11,023 research outputs found
Building CMS Pixel Barrel Detectur Modules
For the barrel part of the CMS pixel tracker about 800 silicon pixel detector
modules are required. The modules are bump bonded, assembled and tested at the
Paul Scherrer Institute. This article describes the experience acquired during
the assembly of the first ~200 modules.Comment: 5 pages, 7 figures, Vertex200
A Development Environment for Visual Physics Analysis
The Visual Physics Analysis (VISPA) project integrates different aspects of
physics analyses into a graphical development environment. It addresses the
typical development cycle of (re-)designing, executing and verifying an
analysis. The project provides an extendable plug-in mechanism and includes
plug-ins for designing the analysis flow, for running the analysis on batch
systems, and for browsing the data content. The corresponding plug-ins are
based on an object-oriented toolkit for modular data analysis. We introduce the
main concepts of the project, describe the technical realization and
demonstrate the functionality in example applications
Universal deformation rings of modules for algebras of dihedral type of polynomial growth
Let k be an algebraically closed field, and let \Lambda\ be an algebra of
dihedral type of polynomial growth as classified by Erdmann and Skowro\'{n}ski.
We describe all finitely generated \Lambda-modules V whose stable endomorphism
rings are isomorphic to k and determine their universal deformation rings
R(\Lambda,V). We prove that only three isomorphism types occur for
R(\Lambda,V): k, k[[t]]/(t^2) and k[[t]].Comment: 11 pages, 2 figure
CMS Barrel Pixel Detector Overview
The pixel detector is the innermost tracking device of the CMS experiment at
the LHC. It is built from two independent sub devices, the pixel barrel and the
end disks. The barrel consists of three concentric layers around the beam pipe
with mean radii of 4.4, 7.3 and 10.2 cm. There are two end disks on each side
of the interaction point at 34.5 cm and 46.5 cm. This article gives an overview
of the pixel barrel detector, its mechanical support structure, electronics
components, services and its expected performance.Comment: Proceedings of Vertex06, 15th International Workshop on Vertex
Detector
Cooperative Cargo Transport by Several Molecular Motors
The transport of cargo particles which are pulled by several molecular motors
in a cooperative manner is studied theoretically. The transport properties
depend primarily on the maximal number, , of motor molecules that may pull
simultaneously on the cargo particle. Since each motor must unbind from the
filament after a finite number of steps but can also rebind to it again, the
actual number of pulling motors is not constant but varies with time between
zero and . An increase in the maximal number leads to a strong increase
of the average walking distance (or run length) of the cargo particle. If the
cargo is pulled by up to kinesin motors, e.g., the walking distance is
estimated to be micrometers which implies that seven or eight
kinesin molecules are sufficient to attain an average walking distance in the
centimeter range. If the cargo particle is pulled against an external load
force, this force is shared between the motors which provides a nontrivial
motor-motor coupling and a generic mechanism for nonlinear force-velocity
relationships. With increasing load force, the probability distribution of the
instantenous velocity is shifted towards smaller values, becomes broader, and
develops several peaks. Our theory is consistent with available experimental
data and makes quantitative predictions that are accessible to systematic in
vitro experiments.Comment: 24 pages, latex, 6 figures, includes Supporting Tex
Compact Frontend-Electronics and Bidirectional 3.3 Gbps Optical Datalink for Fast Proportional Chamber Readout
The 9600 channels of the multi-wire proportional chamber of the H1 experiment
at HERA have to be read out within 96 ns and made available to the trigger
system. The tight spatial conditions at the rear end flange require a compact
bidirectional readout electronics with minimal power consumption and dead
material.
A solution using 40 identical optical link modules, each transferring the
trigger information with a physical rate of 4 x 832 Mbps via optical fibers,
has been developed and commisioned. The analog pulses from the chamber can be
monitored and the synchronization to the global HERA clock signal is ensured.Comment: 13 pages, 10 figure
Edificação de um Construto Teórico sobre Processo de Formação de Estratégias de Gestão em Instituições de Ensino superior (IES) à luz dos pressupostos da Teoria da Complexidade
O presente trabalho tem por objetivo apresentar a elaboração de um construto teórico sobre processos de formação de estratégias de gestão em Instituições de Ensino Superior (IES), com base nos pressupostos da Teoria da Complexidade. Para edificação desse construto utilizou-se o referencial teórico sobre Universidades, Formação de Estratégias, Processos de Mudança, Teoria da Complexidade e Sistemas Adaptativos Complexos, articulado-os de tal forma que pudessem dar sustentação à proposta apresentada. A metodologia que orientou essa investigação teve por base a pesquisa de natureza bibliográfica, e assentou-se nas premissas do paradigma qualitativo e interpretativo, para dar conta de compreender a dinâmica do processo de formação de estratégia expressos em Planos de Gestão de Instituições de Ensino Superior e, assim, propor um construto de análise. A relevância desse construto está em permitir que se realize diagnósticos acerca do processo de formação de estratégias de gestão nessas instituições, com vistas à identificação se tal processo apresenta mais caracterÃsticas do modelo racional-formal, do modelo negociado ou do modelo em construção permanente, e em que grau incorpora as variáveis e os princÃpios apontados pela Teoria da Complexidade
L-selectin mediated leukocyte tethering in shear flow is controlled by multiple contacts and cytoskeletal anchorage facilitating fast rebinding events
L-selectin mediated tethers result in leukocyte rolling only above a
threshold in shear. Here we present biophysical modeling based on recently
published data from flow chamber experiments (Dwir et al., J. Cell Biol. 163:
649-659, 2003) which supports the interpretation that L-selectin mediated
tethers below the shear threshold correspond to single L-selectin carbohydrate
bonds dissociating on the time scale of milliseconds, whereas L-selectin
mediated tethers above the shear threshold are stabilized by multiple bonds and
fast rebinding of broken bonds, resulting in tether lifetimes on the timescale
of seconds. Our calculations for cluster dissociation suggest that
the single molecule rebinding rate is of the order of Hz. A similar
estimate results if increased tether dissociation for tail-truncated L-selectin
mutants above the shear threshold is modeled as diffusive escape of single
receptors from the rebinding region due to increased mobility. Using computer
simulations, we show that our model yields first order dissociation kinetics
and exponential dependence of tether dissociation rates on shear stress. Our
results suggest that multiple contacts, cytoskeletal anchorage of L-selectin
and local rebinding of ligand play important roles in L-selectin tether
stabilization and progression of tethers into persistent rolling on endothelial
surfaces.Comment: 9 pages, Revtex, 4 Postscript figures include
Dithienosilole-based all-conjugated block copolymers synthesized by a combination of quasiliving Kumada and Negishi catalyst-transfer polycondensations
Herein, we present a quasi-living Negishi-type catalyst-transfer polycondensation of a zinc–organic DTSbased monomer which provides an access to narrowly distributed poly(4,4-bis(2-ethylhexyl)dithieno[3,2-b:20,30-d]silole (PDTS) with controlled molecular weight. The synthesis of well-defined all-conjugated diblock copolymers containing a PDTS block was accomplished by a combination of Kumada and Negishi catalyst-transfer polycondensations (KCTP and NCTP, respectively). Particularly, it was shown that living P3HT chains obtained by KCTP of magnesium–organic thiophene-based monomer efficiently initiate NCTP of zinc–organic DTS-based monomer. The purity of the DTS-based monomer was found to be a crucial factor for achieving a clean chain-growth polymerization process. A combination of physico-chemical methods was used to prove the success of the block copolymerization
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