Noise Abatement and Night Deliveries

ABSTRACT The hypothesis is tested that – Acoustic materials are available or can be developed and applied to Heavy Goods Vehicles and ancillaries, which effectively and economically abate the noise caused by night deliveries The MPhil is a part of a wider innovation research partnership that aimed to develop sustainable solutions for the growing trend to night deliveries in Dublin city centre. The methodology involves; a review of international best practice for urban traffic noise abatement: a social and commercial justification for developing low noise products and procedures: field trials of kerb-side deliveries to city centre shops to identify the “peak” noise events and their associated signature frequencies: an identification of the HGV components and ancillaries to which noise attenuation solutions might best be applied: the selection, matching and pre-screening of suitable acoustic coatings for application to HGV trailer bodies and tail lifts: the development and evaluation of a hush-kit for easy retro-fitting to steel roll-cages. Laboratory and field experiments and special test equipment were designed to support and to validate the research. The research concentrates on bringing forward two sets of solutions (a) the application of an acoustic coating to the HGV trailer unit and tail-lift platform and (b) the development of a hush-kit for the steel roll-cages. The focus is on attenuating the identifiable peak impact noises by matching these with a coating and materials that can dampen the characteristic high frequency sounds. Recommendations are made for further research to optimise the performance of the prototypes developed. ABSTRACT The hypothesis is tested that – Acoustic materials are available or can be developed and applied to Heavy Goods Vehicles and ancillaries, which effectively and economically abate the noise caused by night deliveries The MPhil is a part of a wider innovation research partnership that aimed to develop sustainable solutions for the growing trend to night deliveries in Dublin city centre. The methodology involves; a review of international best practice for urban traffic noise abatement: a social and commercial justification for developing low noise products and procedures: field trials of kerb-side deliveries to city centre shops to identify the “peak” noise events and their associated signature frequencies: an identification of the HGV components and ancillaries to which noise attenuation solutions might best be applied: the selection, matching and pre-screening of suitable acoustic coatings for application to HGV trailer bodies and tail lifts: the development and evaluation of a hush-kit for easy retro-fitting to steel roll-cages. Laboratory and field experiments and special test equipment were designed to support and to validate the research. The research concentrates on bringing forward two sets of solutions (a) the application of an acoustic coating to the HGV trailer unit and tail-lift platform and (b) the development of a hush-kit for the steel roll-cages. The focus is on attenuating the identifiable peak impact noises by matching these with a coating and materials that can dampen the characteristic high frequency sounds. Recommendations are made for further research to optimise the performance of the prototypes developed. ABSTRACT The hypothesis is tested that – Acoustic materials are available or can be developed and applied to Heavy Goods Vehicles and ancillaries, which effectively and economically abate the noise caused by night deliveries The MPhil is a part of a wider innovation research partnership that aimed to develop sustainable solutions for the growing trend to night deliveries in Dublin city centre. The methodology involves; a review of international best practice for urban traffic noise abatement: a social and commercial justification for developing low noise products and procedures: field trials of kerb-side deliveries to city centre shops to identify the “peak” noise events and their associated signature frequencies: an identification of the HGV components and ancillaries to which noise attenuation solutions might best be applied: the selection, matching and pre-screening of suitable acoustic coatings for application to HGV trailer bodies and tail lifts: the development and evaluation of a hush-kit for easy retro-fitting to steel roll-cages. Laboratory and field experiments and special test equipment were designed to support and to validate the research. The research concentrates on bringing forward two sets of solutions (a) the application of an acoustic coating to the HGV trailer unit and tail-lift platform and (b) the development of a hush-kit for the steel roll-cages. The focus is on attenuating the identifiable peak impact noises by matching these with a coating and materials that can dampen the characteristic high frequency sounds. Recommendations are made for further research to optimise the performance of the prototypes developed. ABSTRACT The hypothesis is tested that – Acoustic materials are available or can be developed and applied to Heavy Goods Vehicles and ancillaries, which effectively and economically abate the noise caused by night deliveries The MPhil is a part of a wider innovation research partnership that aimed to develop sustainable solutions for the growing trend to night deliveries in Dublin city centre. The methodology involves; a review of international best practice for urban traffic noise abatement: a social and commercial justification for developing low noise products and procedures: field trials of kerb-side deliveries to city centre shops to identify the “peak” noise events and their associated signature frequencies: an identification of the HGV components and ancillaries to which noise attenuation solutions might best be applied: the selection, matching and pre-screening of suitable acoustic coatings for application to HGV trailer bodies and tail lifts: the development and evaluation of a hush-kit for easy retro-fitting to steel roll-cages. Laboratory and field experiments and special test equipment were designed to support and to validate the research. The research concentrates on bringing forward two sets of solutions (a) the application of an acoustic coating to the HGV trailer unit and tail-lift platform and (b) the development of a hush-kit for the steel roll-cages. The focus is on attenuating the identifiable peak impact noises by matching these with a coating and materials that can dampen the characteristic high frequency sounds. Recommendations are made for further research to optimise the performance of the prototypes developed

