The genetic architecture of the human cerebral cortex

The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder

Child Abuse Pocket Atlas Series, Volume 3: Head Injuries

Of the injuries inflicted on physically abused children, head injuries are, in many cases, among the most damaging and potentially lethal. First responders and medical practitioners encountering children with head injuries may need to take quick and decisive measures to ensure a child s safety and, in the case of child death investigation, will need to recognize a variety of head injuries in order to identify or to rule out abusive trauma. This third volume of a new and ongoing series on child abuse provides professionals in medicine and law enforcement with more than 600 full-color photos and accompanying case studies representing a variety of both abusive and unintentional head injuries in children, as well as photographic studies of conditions mimicking abusive head trauma. Compact and comprehensive, this new title is certain to be an invaluable resource for any professionals investigating head injuries in children

Child Abuse Pocket Atlas Series, Volume 3: Head Injuries

Of the injuries inflicted on physically abused children, head injuries are, in many cases, among the most damaging and potentially lethal. First responders and medical practitioners encountering children with head injuries may need to take quick and decisive measures to ensure a child s safety and, in the case of child death investigation, will need to recognize a variety of head injuries in order to identify or to rule out abusive trauma. This third volume of a new and ongoing series on child abuse provides professionals in medicine and law enforcement with more than 600 full-color photos and accompanying case studies representing a variety of both abusive and unintentional head injuries in children, as well as photographic studies of conditions mimicking abusive head trauma. Compact and comprehensive, this new title is certain to be an invaluable resource for any professionals investigating head injuries in children.https://corescholar.libraries.wright.edu/books/1213/thumbnail.jp

Child Abuse Pocket Atlas Series Volume 3: Head Injuries

Of the injuries inflicted on physically abused children, head injuries are, in many cases, among the most damaging and potentially lethal. First responders and medical practitioners encountering children with head injuries may need to take quick and decisive measures to ensure a child’s safety and, in the case of child death investigation, will need to recognize a variety of head injuries in order to identify or to rule out abusive trauma. This third volume of a new and ongoing series on child abuse provides professionals in medicine and law enforcement with more than 600 full-color photos and accompanying case studies representing a variety of both abusive and unintentional head injuries in children, as well as photographic studies of conditions mimicking abusive head trauma. Compact and comprehensive, this new title is certain to be an invaluable resource for any professionals investigating head injuries in children

Child Abuse Pocket Atlas Series Volume 3: Head Injuries

Of the injuries inflicted on physically abused children, head injuries are, in many cases, among the most damaging and potentially lethal. First responders and medical practitioners encountering children with head injuries may need to take quick and decisive measures to ensure a child’s safety and, in the case of child death investigation, will need to recognize a variety of head injuries in order to identify or to rule out abusive trauma. This third volume of a new and ongoing series on child abuse provides professionals in medicine and law enforcement with more than 600 full-color photos and accompanying case studies representing a variety of both abusive and unintentional head injuries in children, as well as photographic studies of conditions mimicking abusive head trauma. Compact and comprehensive, this new title is certain to be an invaluable resource for any professionals investigating head injuries in children