1,958 research outputs found
Theoretical approaches in subject information organization: an analysis of the presence of subject cataloguing and indexing matters in ISKO-Spain literature
[Resumo]
O Tratamento Temático da Informação ? TTI, na Biblioteconomia e Documentação, possui natureza
mediadora, pois propicia interlocução dos contextos de produção e de uso da informação por meio da
análise, descrição e representação do conteúdo dos documentos para armazenamento e recuperação da
informação em cujo âmbito se desenvolvem processos, instrumentos e produtos. Essa área de estudos
se apresenta, teoricamente, sob três vertentes: catalogação de assunto, de matriz norte-americana, e
indexação, de matriz inglesa, mais centradas nos instrumentos e produtos de TTI, e análise documental, de
matriz francesa, mais voltada para os procedimentos envolvidos no TTI. Nesse contexto, e considerando
que o capítulo espanhol da ISKO atua como um importante e consolidado espaço científico de discussões
acadêmicas sobre o TTI, notadamente no âmbito ibero-americano, procede-se a uma análise de domínio
das correntes teóricas de matriz anglo-saxônica ? Indexação e Catalogação de Assunto ? nas comunicações
apresentadas nos nove congressos de ISKO-España até então realizados, para identificar sua presença,
sua articulação e seus referentes teóricos como subsídio aos estudos epistemológicos em organização do
conhecimento.[Abstract]
Subject information organization has a capital position in the Library and Documentation field since it
promotes a dialogical dimension (or sometimes a bridge) between the information production and the information use by means of set of special activities like subject analysis, description and representation
in order to promote information retrieval. Such branch of studies presents can be presented by means
of different theoretical approaches. In this sense, the anglo-saxon approaches ? subject cataloguing
and indexing ? are more devoted to the development of indexing languages and catalogues while the
French-oriented approach - analyse documentaire - denotes a bigger concern on the procedures involved.
Considering that the Spanish chapter of ISKO has been acting as an important scientific in knowledge
organization matters (including subject information organization) specially in the Ibero-American
countries, it carries out an analysis of the presence of the mentioned Anglo-saxon approaches - subject
cataloguing and indexing ? in the papers presented at the ISKO-Spain congresses already occurred in
order to identify the scientific articulation degree among their theoretical referents as a subsidy to the
epistemological studies in knowledge organization in Spain
A critical review on the performance of pile-supported rail embankments under cyclic loading: Numerical modeling approach
Searching for economical and practical solutions to increase any transport substructures protection and stability is critical for ensuring the long-term viability and adequate load-bearing capacity. Piles are increasingly being used as an economical and environmentally sustainable solution to enhance the strength of soft subgrade soils on which embankments are raised. As per the available literature, there are two main strategies used to explain railway embankments performance: experimental approaches and numerical simulations on a broad scale. The purpose of this study is to examine the state-of-the-art literature on numerical modeling methods adopted to assess the performance of pile-supported rail embankments subjected to cyclic loading. The paper addresses the main results from various numerical methods to explain the appropriate mechanisms associated with the load deformation response. It also presents the key issues and drawbacks of these numerical methods concerning rail embankment development while outlining the specific shortcomings and research gaps relevant to enhanced future design and analysis. (c) 2021 by the authors. Licensee MDPI, Basel, Switzerland
Lexical Predictability during Natural Reading: Effects of Surprisal and Entropy Reduction
