Gender identity assessment with trans individuals – findings of a systematic literature review of assessment instruments and ethical considerations

Purpose In several Western legislations, trans individuals must frequently undergo some form of gender identity assessment, for example, to receive legal recognition of their gender or to access therapeutic interventions. Thus, a standardised and empirically supported assessment approach becomes necessary. The purpose of this paper is to critically reflect on the current international guidelines for assessments by the World Professional Association for Transgender Health, which will be compared to standards in secure forensic settings, illustrated by British prison policies. Design/methodology/approach Findings of a systematic literature review following preferred reporting items for systematic reviews and meta-analysis standards are presented, summarising the current state of research pertaining to gender identity assessment instruments. Studies were included, when they presented empirical details pertaining to assessment approaches and passed the quality appraisal, but were excluded when they did not use a trans sample or presented clinical assessments not linked to gender identity. Findings A total of 21 included English articles, which mostly have been published in the USA in the past 20 years, propose ten different assessment approaches. Most of the studies support the use of the Minnesota Multiphasic Personality Inventory-2, the Bem Sex-Role Inventory, Body Image Scale for Transsexuals and the Gender Identity/Gender Dysphoria Questionnaire for Adolescents and Adults. The instruments are briefly summarised. Practical implications It becomes apparent that this field is severely understudied and that there is no consensus regarding the best assessment approach. Hence, any recommendations are only preliminary and are contextualised with further ethical considerations and suggestions for future research. Originality/value To the best of the author’s knowledge, this is the first systematic literature review pertaining to the (semi-)structured assessment of gender identity

Effect of temperature on RC elements strengthened with CFRP

The strengthening of RC elements with CFRP is a technique that has been acquiring more and more potential. The bond between the CFRP reinforcement and the concrete support is usually made with epoxy adhesives. However, it is here that the integrity of the system can be affected, namely by exposure to high temperatures. In order to study the effect of an increase of air temperature on the behaviour of the epoxy adhesive, CFRP strengthened RC and reference RC specimens were tested. After cyclical thermal exposures, with temperatures rising between 20ºC and 80ºC, specimens were subjected either to compressive shear tests or bending tests. The results demonstrated that epoxy adhesive exhibits poor behaviour when subjected to increased temperatures, causing important bond deterioration. The improvement achieved with the CFRP reinforcement tends to disappear with an increase of the environment temperature. So, the thermal resistance of this strengthened system can not be considered very high. However, the inclusion of insulating materials can be a good solution to protect the strengthened RC elements. Among tested materials, the foamed polyurethane showed the best behaviour

Towards Resilience to Nuclear Accidents:Financing Nuclear Liabilities via Catastrophe Risk Bonds

In light of the 2011 Fukushima disaster, recent discussion has focused on finding the best nuclear storage options, maximizing the oversight power of global institutions, and strengthening safety measures. In addition to these, the development of dependable liability coverage that can be tapped in an emergency is also needed and should be considered thoughtfully. To succeed, financing is essential using special-purpose instruments from the global bond market, which is as big as US$175 trillion. Thus, in this paper, for the first time, a two-coverage-type trigger nuclear catastrophe (N-CAT) risk bond for potentially supplementing the covering of U.S. commercial nuclear power plants (NPPs) beyond the coverage per the Price Anderson Act as amended, and potentially other plants are proposed and designed worldwide. The N-CAT peril is categorized by three risk layers: incident, accident, and major accident. The pricing formula is derived by using a semi-Markovian dependence structure in continuous time. A numerical application illustrates the main findings of the paper.</jats:p

Decay of escherichia coli in soil following the application of biosolids to agricultural land

The decay of Escherichia coli in a sandy loam soil, amended with enhanced and conventionally treated biosolids, was investigated in a field experiment following spring and autumn applications of sewage sludge. Control soils, without the application of biosolids, were also examined to determine the background indigenous populations of E. coli which are present in the environment. The survival of indigenous E. coli and populations of E. coli applied to soil in biosolids, is assessed in relation to environmental factors influencing pathogen-decay processes in soil

Diagnosing fibrotic lung disease: When is high-resolution computed tomography sufficient to make a diagnosis of idiopathic pulmonary fibrosis?

Idiopathic pulmonary fibrosis (IPF), a progressive and fatal diffuse parenchymal lung disease, is defined pathologically by the pattern of usual interstitial pneumonia (UIP). Unfortunately, a surgical lung biopsy cannot be performed in all patients due to comorbidities that may significantly increase the morbidity and mortality of the procedure. High-resolution computed tomography (HRCT) has been put forth as a surrogate to recognize pathological UIP. The quality of the HRCT impacts the ability to make a diagnosis of UIP and varies based on the centre performing the study and patient factors. The evaluation of the HRCT includes assessing the distribution and predominance of key radiographical findings, such as honeycomb, septal thickening, traction bronchiectasis and ground glass attenuation lesions. The combination of the pattern and distribution is what leads to a diagnosis and associated confidence level. HRCT features of definite UIP (subpleural, basal predominant honeycomb with septal thickening, traction bronchiectasis and ground glass attenuation lesions) have a high specificity for the UIP pathological pattern. In such cases, surgical lung biopsy can be avoided. There are caveats to using the HRCT to diagnose IPF in isolation as a variety of chronic pulmonary interstitial diseases may progress to a UIP pattern. Referral centres with experience in diffuse parenchymal lung disease that have multidisciplinary teams encompassing clinicians, radiologists and pathologists have the highest level of agreement in diagnosing IPF.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75246/1/j.1440-1843.2009.01626.x.pd

