Water Condensation Zones around Main Sequence Stars

Understanding the set of conditions that allow rocky planets to have liquid water on their surface -- in the form of lakes, seas or oceans -- is a major scientific step to determine the fraction of planets potentially suitable for the emergence and development of life as we know it on Earth. This effort is also necessary to define and refine the so-called "Habitable Zone" (HZ) in order to guide the search for exoplanets likely to harbor remotely detectable life forms. Until now, most numerical climate studies on this topic have focused on the conditions necessary to maintain oceans, but not to form them in the first place. Here we use the three-dimensional Generic Planetary Climate Model (PCM), historically known as the LMD Generic Global Climate Model (GCM), to simulate water-dominated planetary atmospheres around different types of Main-Sequence stars. The simulations are designed to reproduce the conditions of early ocean formation on rocky planets due to the condensation of the primordial water reservoir at the end of the magma ocean phase. We show that the incoming stellar radiation (ISR) required to form oceans by condensation is always drastically lower than that required to vaporize oceans. We introduce a Water Condensation Limit, which lies at significantly lower ISR than the inner edge of the HZ calculated with three-dimensional numerical climate simulations. This difference is due to a behavior change of water clouds, from low-altitude dayside convective clouds to high-altitude nightside stratospheric clouds. Finally, we calculated transit spectra, emission spectra and thermal phase curves of TRAPPIST-1b, c and d with H2O-rich atmospheres, and compared them to CO2 atmospheres and bare rock simulations. We show using these observables that JWST has the capability to probe steam atmospheres on low-mass planets, and could possibly test the existence of nightside water clouds.Comment: Accepted for publication in Astronomy & Astrophysic

Mesenchymal Stem Cell Therapy Regenerates the Native Bone-Tendon Junction after Surgical Repair in a Degenerative Rat Model

BACKGROUND: The enthesis, which attaches the tendon to the bone, naturally disappears with aging, thus limiting joint mobility. Surgery is frequently needed but the clinical outcome is often poor due to the decreased natural healing capacity of the elderly. This study explored the benefits of a treatment based on injecting chondrocyte and mesenchymal stem cells (MSC) in a new rat model of degenerative enthesis repair. METHODOLOGY: The Achilles' tendon was cut and the enthesis destroyed. The damage was repaired by classical surgery without cell injection (group G1, n = 52) and with chondrocyte (group G2, n = 51) or MSC injection (group G3, n = 39). The healing rate was determined macroscopically 15, 30 and 45 days later. The production and organization of a new enthesis was assessed by histological scoring of collagen II immunostaining, glycoaminoglycan production and the presence of columnar chondrocytes. The biomechanical load required to rupture the bone-tendon junction was determined. PRINCIPAL FINDINGS: The spontaneous healing rate in the G1 control group was 40%, close to those observed in humans. Cell injection significantly improved healing (69%, p = 0.0028 for G2 and p = 0.006 for G3) and the load-to-failure after 45 days (p<0.05) over controls. A new enthesis was clearly produced in cell-injected G2 and G3 rats, but not in the controls. Only the MSC-injected G3 rats had an organized enthesis with columnar chondrocytes as in a native enthesis 45 days after surgery. CONCLUSIONS: Cell therapy is an efficient procedure for reconstructing degenerative entheses. MSC treatment produced better organ regeneration than chondrocyte treatment. The morphological and biomechanical properties were similar to those of a native enthesis

The BioMart community portal: an innovative alternative to large, centralized data repositories.

The BioMart Community Portal (www.biomart.org) is a community-driven effort to provide a unified interface to biomedical databases that are distributed worldwide. The portal provides access to numerous database projects supported by 30 scientific organizations. It includes over 800 different biological datasets spanning genomics, proteomics, model organisms, cancer data, ontology information and more. All resources available through the portal are independently administered and funded by their host organizations. The BioMart data federation technology provides a unified interface to all the available data. The latest version of the portal comes with many new databases that have been created by our ever-growing community. It also comes with better support and extensibility for data analysis and visualization tools. A new addition to our toolbox, the enrichment analysis tool is now accessible through graphical and web service interface. The BioMart community portal averages over one million requests per day. Building on this level of service and the wealth of information that has become available, the BioMart Community Portal has introduced a new, more scalable and cheaper alternative to the large data stores maintained by specialized organizations

Ab initio modeling of optical spectra in pH-sensitive diarylethenes

The photochromic and acidochromic shifts undergone by recently synthesized diarylethene photochromes have been simulated using a Time-Dependent Density Functional Theory approach relying on a range-separated functional, namely CAM-B3LYP. The selected approach is generally accurate for reproducing the variations of the spectral features, though acidochromic shifts are clearly more challenging than their photochromic counterparts. More importantly, an analyzis of the shapes of the relevant molecular orbitals grants insights into the electro-cyclization of several diarylethenes, therefore partly allowing to understand the presence of experimental deadlocks. (C) 2011 Wiley Periodicals, Inc. Int J Quantum Chem, 201

Supramolecular chiral host–guest nanoarchitecture induced by the selective assembly of barbituric acid derivative enantiomers

International audienceBarbituric acid derivatives are prochiral molecules, i.e. they are chiral upon adsorption on surfaces. Scanning tunneling microscopy reveals that barbituric acid derivatives self-assemble into a chiral guest-host supramolecular architecture at the solid-liquid interface on graphite. The host nanoarchitecture has a sophisticated wavy shape pattern and paired guest molecules are nested insides the cavities of the host structure. Each unit cell of the host structure is composed of both enantiomers with a ratio of 1:1. Furthermore, the wavy patterns of the nanoarchitecture are formed from alternative appearance of left- and right-handed chiral building blocks, which makes the network heterochiral. The functional guest-host nanoarchitecture is the result of two-dimensional chiral amplification from single enantiomers to organizational heterochiral supramolecular self-assembly

Etude de la cinétique d'une réaction chimique biologique en présence d'un champ électromagnétique hyperfréquence

LGEP 2010 ID = 64