53 research outputs found

    First Italian-Swiss Meeting on Medicinal Chemistry: Torino, September 23-26, 1997

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    Single nucleotide polymorphisms in northeast European wolves (Canis lupus)

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    In the 1960s, the gray wolf was extinct as a breeding population in Scandinavia. However, in the 1980s a pair was established and started to reproduce in central Sweden. A third wolf, a male, immigrated to Sweden in 1991 contributing to the genetic variation in Scandinavia. Currently the Scandinavian wolf population consists of more than 280 individuals. The population is thus a typical example of a population that has undergone a severe bottleneck. To define the degree of genetic variation in the Scandinavian wolf population thought regions of homozygosity (ROH) and to evaluate possible contribution of immigrant individuals to increase genetic variation on the Swedish population, twenty-three wolves have been genotyped using the 170k canine-specific single nucleotide polymorphism (SNP) array. SNP data was analyzed with PLINK [1] and R [2] software’s

    El enfoque procesual y la competencia traductora. Dos ejes centrales para la mejora de destrezas formativas en la clase de lengua extranjera para traductores e intérpretes

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    [ES]En este artículo se analizarán los elementos básicos que condicionan la formación en lengua extranjera alemana del estudiante de Traducción e Interpretación. Combinamos el eje de dicha formación, el perfeccionamiento de la competencia traductora, con el enfoque procesual centrándonos en el desarrollo de la autonomía del alumno, el análisis de las necesidades del mismo, al igual que en la mejora de la dinámica de clase. Analizaremos a fondo las cuatro destrezas (escuchar - leer - comentar - escribir) y de qué manera se pueden potenciar para que el traductor/intérprete en formación pueda partir de una sólida base lingüística

    The complete genome sequence of Moorella thermoacetica (f. Clostridium thermoaceticum )

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    This paper describes the genome sequence of Moorella thermoacetica (f. Clostridium thermoaceticum ), which is the model acetogenic bacterium that has been widely used for elucidating the Wood–Ljungdahl pathway of CO and CO 2 fixation. This pathway, which is also known as the reductive acetyl-CoA pathway, allows acetogenic (often called homoacetogenic) bacteria to convert glucose stoichiometrically into 3 mol of acetate and to grow autotrophically using H 2 and CO as electron donors and CO 2 as an electron acceptor. Methanogenic archaea use this pathway in reverse to grow by converting acetate into methane and CO 2 . Acetogenic bacteria also couple the Wood–Ljungdahl pathway to a variety of other pathways to allow the metabolism of a wide variety of carbon sources and electron donors (sugars, carboxylic acids, alcohols and aromatic compounds) and electron acceptors (CO 2 , nitrate, nitrite, thiosulfate, dimethylsulfoxide and aromatic carboxyl groups). The genome consists of a single circular 2 628 784 bp chromosome encoding 2615 open reading frames (ORFs), which includes 2523 predicted protein-encoding genes. Of these, 1834 genes (70.13%) have been assigned tentative functions, 665 (25.43%) matched genes of unknown function, and the remaining 24 (0.92%) had no database match. A total of 2384 (91.17%) of the ORFs in the M. thermoacetica genome can be grouped in orthologue clusters. This first genome sequence of an acetogenic bacterium provides important information related to how acetogens engage their extreme metabolic diversity by switching among different carbon substrates and electron donors/acceptors and how they conserve energy by anaerobic respiration. Our genome analysis indicates that the key genetic trait for homoacetogenesis is the core acs gene cluster of the Wood–Ljungdahl pathway.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75588/1/j.1462-2920.2008.01679.x.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/75588/2/EMI_1679_sm_Table_S1-S7_and_Figure_S1-S7.pd

    Eine Figur, viele Rollen

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    Die vorliegende Diplomarbeit befasst sich mit dem Vergleich der verschiedenen Rollen des Ignacio aus Pedro Almodóvars Film „La mala educación“ (2004). Das Ziel dieser Abhandlung liegt darin, die anleitende Forschungsfrage, worin die Gemeinsamkeiten und Unterschiede dieser Rollen liegen, unter Anwendung der formalen Filmanalyse nach Werner Faulstich (2013) und der Figurenanalyse nach Jens Eder ((2014), zu untersuchen. Die Aspekte, in denen sie sich gleichen, wie beispielsweise die Inszenierung der Geschlechtsmerkmale, oder der Einsatz der subjektiven Kameraperspektive, sowie jene, in denen sie sich unterscheiden, etwa die Gegenüberstellung von Männlichkeit und Weiblichkeit, werden mittels der kinematographischen Gestaltungsmittel exemplifiziert und herausgearbeitet. Darüber hinaus beleuchtet die Multi-Identität des Ignacio die Genderthematik, während die Erörterung des Schulalltags in katholischen Internaten deren missbrauchsbegünstigende Strukturen aufzeigt
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