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    Influenza vaccine effectiveness in Spain 2013/14: subtype-specific early estimates using the cycEVA study

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    Adjusted early estimates of the 2013/14 influenza vaccine effectiveness (VE) in Spain for all age groups was 35% (95% CI: -9 to 62), 33% (95% CI: -33 to 67) and 28% (95% CI: -33 to 61) against any influenza virus type, A(H1N1)pdm09 and A(H3N2) viruses, respectively. For the population targeted for vaccination, the adjusted VE was 44% (95% CI: -11 to 72), 36% (95% CI: -64 to 75) and 42% (95% CI: -29 to 74), respectively. These preliminary results in Spain suggest a suboptimal protective effect of the vaccine against circulating influenza viruses.This work was supported from the Influenza A(H1N1)pdm09 Programme of the Carlos III Institute of Health (GR09/0017 and PS12/00087). The GR09/0017 received additional funding from the World Health Organization Regional Office for Europe (WHO/Europe)/United States CDC (Centers for Disease Control and Prevention) and Epiconcept.S
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