97 research outputs found

    Development of a Data Management Framework in Support of Southeastern Tidal Creek Research

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    2008 S.C. Water Resources Conference - Addressing Water Challenges Facing the State and Regio

    Genetic dissection of complete genomes of Type 2 PRRS viruses isolated in Denmark over a period of 15 years

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    AbstractType 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) was first detected in Europe in 1996 co-incident with the introduction of a live attenuated vaccine. Since then, only limited ORF5 and ORF7 sequences of Type 2 PRRS viruses have been reported throughout Europe. In the present study, the genetic and antigenic diversity of 11 complete genomes and 49 ORF5 and 55 ORF7 nucleotide sequences obtained from 57 viruses in Denmark from 2003 to 2012 were examined. The genetic identity of the 11 complete genomes to the vaccine strain (Ingelvac PRRS MLV) ranged between 93.6 and 99.6% while the 49 ORF5 sequences examined were 94.0–99.8% identical to the vaccine strain. Among the Danish sequences, the pairwise nucleotide identity was 90.9–100% and 93.0–100.0% for ORF5 and ORF7, respectively. Analysis of the genetic region encoding NSP2 revealed high diversity among the Danish viruses with an 86.6–98.9% range in similarity. Furthermore, several of the sequenced viruses harbored deletions in the NSP2 coding region. Phylogenetic analysis in a global Type 2 PRRSV framework classified all Danish isolates to a single cluster (sub-lineage 5.1) which comprised strains closely-related to the Type 2 prototype isolate VR2332

    25th annual computational neuroscience meeting: CNS-2016

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    The same neuron may play different functional roles in the neural circuits to which it belongs. For example, neurons in the Tritonia pedal ganglia may participate in variable phases of the swim motor rhythms [1]. While such neuronal functional variability is likely to play a major role the delivery of the functionality of neural systems, it is difficult to study it in most nervous systems. We work on the pyloric rhythm network of the crustacean stomatogastric ganglion (STG) [2]. Typically network models of the STG treat neurons of the same functional type as a single model neuron (e.g. PD neurons), assuming the same conductance parameters for these neurons and implying their synchronous firing [3, 4]. However, simultaneous recording of PD neurons shows differences between the timings of spikes of these neurons. This may indicate functional variability of these neurons. Here we modelled separately the two PD neurons of the STG in a multi-neuron model of the pyloric network. Our neuron models comply with known correlations between conductance parameters of ionic currents. Our results reproduce the experimental finding of increasing spike time distance between spikes originating from the two model PD neurons during their synchronised burst phase. The PD neuron with the larger calcium conductance generates its spikes before the other PD neuron. Larger potassium conductance values in the follower neuron imply longer delays between spikes, see Fig. 17.Neuromodulators change the conductance parameters of neurons and maintain the ratios of these parameters [5]. Our results show that such changes may shift the individual contribution of two PD neurons to the PD-phase of the pyloric rhythm altering their functionality within this rhythm. Our work paves the way towards an accessible experimental and computational framework for the analysis of the mechanisms and impact of functional variability of neurons within the neural circuits to which they belong

    Dunia Digital vs Dunia Rohani: Dilema Dalam Pertumbuhan Anak

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    Dalam era teknologi yang semakin maju termasuk gadget, telah menjadi bagian yang tak terpisahkan dari kehidupan manusia. Tidak bisa dipungkiri banyak waktu yang terbuang diakibatkan oleh penggunaan gadget di dalam kehidupan sehari-hari. Mulai dari anak kecil sampai orang dewasa terlibat dalam penggunaan gadget ini. Oleh karena itu, penelitian ini bertujuan untuk mencari tahu apa saja dampak penggunaan gadget terhadap kerohanian anak. Artikel ini menguraikan beberapa dampak positif dan negatif dalam penggunaan gadget terhadap pertumbuhan spiritual manusia. Penelitian ini menggunakan metode kualitatif dengan pendekatan kajian kepustakaan. Gadget memberikan manfaat yang signifikan dalam memfasilitasi komunikasi, memudahkan mengakses materi rohani, dan dapat mengatur jadwal dalam melangsungkan kegiatan-kegiatan rohani. Namun, penggunaan yang berlebihan atau tidak bijak dapat berdampak negatif seperti mengganggu kualitas dalam beribadah, menurunkan perhatian terhadap firman Tuhan dan merusak keseimbangan dalam kehidupan rohani. Orang tua memiliki peran pentin dalam mengawasi dan membimbing anak-anak dalam penggunaan gadget untuk memastikan pertumbuhan kerohanian mereka tidak terganggu. Kesimpulannya, penggunaan gadget ang bijak dan terkendali dapat memberikan manfaat bagi pertumbuhan kerohanian individu, begitu pula sebaliknya. Perlu kesadaran akan dampak negative yang mungkin timbul dan tindakan pencegahan yang diperlukan untuk mempertahankan keseimbangan antara teknologi da

    Stormwater Runoff - Modeling Impacts of Urbanization and Climate Change

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    2010 S.C. Water Resources Conference - Science and Policy Challenges for a Sustainable Futur

    Free-Spinning-Tunnel Investigation to Determine the Effect of Spin-Recovery Rockets and Thrust Simulation on the Recovery Characteristics of a 1/21-Scale Model of the Chance Vought F7U-3 Airplane, TED No. NACA AD 3103

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    An investigation of a l/21-scale model of the Chance Vought F7U-3 airplane in the co&at-load- condition has been conducted in the Langley 20-foot free-spinning tunnel, The recovery characteristics of the model were determined by use of spin-recovery rockets for the erect and inverted spinning condition. The rockets were so placed as to provide either a yawing or rolling moment about the model center of gravity. Also included in the investigation were tests to determine the effect of simulated engine thrust on the recovery characteristics of the model. On the basis of model tests, recoveries from erect and inverted spins were satisfactory when a yawing moment of 22,200 foot-pounds (full scale) was provided against the spin by rockets attached to the wing tips; the anti-spin yawing moment was applied for approximately 9 seconds, (full scale). Satisfactory recoveries were obtained from erect spins when a rolling moment of 22,200 foot-pounds (full scale) was provided with the spin (rolls right wing down in right spin). Although the inverted spin was satisfactorily terminated when a rolling moment of equal magnitude was provided, a roll rocket was not considered to be an optimum spin-recovery device to effect recoveries from inverted spins for this airplane because of resulting gyrations during spin recovery. Simulation of engine thrust had no apparent effect on the spin recovery characteristics
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