26 research outputs found
Intentions to Use Virtual Worlds for Education
- Author
- Publication venue
- AIS Electronic Library (AISeL)
- Publication date
- 01/01/2009
- Field of study
Virtual worlds are becoming increasingly sophisticated, showing potential as an effective platform for a variety of collaborative activities, including learning. This study examines students’ intentions to use the virtual world Second Life (SL) for education, and explores factors associated with their intentions. Based on the Technology Acceptance Model (TAM) and extended factors, a research model is proposed. The model is tested through a survey administered to business school students who participated in Second Life in upper level MIS courses. Results suggest that perceived ease of use affects user’s intention to adopt SL through perceived usefulness. Computer self-efficacy and computer playfulness are also significant antecedents to perceived ease of use of virtual worlds. Implications for educators are presented
The Transformation of AT&T’s Enterprise Network Systems Group to Avaya: Enabling the Virtual Corporation through Reengineering and Enterprise Resource Planning
- Publication venue
- AIS Electronic Library (AISeL)
- Publication date
- 01/01/2003
- Field of study
This case discusses the management and control of a large enterprise-wide implementation of an ERP system while the business model and corporate culture were shaping and being shaped by that implementation. In 1995, the Enterprise Networks Systems business unit of AT&T faced a triad of problems caused by its legacy IT infrastructure, including the lack of timely, accurate financial and operating data, looming Y2K issues and systems capacity issues that were beginning to limit growth. A business plan for change was developed and approved. A project team was assembled to replace 25 years of legacy systems architecture (400+ systems) with a new enterprise systems architecture. The team was to act as change agent by supplanting a myriad of business processes and people practices that were seen as impediments to future growth and profitability. This case describes the design, development and deployment of one of the largest ERP implementations. The project required the implementation of standardized business processes and people practices for 30,000+ associates globally while minimizing the impacts on 1.3 million customers and on shareholders. Simultaneously, upper management set out on a strategy of creating a virtual business by outsourcing major business functions, including IT, Manufacturing and Distribution, and major parts of the sales and service operations. Other major events included the spin-offs of Lucent Technologies and Avaya
Determinants of intranet diffusion and infusion
- Publication venue
- Publication date
- Field of study
Commercial interest in Internet technology has grown tremendously in the last decade. Until now, little research has been devoted to examining the internal deployment of Internet technology. The present study focuses on the implementation process of intranets by examining factors associated with its diffusion and infusion in organizations. Findings suggest that earliness of adoption, top management support, and organizational size are positively associated with intranet diffusion. Intranet infusion is positively associated with earliness of adoption, top management support, and IT infrastructure flexibility, and these effects are mediated by intranet diffusion. Implications for management and suggestions for further research are discussed.Information technology Implementation Diffusion Infusion Innovation
An analysis of IS technical career paths and job satisfaction
- Author
- Publication venue
- 'Association for Computing Machinery (ACM)'
- Publication date
- Field of study
Patterns of interaction in adolescent romantic relationships: Distinct features and links to other close relationships
- Author
- Adams
- Ainsworth
- Andrews
- Bouchey
- Capaldi
- Capaldi
- Collins
- Collins
- Conger
- Connolly
- Davis
- Eder
- Elicker
- Furman
- Furman
- Furman
- Furman
- Furman
- Furman
- Furman
- Furman
- Giordano
- Giordano
- Hartup
- Julien
- Larson
- Larson
- Larson
- Larson
- Lauren B. Shomaker
- Laursen
- Laursen
- Laursen
- Laursen
- Lempers
- Maccoby
- Meehl
- Murray
- Olson
- Reis
- Richards
- Roisman
- Roth
- Tuval-Mashiach
- Werebe
- Wyndol Furman
- Zani
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Gummisubstanzen, Hemicellulosen, Pflanzenschleime, Pektinstoffe, Huminsubstanzen
- Author
- A Baumann
- A Hilger
- A Kreftling
- A Lemaire
- A Mayer
- A Meyer
- A Meyer
- A Meyer
- A Meyer
- A Müntz
- A Müntz
- A Müntz
- A Müntz
- A Raux
- A Raux
- A Tschirch
- A Tschirch
- A Tschirch
- A Tschirch
- A Tschirch
- A Tschirch
- A Ulander
- A Villiers
- A Villiers
- A Wigand
- A Wilhelmj
- AB Stevens
- Adametz
- Aderhold
- Aderhold
- Albert
- Allen
- Allen
- Allen
- Allen
- Allen
- Andrlik
- André
- André
- André
- André
- Aschan
- B Heinze
- B Heinze
- B Schröder
- B Schröder
- B Slowzow
- B Slowzow
- B Tacke
- B Tollens
- B Tollens
- Bach
- Bach
- Bader
- Baisch
- Baisch
- Baker
- Baker
- Bary De
- Battut
- Battut
- Battut
- Bau
- Bauer
- Bauer
- Bauer
- Bauer
- Bauer
- Bauer
- Bauer
- Bauer
- Bauer
- Bauer
- Bauer
- Bauer
- Bauer
- Bauer
- Baumann
- Beckerhinn
- Beeson
- Behrens
- Behrens
- Behrens
- Behrens
- Behrens
- Beijerinck
- Beijerinck
- Beijerinck
- Beijerinck
- Beijerinck
- Beijerinck
- Bemmelen Van
- Bemmelen Van
- Bemmelen Van
- Bemmelen Van
- Bemmelen Van
- Benedict
- Bente
- Bente
- Berichte
- Bert
- Berthelot
- Berthelot
- Berthelot
- Berthelot
- Berthelot
- Berthelot
- Berthelot
- Berthelot
- Bertrand
- Bertrand
- Bertrand
- Bertrand
- Berzelius
- Berzelius
- Berzelius
- Beulaygeie
- Bexelius
- Beyer
- Beyer
- Beyer
- Beyer
- Beyer
- Bitto
- Bittó
- Bodenbender
- Bodenberg
- Boekhout
- Boekhout
- Bokorny
- Boresch
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Bourquelot
- Brachin
- Braconnot
- Braconnot
- Brat
- Brown
- Brown
- Brown
- Browne
- Browne
- Brüning
- Buchner
- Burri
- Béchamp
- Béchamp
- Béchamp
- Béchamp
- Béchamp
- Béchamp
- Béchamp
- Béchamp
- Béchamp
- Béchamp
- C Bührer
- C Fischer
- C Mc
- C Montanari
- C Neubauer
- C Neubauer
- C Ravenna
- C Stanford
- C Stanford
- CA Browne
- CA Browne
- Castoro
- Cazeneuve
- Cazeneuve
- Chalmot
- Chalmot
- Chalmot
- Chalmot
- Chalmot
- Chalmot De
- Champenois
- Champenois
- Champenois
- Champenois
- Champenois
- Champion
- Chodnew
- Chodnew
- Chodnew
- Chodnew
- Chr Hansen
- Ciaessen
- Cienkowski
- CJ Koning
- Claasen
- Claus
- Clautriau
- Claësson
- Claësson
- Clermont
- Collignon
- Correns
- Councler
- Councler
- Councler
- Councler
- Councler
- Councler
- Councler
- Cramer
- Cremer
- Cremer
- Cremer
- Cremer
- Cremer
- Cremer
- Cremer
- Crié
- Crié
- Cross
- Cross
- Cross
- Cross
- Cross
- Cross
- Cross
- Croß
- Delacroix
- Delbrück
- Demel
- Demel
- Demel
- Demel
- Detmer
- Devaux
- Diguet
- Dojarenko
- Dojarenko
- Draggendorff
- Drenckmann
- Dubat
- Dumont
- Dumont
- Durin
- Délacroix
- Düll
- E Abderhalden
- E Bourquelot
- E Kißling
- E Lippmann v.
- E Lippmann v.
- E Lippmann v.
- E Lippmann v.
- E Liénard
- E Meininger
- E Meininger
- E Michelet
- E Payet
- E Schmidt
- E Schmidt
- E Schulze
- E Schulze
- E Schulze
- E Schulze
- E Schulze
- E Schulze
- E Schulze
- E Schulze
- E Schulze
- E Straßburger
- Eder
- Eder
- Eichhorn
- Eichhorn
- Eichhorn
- Eichhorn
- Ekenstein van
- Emmerling
- Emmerling
- Emmerling
- EO Lippmann v.
- Errera
- Errera
- Errera
- Errera
- Errera
- Errera
- Errera
- Errera
- Errera
- Errera
- Erémy
- Escombe
- Ewell
- F Beilstein
- F Czapek
- F Escombe
- F Lafar
- F Reinitzer
- F Reinitzer
- F Schardinger
- F Sestini
- F Sestini
- F Tobler
- Faber
- Fels
- Fels
- Fels
- Felsko
- Feltz
- Feltz
- Fischer
- Fischer
- Fittbogen
- FL Lewton
- Flechsig
- Flint
- Flückiger
- Formenti
- Forti
- Frank
- Fremy
- Fremy
- Fremy
- Fribes
- Frischmuth
- Frischmuth
- Frischmuth
- Fränkel
- Frémy
- Frémy
- Fudakowski
- Fudakowsky
- FW Pavy
- FW Pavy
- G Lange
- G Seillière
- G Smith
- G Smith
- G Tomann
- G Vée
- Gans
- Gans
- Gans
- Garros
- Garros
- Garros
- Gawrilow
- Gayaud
- Gelis
- Gilson
- Gilson
- Girard
- Giraud
- Giraud
- Gladstone
- Glaser
- Glaser
- Goldschmidt
- Goret
- Goret
- Gorgeu
- Gorgeu
- Gostling
- Gottlieb
- Gottlieb
- Graefe
- Grafe
- Graham
- Greenish
- Greenish
- Greenish
- Gregory
- Greig
- Greig-Smith
- Greig-Smith
- Greig-Smith
- Grote
- Grote
- Grünhut
- Grütter
- Grüß
- Grüß
- Grüß
- Grüß
- Guichard
- Guichard
- Guignard
- Guèrin-Varrey
- Guérin-Varry
- Guérin-Varry
- Guérin-Varry
- Guérin-Varry
- Götze
- Götze
- Günsberg
- Günther
- Günther
- H Bierry
- H Euler
- H Feilitzen v.
- H Jumelle
- H Laer van
- H Ludwig
- H Runne
- H Walliczek
- H Will
- Haas
- Haedicke
- Halbey
- Halbey
- Hammarsten
- Hanriot
- Happ
- Harden
- Harden
- Harley
- Harley
- Hart
- Hart
- Hartwich
- Hartwich
- Hauers
- Hauers
- Hauers
- Hauers
- Hauers
- Henneberg
- Hermann
- Hermann
- Hermann
- Hermann
- Hermann
- Herzfeld
- Herzfeld
- Herzfeld
- Herzfeld
- Herzfeld
- Herzfeld
- Herzfeld
- Herzfeld
- Herzfeld
- Herzfeld
- Herzfeld
- Herzfeld
- Herzfeld
- Hessenland
- Hessenland
- Hessenland
- Hessenland
- Hilger
- Hilger
- Hilger
- Hilger
- Hilger
- Hilger
- Hilger
- Hiltner
- Hirschsohn
- Hirschsohn
- Hirschsohn
- Hirschsohn
- Hirschsohn
- Hirschsohn
- Hlasiwetz
- Hlasiwetz
- Hlasiwetz
- Hoffmeister
- Hoffmeister
- Hoffmeister
- Hoffmeister
- Hohenadel
- Hohl
- Hoppe — Seyler
- Hoppe-Seyler
- Hoppe-Seyler
- Hoppe-Seyler
- Hoppe-Seyler
- Hotter
- Hébert
- Hébert
- Hérissey
- Hérissey
- Hérissey
- Hérissey
- Höhnel
- Höhnel v.
- Hönig
- Hönig
- Ihl
- Ihl
- Ishii
- J Effront
- J Effront
- J Effront
- J Grüß
- J Grüß
- J König
- J König
- J Moeller
- J Möller
- J Müller
- J Müller
- J Pohl
- J Sebelien
- J Seynes de
- J Seynes de
- J Vamwakas
- J Wiesner
- J Wiesner
- Javillier
- Javillier
- Javillier
- Javillier
- Javillier
- Javillier
- Jensen
- Jodlbauer
- Johnson
- Jubert
- Jubert
- Jäger
- K Boresch
- K Daalen van
- K Dieterich
- Kamerling
- Kellner
- Kellner
- Kerp
- Kiliani
- Kiliani
- Kiliani
- Kiliani
- Kiliani
- Kiliani
- Kiliani
- Kimoto
- Kircher
- Kirchner
- Kirchner
- Klason
- Klebs
- Klebs
- Klebs
- Knitl
- Koch
- Koch
- Koch
- Koch
- Koch
- Kolb
- Kolb
- Kostytscheff
- Kramer
- Kramer
- Kramer
- Kramer
- Kramer
- Kraus
- Kroeker
- Kruskal
- Kuthe
- Kuthe
- Köhler
- Köhler
- Köhler
- Kölle
- König
- König
- König
- L Hauman
- L Ishii
- L Mangin
- L Mangin
- L Mangin
- L Mangin
- L Sablon du
- L Sablon du
- L Scoville
- L Tollens
- Laer Van
- Lafar
- Landw
- Landw
- Landw
- Landwehr
- Landwehr
- Landwehr
- Landwehr
- Landwehr
- Landwehr
- Landwehr
- Landwehr
- Landwehr
- Landwehr
- Landwehr
- Landwehr
- Landwehr
- Landwehr
- Landwehr
- Landwehr
- Lauren
- Laurent
- Laurent
- Laxa
- Laxa
- Lefort
- Leichmann
- Levites
- Liebermann
- Liebermann
- Liebermann
- Liebig
- Liesenberg
- Liesenberg
- Liesenberg
- Lindet
- Lindet
- Lindet
- Lindet
- Lindet
- Lindet
- Lindsey
- Lindsey
- Lindsey
- Lindsey
- Lineburger
- Lineburger
- Lintner
- Lintner
- Lintner
- Lippmann
- Lippmann
- Lippmann
- Lippmann
- Lippmann
- Lippmann
- Lippniann
- Lippniann
- Liénard
- Liénard
- Loew
- Loewu
- Lutz
- Léger
- M Conrad
- M Conrad
- M Fleischer
- M Jodlbauer
- M Tsukamoto
- Maassen
- Maassen
- Macquenne
- Malaguti
- Malaguti
- Malkomesius
- Malkomesius
- Malkomesius
- Mangin
- Mangin
- Mangin
- Mangin
- Mangin
- Mangin
- Mann
- Masing
- Masing
- Maumené
- Maumené
- Maumené
- Maxwell
- Maxwell
- Maxwell
- Maxwell
- Maxwell
- Mayer
- Mayer
- Meigen
- Meigen
- Mendes
- Merlis
- Michaud
- Michaud
- Miklauz
- Millon
- Millot
- Mme
- Mme
- Mme
- Montanari
- Moore
- Mulder
- Mulder
- Mulder
- Mulder
- Mulder
- Mulder
- Munk
- Munsche
- Musculus
- Mutschler
- Müntz
- Müntz
- Müther
- N Castoro
- N Castoro
- N Castoro
- N Castoro
- NA Tschirchin
- Nadelmann
- Nannes
- Nestler
- Nestler
- Neubauer
- Neubauer
- Neubauer
- Neubauer
- Neubauer
- Neubauer
- Neuberg
- Nikitinsky
- Nilson
- Nivière
- Nivière
- Nägeli
- Nägeli
- O Boudouard
- O Boudouard
- O Emmerling
- O Emmerling
- O Folin
- O Fromm
- O Lippmann v.
- O Richter
- O Ruff
- Okamura
- Omelianski
- Orth
- Osborne
- Oshima
- Oshima
- Oudemans
- O’Sullivan
- O’Sullivan
- O’Sullivan
- O’Sullivan
- O’Sullivan
- O’Sullivan
- O’Sullivan
- O’Sullivan
- O’Sullivan
- O’Sullivan
- O’Sullivan
- O’Sullivan
- O’Sullivan
- O’Sullivan
- P Carles
- P Lemeland
- P Lindner
- P Lindner
- P Lémeland
- P Paulitschke
- P Sorauer
- P Sorauer
- Panzer
- Panzer
- Panzer
- Parkin
- Pasteur
- Payen
- Peckolt
- Peters
- Petit
- Pitoy
- Plzák Berichte d
- Pohl
- Pohl
- Pohl
- Pohl
- Pohl
- Polášek
- Popoff
- Pouchet
- Pouchet
- Pouchet
- Poumarède
- Poumarède
- Poumarède
- Praktik
- Prazmovski
- Prescher
- Prinsen — Geerlings
- Prochazka
- Prochazka
- Péligot
- Péligot
- Péligot
- Péligot
- Péligot
- Péligot
- R Albert
- R Albert
- R Bauer
- R Braun
- R Greig-Smith
- R Hefelmann
- R Lemeland
- R Meißner
- R Meißner
- R Otto
- R Zsigmondy
- R Zsigmondy
- RA Robertson
- Rant
- Ray man
- Reichardt
- Reichardt
- Reichardt
- Reichardt
- Reichardt
- Reichardt
- Reiehardt
- Reinitzer
- Reinitzer
- Reinitzer
- Reiß
- Reiß
- Reiß
- Renault
- RH Christensen
- Rideal
- Rietschel
- Ritthausen
- Ritthausen
- Ritthausen
- Ritthausen
- Robertson
- Roeser
- Roger
- Rolland
- Rolland
- Rümpler
- S Ivanow
- S Ivanow
- Saare
- Sabor
- Sachsse
- Salkowski
- Salkowski
- Salkowski
- Salkowski
- Salkowski
- Salkowski
- Salkowski
- Salkowski
- Salkowski
- Salkowski
- Salkowski
- Salkowski
- Samoggia
- Sandersleben
- Sawamura
- Sawamura
- Sawamura
- Sawamura
- Schade
- Schardinger
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Scheibler
- Schellenberg
- Schellenberg
- Schellenberg
- Schermbeck van
- Schermbeck van
- Schermbeck Van
- Schmidt
- Schmidt-Mühlheim
- Schmidt-Mühlheim
- Schmöger
- Schmöger
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schulze
- Schweinfurth
- Schützenberger
- Schützenberger
- Schützenberger
- Schützenberger
- Schützenberger
- Schützenberger
- Schützenberger
- Schützenberger
- Sebor
- Sebor
- Sebor
- Seiler
- Seiler
- Seligmann
- Sestini
- Sestini
- Sestini
- Sestini
- Sestini
- Sestini
- Sestini
- Sestini
- Sestini
- Sherman
- Sherman
- Sickel
- Sievers
- Skerst
- Slowtzoff
- Slowtzoff
- Smith
- Sollied
- Sostegni
- Sostegni
- Sostegni
- Staedeler
- Standford
- Steiger
- Steiger
- Steiger
- Stenberg
- Stenberg
- Stevens
- Stevens
- Stohmann
- Stohmannu
- Stoklasa
- Stoklasa
- Stoklasa
- Stoklasa
- Stoklasa
- Stoklasa
- Stoklasa
- Stone
- Stone
- Stone
- Stone
- Stone
- Stone
- Stone
- Stone
- Stone
- Stone
- Stone
- Stone
- Storer
- Stremme
- Strohecker
- Strohmer
- Strohmer
- Struve
- Stüde
- Suringar
- T Lippmann
- T Saiki
- Tacke
- Tacke
- Tanret
- Terreil
- Thierfelder
- Thomsen
- Thomson
- Thomson
- Thomson
- Tieghem Van
- Tieghem Van
- Tobler
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens
- Tollens u. Oshima Berichte d
- Tolléns
- Treffner
- Tromp de Haas
- Tromp de Haas
- Tschirch
- Tschirch
- Tschirch
- Tschirch
- Tschirch
- Tschirch
- Tschirch
- Tschirch
- Tschirch
- Tschirch
- Tschirch
- Tsuji
- Tsuji
- Tunmann
- Udranzky
- Udranzky
- Ullik
- Ullik
- Ullik
- Ullik
- V Harley
- VanTieghem
- VanTieghem
- Vogtherr
- Voit
- Voley-Boucher
- Voswinkel
- Votocek
- Votocek
- Votocek
- Votocek
- Votoček
- Votoček
- Votoček
- Votoček
- W Henneberg
- W Istseherekow
- W Meigen
- W Meigen
- W Pfeffer
- W Ruhland
- W Tollens
- W Tromp de Haas
- W Tromp de Haas
- Wachtel
- Warmbold
- Websky
- Wegner
- Wegner
- Weigmann
- Weisberg
- Weisberg
- Weisberg
- Weiser
- Weiser
- Weiser
- Weiske
- Welbel
- Wende
- Weydemann
- Wheeler
- Wheeler
- Wheeler
- Wheeler
- Wheeler
- Wheeler
- Wheeler
- Wheeler
- Wheeler
- Wheeler
- Widtsoe
- Widtsoe
- Wieler
- Wigand
- Will
- Will
- Will
- Williams
- Windisch
- Winogradsky
- Winogradsky
- Winter
- Winter
- Winter
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Winterstein
- Wisselingh Van
- Wisselingh Van
- Wohl
- Wohl
- Wohl
- Wohl
- Wohl
- Wohl
- WP Cooper
- Wroblewski
- Wroblewski
- Wroblewski
- Wroblewski
- Wroblewski
- Y Kinoshita
- Zeisel
- Zopf
- Zopf
- Zopf
- Zulkowsky
- Zuzuki
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1911
- Field of study
Risk of COVID-19 after natural infection or vaccinationResearch in context
- Author
- A. Lina Rosengren
- Abram Burgher
- Adam B. Brosz
- Adam Rosen
- Adam Schwartz
- Adriana Sordo Duran
- Adrienna Marquez
- Adrienne E. Shapiro
- Aeiress Duhart
- Afsoon Roberts
- Albert Liu
- Alejandro Hoberman
- Alejandro Quintín Barrat Hernández
- Alex Greninger
- Alexander Clark
- Alfredo Gilberto Guerreros Benavides
- Alice McGarry
- Alicia Arrazcaeta
- Alisha Lutat
- Alison Bondell
- Alison Pellecchia
- Allie Oplinger
- Allison Green
- Allison O'Brien
- Alpa Patel
- Alyssa-Kay Peay
- Amanda Horn
- Amanda Lilienthal
- Amanda Occhino
- Amanda Philyaw
- Amaran Moodley
- Amber Grant
- Amber Stanford
- Amesika Nyaku
- Amie Shannon
- Amina Z. Haggag
- Amit Paliwal
- Amy Caldwell
- Amy Chamberlain
- Amy Dye
- Amy Falk
- Amy Kelley
- Amy Medina
- Amy Potts
- Amy Salzl
- Amy Sherman
- Amy Starr
- Amy Thompson
- Andrea Berry
- Andrea Clement
- Andrea Wendrow
- Andrea Zimmer
- Andres Bran
- Andres Camacho-Gonzalez
- Andrew Lauria
- Andrew McConnell
- Andrew McWilliams
- Anelgine C. Yoon
- Angela Lee
- Angela R. Branche
- Angelica Kottkamp
- Angella Webb
- Ann M. Milliken
- Ann R. Falsey
- Anna S. Lok
- Anna Wald
- Anne Marit de Groot
- Anne-Marie Rick
- Annette R. Bennett
- Annie Ciambruschini
- Annie Luetkemeyer
- Anthony Kim
- Anum Abbas
- Anyela Lara
- April Pixler
- Ariana C. Stanton
- Arthur L. Zemanek
- Asha Inniss
- Ashley Kennedy
- Ashley Perez
- Ashley Warden
- Asif Noor
- Atoya Adams
- Aurelio Cruz-Valdez
- Austin Chan
- Austin Swanson
- Ayanna Walters
- Ayoade Avworo
- Bailey Jordan
- Barbara Corral
- Barbara Rizzardi
- Barbara Rizzardi
- Barbara S. Taylor
- Barry S. Zingman
- Barton G. Williams
- Beatriz Grinsztejn
- Becky Martinez
- Ben Ladner
- Benjamin Eckhardt
- Benjamin J. Luft
- Bernard Grunstra
- Beth Safirstein
- Bethanie Wilkinson
- Beverly E. Sha
- Beverly Ewing
- Bindu Balani
- Blanca Gomez
- Bo Shopsin
- Boerries Brandenburg
- Brandie Taylor
- Brandon J. Essink
- Brandy Ball
- Breanz Watkins
- Brenda Dorcely
- Brendan Levy
- Brett Gray
- Brett Leav
- Brian D.W. Chow
- Brit Sovic
- Brittany Feijoo
- Brittany Stewart
- Bruce C. Gebhardt
- Bruce G. Rankin
- Bruce McClenathan
- Bruno Valenti
- Bryan Gordon
- C. Mary Healy
- Caitlin J. Guiney
- Caitlin Moran
- Candace Smith
- Candice Montros
- Carina A. Rodriguez
- Carl Fichtenbaum
- Carl P. Griffin
- Carlos A. Fierro
- Carlos del Rio
- Carlos Lopez
- Carlos Malvestutto
- Carmel B. Dyer
- Carmen A. Paez
- Carmen Amador
- Carmen D. Zorrilla
- Carmen Medina
- Carol Ann Linebarger
- Carol Kauffman
- Carol L. Mitchell
- Carolene Stephenson
- Caroline Greene
- Carolyn Scatamacchia
- Carolyn Tran
- Carrie Johnston
- Carrie Sopher
- Catherine A. Bunce
- Catherine Mary Healy
- Catherine Q. Gular
- Cathy Laflan
- Cecilia McKeown-Bragas
- Celia Gonzalez
- Celia Maxwell
- Charles Harper
- Charles M. Fogarty
- Charlotte-Paige Rolle
- Charnell Cromer
- Chelsea Miles
- Chelsie Nutsch
- Chelsie Nutsch
- Chen S. Tan
- Chenchen Yu
- Cheryl Nuss
- Cheryl Young
- Chimeremma Nnadi
- Chinar Desai
- Christian Tomaszewski
- Christina A. Rostad
- Christina Bacher
- Christina Kennelly
- Christine Akamine
- Christine B. Turley
- Christine Hull
- Christine Wilson
- Christopher Carpenter
- Christopher Dedon
- Christopher Galloway
- Christopher Matich
- Christy Schmeck
- Christy Sweet
- Clarence B. Creech II
- Clarisse Baudelaire
- Claudia De La Matta Rodriguez
- Claudia Espinosa
- Claudio Nuñez Lagos
- Clint C. Guillory
- Clint Wilson
- Codi M. Anthony
- Colleen F. Kelley
- Colleen Jacobsen
- Connie Moya
- Cora Sonnier
- Corey G. Anderson
- Corey M. Chen
- Cornell Calinescu
- Corrina Pavetto
- Cortney Burch
- Cory J. Huffine
- Craig Dietz
- Cristina Cicogna
- Crystal Rowell
- Cynthia Becher Strout
- Cynthia Brown
- Cynthia Bueno
- Cynthia L. Gay
- Cynthia L. Monaco
- Cynthia Montano-Pereira
- Cyrus Hoseyni
- Dakotah C. Lane
- Dalia Tovar
- Daniel Duncanson
- Daniel Hoft
- Daniel Kaul
- Daniel S. Graciaa
- Daniel T. Lawler
- Daniela Pineda Méndez
- Danielle Raley
- Danny Sugimoto
- Danyel Johnson
- Darlene Bartilucci
- David B. Musante
- David Beckmann
- David Browder
- David Dellaero
- David Fitz-Patrick
- David Halpert
- David I. Bernstein
- David J. Diemert
- David J. Ensz
- David Kline
- David L. Fried
- David Metzger
- David Pampe
- David Pitrak
- David R. Andes
- David Rosenberg
- David Tatelbaum
- David Wohl
- Dawn Furey
- Dawn Robison
- Dean Follmann
- Dean M. Boswell
- Deanna Cooper
- Debora Dunbar
- Deborah A. Theodore
- Deborah Murray
- Debra B. Schroeck
- Delia Bullock
- Denis Tarakjian
- Denise Casey
- Denise Roadman
- Denise Sample
- Denisse Alejandra González Estrada
- Derek Lewis
- Derek M. Smith
- Destiny S. Heinzig-Cartwright
- Diana Badillo
- Diana F. Florescu
- Diana Vegas
- Dianca Sierra
- Diane H. Johnson
- Dilek Ince
- Dima Dandachi
- Dirk Heerwegh
- Dolores Rijos
- Donald M. Brandon
- Donald Quinn
- Donna Percy
- Doris Franco-Vitteri
- Douglas S. Denham
- E. Javier Pretell Alva
- Edgar Garcia
- Edith Swann
- Eduardo Gabriel Vázquez Saldaña
- Edward C. Jones-López
- Edward E. Walsh
- Edward Ellerbeck
- Edward M. Tavel Jr.
- Elham Ghadishah
- Elie Gharib
- Elisa Swieboda
- Elissa Malkin
- Elizabeth Barranco-Santana
- Elizabeth Bennett
- Elizabeth Bruce
- Elizabeth Danford
- Elizabeth Duke
- Elizabeth E. Robison
- Elizabeth Everette
- Elizabeth Formentini
- Elizabeth Hammershaimb
- Elizabeth Parker
- Elizabeth Secord
- Ellie Carmody
- Elliot DeHaan
- Elwaleed Elnagar
- Emily Degan
- Emily Oppenheim
- Emma Bainbridge
- Emmanuel B. Walter
- Eneyda Giuvanela Llerena Zegarra
- Enrique Ocaña
- Eric A. Meyerowitz
- Eric Bravo
- Eric McGrath
- Eric Miller
- Erica Herc
- Erica Johnson
- Erica Osmundsen
- Erica Sanchez
- Erika A. Cutz
- Erika Mendoza
- Erin A. Goecker
- Erin Cooksey
- Erin Coston
- Ernesto Delgado
- Esther L. Harmon
- Esther S. Huffine
- Evan C. Ewers
- Evan J. Anderson
- Evelyn Hall
- Evelyn Lomasney
- Evelyn Quevedo
- Fan Yang
- Farah Irani
- Farhan Siddiqui
- Fernanda Morales
- Fernando L. Merino
- Filip Dubovsky
- Flora Castellino
- Florence Momplaisir
- Florida Aristy
- Frances Downing
- Frank James
- Frank S. Eder
- Frank Struyf
- Fred E. Newton
- Frederick Raiser III
- Fredric Santiago
- Gail Broder
- Gary Albert
- Gary Headden
- Gary Horwith
- Gary Luckasen
- Gary Simon
- Gayle D. Hennekes
- Genevieve Beninati
- Genevieve Iwuala
- George H. Bauer Jr.
- George H. Freeman
- Georgette Ebuh
- Georgettea Geuss
- Gerald Kelty
- Germán Áñez
- Getahun Abate
- Gina Rivero
- Glenda E. Gray
- Glenn Wortman
- Gowdhami Mohan
- Grant Ellsworth
- Grant Geiger
- Greg Hachigian
- Greg Wilson
- Gregg H. Lucksinger
- Gregory C. Utz
- Gregory Holt
- Gregory J. Feldman
- Gregory M. Glenn
- Gregory M. Gottschlich
- Griet Van Roey
- Guillermo Miguel Ruiz-Palacios
- Gysella Muniz
- Hala Webster
- Hana M. El Sahly
- Hanh Chu
- Hanh Chu
- Hannah Catan
- Hannah Harrington
- Hannah Nevarez
- Haoua Dunbar
- Hayes Williams
- Heather Rattenbury-Shaw
- Henry Peralta
- Hilario Alvarado
- Hillary Dunlevy
- Holli Hamilton
- Holly E. Janes
- Hong V. Tieu
- Horacio Marafioti
- Howard I. Schwartz
- Howard Schwartz
- Hussain Malbari
- Huub G. Gelderblom
- Hyman Scott
- Ian De Proost
- Ian Frank
- Ian Hirsch
- Iksung Cho
- Ilse Van Dromme
- Insiya Valika
- Irene Graham
- Irene McKnight
- Iris García
- Isaac Thomsen
- Isabel Pereira
- Issac Pena-Renteria
- Jack Stapleton
- Jacob Coleman
- Jacqueline Miller
- Jacqueline Muenzner
- Jaleh Ostovar
- Jaleh Ostovar
- Jalima Quintero
- James Andersen
- James Fry
- James G. Kublin
- James H. Conway
- James Longe
- James Lovell
- James N. Goldenberg
- James Peacock
- James Ramsey
- James T. Peterson
- James W. Hurst
- James Walker
- James Zhou
- Jamie Ackerman
- Jamshid Saleh
- Jan Patterson
- Janet Garvey
- Janet Hill
- Janet Mendez
- Janet Otto
- Janeth Pacheco-Flores
- Janice Suyehira
- Janine Maenza
- Jarek Juraszek
- Jason F. Okulicz
- Jason Milligan
- Jay Meyer
- Jayasree Krishnankutty
- Jeanne Blevins
- Jeb Andrews
- Jeff Kingsley
- Jeffrey A. Henderson
- Jeffrey Adelglass
- Jeffrey Dugas Sr.
- Jeffrey Klein
- Jeffrey M. Jacobson
- Jeffrey Meier
- Jeffrey Rosen
- Jeffrey S. Overcash
- Jeffrey Thessing
- Jeffry Jacqmein
- Jenina Garcia
- Jennie Johnson
- Jennifer A. Johnson
- Jennifer A. Whitaker
- Jennifer Bashour
- Jennifer Berry
- Jennifer Chang
- Jennifer Foley
- Jennifer Knishinsky
- Jennifer Knowles
- Jennifer L. Dong
- Jennifer McCarter
- Jennifer Petts
- Jennifer Schwartz
- Jennifer Winbigler
- Jenny Hendriks
- Jerald Sadoff
- Jeremy Ackermann
- Jeremy Brown
- Jerome Custers
- Jerome G. Naifeh
- Jesse L. Clark
- Jessica E. Justman
- Jessica G. Andriesen
- Jessica Heimonen
- Jessica Ibarra
- Jessica L. Ansel
- Jessica L. Lee
- Jessica L. Weidler
- Jessica M. Mena
- Jessica Ortega
- Jessica Rodriguez
- Jessica Stahl
- Jewel J. White
- Jill Blumenthal
- Jill Kessler
- Jill York
- Jim Callis
- Joan Rothenberg
- Joanne L. Billings
- Jocelyn Zuleica Olmos Vega
- Jodi Meck
- Joel Solis
- Johan Vingerhoets
- John A. Kirby
- John J. Treanor
- John Johnson
- John Lucaj
- John M. Hill
- John Mascola
- John S. Kizer
- John Sanders
- John W. McGettigan Jr.
- John Witbeck
- Jon F. Dedon
- Jon Finley
- Jonathan Staben
- Jonlyn McGettigan
- Jordan Coslet
- Jordan L. Whatley
- Jorge A. Benitez
- Jorge A. Chacón
- Jorge Caso
- Jorge F. Méndez Galván
- Jose A. Bazan
- Jose C. Mancilla
- Jose Castillo Mancilla
- Jose Gonzales-Zamora
- Joseph Bocchini
- Joseph Boscia
- Joseph D. Davis
- Joseph Eron Jr.
- Joseph Grillo
- Joseph J. Eron
- Joseph L. Newberg
- Joseph P. Connor
- Joseph Yusin
- Joshua Rindt
- José O. Alemán
- Joy Nelson
- Juan J. Rivera
- Juan Luis Yrivarren Giorza
- Juan P. Torres
- Juan V. Guanira-Carranza
- Juana R. Pavie
- Juana Rivera
- Judith Borger
- Judith Brady
- Judith L. Kirstein
- Judith Martin
- Judy Pi
- Julia Hutter
- Julia Lord
- Julian A. Torres
- Julie A. Ake
- Julie Hussey
- Julie Ledgerwood
- Julie White
- Julio Nasim
- Justin Singletary
- Kacie Sales
- Kami Kim
- Karen Deutsch
- Karen Freudemann
- Karen L. Kotloff
- Karen Ruperto
- Karen Sofia Vega Orozco
- Karen Tashima
- Karin Choquette
- Karina Cano Martínez
- Karl M. Thompson
- Karla Beatriz Tafur Bances
- Karla Zepeda
- Kary Kelly
- Kate Harden
- Kate Jaegle
- Kate Zenlea
- Katherine Smith
- Katherine Stapleton
- Kathleen Linder
- Kathleen M. Mullane
- Kathleen M. Neuzil
- Kathleen Menasche
- Kathleen S. Jones
- Kathryn E. Stephenson
- Kawsar R. Talaat
- Keith R. Jerome
- Keith W. Vrbicky
- Kelly Kush
- Kelly McQuarrie
- Ken Ho
- Kendra Enright
- Kendra Lisec
- Kenneth Finkelstein
- Kenneth H. Mayer
- Kenneth Steil
- Kevin D. Cannon
- Kevin Parks
- Kevin Zhang
- Kia Lee
- Kia Lee
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- Kimberly Mueller
- Kimberly Nieves
- Kimberly Nofz
- Kimberly Snell
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- Kristen Kiersey
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- Kristin Marks
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- Laura Kogelman
- Laura Pearlman
- Laura Pearlman
- Laura Porterfield
- Laura Ruy Sanchez Guerrero
- Laura Stulken
- Lauren Clement
- Lauren Newhouse
- Laurence Chu
- Laurie J. Han-Conrad
- Lawrence Corey
- Lawrence J. Purpura
- Lazaro Gonzalez
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- Lee Tomatsu
- Leena Paul
- Leila Hojat
- Leland N. Allen III
- Lena R. Freese
- Leonard Singer
- Les B. Forgosh
- Lesley Browder
- Leslie A. Edwards
- Leslie Iverson
- Lilly Immergluck
- Lily Aleman
- Lina M. Forero
- Linda M. Schipani
- Linda Murray
- Linda R. Belhorn
- Lindsey R. Baden
- Lisa A. Jackson
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- Lisa Cohen
- Lisa Holloway
- Lisa J. Sanders
- Lisa Johnson
- Lisa M. Dunkle
- Lisa S. Usdan
- Lisa Stangl
- Lisa Stevens Rameaka
- Logan Ledbetter
- Lois Katz
- Lora J. McGill
- Lori Nesbitt
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- Luis H. González
- Luis I. De La Cruz
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- Luz Zapata
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- Lynne A. Haughey
- M. Juliana McElrath
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- Maggie Lewis
- Mai Pham
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- Marcus J. Zervos
- Marcy Kulic
- Margaret Cheng
- Margaret E. McCort
- Margaret Kautz
- Margaret Powers-Fletcher
- Margaret Rhee
- Margaret Wells
- Marguerite Neill
- Maria G. Becerra
- Maria Hernandez Moran
- Maria I. Bermudez
- Maria Johnson
- Maria L. Alcaide
- Maria M. Regalado
- Maria Mileno
- Marian E. Shaw
- Marianela Carvajal
- Maricruz E. Ortegón
- Marina Lee
- Mario Castro
- Mark A. Turner
- Mark E. Kutner
- Mark Eickhoff
- Mark Hutchens
- Mark Leibowitz
- Mark Lerman
- Mark M. McKenzie
- Mark S. Adams
- Marshall A. Cross
- Marshall Nash
- Martha Carmen Medina
- Martha Cecilia Gómora Madrid
- Martha Nason
- Martha Sanchez
- Martín Bäcker
- Marvin Castellon
- Mary A. Marovich
- Mary Beth Manning
- Mary C. Walsh
- Mary Easley
- Mary Hussain
- Mary Smith
- Mary Vogler
- Maryam Jahromi
- Maryrose Laguio-Vila
- Marysol Villegas
- María E. Santolaya
- María I. Rivera
- María José Reyes Fentanes
- Masaru Oshita
- Mashrur Islam Majumder
- Matthew B. Laurens
- Matthew D. Sims
- Matthew G. Davis
- Matthew Hepburn
- Matthew Hong
- Matthew Hong
- Matthew Miles
- Matthew W. Doust
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- Michael Cancilla
- Michael Cancilla
- Michael Chung
- Michael Delgado
- Michael Desjardins
- Michael E. Dever
- Michael Fay
- Michael J. Cotugno
- Michael J. Koren
- Michael J. McCartney
- Michael J. Smith
- Michael Jacobs
- Michael L. Levin
- Michael Lewis
- Michael P. Dube
- Michael R. Adams
- Michael Sciaudone
- Michael Waters
- Michele Baka
- Michele D. Reynolds
- Michele P. Andrasik
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- Michelle DallaPiazza
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- Michelle Haynes
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- Michelle Saemann
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- Mohammed Antwi
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- Nga Le
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- Oyebisi Olanrewaju
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- Paola Lichtenberger
- Parke Hedges
- Parul Desai
- Patricia L. Winokur
- Patrick A. Oliver
- Patrick Flume
- Patrick Newingham
- Patty Howenstine
- Patty Price-Abbott
- Patty Reed
- Paul A. Goepfert
- Paul Bondy
- Paul Coplan
- Paul Cramer
- Paul E. Wylie
- Paul G. Matherne
- Paul H. Wakefield
- Paul J. Nugent
- Paul Kilgore
- Paul Nee
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- Paul S. Bradley
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- Peter Ronco
- Philip Ponce
- Phillip Claybrook
- Phillip Levy
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- Purvi Parikh
- R. Michelle Chouteau
- R. Scott McClelland
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- Thomas Weiss
- Tiffany Esinhart
- Tiffany Nemecek
- Tiffany Schwasinger-Schmidt
- Tilly Varughese
- Timothy J. Hatlen
- Timothy P. Vachris
- Timothy Shope
- Timothy W. Schacker
- Timothy Wilkin
- Tina Tong
- Tina Wang
- Toby Briskin
- Todd Simmons
- Tom Fiel
- Toni Robinson
- Toni White
- Tracy Okonya
- Tracy R. Klein
- Trina L. Reynolds
- Troy Holdeman
- Tyler D. Bold
- Uriel R. Felsen
- Valentine M. Ebuh
- Valeria D. Cantos
- Valerie K. Arnold
- Vanessa Abad
- Vanessa Raabe
- Veronica G. Fragoso
- Veronica Garcia-Fragoso
- Veronica Procasky
- Veronica Viar
- Vicki E. Miller
- Vickie Leathers
- Victoria Andriulis
- Victoria Engler
- Victoria Mosteller
- Victoria R. Anderson
- Vida Veronica Ruiz Herrera
- Vincent Huynh
- Vincent Mirkil
- Vivek Rajasekhar
- Viviana Gonzalez
- Vladimir Berthaud
- Walter Patton
- Wanda Ramon
- Waseem Chughtai
- Wayne L. Harper
- Wayne Woo
- Wendell Lewis
- Wendell Lewis III
- Wendy A. Keitel
- Wesley Campbell
- Wesley Van Ever
- Westly Keating
- Whitney West
- Will Hernandez
- William B. Davis
- William B. Smith
- William H. Jones
- William Jennings
- William Kirby
- William P. Silver
- William R. Hartman
- William S. Davis Jr.
- William Schnitz
- William Seger
- Winniberg Stephany Alvarez León
- Winston Cavert
- Xiaomi Tong
- Yaa D. Oppong
- Yi H. Wu
- Ying Huang
- Yogesh K. Paliwal
- Youyi Fong
- Yunda Huang
- Yunda Huang
- Yvonne Davis
- Zachary Bittner
- Zainab Rizvi
- Zindy Yazmín Zárate Hinojosa
- Zudi-Mwak Takizala
- Publication venue
- Elsevier
- Publication date
- 01/10/2023
- Field of study
Summary: Background: While vaccines have established utility against COVID-19, phase 3 efficacy studies have generally not comprehensively evaluated protection provided by previous infection or hybrid immunity (previous infection plus vaccination). Individual patient data from US government-supported harmonized vaccine trials provide an unprecedented sample population to address this issue. We characterized the protective efficacy of previous SARS-CoV-2 infection and hybrid immunity against COVID-19 early in the pandemic over three-to six-month follow-up and compared with vaccine-associated protection. Methods: In this post-hoc cross-protocol analysis of the Moderna, AstraZeneca, Janssen, and Novavax COVID-19 vaccine clinical trials, we allocated participants into four groups based on previous-infection status at enrolment and treatment: no previous infection/placebo; previous infection/placebo; no previous infection/vaccine; and previous infection/vaccine. The main outcome was RT-PCR-confirmed COVID-19 >7–15 days (per original protocols) after final study injection. We calculated crude and adjusted efficacy measures. Findings: Previous infection/placebo participants had a 92% decreased risk of future COVID-19 compared to no previous infection/placebo participants (overall hazard ratio [HR] ratio: 0.08; 95% CI: 0.05–0.13). Among single-dose Janssen participants, hybrid immunity conferred greater protection than vaccine alone (HR: 0.03; 95% CI: 0.01–0.10). Too few infections were observed to draw statistical inferences comparing hybrid immunity to vaccine alone for other trials. Vaccination, previous infection, and hybrid immunity all provided near-complete protection against severe disease. Interpretation: Previous infection, any hybrid immunity, and two-dose vaccination all provided substantial protection against symptomatic and severe COVID-19 through the early Delta period. Thus, as a surrogate for natural infection, vaccination remains the safest approach to protection. Funding: National Institutes of Health
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Risk of COVID-19 after natural infection or vaccinationResearch in context
- Author
- Abad Vanessa
- Abate Getahun
- Abbas Anum
- Ackerman Jamie
- Ackerman Ronald
- Ackermann Jeremy
- Adams Atoya
- Adams Mark S.
- Adams Michael R.
- Adelglass Jeffrey
- Afework Sarah
- Ahmad Nina
- Akamine Christine
- Ake Julie A.
- Al-Ibrahim Mohamed S.
- Albert Gary
- Alcaide Maria L.
- Alderson Nathan
- Aleman Lily
- Alemán José O.
- Allaw Mohammed
- Alva E. Javier Pretell
- Alvarado Hilario
- Amador Carmen
- Andersen James
- Anderson Corey G.
- Anderson Evan J.
- Anderson Victoria R.
- Andes David R.
- Andrasik Michele P.
- Andree Stephanie
- Andrews Jeb
- Andriesen Jessica G.
- Andriulis Victoria
- Ansel Jessica L.
- Anthony Codi M.
- Antwi Mohammed
- Arduino Roberto C.
- Aristy Florida
- Arnold Valerie K.
- Arrazcaeta Alicia
- Atmar Robert L.
- Avworo Ayoade
- Bacher Christina
- Baden Lindsey R.
- Badillo Diana
- Bainbridge Emma
- Baka Michele
- Baker Sherrie
- Balani Bindu
- Ball Brandy
- Bances Karla Beatriz Tafur
- Baron Mira
- Barranco-Santana Elizabeth
- Bartilucci Darlene
- Bashour Jennifer
- Batteiger Teresa A.
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- Shairi Samira
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- Shannon Amie
- Shapiro Adrienne E.
- Sharp Stephan C.
- Shaw Marian E.
- Shelly Rozeli
- Shelton Sandra
- Sherman Amy
- Sheth Neil P.
- Shinn Steven
- Shlotzhauer Tammi L.
- Shope Timothy
- Shopsin Bo
- Shoptaw Steven
- Siddiqui Farhan
- Siegel Marc
- Sierra Dianca
- Silver William P.
- Simmons Todd
- Simon Gary
- Sims Matthew D.
- Singer Leonard
- Singletary Justin
- Skipper Stephanie
- Slechta Stacy
- Sligh Teresa S.
- Smith Candace
- Smith Derek M.
- Smith Katherine
- Smith Mary
- Smith Michael J.
- Smith William B.
- Snell Kimberly
- Sobhanie M. Mahdee
- Sobieszczyk Magdalena E.
- Sogbetun Obiageli
- Solis Joel
- Sonnier Cora
- Sopher Carrie
- Sovic Brit
- Spector Stephen A.
- Sperber Steven
- Staben Jonathan
- Stahl Jessica
- Stanford Amber
- Stangl Lisa
- Stanton Ariana C.
- Stapleton Jack
- Stapleton Katherine
- Starlin Richard
- Starr Amy
- Starr Ryan P.
- Steil Kenneth
- Stephenson Carolene
- Stephenson Kathryn E.
- Sterling Stephanie
- Stewart Brittany
- Striker Robert
- Strout Cynthia Becher
- Struyf Frank
- Studdard Suzanna
- Stulken Laura
- Stull Mildred
- Sturgeon Rodney E.
- Suen May-Yin
- Sugimoto Danny
- Suyehira Janice
- Swaminathan Shobha
- Swan Suzanne
- Swann Edith
- Swanson Austin
- Sweet Christy
- Swieboda Elisa
- Syndergaard Scott N.
- Takizala Zudi-Mwak
- Takuva Simbarashe G.
- Talaat Kawsar R.
- Tan Chen S.
- Tapia Milagritos
- Tarakjian Denis
- Tashima Karen
- Tatelbaum David
- Taylor Barbara S.
- Taylor Brandie
- Tedder-Edwards Sharita
- Teherani Meghan
- Theodore Deborah A.
- Thessing Jeffrey
- Thomas Meagan
- Thomas-Seaton LaTeshia
- Thompson Amy
- Thompson Karl M.
- Thompson-Seim Teri
- Thomsen Isaac
- Tieu Hong V.
- Toma Ramy J.
- Tomaszewski Christian
- Tomatsu Lee
- Tomlinson Ryan
- Tong Tina
- Tong Xiaomi
- Torres Juan P.
- Torres Julian A.
- Tovar Dalia
- Tran Carolyn
- Treanor John J.
- Tukuru Sade
- Turley Christine B.
- Turner Mark A.
- Tyson Stefanie
- Ulrich Robert J.
- Usdan Lisa S.
- Utz Gregory C.
- Vachris Timothy P.
- Valenti Bruno
- Valika Insiya
- Van Der Leden Mimi
- Van Dromme Ilse
- Van Ever Wesley
- Van Roey Griet
- Varughese Tilly
- Vega Jocelyn Zuleica Olmos
- Vega Norma
- Vegas Diana
- Vertucci Michele
- Viar Veronica
- Viens Nicholas A.
- Villegas Marysol
- Vingerhoets Johan
- Vogler Mary
- Vowell Mandy
- Vrbicky Keith W.
- Wahlin Tami
- Wakefield Paul H.
- Wald Anna
- Walker James
- Walker Shannon
- Walsh Edward E.
- Walsh Mary C.
- Walsh Stephen R.
- Walsh Stephen R.
- Walter Emmanuel B.
- Walters Ayanna
- Wang Tina
- Warden Ashley
- Waters Michael
- Watkins Breanz
- Webb Angella
- Webster Hala
- Weidler Jessica L.
- Weiss Thomas
- Wells Margaret
- Wendell Lewis III
- Wendrow Andrea
- Werne Melody
- West Whitney
- Whatley Jordan L.
- Whitaker Jennifer A.
- White Jewel J.
- White Julie
- White Toni
- Wijewardane Priyantha N.
- Wilkin Timothy
- Wilkinson Bethanie
- William S. