Knowledge and practices of antibiotic prescription in Arkhangelsk, Russia. A cross-sectional survey among dentists and dental students

Aim: Considering the possible risk of continuing the negative trend of the development of resistant bacteria, and the association of high resistance to high use of antibiotics, therefore it is important to map the general knowledge among all healthcare professionals, including dentists, about antibiotic use practices. The aim of the study was, therefore, to reveal the knowledge among dentists, specialists and dental students regarding usage and prescription of antibiotics in Arkhangelsk, Russia. Material and methods: A questionnaire was distributed to dentists and last year dental student in the Arkhangelsk region in the span of one month in April of 2017. It was comprised of a total of 50 scoreable questions regarding knowledge and prescription of antibiotics in dentistry. Demographical questions were also collected. The scoreable questions were given values of one for correct answers and zero for incorrect. Mean scores were calculated as percentages and categorized as good (>80%), intermediate (60–80%), or poor (<60%). Results: 169 Participants fully filled out the questionnaire and were eligible to be analysed. The response rate was estimated to be around 22 percent. More than half of the participants were female (65.1%), and about half were in the age group 20 to 24 years of age (53.8%). The usage of Amoxicillin with Clavulanic acid was reported most frequently among the participants with over half checking it off (55.6%). Overall average knowledge was intermediate at 71.1%, with clinical signs having the poorest knowledge at 64.8% and the highest being non-clinical factors at 78.0%. Specialists working in the private sector had significantly better knowledge. Gender and work experience were not shown as statistically significant. Conclusion: The knowledge was shown to be intermediate, and generally consistent among groups and factors. Some outlier questions were answered mostly wrong or mostly correct, but the general consensus of the intermediate knowledge indicates that there is a need for more concentrated education and guidelines promoting restriction and correct usage of antibiotics

Estimating city-wide hourly bicycle flow using a hybrid LSTM MDN

Cycling can reduce greenhouse gas emissions and air pollution and increase public health. With this in mind, policy-makers in cities worldwide seek to improve the bicycle mode-share. However, they often struggle against the fear and the perceived riskiness of cycling. Efforts to increase the bicycle's mode-share involve many measures, one of them being the improvement of cycling safety. This requires the analysis of the factors surrounding accidents and the outcome. However, meaningful analysis of cycling safety requires accurate bicycle flow data that is generally sparse or not even available at a segment level. Therefore, safety engineers often rely on aggregated variables or calibration factors that fail to account for variations in the cycling traffic caused by external factors. This paper fills this gap by presenting a Deep Learning based approach, the Long Short-Term Memory Mixture Density Network (LSTMMDN), to estimate hourly bicycle flow in Copenhagen, conditional on weather, temporal and road conditions at the segment level. This method addresses the shortcomings in the calibration factor method and results in 66-77\% more accurate bicycle traffic estimates. To quantify the impact of more accurate bicycle traffic estimates in cycling safety analysis, we estimate bicycle crash risk models to evaluate bicycle crashes in Copenhagen. The models are identical except for the exposure variables being used. One model is estimated using the LSTMMDN estimates, one using the calibration-based estimates, and one using yearly mean traffic estimates. The results show that investing in more advanced methods for obtaining bicycle volume estimates can benefit the quality, mitigating efforts by improving safety analyses and other performance measures

The plight of camels eating plastic waste

Embargo until 23 October 2022Ecological impacts of plastic pollution are widespread, in all biomes and geographies. Here, we report the ingestion of anthropogenic waste, primarily plastic bags and rope by dromedary camels (Camelus dromedarius) in the United Arab Emirates (UAE), which has led to a regional mortality rate of 1%. We define the ingested waste as a polybezoar, a collection of tightly packed indigestible materials which can include plastics, ropes, other litter and salt deposits trapped in the stomach or digestive tract forming a large stone-like mass. In the Central Veterinary Research Laboratory (CVRL) in Dubai, UAE, of the more than 30,000 camels evaluated from the region since 2008, there have been 300 camels observed post-mortem with polybezoars in their stomach, from both camels in the CRVL or recovered from desiccated skeletons found in the desert. Here, we analyze a subset of five polybezoars ranging from 6.2 to 63.6 kg. Polybeozars lead to gastrointestinal blockages, sepsis from increased gut bacteria, dehydration and malnutrition. Due to high winds and the open desert environment, plastic bags and other film packaging escape open waste bins and landfills, traveling long distances; therefore we suggest improved waste management and alternative systems to package and deliver goods throughout the region.acceptedVersio

Putting 'vulnerable groups' at the centre of adaptation interventions by promoting transformative adaptation as a learning process

Report submitted to the Norwegian Agency for Development Cooperation (Norad)This report is a follow up and deepening of the working paper, “Climate change interventions and vulnerability reduction in developing countries: Challenges and leverage points for transformation”. In that backgrounder, we highlighted that many adaptation interventions inadvertently reinforce, redistribute or create new sources of vulnerability (Eriksen et al. 2021a), which is also reflected in the concept of ‘maladaptation’ that was recently foregrounded in the recent IPCC AR6 WGII Report (IPCC 2022). Maladaptation frequently stems from overly technical adaptation programming that is top-down and driven by outside objectives and knowledge. Instead, there is increasing recognition of adaptation as a socio-political process that addresses the root causes of the vulnerability of communities or segments of the population and, in so doing, builds the capacities of impacted populations and communities to engage climate challenges. This approach is termed ‘transformative adaptation’ and requires engagement with governance and institutional questions about whose values and perspectives are embraced within adaptation planning, and considering justice in these processes. This background paper highlights the kinds of practice that can help avoid maladaptive outcomes and promote transformative adaptation. Through case study examples of projects that - at least partially - embody aspects of a reflexive approach, the paper identifies ‘checklists’ of positive features to encourage and ‘red flags’ to be questioned or avoided in project proposal evaluation.NORA

Cleaning Up without Messing Up: Maximizing the Benefits of Plastic Clean-Up Technologies through New Regulatory Approaches

As the global plastics crisis grows, numerous technologies have been invented and implemented to recover plastic pollution from the environment. Although laudable, unregulated clean-up technologies may be inefficient and have unintended negative consequences on ecosystems, for example, through bycatch or removal of organic matter important for ecosystem functions. Despite these concerns, plastic clean-up technologies can play an important role in reducing litter in the environment. As the United Nations Environment Assembly is moving toward an international, legally binding treaty to address plastic pollution by 2024, the implementation of plastic clean-up technologies should be regulated to secure their net benefits and avoid unintended damages. Regulation can require environmental impact assessments and life cycle analysis to be conducted predeployment on a case-by-case basis to determine their effectiveness and impact and secure environmentally sound management. During operations catch-efficiency and bycatch of nonlitter items, as well as waste management of recovered litter, should be documented. Data collection for monitoring, research, and outreach to mitigate plastic pollution is recommended as added value of implementation of clean-up technologies.publishedVersio

Beyond technical fixes: climate solutions and the great derangement

Climate change research is at an impasse. The transformation of economies and everyday practices is more urgent, and yet appears ever more daunting as attempts at behaviour change, regulations, and global agreements confront material and social-political infrastructures that support the status quo. Effective action requires new ways of conceptualizing society, climate and environment and yet current research struggles to break free of established categories. In response, this contribution revisits important insights from the social sciences and humanities on the co-production of political economies, cultures, societies and biophysical relations and shows the possibilities for ontological pluralism to open up for new imaginations. Its intention is to help generate a different framing of socionatural change that goes beyond the current science-policy-behavioural change pathway. It puts forward several moments of inadvertent concealment in contemporary debates that stem directly from the way issues are framed and imagined in contemporary discourses. By placing values, normative commitments, and experiential and plural ways of knowing from around the world at the centre of climate knowledge, we confront climate change with contested politics and the everyday foundations of action rather than just data

Global assessment of marine plastic exposure risk for oceanic birds

Plastic pollution is distributed patchily around the world’s oceans. Likewise, marine organisms that are vulnerable to plastic ingestion or entanglement have uneven distributions. Understanding where wildlife encounters plastic is crucial for targeting research and mitigation. Oceanic seabirds, particularly petrels, frequently ingest plastic, are highly threatened, and cover vast distances during foraging and migration. However, the spatial overlap between petrels and plastics is poorly understood. Here we combine marine plastic density estimates with individual movement data for 7137 birds of 77 petrel species to estimate relative exposure risk. We identify high exposure risk areas in the Mediterranean and Black seas, and the northeast Pacific, northwest Pacific, South Atlantic and southwest Indian oceans. Plastic exposure risk varies greatly among species and populations, and between breeding and non-breeding seasons. Exposure risk is disproportionately high for Threatened species. Outside the Mediterranean and Black seas, exposure risk is highest in the high seas and Exclusive Economic Zones (EEZs) of the USA, Japan, and the UK. Birds generally had higher plastic exposure risk outside the EEZ of the country where they breed. We identify conservation and research priorities, and highlight that international collaboration is key to addressing the impacts of marine plastic on wide-ranging species