Season 2, Episode 2: Check Engine Light

Qiuwei Yang (\u2722) and Jesse Sardell (\u2724) are joined by pediatrician Dr. Heather Finlay-Morreale to discuss her experience of being diagnosed with a chronic illness and how that has influenced the way she cares for her own patients. Recorded April 2021. Dr. Finlay-Morreale\u27s piece Check Engine Light was first published in JAMA Neurology. The transcript for this episode is available for download as an additional file

Late Cretaceous-Eocene exhumation of the northern Lhasa terrane and topographic implications for the Central Tibet

The central Tibetan Plateau has an average altitude of ∼5000 m; its exhumation and chemical weathering greatly influence the global climate and ocean chemistry. The modern central Tibet is characterized by low-relief, high elevation topography with endorheic drainage. When and how these geomorphic characteristics of central Tibet were initiated remains controversial. Here, we have applied zircon Usingle bondPb dating and low-temperature thermochronology on the Cretaceous plutons from Coqin Basin of central Tibet in order to assess timings of exhumation. The thermal history modeling indicates a period of relatively rapid cooling (2.5–4 °C/Ma) occurred in Late Cretaceous to Middle Eocene times (from ∼80 Ma to ∼40 Ma), with the exhumation rates of 0.2–0.4 mm/yr assuming a geothermal gradient of 25 °C/km. Cooling rates then slowed to ∼0.5 °C/Ma during the Middle Eocene to the present, with a relatively lower exhumation rates of ∼0.02–0.03 mm/yr. Synchronous rapid cooling and exhumation has also been identified in central Tibet; this signal of widespread Late Cretaceous exhumation across the region may be viewed as evidence for the initial surface uplift and erosion of the central Tibetan plateau. Lower exhumation rate since ∼40 Ma, combined with sedimentological data suggests that the low-relief, internally drained topography of central Tibet was initiated around this time

The practice of 'doing' evaluation: Lessons learned from nine complex intervention trials in action

Background: There is increasing recognition among trialists of the challenges in understanding how particular 'real-life' contexts influence the delivery and receipt of complex health interventions. Evaluations of interventions to change health worker and/or patient behaviours in health service settings exemplify these challenges. When interpreting evaluation data, deviation from intended intervention implementation is accounted for through process evaluations of fidelity, reach, and intensity. However, no such systematic approach has been proposed to account for the way evaluation activities may deviate in practice from assumptions made when data are interpreted.Methods: A collective case study was conducted to explore experiences of undertaking evaluation activities in the real-life contexts of nine complex intervention trials seeking to improve appropriate diagnosis and treatment of malaria in varied health service settings. Multiple sources of data were used, including in-depth interviews with investigators, participant-observation of studies, and rounds of discussion and reflection.Results and discussion: From our experiences of the realities of conducting these evaluations, we identified six key 'lessons learned' about ways to become aware of and manage aspects of the fabric of trials involving the interface of researchers, fieldworkers, participants and data collection tools that may affect the intended production of data and interpretation of findings. These lessons included: foster a shared understanding across the study team of how individual practices contribute to the study goals; promote and facilitate within-team communications for ongoing reflection on the progress of the evaluation; establish processes for ongoing collaboration and dialogue between sub-study teams; the importance of a field research coordinator bridging everyday project management with scientific oversight; collect and review reflective field notes on the progress of the evaluation to aid interpretation of outcomes; and these approaches should help the identification of and reflection on possible overlaps between the evaluation and intervention.Conclusion: The lessons we have drawn point to the principle of reflexivity that, we argue, needs to become part of standard practice in the conduct of evaluations of complex interventions to promote more meaningful interpretations of the effects of an intervention and to better inform future implementation and decision-making. © 2014 Reynolds et al.; licensee BioMed Central Ltd

Franchises lost and gained: post-coloniality and the development of women’s rights in Canada