What are the effects of word‐by‐word predictability on sentence processing times during the natural reading of a text? Although information complexity metrics such as surprisal and entropy reduction have been useful in addressing this question, these metrics tend to be estimated using computational language models, which require some degree of commitment to a particular theory of language processing. Taking a different approach, this study implemented a large‐scale cumulative cloze task to collect word‐by‐word predictability data for 40 passages and compute surprisal and entropy reduction values in a theory‐neutral manner. A separate group of participants read the same texts while their eye movements were recorded. Results showed that increases in surprisal and entropy reduction were both associated with increases in reading times. Furthermore, these effects did not depend on the global difficulty of the text. The findings suggest that surprisal and entropy reduction independently contribute to variation in reading times, as these metrics seem to capture different aspects of lexical predictability
Humibacter albus gen. nov., sp. nov., isolated from sewage sludge compost
A bacterial strain isolated from sewage sludge compost, strain SC-083T, was characterized. The isolate was a motile, Gram-positive, short rod, forming coryneform V-shaped cells during the early stages of growth. The organism was strictly aerobic and able to grow between 22 and 36 °C and between pH 5.5 and 8.0. The predominant fatty acids were cyclohexyl-C17 : 0, anteiso-C17 : 0 and iso-C16 : 0, the major respiratory quinones were menaquinone 11 (MK-11) and 12 (MK-12), and the genomic DNA G+C content was 68 mol%. The peptidoglycan contained the diagnostic diamino acids ornithine and 2,4-diaminobutyric acid and was of acetyl type. The 16S rRNA gene sequence analysis indicated that this isolate belongs to the family Microbacteriaceae with the type strains of the species Leifsonia xyli (96 % gene sequence similarity), Leifsonia shinshuensis (96 %), Leifsonia naganoensis (95 %), Leifsonia aquatica (95 %), Agromyces ramosus (95 %) and Curtobacterium citreum (95 %) among the closest phylogenetic neighbours. The phylogenetic analysis and phenetic characteristics support the proposal of a new genus and a novel species, with the name Humibacter albus gen. nov., sp. nov. The type strain of Humibacter albus is SC-083T (=DSM 18994T =CCUG 54538T =LMG 23996T
Effects of combined training on metabolic profile, lung function, stress and quality of life in sedentary adults: a study protocol for a randomized controlled trial
Background
Both physical inactivity and sedentary behavior are considered modifiable risk factors for chronic diseases and all-cause mortality. Adult office-workers spend most of their working day in sedentary behaviors, so they are particularly at high risk of developed chronic diseases (e.g., cardiovascular diseases, metabolic disorders like diabetes mellitus, . . .). It seems important to promote behavioral changes that could prevent or delay metabolic disease development. Evidence supports the use of exercise programs, however, to date there are several knowledge gaps and inconsistencies in the literature regarding the effects of Combined Training (i.e., aerobic plus resistance training) in sedentary healthy adults. This paper outlines an RCT designed to evaluate the effects of a 16-week combined training program on biochemical and immune markers of metabolic disease, lung function, salivary stress hormones and subjective quality of life (primary outcomes), as well as on body composition and physical fitness (secondary outcomes) in sedentary middle-aged office-workers. Furthermore, we aimed to assess the associations between the changes promoted by the exercise program and the different variables studied.
Methods and design
This is a single-blinded two-arm RCT with parallel groups. A minimum of healthy 40 officeworkers aged 40–64 years will be recruited to engage in a 16-week intervention study. After baseline assessments, participants will be randomized to one of the two groups: (1) combined training group or (2) control group. Baseline assessments will be repeated after 8 weeks of intervention (mid-testing) and upon completion of the intervention (post-testing).