Internal and external information in error processing

<p>Abstract</p> <p>Background</p> <p>The use of self-generated and externally provided information in performance monitoring is reflected by the appearance of error-related and feedback-related negativities (ERN and FRN), respectively. Several authors proposed that ERN and FRN are supported by similar neural mechanisms residing in the anterior cingulate cortex (ACC) and the mesolimbic dopaminergic system. The present study is aimed to test the functional relationship between ERN and FRN. Using an Eriksen-Flanker task with a moving response deadline we tested 17 young healthy subjects. Subjects received feedback with respect to their response accuracy and response speed. To fulfill both requirements of the task, they had to press the correct button and had to respond in time to give a valid response.</p> <p>Results</p> <p>When performance monitoring based on self-generated information was sufficient to detect a criterion violation an ERN was released, while the subsequent feedback became redundant and therefore failed to trigger an FRN. In contrast, an FRN was released if the feedback contained information which was not available before and action monitoring processes based on self-generated information failed to detect an error.</p> <p>Conclusion</p> <p>The described pattern of results indicates a functional interrelationship of response and feedback related negativities in performance monitoring.</p

Adaptation interventions and their effect on vulnerability in developing countries: Help, hindrance or irrelevance?

This paper critically reviews the outcomes of internationally-funded interventions aimed at climate change adaptation and vulnerability reduction. It highlights how some interventions inadvertently reinforce, redistribute or create new sources of vulnerability. Four mechanisms drive these maladaptive outcomes: (i) shallow understanding of the vulnerability context; (ii) inequitable stakeholder participation in both design and implementation; (iii) a retrofitting of adaptation into existing development agendas; and (iv) a lack of critical engagement with how ‘adaptation success’ is defined. Emerging literature shows potential avenues for overcoming the current failure of adaptation interventions to reduce vulnerability: first, shifting the terms of engagement between adaptation practitioners and the local populations participating in adaptation interventions; and second, expanding the understanding of ‘local’ vulnerability to encompass global contexts and drivers of vulnerability. An important lesson from past adaptation interventions is that within current adaptation cum development paradigms, inequitable terms of engagement with ‘vulnerable’ populations are reproduced and the multi-scalar processes driving vulnerability remain largely ignored. In particular, instead of designing projects to change the practices of marginalised populations, learning processes within organisations and with marginalised populations must be placed at the centre of adaptation objectives. We pose the question of whether scholarship and practice need to take a post-adaptation turn akin to post-development, by seeking a pluralism of ideas about adaptation while critically interrogating how these ideas form part of the politics of adaptation and potentially the processes (re)producing vulnerability. We caution that unless the politics of framing and of scale are explicitly tackled, transformational interventions risk having even more adverse effects on marginalised populations than current adaptation

Global assessment of marine plastic exposure risk for oceanic birds

Plastic pollution is distributed patchily around the world’s oceans. Likewise, marine organisms that are vulnerable to plastic ingestion or entanglement have uneven distributions. Understanding where wildlife encounters plastic is crucial for targeting research and mitigation. Oceanic seabirds, particularly petrels, frequently ingest plastic, are highly threatened, and cover vast distances during foraging and migration. However, the spatial overlap between petrels and plastics is poorly understood. Here we combine marine plastic density estimates with individual movement data for 7137 birds of 77 petrel species to estimate relative exposure risk. We identify high exposure risk areas in the Mediterranean and Black seas, and the northeast Pacific, northwest Pacific, South Atlantic and southwest Indian oceans. Plastic exposure risk varies greatly among species and populations, and between breeding and nonbreeding seasons. Exposure risk is disproportionately high for Threatened species. Outside the Mediterranean and Black seas, exposure risk is highest in the high seas and Exclusive Economic Zones (EEZs) of the USA, Japan, and the UK. Birds generally had higher plastic exposure risk outside the EEZ of the country where they breed. We identify conservation and research priorities, and highlight that international collaboration is key to addressing the impacts of marine plastic on wide-ranging speciespublishedVersio