Deciphering top flavor violation at the LHC with B factories

The LHC will have unprecedented sensitivity to flavor-changing neutral current (FCNC) top quark decays, whose observation would be a clear sign of physics beyond the standard model. Although many details of top flavor violation are model dependent, the standard model gauge symmetries relate top FCNCs to other processes, which are strongly constrained by existing data. We study these constraints in a model independent way, using a low energy effective theory from which the new physics is integrated out. We consider the most important operators which contribute to top FCNCs and analyze the current constraints on them. We find that the data rule out top FCNCs at a level observable at the LHC due to most of the operators comprising left-handed first or second generation quark fields, while there remains a substantial window for top decays mediated by operators with right-handed charm or up quarks. If FCNC top decays are observed at the LHC, such an analysis may help decipher the underlying physics.Comment: 17 pages, 5 figures; some typos correcte

Investigating an API for resilient exascale computing.

Increased HPC capability comes with increased complexity, part counts, and fault occurrences. In- creasing the resilience of systems and applications to faults is a critical requirement facing the viability of exascale systems, as the overhead of traditional checkpoint/restart is projected to outweigh its bene ts due to fault rates outpacing I/O bandwidths. As faults occur and propagate throughout hardware and software layers, pervasive noti cation and handling mechanisms are necessary. This report describes an initial investigation of fault types and programming interfaces to mitigate them. Proof-of-concept APIs are presented for the frequent and important cases of memory errors and node failures, and a strategy proposed for lesystem failures. These involve changes to the operating system, runtime, I/O library, and application layers. While a single API for fault handling among hardware and OS and application system-wide remains elusive, the e ort increased our understanding of both the mountainous challenges and the promising trailheads.

Late Holocene dietary and cultural variability on the Xingu River, Amazon Basin:A stable isotopic approach

Although once considered a ‘counterfeit paradise’, the Amazon Basin is now a region of increasing interest in discussions of pre-colonial tropical land-use and social complexity. Archaeobotany, archaeozoology, remote sensing and palaeoecology have revealed that, by the Late Holocene, populations in different parts of the Amazon Basin were using various domesticated plants, modifying soils, building earthworks, and even forming ‘Garden Cities’ along the Amazon River and its tributaries. However, there remains a relatively limited understanding as to how diets, environmental management, and social structures varied across this vast area. Here, we apply stable isotope analysis to human remains (n = 4 for collagen, n = 17 for tooth enamel), and associated fauna (n = 61 for collagen, n = 28 for tooth enamel), to directly determine the diets of populations living in the Volta Grande do Rio Xingu, an important region of pre-Columbian cultural interactions, between 390 cal. years BC and 1,675 cal. years AD. Our results highlight an ongoing dietary focus on C3 plants and wild terrestrial fauna and aquatic resources across sites and time periods, with varying integration of C4 plants (i.e. maize). We argue that, when compared to other datasets now available from elsewhere in the Amazon Basin, our study highlights the development of regional adaptations to local watercourses and forest types.Introduction Background - Environmental and cultural contexts of the Xingu River - Isotope analysis in the tropics Materials and methods - Archaeological sites - Samples - Stable isotope analysis - Statistical analysis Results - Radiocarbon dating - δ13Cco and δ15N from collagen - δ13Cca and δ18O from enamel bioapatite Discussion - Amazonian baselines - Diets on the Xingu River between 390 cal. BC and 1,675 cal. years AD - Comparison with other Amazon datasets Conclusion

Dilatonic current-carrying cosmic strings

We investigate the nature of ordinary cosmic vortices in some scalar-tensor extensions of gravity. We find solutions for which the dilaton field condenses inside the vortex core. These solutions can be interpreted as raising the degeneracy between the eigenvalues of the effective stress-energy tensor, namely the energy per unit length U and the tension T, by picking a privileged spacelike or timelike coordinate direction; in the latter case, a phase frequency threshold occurs that is similar to what is found in ordinary neutral current-carrying cosmic strings. We find that the dilaton contribution for the equation of state, once averaged along the string worldsheet, vanishes, leading to an effective Nambu-Goto behavior of such a string network in cosmology, i.e. on very large scales. It is found also that on small scales, the energy per unit length and tension depend on the string internal coordinates in such a way as to permit the existence of centrifugally supported equilibrium configuration, also known as vortons, whose stability, depending on the very short distance (unknown) physics, can lead to catastrophic consequences on the evolution of the Universe.Comment: 10 pages, ReVTeX, 2 figures, minor typos corrected. This version to appear in Phys. Rev.

ANÁLISE NÃO-LINEAR DA CONTRIBUIÇÃO DE ARMADURAS COMPLEMENTARES NA RESISTÊNCIA AO ARRANCAMENTO DE PINOS EMBUTIDOS EM CONCRETO

Conectores de aço com cabeça são empregados na ligação entre estruturas mistas de aço e concreto e em estruturas pré-moldadas. Quando solicitados à tração, a resistência ao arrancamento é fator determinante no projeto e o modo de ruptura pela formação do cone de concreto pode ser frágil. Uma das formas de aumentar a resistência dessa ligação é utilizar armaduras complementares. Para avaliar a influência da armadura complementar na resistência ao arrancamento, foram elaborados 6 modelos computacionais não-lineares em EPD no programa MIDAS FEA, com base em uma série de ensaios experimentais de conectores embutidos em vigotas de concreto armado. A modelagem buscou avaliar a influência do diâmetro da armadura complementar, do número de pernas interceptando o cone de concreto e da distância do conector até da armadura complementar. Foi realizado um estudo paramétrico para ajustar as propriedades do concreto, variando a resistência à tração, módulo de elasticidade e a energia de fratura. A análise computacional realizada apresenta tabelas com carga de ruptura, gráficos de carga x deslocamento, carga x deformação na armadura longitudinal e carga x deformação na armadura transversal, de forma geral se apresentando em boa concordância com os resultados experimentais

Sketch-based interaction and modeling: where do we stand?