A numerical investigation on the fire response of a steel girder bridge

The response of bridges subject to fire is an under researched topic despite the number of bridge failures caused by fire. Since available data shows that steel girder bridges are especially vulnerable to fire, this paper delves into their fire response by analyzing with a 3D numerical model the response of a typical bridge of 12.20 m span length. A parametric study is performed considering: (1) two possibilities for the axial restraint of the bridge deck, (2) four types of structural steel for the girders (carbon steel and stainless steel grades 1.4301, 1.4401, and 1.4462), (3) three different constitutive models for carbon steel, (4) four live loads, and (5) two alternative fire loads (the hydrocarbon fire defined by Eurocode 1 and a fire corresponding to a real fire event). Results show that restraint to deck expansion coming from an adjacent span or abutment should be considered in the numerical model. In addition, times to collapse are very small when the bridge girders are built with carbon steel (between 8.5 and 18 min) but they can almost double if stainless steel is used for the girders. Therefore, stainless steel is a material to consider for steel girder bridges in a high fire risk situation, especially if the bridge is located in a corrosive environment and its aesthetics deserves special attention. The methodology developed in this paper and the results obtained are useful for researchers and practitioners interested in developing and applying a performance-based approach for the design of bridges against fire. © 2012 Elsevier Ltd. All rights reserved.Funding for this research has been provided to Dr. Paya-Zaforteza by the Spanish Ministry of Education (contract number EX-2008-0669 of the Program for Postdoctoral Stays), the Spanish Ministry of Economy and Competitiveness (research project BIA 2011-27104) and the Universitat Politecnica de Valencia (Research and Development Support Program PAID-06-11). Funding has also been provided to Dr. Maria Garlock by the National Science Foundation (NSF) under award number CMMI-1068252. All opinions expressed in this paper are the authors' and do not necessarily reflect the policies and views of the sponsors.Paya-Zaforteza, I.; Garlock, ME. (2012). A numerical investigation on the fire response of a steel girder bridge. Journal of Constructional Steel Research. 75:93-103. https://doi.org/10.1016/j.jcsr.2012.03.012S931037

Effects of Multiday Exposure to Ozone on Airway Inflammation as Determined Using Sputum Induction

Single short-term exposures to ozone are known to cause acute changes in pulmonary function and neutrophilic airway inflammation. The respiratory health effects of repeated exposures are not as well studied. Pulmonary function decrements are known to attenuate, but it is less clear how injury and inflammation are affected. Using sputum induction (SI) to sample respiratory tract lining fluid after single- and multiday exposures, we designed a study to test the hypothesis that neutrophils would increase after multiday exposure compared with single-day exposure. In a randomized, crossover design, 15 normal healthy subjects were exposed to O(3) (0.2 ppm) under two conditions: for 4 hr for 1 day (1D) and for 4 hr for 4 consecutive days (4D). Pulmonary function testing was performed immediately before and after each 4-hr exposure. The SI was performed 18 hr after the end of the 1D and 4D conditions. The symptom and pulmonary function data followed a pattern seen in other multiday O(3) exposure studies, with the greatest changes occurring on the second day. In contrast to previous studies using bronchoalveolar lavage, however, there was a significant increase in the percentage of neutrophils and a significant decrease in the percentage of macrophages after the 4D condition compared with the 1D condition. Given that SI likely samples proximal airways better than distal lung, these results add to the body of evidence that differential airway compartmental responses to O(3) occur in humans and other species

Application of diffusion-edited and solvent suppression 1H NMR to the direct analysis of markers in valerian-hop liquid herbal products

This is the peer reviewed version of the following article: Jose M. Prieto, Maria Mellinas-Gomez, Mire Zloh, ‘Application of diffusion-edited and solvent suppression 1H-NMR to the direct analysis of markers in valerian-hop liquid herbal products’, Phytochemical Analysis, Vol 27(2): 100-106, first published online January 13, 2016, which has been published in final form at doi: 10.1002/pca.2603 This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving Copyright © 2016 John Wiley & Sons, Ltd.The rising trend to consume herbal products for the treatment and/or prevention of minor ailments together with their chemical and pharmacological complexity means there is an urgent need to develop new approaches to their quality and stability. This work looks at the application of one-dimensional diffusion-edited ¹H NMR spectroscopy (1D DOSY) and ¹H NMR with suppression of the ethanol and water signals to the characterization of quality and stability markers in multicomponent herbal medicines/food supplements. The experiments were performed with commercial tinctures of Valeriana officinalis L. (valerian), expired and non-expired, as well as its combination with Hummulus lupulus L. (hops), which is one of the most popular blends of relaxant herbs. These techniques did not require purification or evaporation of components for the qualitative analysis of the mixture, but only the addition of D2O and TSP. The best diagnostic signals were found at 7 ppm (H-11, valerenic acid), 4.2 ppm (H-1, hydroxyvalerenic acid) and 1.5-1.8 ppm (methyl groups in prenylated moieties, α-acids/prenylated flavones). This work concludes on the potential value of 1D DOSY ¹H NMR to provide additional assurance of quality in complex natural mixtures.Peer reviewe