Eficiencia de la inversión y desarrollo humano del proyecto de Desarrollo del proceso agroindustrial de la fruta tropical Maracuyás (Pasiflora edulis) realizado por el ministerio de economía familiar cooperativa, comunitaria y asociativa en los Municipios San Ramón, del departamento de Matagalpa; durante el segundo semestre del 2013

El presente trabajo está enfocado en la temática eficiencia de la inversión e impacto en el desarrollo humano del proyecto´´ proceso agroindustrial de las frutas tropicales maracuyá realizado por el Ministerio de Economía familiar comunitaria cooperativa y asociativa (MEFCCA) durante el segundo semestre del 2013 en el departamento de Matagalpa. En el trabajo investigativo se realizó un análisis a los productores beneficiados por el proyecto de proceso agroindustrial de maracuyás, además valorar las condiciones de desarrollo humano que se está ejecutando en algunas comunidades en los municipios de San Ramón, Sébaco y Tuma La Dalia; en las comunidades san Ramón, Guadalupe, Samulali, Yucul, Pueblo Viejo, Apatite, Departamento de Matagalpa,. En la investigación se analizaron elementos que se manifiestan e influyen de forma directa sobre la eficiencia de la inversión y desarrollo humano, por medio de la ejecución del Programa PROCAVAL, En la que se utilizaron técnicas dirigidas a los beneficiados del proyecto; socios activos de la Cooperativa COMANOR R.L, encuestas, entrevista, grupos focales y guía de observación. El proyecto se encuentra en fases ejecución de acuerdo a los objetivos propuesto del proyecto PROCACAL. Uno de los objetivo del proyecto es ayudar al fortalecimiento organizacional y seguimiento del proceso de agregación de valor y al mismo tiempo lograr la inserción exitosa al mercado nacional e internacional. El propósito del MEFCCA -PROCAVAL es que las familias en condiciones de pobreza del área rural, mejoren sus capacidades organizacionales como empresas, oportunidades de empleo, su capacidad de generar y diversificar los ingresos, a través de la inserción en cadenas de valor y mercados competitivo

The Neotropical species of Clistopyga (Hymenoptera, Ichneumonidae, Pimplinae). Part I: the C. chaconi species group, with the description of eleven new species

The New World Clistopyga chaconi species group is revised. Eleven species are described as new: C. amazonica sp. nov., C. cinnamoptera sp. nov., C. cuscoensis sp. nov., C. hayesiana sp. nov., C. melanoptera sp. nov., C. misionensis sp. nov., C. mocaguae sp. nov., C. orellanae sp. nov., C. porteri sp. nov., C. rondoniae sp. nov. and C. yabuquensis sp. nov. Additional morphological data are provided for the previously known species, C. caramba Castillo & Sääksjärvi and C. chaconi Gauld. An illustrated identification key to all species of the group is provided. The Clistopyga chaconi species group appears to be most diverse at the Andean and Amazonian interface in western South America.This study was partially supported by the projects “El valor de las Reservas Privadas en la conservación de la diversidad de insectos parasitoides” (Instituto Tecnológico Nacional de México, Code: 5554.15-P) and “Biodiversity and multitrophic interactions” (Kone Foundation, Finland)

Aplicación de método Marshall en el diseño de una mezcla asfáltica incorporando escoria de acero y caucho triturado

En el presente proyecto de investigación titulado “Aplicación de Método Marshall en el Diseño de una mezcla asfáltica incorporando escoria de acero y caucho triturado”, tiene como objetivo general analizar la influencia de escoria de acero y caucho triturado en el diseño de una mezcla asfáltica aplicando el método Marshal. En el cual las muestras que se llevaron a cabo fueron para un diseño convencional, diseños asfalticos modificado con escoria de acero al (3%, 6%, 9%, 12% y 15%) en remplazo del agregado grueso, diseños asfalticos modificado con caucho triturado al (0.20%, 0.40%, 0.60%, 0.80% y 1.00%) en remplazo del agregado fino, se determinó que el 6% de escoria de acero y el 0.80% de caucho triturado son los porcentajes óptimos y se realizó un nuevo diseño asfaltico que sería la combinación de los 2 productos y en cual se concluye que presentan una mejora en el índice de rigidez un 9.45%, en la estabilidad un 42.63% por lo tanto este tipo de mezcla contiene una mayor resistencia a la carga axial y a las deformaciones y en el flujo se tuvo un valor de 12.4 (0.01”) cumpliendo con la normativa. Se tiene un peso unitario de 2.306 gr/cm3, V.M.A 18.6%, vacíos de aire 3.9% y el cemento asfaltico tuvo un aumento del 3.45% con respecto al optimo del diseño convencional, todos los valores indican que cumplen con la normativa

Modelo comercial de una empresa de servicios de refurbished

El autor no autoriza la publicación de la tesis

Infected pancreatic necrosis: outcomes and clinical predictors of mortality. A post hoc analysis of the MANCTRA-1 international study

