- Índices de Helkimo e craniomandibular na classificação das disfunções temporomandibulares: estudo comparativo.

INTRODUÇÃO: As disfunções temporomandibulares apresentam sintomatologia variada e de várias intensidades. Assim, índices têm sido utilizados com o intuito de classificar os casos quanto à sua gravidade com base nos sinais e sintomas e exame padronizado

Parámetros físico-químicos y contenido de vitaminas del complejo B : un estudio exploratorio del polen apícola del sur de Brasil

This study aimed to determine the presence of B-complex vitamins and some physicochemical parameters in bee pollen samples from the southern Brazilian states of Paraná, Santa Catarina and Rio Grande do Sul and, then, to identify their correlations with the geographical and botanical origin of the samples using multivariate statistical techniques. B-complex vitamins were determined by HPLC and mean contents were 0.79 mg/100 g (vitamin B1 ), 0.88 mg/100 g (vitamin B2 ), 5.31 mg/100 g (sum of vitamin B3 vitamers) and 4.42 mg/100 g (sum of B6 vitamers). The physicochemical parameters of the samples were consistent with those reported in the literature. The results showed that bee pollen is an important source of B-complex vitamins and multivariate statistical exploratory techniques suggested its nutritional content should be evaluated locallyEl objetivo de este estudio fue determinar la presencia de vitaminas del complejo B y algunos parámetros físico-químicos en muestras de polen apícola oriundas de los Estados del Sur de Brasil (Paraná, Santa Catarina y Rio Grande do Sul); y correlacionar estos resultados con el origen botánico y geográfico, usando un análisis estadístico multivariado. Las vitaminas del complejo B fueron determinadas por HPLC y su contenido fue de 0,79 mg/100 g (vitamina B1 ); 0,88 mg/100 g (vitamina B2 ); 5,31 mg/100 g (suma de los compuestos de vitamina B3 ); y 4,42 mg/100 g (suma de los compuestos de vitamina B6 ). Los parámetros físico-químicos de las muestras fueron consistentes con los reportados en la literatura. Los resultados mostraron que el polen apícola fue una fuente importante de vitaminas del complejo B, y las técnicas multivariadas sugirieron que su contenido nutricional debe ser evaluado localmente

Tuberculosis Caused by Mycobacterium tuberculosis Complex in a Captive Tapir (Tapirus terrestris)

Background: Tuberculosis is an infectious disease caused by the Mycobacterium tuberculosis complex has already been identified in a great number of wild species. Captive animals may have a potential source for zoonoses, because is related to factors such as cohabitation, direct contact with the public, presence of biological vectors, nutritional deficiencies, absence of sanitary barriers, precautionary hygienic measures and sanitary vigilance. In Brazil, there is little information on tuberculosis in captivity animals, and little attention is given to the risks of disease transmission from humans. The aim of this study was to report the first diagnosed case of tuberculosis Tapirus terrestris in Brazilian Amazon region.Case: One Tapirus terrestris was kept by local zoobotanic foundation in city of Marabá, Southeast of Pará state, Brazilian Amazon, and became ill. Physical examination revealed cough, sneezing, nasal outflow, dyspnea, hyperthermia and lethargy, leading to death. Necropsy demonstrated severe pulmonary alterations: thickening of the inter-alveolar septa, alveolar emphysema, and miliary nodules with dimensions up to 5 mm, which were yellowish-white, caseous, and sometimes calcified. Additionally, large areas of caseous compaction of the parenchyma, characteristic of caseous tuberculosis. Histopathological analysis revealed a process characteristic of mycobacterial infection, with alveoli filled with caseous exudate and thickened septa and fibrocytes, in addition to recently formed tubercles, some with caseous necrosis, calcifications and Langhans cells. In the Ziehl-Neelsen staining, alcohol-acid resistant bacilli were observed in the mesenteric lymph nodes. No mycobacterial growth was observed in Lowenstein-Jensen culture medium. A nested PCR followed by a sequencing assay targeting the hsp65 gene and M. tuberculosis complex member was detected. Water and M. tuberculosis H37Rv were used as negative and positive controls, respectively.Discussion: This article reports the first case of tuberculosis in T. terrestris in Amazonia. The case of infection was caused by a complex of Mycobacterium tuberculosis, as well as reports of other studies described in wild animals. This record presented clinical and pathological similarity with the cases of a tapir and coati at the zoo of Curitiba, and non-human primates in bioteries in Belém. The disease was reported, also, in a T. indicus female in Bangkok, Thailand. In another study with two tapirs there was positivity of tuberculin test result in a Swedish zoo. In necropsy findings of tuberculosis in a Malayan tapir showed multiple white, caseous nodules spread throughout the lungs. Studies have shown that lesions can be in various organs, among them the mediastinal and mesenteric lymph nodes, liver, spleen, kidneys, ovaries, serosa, diaphragm, intestines and uterus. For exemple in a case of disseminated tuberculosis caused by M. tuberculosis in a Malayan tapir were described multiple granulomes, some coalescent, characterized by necrotic caseous centers, with some Langhans giant cells and a discrete fibrotic zone. In the present work, the results of the anatomopathological and molecular assays confirmed the clinical suspicion of respiratory infection and established the conclusive diagnosis of pulmonary tuberculosis caused by M. tuberculosis complex member. It is worth noting that tuberculosis is an important zoonotic disease affecting survival of the species, posing an extinction threat and also a public health concern