The Canadian constitution is to some extent characterised by its focus on equality, and in particular gender equality. This development of women’s rights in Canada and the greater engagement of women as political actors is often presented as a steady linear process, moving forwards from post-enlightenment modernity. This article seeks to disturb this ‘discourse of the continuous,’ by using an analysis of the pre-confederation history of suffrage in Canada to both refute a simplistic linear view of women’s rights development and to argue for recognition of the Indigenous contribution to the history of women’s rights in Canada. The gain of franchise and suffrage movements in Canada in the late nineteenth and early twentieth century are, rightly, the focus of considerable study (Pauker 2015), This article takes an alternative perspective. Instead, it examines the exercise of earlier franchises in pre-confederation Canada. In particular it analyses why franchise was exercised more widely in Lower Canada and relates this to the context of the removal of franchises from women prior to confederation

Clinical outcomes and response to treatment of patients receiving topical treatments for pyoderma gangrenosum: a prospective cohort study

Background: pyoderma gangrenosum (PG) is an uncommon dermatosis with a limited evidence base for treatment. Objective: to estimate the effectiveness of topical therapies in the treatment of PG. Methods: prospective cohort study of UK secondary care patients with a clinical diagnosis of PG suitable for topical treatment (recruited July 2009 to June 2012). Participants received topical therapy following normal clinical practice (mainly Class I-III topical corticosteroids, tacrolimus 0.03% or 0.1%). Primary outcome: speed of healing at 6 weeks. Secondary outcomes: proportion healed by 6 months; time to healing; global assessment; inflammation; pain; quality-of-life; treatment failure and recurrence. Results: Sixty-six patients (22 to 85 years) were enrolled. Clobetasol propionate 0.05% was the most commonly prescribed therapy. Overall, 28/66 (43.8%) of ulcers healed by 6 months. Median time-to-healing was 145 days (95% CI: 96 days, ∞). Initial ulcer size was a significant predictor of time-to-healing (hazard ratio 0.94 (0.88;80 1.00); p = 0.043). Four patients (15%) had a recurrence. Limitations: No randomised comparator Conclusion: Topical therapy is potentially an effective first-line treatment for PG that avoids possible side effects associated with systemic therapy. It remains unclear whether more severe disease will respond adequately to topical therapy alone

Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial

Background: Intensive antiplatelet therapy with three agents might be more effective than guideline treatment for preventing recurrent events in patients with acute cerebral ischaemia. We aimed to compare the safety and efficacy of intensive antiplatelet therapy (combined aspirin, clopidogrel, and dipyridamole) with that of guideline-based antiplatelet therapy. Methods: We did an international, prospective, randomised, open-label, blinded-endpoint trial in adult participants with ischaemic stroke or transient ischaemic attack (TIA) within 48 h of onset. Participants were assigned in a 1:1 ratio using computer randomisation to receive loading doses and then 30 days of intensive antiplatelet therapy (combined aspirin 75 mg, clopidogrel 75 mg, and dipyridamole 200 mg twice daily) or guideline-based therapy (comprising either clopidogrel alone or combined aspirin and dipyridamole). Randomisation was stratified by country and index event, and minimised with prognostic baseline factors, medication use, time to randomisation, stroke-related factors, and thrombolysis. The ordinal primary outcome was the combined incidence and severity of any recurrent stroke (ischaemic or haemorrhagic; assessed using the modified Rankin Scale) or TIA within 90 days, as assessed by central telephone follow-up with masking to treatment assignment, and analysed by intention to treat. This trial is registered with the ISRCTN registry, number ISRCTN47823388. Findings: 3096 participants (1556 in the intensive antiplatelet therapy group, 1540 in the guideline antiplatelet therapy group) were recruited from 106 hospitals in four countries between April 7, 2009, and March 18, 2016. The trial was stopped early on the recommendation of the data monitoring committee. The incidence and severity of recurrent stroke or TIA did not differ between intensive and guideline therapy (93 [6%] participants vs 105 [7%]; adjusted common odds ratio [cOR] 0·90, 95% CI 0·67–1·20, p=0·47). By contrast, intensive antiplatelet therapy was associated with more, and more severe, bleeding (adjusted cOR 2·54, 95% CI 2·05–3·16, p<0·0001). Interpretation: Among patients with recent cerebral ischaemia, intensive antiplatelet therapy did not reduce the incidence and severity of recurrent stroke or TIA, but did significantly increase the risk of major bleeding. Triple antiplatelet therapy should not be used in routine clinical practice