La creatividad enjaulada en la traducción: una perspectiva neoinstitucional sobre la comunicación de crisis

Crisis communication research has primarily focused on universal models guiding managers of various organisations in times of crisis. Even though this is about to change, a tendency remains for research in the field to overlook the impact of structural conditions on organisation’s crisis communication. In order to add to the emergent discussion on new theoretical and empirical venues within the field of crisis communication, this paper proposes a framework based on new institutional theory for analysing crisis communication practices as a societal phenomenon. New institutionalism is advocated due to its ability to shift the focus from agency to structure and in doing so emphasise the social preconditions for organisational activities. In line with this, this conceptual paper discusses crisis communication as an institution, i.e., as a set of more or less conscious ideas about formats (the organisational structures developed for crisis communication work), contents (the content of organisations’ communication in times of crisis) and contexts (the situations during which organisations are expected to perform crisis communication). Moreover, we discuss how these ideas become translated (i.e., modified) as they travel (i.e., become legitimate, popular and get widely spread) across organisational and institutional contexts. In order to illustrate the framework described above, the Swedish authorities’ communication in connection to the A/H1N1 outbreak is used as a case study

Student and supervisor understanding of generic criteria for specific projects – A pilot study in an engineering education context

This paper offers an account of a pilot investigation into students’ and supervisors’ understanding and interpretation of university-wide guidelines and criteria for theses in engineering education. The university-wide criteria present both a means and a challenge for enhancing theses quality. To the extent that the means lies in indicating the expected standard, the challenge lies in the difficulty to interpret criteria relative specific student projects in order to decide what the criteria imply for specific engineering disciplines and projects. Consequently, there is a risk that despite articulating guidelines and criteria, the quality of theses does not improve since the discipline’s standards are insufficiently articulated by supervisors and poorly internalised by students. We suggest that revised supervision processes promoting student ownership and their informed engagement in criterion-based self- and peer-assessment might offer ways of promoting disciplinary discursive expertise for internalising standards by addressing the difficulty of understanding assessment criteria

Potential for waste reduction when planing wood

Abstract In Swedish sawmills, only half of the raw material becomes the planks and boards that is their main products. The rest turn into wood chips, saw dust and shavings. This study has investigated the potential to reduce waste simply by reducing the green target dimensions for the centre yield planks that are to be planed. It turned out that there are possibilities to reduce the green target thickness with 2.6 mm and the green target width with 3.8 mm for planks. The reduction would increase the volume yield with 0.5 % which roughly corresponds to 20,000 m 3 timber in Sweden per year

Communicating under the regimes of divergent ideas: how public agencies in Sweden manage tensions between transparency and consistency

In this article we draw on Scandinavian institutionalism to argue that ideas act as imperatives for organizations’ communication, whereby differences between ideas can generate tensions that organizations must manage. We focus on transparency and consistency, ideas that frequently underpin organizational communication, but are mobilized by different problems and offer different solutions. An analysis of communication policy and strategy documents in 188 Swedish public agencies shows how transparency and consistency coexist, but are translated into local settings in divergent ways. The resulting tensions relate to the purpose of communication, roles of organizational actors and of media, and stakeholder identities. Tensions are managed using three strategies: firewalling, ranking, and compromising. The findings show that ideas are fundamental to organizational communication, but that organizations also contribute to transformations and hybridizations of ideas. We suggest further analyses of interactions among institutions, organizations, and communication, particularly of how the translations of ideas generate tensions that must be resolved

