Učinkovitost Forticept® inovativnog proizvoda u higijeni vimena

The quality of cow’s milk and the spread of mastitis greatly depend on the level of udder hygiene. Our author’s research was conducted to evaluate the effects of Forticept® Udder Wash and Forticept® Udder Forte, used before and after milking, on the treatment and prevention of subclinical mastitis and hyperkeratosis of cows’ udders. A total of 6880 milk samples were taken from 430 cows, 3-4 years old, 470-490 kg weight, at 60 ± 15 days of lactation. The therapeutic efficacy coefficient (EC) of Forticept® polymers based on benzetonium and benzalkonium chloride, against the subclinical form of mastitis was 73.8% compared to iodine-containing agents; preventive EC - 32.4%. Dipping hygiene of the udder using Forticept® on the 30th day reduced the number of 1-3 stage teat hyperkeratosis cases from 78.8% to 41.3%. Also, during this period, a significant (P<0.05) improvement in the chemical parameters of the milk was observed - an increase in fat (up to 3.94 ± 0.08%), protein (3.35 ± 0.07%), casein (3.15 ± 0.09%) and dry matter (14.91 ± 0.28%). After using Forticept®, the total bacteria count (TBC) of the milk decreased to 3×105 CFU/cm3, and the somatic cell count (SCC) - to 130 thousand/cm3 (P<0.05). Test day milk yield (TDMY) increased by 1.15% due to efficient dipping with Forticept® (P<0.05).Kvaliteta kravljeg mlijeka i prisutnost mastitisa uvelike ovise o razini higijene vimena. Ovo je istraživanje provedeno kako bi se ustanovila učinkovitost proizvoda Forticept® Udder Wash i Forticept® Udder Forte, upotrijebljenih prije i poslije mužnje, na liječenje i prevenciju supkliničkog mastitisa i hiperkeratoze vimena u krava. Ukupno 6880 uzoraka mlijeka uzeto je od 430 krava, dobi 3 – 4 godine, tjelesne mase 470 – 490 kg, 60. ± 15. dan laktacije. Terapeutski koeficijent učinkovitosti (EC) polimera Forticepta®, temeljen na benzetonijevu i benzalkonijevu kloridu, na supklinički oblik mastitisa bio je 73,8 % u usporedbi s tvarima koje sadržavaju jod a preventivni koeficijent učinkovitosti (EC) 32,4 %. Higijena vimena uranjanjem u Forticept® 30. dan smanjila je broj slučajeva hiperkeratoze bradavica 1. – 3. stadija sa 78,8 % na 41,3 %. Također, u tom je razdoblju uočen znakovit napredak (P < 0,05) u kemijskim pokazateljima mlijeka – porast sadržaja masnoće (do 3,94 ± 0,08 %), proteina (3,35 ± 0,07 %), kazeina (3,15 ± 0,09 %) i suhe tvari (14,91 ± 0,28 %). Nakon upotrebe Forticepta® ukupan broj bakterija (TBC) u mlijeku smanjen je na 3×105 CFU/cm3, a broj somatskih stanica (SCC) na 130 000/cm3 (P < 0,05). Dnevni prinos mlijeka (TDMY) porastao je za 1,15 % zahvaljujući učinkovitoj primjeni Forticepta® (P < 0,05)

Etiology and efficacy of anti-microbial treatment for community-acquired pneumonia in adults requiring hospital admission in Ukraine