Discussion
This RCT involves a multi-disciplinary approach and seems to be a relevant contribution to understanding the potential role of combined training in improving the metabolic profile, lung function, stress, and quality of life in adults. The results can provide important insights for clinical recommendations and for the optimization of strategies to prevent metabolic disorders in adults with sedentary jobs.info:eu-repo/semantics/publishedVersio
Antimicrobial activity of phenolic extracts of Eucalyptus globulus and Juglans regia against dairy industry pathogens
Book of Abstracts of CEB Annual Meeting 2017[Excerpt] Bovine mastitis (BM) is the most expensive pathology for dairy industry and Staphylococcus aureus is amongst the most prevalent causative agents of this disease. Nowadays, it is known that S. aureus contaminated milk can enter the dairy production chain and be the origin of food contamination. Due to the poor efficacy of antibiotics and to the ability to form biofilms evidenced by this pathogen, BM has become increasingly difficult to control and to eradicate. Phenolic plant extracts are nowadays being evaluated since they are a rich source of bioactive molecules. Thus, in this work the antimicrobial activity of E. globulus and J. regia alone and in combination against S. aureus BM isolates was evaluated and compared with penicillin G (Pen G), an antibiotic commonly used in the treatment of this pathology. The evaluation of the cytotoxic potential of both extracts was also performed. [...]info:eu-repo/semantics/publishedVersio
Química mineral de encraves ultramáficos nas lavas da erupção de 2014 na Ilha do Fogo (Cabo Verde) : resultados preliminares
Resumo alargad
Mentha aquatica L. extract effects on mitochondrial bioenergetics
Mentha aquatica (water mint) extracts are regularly used in food flavoring and pharmacology. In the present study, the possible effects of an ethanolic extract from leaves of M. aquatica L. on rat liver mitochondria bioenergetics were evaluated.
The plant extract (25 μg·mg protein−1) but not the vehicle, inhibited the mitochondrial oxidative system, as seen by a depression
of respiration (state 3, respiratory control ratio (RCR), FCCP stimulated respiration) and lower generation of the transmembrane
electric potential using glutamate+malate and succinate as respiratory substrates. The depressing effects in oxidative phosphorylation can probably be related with the polyphenolic composition of the extract
(mainly eriodictyol-7-O-rutinoside, luteolin-7-O-rutinoside, naringenin-
7-O-rutinoside, hesperitin-7-O-rutinoside and rosmarinic acid) that can interact with membrane and change the inner mitochondrial membrane lipidic moiety. Despite decreasing the RCR, the presence of M. aquatica extract did not affect the mitochondrial phosphorylative capacity, as estimated by the ADP/O ratio. No significant increase in inner mitochondrial membrane permeability was observed and induction of mitochondrial permeability transition pore was not altered in the range of concentrations tested (up to 25 μg·mg protein−1) either. For the highest concentrations tested (25 μg·mg protein−1 or higher) the inhibition observed on the mitochondrial respiratory chain, as reflected
by FCCP-stimulated respiration, revealed that M. aquatica ethanolic extract is toxic for mitochondrial bioenergetics. In conclusion, the presente study suggests that a high daily consumption of an ethanolic extract of M. aquatica leaves should be regarded as hazardous
The role of benralizumab in eosinophilic immune dysfunctions: a case report-based literature review
In the past years, the knowledge of eosinophils playing a primary pathophysiologic role in several associated conditions has led to the development of biologics targeting therapies aiming at normalizing the immune response, reducing chronic inflammation, and preventing tissue damage. To better illustrate the potential relationship between different eosinophilic immune dysfunctions and the effects of biological therapies in this scenario, here, we present a case of a 63-year-old male first referred to our department in 2018 with a diagnosis of asthma, polyposis, and rhinosinusitis and presenting a suspicion of nonsteroidal anti-inflammatory drugs' allergy. He also had a past medical history of eosinophilic gastroenteritis/duodenitis (eosinophilia counts >50 cells/high-power field HPF). The use of multiple courses of corticosteroid therapy failed to completely control these conditions. In October 2019, after starting benralizumab (an antibody directed against the alpha chain of the IL-5 cytokine receptor) as an add-on treatment for severe eosinophilic asthma, important clinical improvements were reported both in the respiratory (no asthma exacerbations) and gastrointestinal systems (eosinophilia count 0 cells/HPF). The patient's quality of life also increased. Since June 2020, systemic corticosteroid therapy was reduced without worsening gastrointestinal symptoms or eosinophilic inflammation. This case warns of the importance of early recognition and appropriate individualized treatment of eosinophilic immune dysfunctions and suggests the conduction of further larger studies on the use of benralizumab in gastrointestinal syndromes aiming at better understanding its relying mechanisms of action in the intestinal mucosa.info:eu-repo/semantics/publishedVersio
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