Effect of inspiratory pressure support on exercise performance in patients with chronic obstructive pulmonary disease

Title: Effect of inspiratory pressure support on exercise performance in patients with chronic obstructive pulmonary disease. Purpose: This study examined the effects of a non-invasive ventilator on submaximal and maximal exercise performance in patients with chronic obstructive pulmonary disease (COPD). Methods: Fourteen men (66.0 ± 7.4yr) and six women (59.0 ± 7.4yr) with a diagnosis of COPD, a forced expiratory volume! (FEVi) <40%, and the ability to tolerate 12 cmH20 of pressure on a non- invasive ventilator performed two maximal exercise tests on a cycle ergometer, with and without ventilatory assistance prior to exercise. Blood samples, respiratory metabolic measures, heart rate and rating of perceived exertion (RPE) were obtained throughout each exercise test. Results: Peak work rate (W), total exercise time, and respiratory rate were higher (p<0.05) when exercise was preceded by ventilatory support compared to no support. There was no difference in peak oxygen uptake (V02), carbon dioxide (VC02,), heart rate (HR), minute ventilation (VE), tidal volume (VT), blood lactate or RPE between the two experimental conditions. A total of 12 subjects completed at least 5 stages of the exercise protocol, and their physiological response during exercise with NIV and without NIV were compared. RPE was significantly lower during the first 3 min in the NIV condition than the no NIV condition. Circulating levels of blood lactate were lower (p<0.01) during stage 3 in the NIV than the than no NIV condition. There was no difference in RR, VT, HR, %HR, VE, V 0 2and %V02 between the two experimental conditions during sub maximal exercise. Conclusions: Application of non-invasive ventilatory support prior to exercise improves maximal exercise performance, but has no effect on cardio-metabolic response during submaximal exercise in patients with COPD

Letting Others Do Wrong

It is sometimes, but not always, permissible to let others do wrong. This paper is about why that is so

Meeting with U.S. Senate Candidate Lloyd Doggett

List of attendees meeting Geraldine Ferraro and Senate-candidate (and later Representative) Lloyd Doggett.https://ir.lawnet.fordham.edu/vice_presidential_campaign_materials_1984/1008/thumbnail.jp

"Food Ethics and Religion"

How does an engagement with religious traditions (broadly construed) illuminate and complicate the task of thinking through the ethics of eating? In this introduction, we survey some of the many food ethical issues that arise within various religious traditions and also consider some ethical positions that such traditions take on food. To say the least, we do not attempt to address all the ethical issues concerning food that arise in religious contexts, nor do we attempt to cover every tradition’s take on food. We look at just a few traditions and a few interesting writings on food ethics and religion: What do they say about the ethics of eating? Why do they say these things? Here we use the terms “food ethics” and “religion” ecumenically as big tents under which many importantly different sorts of things may be grouped. Among the wide range of food ethical issues we consider in this chapter, for example, are religious views about the ethics of keeping, hurting, and killing animals, killing plants, dominion over creation, wastefulness, purity, blessing, atonement, and the connection between food and character. We realize, moreover, that it might be a stretch to label some of the views engaged by selected readings in this chapter as “religious” on a stringent understanding of that term; Lisa Kemmerer’s “Indigenous Traditions,” for instance, addresses some views that are recognizably spiritual but perhaps not religious in a strict sense. We hope that our ecumenical usage of the term can bring these important traditions to bear on the discussion without reducing them to something they are not

Some effects of aerodynamic spoilers on wing flutter

The effects of deployment angle and size of symmetrically mounted upper-surface and lower-surface spoilers on the flutter characteristics of a simple, paddle-like, low-aspect-ratio, rectangular wing model that was tested at Mach number 0.80 in the Langley Transonic Dynamics Tunnel are presented. The results show that the flutter dynamic pressure is increased by increasing either spoiler deployment angle or spoiler size. For the configurations studied spoiler size was more effective than deployment angle in increasing the flutter dynamic pressure

On simple aerodynamic sensitivity derivatives for use in interdisciplinary optimization

Low-aspect-ratio and piston aerodynamic theories are reviewed as to their use in developing aerodynamic sensitivity derivatives for use in multidisciplinary optimization applications. The basic equations relating surface pressure (or lift and moment) to normal wash are given and discussed briefly for each theory. The general means for determining selected sensitivity derivatives are pointed out. In addition, some suggestions in very general terms are included as to sample problems for use in studying the process of using aerodynamic sensitivity derivatives in optimization studies

Aeroelastic instability stoppers for wind tunnel models

A mechanism for diverting the flow in a wind tunnel from the wing of a tested model is described. The wing is mounted on the wall of a tunnel. A diverter plate is pivotally mounted on the tunnel wall ahead of the model. An actuator fixed to the tunnel is pivotably connected to the diverter plate, by plunger. When the model is about to become unstable during the test the actuator moves the diverter plate from the tunnel wall to divert maintaining stable model conditions. The diverter plate is then retracted to enable normal flow

Subsonic flutter analysis addition to NASTRAN

A subsonic flutter analysis capability has been developed for NASTRAN, and a developmental version of the program has been installed on the CDC 6000 series digital computers at the Langley Research Center. The flutter analysis is of the modal type, uses doublet lattice unsteady aerodynamic forces, and solves the flutter equations by using the k-method. Surface and one-dimensional spline functions are used to transform from the aerodynamic degrees of freedom to the structural degrees of freedom. Some preliminary applications of the method to a beamlike wing, a platelike wing, and a platelike wing with a folded tip are compared with existing experimental and analytical results

Tackling out-of-pocket health care costs: a discussion paper

Growing out-of-pocket health care costs are creating barriers to essential care for many Australians and arguably leading to increased hospital costs. Over time they will undermine the universality of Medicare and widen health disparities in our community. Despite this, the Abbott Government is intent on increasing Australians\u27 individual health care costs, claiming variously that the health care budget is unsustainable,&nbsp;price signals are needed to reduce GP visits, budget deficits must be addressed and increased funding is needed for medical research. Regardless of the validity of the Government\u27s claims, it is clear that we need to improve the way in which we manage out-of-pocket costs within our health care system. The current financing mechansims and safety-net arrangements are inadequate to ensure that growing numbers of Australians with long-term medical conditions can manage their health care costs and afford the services they need. Given the compexity of Australia\u27s health care system, with funding and service delivery responsibilities split between different levels of government and the public and private sectors, this is a wicked problem to solve. There is no silver bullet and effective solutions are unlikely to be found through simple \u27add-ons\u27 to the currentfunding system. Effective solutions are likely to be multi-faceted and will require a potent mix of evidence, ideology, consultation and leadership to be successful. To kick-start the necesary analyses, debates and policy formulations, we have developed a discussion paper on out-of-pocket costs, focusing on Medicare-funded services. The paper sets out the parameters of the problem and canvasses some promising areas where solutions may be found. Our purpose is not to dictate future policy directions but to present&nbsp;the current evidence and to galvanise thought, expertise and engagement to address this issue of faireness and equity

Investment Management Code of Conduct for Endowments, Foundations, and Charitable Organizations

The Investment Management Code of Conduct for Endowments, Foundations, and Charitable Organizations represents best practice for the oversight of an entity's financial assets. Governing Body members should uphold the general principles of the Code in the management of the assets and the organization