66 research outputs found

    Natural Carbon Sequestration in the Commonwealth

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    The Virginia General Assembly created the Carbon Sequestration Task Force in 2021 to examine the feasibility and potential to increase carbon sequestration in the Commonwealth. Specifically, the Task Force must (i) consider possible methods of increasing carbon sequestration within the natural environment through state land and marine resources use policies; agricultural, aquacultural, and silvicultural practices; and other practices to achieve natural resources restoration and long-term conservation; (ii) recommend short-term and long-term benchmarks for increasing carbon sequestration; (iii) develop a standardized methodology to establish baseline carbon levels and account for increases in carbon sequestration over time; (iv) identify existing carbon markets and considerations relevant to potential participation by the Commonwealth; and (v) identify other potential funding mechanisms to encourage carbon sequestration practices in the Commonwealth. The charge required input from both the public and private sector, including many entities that devote time, energy, and resources to achieving Virginia’s clean energy goals for a safer, equitable climate future. The Deputy Secretary of Natural and Historic Resources and the Secretary of Agriculture and Forestry would like to thank the participants in the Carbon Sequestration Task Force for their contributions to a well-grounded, science-based understanding of the potential to increase carbon sequestration through a variety of policy and market strategies... The Virginia Coastal Policy Center and a team of students from William & Mary Law School and the Virginia Institute of Marine Science developed background research for this report and supported the work of the Carbon Sequestration Task Force. This abstract has been adapted from the report\u27s Acknowledgements section

    Modeling the Total Allowable Area for Coastal Reclamation : a case study of Xiamen, China

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    Author Posting. © The Author(s), 2013. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Ocean & Coastal Management 76 (2013):38-44, doi:10.1016/j.ocecoaman.2013.02.015.This paper presents an analytical framework to estimate the Total Allowable Area for Coastal Reclamation (TAACR) to provide scientific support for the implementation of a coastal reclamation restriction mechanism. The logic of the framework is to maximize the net benefits of coastal reclamation subject to a set of constraints. Various benefits and costs, including the ecological and environmental costs of coastal reclamation, are systematically quantified in the framework. Model simulations are developed using data from Tongan Bay of Xiamen. The results suggest that the TAACR in Tongan Bay is 5.67 km2, and the area of the Bay should be maintained at least at 87.52 km2.The study was funded by the National Oceanic Public Welfare Projects (No. 201105006) and the Fujian Natural Science Foundation (No. 2010J01360

    Nanotechnology, governance, and public deliberation: What role for the Social Sciences?

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    In this article we argue that nanotechnology represents an extraordinary opportunity to build in a robust role for the social sciences in a technology that remains at an early, and hence undetermined, stage of development. We examine policy dynamics in both the United States and United Kingdom aimed at both opening up, and closing down, the role of the social sciences in nanotechnologies. We then set out a prospective agenda for the social sciences and its potential in the future shaping of nanotechnology research and innovation processes. The emergent, undetermined nature of nanotechnologies calls for an open, experimental, and interdisciplinary model of social science research

    Policy mixes for incumbency: the destructive recreation of renewable energy, shale gas 'fracking,' and nuclear power in the United Kingdom

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    The notion of a ‘policy mix’ can describe interactions across a wide range of innovation policies, including ‘motors for creation’ as well as for ‘destruction’. This paper focuses on the United Kingdom’s (UK) ‘new policy direction’ that has weakened support for renewables and energy efficiency schemes while strengthening promotion of nuclear power and hydraulic fracturing for natural gas (‘fracking’). The paper argues that a ‘policy apparatus for incumbency’ is emerging which strengthens key regimebased technologies while arguably damaging emerging niche innovations. Basing the discussion around the three technology-based cases of renewable energy and efficiency, fracking, and nuclear power, this paper refers to this process as “destructive recreation”. Our study raises questions over the extent to which policymaking in the energy field is not so much driven by stated aims around sustainability transitions, as by other policy drivers. It investigates different ‘strategies of incumbency’ including ‘securitization’, ‘masking’, ‘reinvention’, and ‘capture.’ It suggests that analytical frameworks should extend beyond the particular sectors in focus, with notions of what counts as a relevant ‘policy maker’ correspondingly also expanded, in order to explore a wider range of nodes and critical junctures as entry points for understanding how relations of incumbency are forged and reproduced

    The Changing Politics and Practice of Child Protection and Safeguarding in England

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    Natural Carbon Sequestration in the Commonwealth

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    The Virginia General Assembly created the Carbon Sequestration Task Force in 2021 to examine the feasibility and potential to increase carbon sequestration in the Commonwealth. Specifically, the Task Force must (i) consider possible methods of increasing carbon sequestration within the natural environment through state land and marine resources use policies; agricultural, aquacultural, and silvicultural practices; and other practices to achieve natural resources restoration and long-term conservation; (ii) recommend short-term and long-term benchmarks for increasing carbon sequestration; (iii) develop a standardized methodology to establish baseline carbon levels and account for increases in carbon sequestration over time; (iv) identify existing carbon markets and considerations relevant to potential participation by the Commonwealth; and (v) identify other potential funding mechanisms to encourage carbon sequestration practices in the Commonwealth. The charge required input from both the public and private sector, including many entities that devote time, energy, and resources to achieving Virginia’s clean energy goals for a safer, equitable climate future. The Deputy Secretary of Natural and Historic Resources and the Secretary of Agriculture and Forestry would like to thank the participants in the Carbon Sequestration Task Force for their contributions to a well-grounded, science-based understanding of the potential to increase carbon sequestration through a variety of policy and market strategies... The Virginia Coastal Policy Center and a team of students from William & Mary Law School and the Virginia Institute of Marine Science developed background research for this report and supported the work of the Carbon Sequestration Task Force. This abstract has been adapted from the report\u27s Acknowledgements section

    In vitro study on the effect of peucedanol on the activity of cytochrome P450 enzymes

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    Peucedanol is a major extract of Peucedanum japonicum Thunb. (Apiaceae) roots, which is a commonly used herb in paediatrics. Its interaction with cytochrome P450 enzymes (CYP450s) would lead to adverse effects or even failure of therapy. The interaction between peucedanol and CYP450s was investigated. Peucedanol (0, 2.5, 5, 10, 25, 50, and 100 μM) was incubated with eight human liver CYP isoforms (CYP1A2, 2A6, 3A4, 2C8, 2C9, 2C19, 2D6, and 2E1), in pooled human liver microsomes (HLMs) for 30 min with specific inhibitors as positive controls and untreated HLMs as negative controls. The enzyme kinetics and time-dependent study (0, 5, 10, 15, and 30 min) were performed to obtain corresponding parameters in vitro. Peucedanol significantly inhibited the activity of CYP1A2, 2D6, and 3A4 in a dose-dependent manner with IC50 values of 6.03, 13.57, and 7.58 μM, respectively. Peucedanol served as a non-competitive inhibitor of CYP3A4 with a Ki value of 4.07 μM and a competitive inhibitor of CYP1A2 and 2D6 with a Ki values of 3.39 and 6.77 μM, respectively. Moreover, the inhibition of CYP3A4 was time-dependent with the Ki/Kinact value of 5.44/0.046 min/μM. In vitro inhibitory effect of peucedanol on the activity of CYP1A2, 2A6, and 3A4 was reported in this study. As these CYPs are involved in the metabolism of various drugs, these results implied potential drug-drug interactions between peucedanol and drugs metabolized by CYP1A2, 2D6, and 3A4, which needs further in vivo validation
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