: The identification of high-risk patients in the early stages of infected pancreatic necrosis (IPN) is critical, because it could help the clinicians to adopt more effective management strategies. We conducted a post hoc analysis of the MANCTRA-1 international study to assess the association between clinical risk factors and mortality among adult patients with IPN. Univariable and multivariable logistic regression models were used to identify prognostic factors of mortality. We identified 247 consecutive patients with IPN hospitalised between January 2019 and December 2020. History of uncontrolled arterial hypertension (p = 0.032; 95% CI 1.135-15.882; aOR 4.245), qSOFA (p = 0.005; 95% CI 1.359-5.879; aOR 2.828), renal failure (p = 0.022; 95% CI 1.138-5.442; aOR 2.489), and haemodynamic failure (p = 0.018; 95% CI 1.184-5.978; aOR 2.661), were identified as independent predictors of mortality in IPN patients. Cholangitis (p = 0.003; 95% CI 1.598-9.930; aOR 3.983), abdominal compartment syndrome (p = 0.032; 95% CI 1.090-6.967; aOR 2.735), and gastrointestinal/intra-abdominal bleeding (p = 0.009; 95% CI 1.286-5.712; aOR 2.710) were independently associated with the risk of mortality. Upfront open surgical necrosectomy was strongly associated with the risk of mortality (p < 0.001; 95% CI 1.912-7.442; aOR 3.772), whereas endoscopic drainage of pancreatic necrosis (p = 0.018; 95% CI 0.138-0.834; aOR 0.339) and enteral nutrition (p = 0.003; 95% CI 0.143-0.716; aOR 0.320) were found as protective factors. Organ failure, acute cholangitis, and upfront open surgical necrosectomy were the most significant predictors of mortality. Our study confirmed that, even in a subgroup of particularly ill patients such as those with IPN, upfront open surgery should be avoided as much as possible. Study protocol registered in ClinicalTrials.Gov (I.D. Number NCT04747990)

Rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART): Study protocol for a randomized controlled trial

Background: Acute respiratory distress syndrome (ARDS) is associated with high in-hospital mortality. Alveolar recruitment followed by ventilation at optimal titrated PEEP may reduce ventilator-induced lung injury and improve oxygenation in patients with ARDS, but the effects on mortality and other clinical outcomes remain unknown. This article reports the rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART). Methods/Design: ART is a pragmatic, multicenter, randomized (concealed), controlled trial, which aims to determine if maximum stepwise alveolar recruitment associated with PEEP titration is able to increase 28-day survival in patients with ARDS compared to conventional treatment (ARDSNet strategy). We will enroll adult patients with ARDS of less than 72 h duration. The intervention group will receive an alveolar recruitment maneuver, with stepwise increases of PEEP achieving 45 cmH(2)O and peak pressure of 60 cmH2O, followed by ventilation with optimal PEEP titrated according to the static compliance of the respiratory system. In the control group, mechanical ventilation will follow a conventional protocol (ARDSNet). In both groups, we will use controlled volume mode with low tidal volumes (4 to 6 mL/kg of predicted body weight) and targeting plateau pressure <= 30 cmH2O. The primary outcome is 28-day survival, and the secondary outcomes are: length of ICU stay; length of hospital stay; pneumothorax requiring chest tube during first 7 days; barotrauma during first 7 days; mechanical ventilation-free days from days 1 to 28; ICU, in-hospital, and 6-month survival. ART is an event-guided trial planned to last until 520 events (deaths within 28 days) are observed. These events allow detection of a hazard ratio of 0.75, with 90% power and two-tailed type I error of 5%. All analysis will follow the intention-to-treat principle. Discussion: If the ART strategy with maximum recruitment and PEEP titration improves 28-day survival, this will represent a notable advance to the care of ARDS patients. Conversely, if the ART strategy is similar or inferior to the current evidence-based strategy (ARDSNet), this should also change current practice as many institutions routinely employ recruitment maneuvers and set PEEP levels according to some titration method.Hospital do Coracao (HCor) as part of the Program 'Hospitais de Excelencia a Servico do SUS (PROADI-SUS)'Brazilian Ministry of Healt

Search for gravitational-lensing signatures in the full third observing run of the LIGO-Virgo network

Gravitational lensing by massive objects along the line of sight to the source causes distortions of gravitational wave-signals; such distortions may reveal information about fundamental physics, cosmology and astrophysics. In this work, we have extended the search for lensing signatures to all binary black hole events from the third observing run of the LIGO--Virgo network. We search for repeated signals from strong lensing by 1) performing targeted searches for subthreshold signals, 2) calculating the degree of overlap amongst the intrinsic parameters and sky location of pairs of signals, 3) comparing the similarities of the spectrograms amongst pairs of signals, and 4) performing dual-signal Bayesian analysis that takes into account selection effects and astrophysical knowledge. We also search for distortions to the gravitational waveform caused by 1) frequency-independent phase shifts in strongly lensed images, and 2) frequency-dependent modulation of the amplitude and phase due to point masses. None of these searches yields significant evidence for lensing. Finally, we use the non-detection of gravitational-wave lensing to constrain the lensing rate based on the latest merger-rate estimates and the fraction of dark matter composed of compact objects

Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo

Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M>70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0<e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level

Ultralight vector dark matter search using data from the KAGRA O3GK run

Among the various candidates for dark matter (DM), ultralight vector DM can be probed by laser interferometric gravitational wave detectors through the measurement of oscillating length changes in the arm cavities. In this context, KAGRA has a unique feature due to differing compositions of its mirrors, enhancing the signal of vector DM in the length change in the auxiliary channels. Here we present the result of a search for U(1)B−L gauge boson DM using the KAGRA data from auxiliary length channels during the first joint observation run together with GEO600. By applying our search pipeline, which takes into account the stochastic nature of ultralight DM, upper bounds on the coupling strength between the U(1)B−L gauge boson and ordinary matter are obtained for a range of DM masses. While our constraints are less stringent than those derived from previous experiments, this study demonstrates the applicability of our method to the lower-mass vector DM search, which is made difficult in this measurement by the short observation time compared to the auto-correlation time scale of DM