Background and aim: Empiric therapy of community-acquired pneumonia (CAP) remains the standard care and guidelines are mostly based on published data from the United States or Europe. In this study, we determined the bacterial etiology of CAP and evaluated the clinical outcomes under antimicrobial treatment of CAP in Ukraine. Methods: A total of 98 adult subjects with CAP and PORT risk II-IV were recruited for the study. The sputum diagnostic samples were obtained from all patients for causative pathogen identification. Subjects were randomly assigned in a 1:1 ratio to receive delafloxacin 300 mg (n=51) or moxifloxacin 400 mg (n=47) with a blinding placebo. The switch to oral treatment was after a minimum of 6 IV doses according to clinical criteria. The total duration of antibacterial treatment was 5-10 days. In vitro susceptibility of pathogens to delafloxacin and other comparator antibiotics was determined. Results: The most frequently isolated pathogens in adults with CAP were S. pneumoniae – 19.5%, M. pneumoniae – 15.3%, H. influenzae – 13.2%, S. aureus – 10.5%, K. pneumoniae – 10.1%, and H. parainfluenzae – 6.4%. All isolates of S. pneumoniae, S. aureus, M. pneumoniae had sufficient susceptibility to appropriate antibiotics. 9.0% of H. influenzae strains were susceptible to azithromycin. 94.8 % of patients had a successful clinical response to delafloxacin at the end of treatment and 93.9 % – at test-of-cure. Conclusions: In Ukraine, the major bacterial agents that induced CAP in adults were S. pneumoniae, M. pneumoniae, H. influenzae, S. aureus, K. pneumoniae, H. parainfluenzae, E. cloacae, L. pneumophila. Delafloxacin is a promising effective antibiotic for monotherapy of CAP in adults and could be used in cases of antimicrobial-resistant strains. (www.actabiomedica.it

Global forest management data for 2015 at a 100 m resolution

Spatially explicit information on forest management at a global scale is critical for understanding the status of forests, for planning sustainable forest management and restoration, and conservation activities. Here, we produce the first reference data set and a prototype of a globally consistent forest management map with high spatial detail on the most prevalent forest management classes such as intact forests, managed forests with natural regeneration, planted forests, plantation forest (rotation up to 15 years), oil palm plantations, and agroforestry. We developed the reference dataset of 226 K unique locations through a series of expert and crowdsourcing campaigns using Geo-Wiki (https://www.geo-wiki.org/). We then combined the reference samples with time series from PROBA-V satellite imagery to create a global wall-to-wall map of forest management at a 100 m resolution for the year 2015, with forest management class accuracies ranging from 58% to 80%. The reference data set and the map present the status of forest ecosystems and can be used for investigating the value of forests for species, ecosystems and their services

Current increment of ecosystem services in permanent sample plots within the forest stands of the Feofania park-monument

Despite the fact that forests in nature conservation areas are of mature and over-mature age, they have a leading role in the production of ecosystem services, in particular in ensuring biodiversity. In the typical sense, at the mature and over-mature age of stands, the growth of live biomass and carbon sequestration almost stops, and the death of trees leads to a negative change in the stock. The purpose of the study is to substantiate the ability of over-mature forests to accumulate live biomass under the condition of the formation of multi-tiered and different-age stands. The research was conducted on four permanent sample plots of the Feofania park-monument, which were established in 2016 and 2017. The method of approximate mensuration was used to study the current growth of ecosystem services. The method of dendrochronology was used to analyse annual rings. The age range of experimental stands is between 80 and 180 years. Experimental stands of all sample plots are characterized by high-level productivity, compared to model data on the productivity of stands in Ukraine and the European part of Eurasia. According to the results of the research, it was established that the biggest current increment of ecosystem services is formed in the uneven-aged stand with the centuries-old common oak trees of the overstory. The results of the research can be used in practice for the management of nature conservation areas and improvement of the management of over-mature forest

Global forest management data for 2015 at a 100 m resolution

Spatially explicit information on forest management at a global scale is critical for understanding the status of forests, for planning sustainable forest management and restoration, and conservation activities. Here, we produce the first reference data set and a prototype of a globally consistent forest management map with high spatial detail on the most prevalent forest management classes such as intact forests, managed forests with natural regeneration, planted forests, plantation forest (rotation up to 15 years), oil palm plantations, and agroforestry. We developed the reference dataset of 226 K unique locations through a series of expert and crowdsourcing campaigns using Geo-Wiki (https://www.geo-wiki.org/). We then combined the reference samples with time series from PROBA-V satellite imagery to create a global wall-to-wall map of forest management at a 100 m resolution for the year 2015, with forest management class accuracies ranging from 58% to 80%. The reference data set and the map present the status of forest ecosystems and can be used for investigating the value of forests for species, ecosystems and their services

ALICE Electromagnetic Calorimeter Technical Design Report

The ALICE Electromagnetic Calorimeter technical design is reported