OS ESTUDOS SOBRE GOVERNANÇA NA HISTÓRIA DOS EVENTOS DA ANPAD

This research aims to present an analysis of the scientific production on the theme of governance in all its applications and without a temporal cut, presented in the meetings of the National Association of Graduate Studies and Research in Administration (ANPAD). Therefore, it was carried out a descriptive, quantitative, bibliometric research, which addresses Lotka's Law using the Lagrangian Poisson Model in 462 articles. The results showed an increasing trend in publications, the first article found dates from 1997, with 2019 being the year with the highest volume of articles, about 11% of the total. Regarding the scope of the theme, corporate governance is present in 54% of the articles. Among the 952 authors, 84,56% had only one participation as author and as for the most productive, are highlighted: Oliveira (10), Santos (9), Maçada (8) and Filho (8). As for the total productivity of the authors, adherence to the Lagrangian Poisson distribution model was confirmed. It is concluded that the studies on Governance are constantly advancing in their various areas of application, showing a great presence in the academy.&nbsp;Esta pesquisa tem por objetivo apresentar uma análise da produção científica sobre o tema governança em todas as suas aplicações e sem corte temporal, apresentados nos encontros da Associação Nacional de Pós-Graduação e Pesquisa em Administração (ANPAD). Para tanto, foi realizada uma pesquisa descritiva, quantitativa, bibliométrica, que aborda a Lei de Lotka utilizando-se o modelo Lagrangiano de Poisson em 462 artigos. Os resultados mostraram uma tendência crescente nas publicações, o primeiro artigo encontrado data de 1997, sendo 2019 o ano com maior volume de artigos, cerca de 11% do total. Em relação a abrangência do tema, governança corporativa está presente em 54% dos artigos. Dos 952 autores, 84,56% tiveram apenas uma participação em autoria e quanto aos mais produtivos, destacaram-se: Oliveira (10), Santos (9), Maçada (8) e Filho (8). Quanto à produtividade total dos autores, foi confirmada a aderência ao modelo de distribuição Lagrangiano de Poisson. Conclui-se que os estudos sobre Governança estão em constante avanço em suas diversas área de aplicação, demonstrando grande presença na academia

Ações de enfermagem na cardiopatia congênita

The aim was to analyze the nurses' coping in the treatment of congenital heart disease. This is an exploratory-descriptive literature study of qualitative origin, carried out in an electronic database of Latin American and Caribbean Literature in Health Sciences (LILACS), Database in Nursing (BDENF) and Scientific Electronic Library Online (SciELO) with a time frame of the last five years in Portuguese and English. A sample of 7 studies was obtained, all published in nursing journals, among the findings was the fundamental role of nursing action in the process of congenital heart disease. It is concluded that a newborn, admitted to an Intensive Care Unit, due to congenital heart disease, is predisposed to several other problems, causing some risks, requiring nursing care aimed at possible diagnoses that are affected.Objetivou-se analisar o enfrentamento do enfermeiro no tratamento da cardiopatia congênita. Trata-se de um estudo da literatura de caráter exploratório-descritivo e de origem qualitativa, realizada em banco de dados eletrônicos Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Banco de Dados em Enfermagem (BDENF) e Scientific Electronic Library Online (SciELO) com recorte temporal dos últimos cinco anos em português e inglês. Obteve-se uma amostra de 7 estudos, todos publicados em revistas de enfermagem, entre os achados foi notório o papel fundamental da ação da enfermagem no processo da cardiopatia congênita. Conclui-se que um recém-nascido, internado em uma Unidade de Terapia Intensiva, em decorrência de cardiopatia congênita, está predisposto a diversos outros problemas, acarretando alguns riscos, sendo necessário um cuidado de enfermagem voltado aos possíveis diagnósticos que são acometidos