Planck pre-launch status: The optical system

Planck is a scientific satellite that represents the next milestone in space-based research related to the cosmic microwave background, and in many other astrophysical fields. Planck was launched on 14 May of 2009 and is now operational. The uncertainty in the optical response of its detectors is a key factor allowing Planck to achieve its scientific objectives. More than a decade of analysis and measurements have gone into achieving the required performances. In this paper, we describe the main aspects of the Planck optics that are relevant to science, and the estimated in-flight performance, based on the knowledge available at the time of launch. We also briefly describe the impact of the major systematic effects of optical origin, and the concept of in-flight optical calibration. Detailed discussions of related areas are provided in accompanying papers

Planck pre-launch status : The Planck mission

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Digital health technology for use in patients with serious mental illness: a systematic review of the literature

Sonal Batra,1 Ross A Baker,2 Tao Wang,3 Felicia Forma,4 Faith DiBiasi,3 Timothy Peters-Strickland5 1Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, 2Global Medical Affairs, Otsuka Pharmaceutical Development and Commercialization Inc., Princeton, NJ, 3Medical Affairs, Otsuka Pharmaceutical Development and Commercialization Inc., Rockville, MD, 4Health Economics and Outcomes Management, 5Global Clinical Development, Otsuka Pharmaceutical Development and Commercialization Inc., Princeton, NJ, USA Background: As the capabilities and reach of technology have expanded, there is an accompanying proliferation of digital technologies developed for use in the care of patients with mental illness. The objective of this review was to systematically search published literature to identify currently available health technologies and their intended uses for patients with serious mental illness.Materials and methods: The Medline, Embase, and BIOSIS Previews electronic databases were searched to identify peer-reviewed English language articles that reported the use of digital, mobile, and other advanced technology in patients with schizophrenia/schizoaffective disorder, bipolar disorder, and major depressive disorder. Eligible studies were systematically reviewed based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.Results: Eighteen studies that met the inclusion criteria were identified. Digital health technologies (DHTs) assessed in the selected studies included mobile applications (apps), digital medicine, digital personal health records, and an electronic pill container. Smartphone apps accounted for the largest share of DHTs. The intended uses of DHTs could be broadly classified as monitoring to gain a better understanding of illness, clinical assessment, and intervention. Overall, studies indicated high usability/feasibility and efficacy/effectiveness, with several reporting validity against established clinical scales. Users were generally engaged with the DHT, and mobile assessments were deemed helpful in monitoring disease symptoms.Conclusion: Rapidly proliferating digital technologies seem to be feasible for short-term use in patients with serious mental illness; nevertheless, long-term effectiveness data from naturalistic studies will help demonstrate their usefulness and facilitate their adoption and integration into the mental health-care system. Keywords: serious mental illness, health technology, mHealth, smartphone applications, digital medicine&nbsp