Platelets stimulate fibroblast-mediated contraction of collagen gels

BACKGROUND: Platelets are thought to play a role in a variety of inflammatory conditions in the lung, some of which may lead to fibrosis. In the current study we tested the hypothesis that whole platelets and platelet lysate can mediate remodelling of extracellular matrix in vitro by affecting fibroblast-mediated contraction of a collagen gel. We also sought to determine to what extent platelet-derived growth factor (PDGF) and transforming growth factor-β (TGF-β) contribute to this effect. METHODS: Washed platelets, isolated from healthy blood donors, and platelet lysate (freezing and thawing), were cast together with human lung fibroblasts in three-dimensional collagen gels. The gels were then released and cultured for four days. PDGF and TGF-β(1 )concentrations were measured in culture supernatants by ELISA. RESULTS: Both platelets and platelet lysate augmented fibroblast-mediated gel contraction in a time and concentration dependent manner (19.9% ± 0.1 (mean ± SEM) of initial area vs. 48.0% ± 0.4 at 48 hours; P < 0.001 and 41.5% ± 0.6 vs. 60.6% ± 0.3 at 48 hours; P < 0.001, respectively). Fixed platelets had no effect in the system. Both TGF-β(1 )and PDGF-AA/AB were released in co-culture. PDGF-AA/AB had a maximum release at 24 hours whereas TGF-β(1 )release increased with longer culture periods. Neutralising antibodies to these mediators partially inhibited platelet-induced gel contraction. CONCLUSION: We conclude that platelets may promote remodelling of extracellular matrix in vitro and that PDGF and TGF-β partially mediate this effect, also indicating a role for other mediators. The findings may be an important mechanism in regulating repair processes after injury

Antibiotic resistance among major pathogens compared to hospital treatment guidelines and antibiotic use in Nordic hospitals 2010-2018

Background The Nordic countries have comparable nationwide antibiotic resistance surveillance systems and individual antibiotic stewardship programmes. The aim of this study was to assess antibiotic resistance among major pathogens in relation to practice guidelines for hospital antibiotic treatment and antibiotic use in Nordic countries 2010-2018. Methods Antibiotic resistance among invasive isolates from 2010-2018 and aggregated antibiotic use were obtained from the European Centre for Disease Prevention and Control. Hospital practice guidelines were obtained from national or regional guidelines. Results Antibiotic resistance levels among Escherichia coli and Klebsiella pneumoniae were similar in all Nordic countries in 2018 and low compared to the European mean. Guidelines for acute pyelonephritis varied; 2nd generation cephalosporin (Finland), 3rd generation cephalosporins (Sweden, Norway), ampicillin with an aminoglycoside or aminoglycoside monotherapy (Denmark, Iceland and Norway). Corresponding guidelines for sepsis of unknown origin were 2nd (Finland) or 3rd (Sweden, Norway, Iceland) generation cephalosporins, carbapenems, (Sweden) combinations of penicillin with an aminoglycoside (Norway, Denmark), or piperacillin-tazobactam (all Nordic countries). Methicillin-resistant Staphylococcus aureus rates were 0-2% and empirical treatment with anti-MRSA antibiotics was not recommended in any country. Rates of penicillin non-susceptibility among Streptococcus pneumoniae were low (Peer reviewe

Rapid Identification of Bio-Molecules Applied for Detection of Biosecurity Agents Using Rolling Circle Amplification

Detection and identification of pathogens in environmental samples for biosecurity applications are challenging due to the strict requirements on specificity, sensitivity and time. We have developed a concept for quick, specific and sensitive pathogen identification in environmental samples. Target identification is realized by padlock- and proximity probing, and reacted probes are amplified by RCA (rolling-circle amplification). The individual RCA products are labeled by fluorescence and enumerated by an instrument, developed for sensitive and rapid digital analysis. The concept is demonstrated by identification of simili biowarfare agents for bacteria (Escherichia coli and Pantoea agglomerans) and spores (Bacillus atrophaeus) released in field

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Liver biology and function, drug-induced liver injury (DILI) and liver diseases are difficult to study using current in vitro models such as primary human hepatocyte (PHH) monolayer cultures, as their rapid de-differentiation restricts their usefulness substantially. Thus, we have developed and extensively characterized an easily scalable 3D PHH spheroid system in chemically-defined, serum-free conditions. Using whole proteome analyses, we found that PHH spheroids cultured this way were similar to the liver in vivo and even retained their inter-individual variability. Furthermore, PHH spheroids remained phenotypically stable and retained morphology, viability, and hepatocyte-specific functions for culture periods of at least 5 weeks. We show that under chronic exposure, the sensitivity of the hepatocytes drastically increased and toxicity of a set of hepatotoxins was detected at clinically relevant concentrations. An interesting example was the chronic toxicity of fialuridine for which hepatotoxicity was mimicked after repeated-dosing in the PHH spheroid model, not possible to detect using previous in vitro systems. Additionally, we provide proof-of-principle that PHH spheroids can reflect liver pathologies such as cholestasis, steatosis and viral hepatitis. Combined, our results demonstrate that the PHH spheroid system presented here constitutes a versatile and promising in vitro system to study liver function, liver diseases, drug targets and long-term DILI