Sketching is a natural and intuitive communication tool used for expressing concepts or ideas which are difficult to communicate through text or speech alone. Sketching is therefore used for a variety of purposes, from the expression of ideas on two-dimensional (2D) physical media, to object creation, manipulation, or deformation in three-dimensional (3D) immersive environments. This variety in sketching activities brings about a range of technologies which, while having similar scope, namely that of recording and interpreting the sketch gesture to effect some interaction, adopt different interpretation approaches according to the environment in which the sketch is drawn. In fields such as product design, sketches are drawn at various stages of the design process, and therefore, designers would benefit from sketch interpretation technologies which support these differing interactions. However, research typically focuses on one aspect of sketch interpretation and modeling such that literature on available technologies is fragmented and dispersed. In this paper, we bring together the relevant literature describing technologies which can support the product design industry, namely technologies which support the interpretation of sketches drawn on 2D media, sketch-based search interactions, as well as sketch gestures drawn in 3D media. This paper, therefore, gives a holistic view of the algorithmic support that can be provided in the design process. In so doing, we highlight the research gaps and future research directions required to provide full sketch-based interaction support

ANÁLISE NÃO LINEAR DA INFLUÊNCIA DA FISSURAÇÃO NA RESISTÊNCIA AO ARRANCAMENTO DE PINOS EMBUTIDOS EM CONCRETO

Quando conectores de aço com cabeça são solicitados à tração, uma forma de ruptura é ocasionada pelo destacamento de uma região de concreto em torno do conector, em formato de cone. Sabe-se que o aumento do grau de fissuração na região do cone influencia negativamente na resistência do conjunto. Este trabalho apresenta uma modelagem computacional com base em uma série de ensaios experimentais caracterizados pelo arrancamento de conectores de aço embutidos em prismas bi-apoiados de concreto armado. A modelagem visou avaliar a influência do grau de fissuração na resistência do conjunto, onde variou-se a taxa de armadura de flexão de 0,3 até 3,2% entre os modelos, resultando em diferentes graus de fissuração. A análise numérica foi realizada usando o software MIDAS FEA. Foi feito um estudo paramétrico em um dos modelos, para ajustar as propriedades do concreto, sendo os alvos do estudo a resistência à tração, o módulo de elasticidade e a energia de fratura. Os valores definidos na análise foram extrapolados para os outros modelos. Foram determinadas cargas de ruptura e gráficos de carga x deslocamento para os modelos numéricos. Tais resultados foram comparados com os resultados experimentais, apresentando boa correlação, v dos modelos computacionais

Researching AI Legibility Through Design

Everyday interactions with computers are increasingly likely to involve elements of Artificial Intelligence (AI). Encompassing a broad spectrum of technologies and applications, AI poses many challenges for HCI and design. One such challenge is the need to make AI’s role in a given system legible to the user in a meaningful way. In this paper we employ a Research through Design (RtD) approach to explore how this might be achieved. Building on contemporary concerns and a thorough exploration of related research, our RtD process reflects on designing imagery intended to help increase AI legibility for users. The paper makes three contributions. First, we thoroughly explore prior research in order to critically unpack the AI legibility problem space. Second, we respond with design proposals whose aim is to enhance the legibility, to users, of systems using AI. Third, we explore the role of design-led enquiry as a tool for critically exploring the intersection between HCI and AI research

A relocatable ocean model in support of environmental emergencies

During the Costa Concordia emergency case, regional, subregional, and relocatable ocean models have been used together with the oil spill model, MEDSLIK-II, to provide ocean currents forecasts, possible oil spill scenarios, and drifters trajectories simulations. The models results together with the evaluation of their performances are presented in this paper. In particular, we focused this work on the implementation of the Interactive Relocatable Nested Ocean Model (IRENOM), based on the Harvard Ocean Prediction System (HOPS), for the Costa Concordia emergency and on its validation using drifters released in the area of the accident. It is shown that thanks to the capability of improving easily and quickly its configuration, the IRENOM results are of greater accuracy than the results achieved using regional or subregional model products. The model topography, and to the initialization procedures, and the horizontal resolution are the key model settings to be configured. Furthermore, the IRENOM currents and the MEDSLIK-II simulated trajectories showed to be sensitive to the spatial resolution of the meteorological fields used, providing higher prediction skills with higher resolution wind forcing.MEDESS4MS Project; TESSA Project; MyOcean2 Projectinfo:eu-repo/semantics/publishedVersio

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

Allergic rhinitis is the most common clinical presentation of allergy, affecting 400 million people worldwide, with increasing incidence in westernized countries1,2. To elucidate the genetic architecture and understand the underlying disease mechanisms, we carried out a meta-analysis of allergic rhinitis in 59,762 cases and 152,358 controls of European ancestry and identified a total of 41 risk loci for allergic rhinitis, including 20 loci not previously associated with allergic rhinitis, which were confirmed in a replication phase of 60,720 cases and 618,527 controls. Functional annotation implicated genes involved in various immune pathways, and fine mapping of the HLA region suggested amino acid variants important for antigen binding. We further performed genome-wide association study (GWAS) analyses of allergic sensitization against inhalant allergens and nonallergic rhinitis, which suggested shared genetic mechanisms across rhinitis-related traits. Future studies of the identified loci and genes might identify novel targets for treatment and prevention of allergic rhinitis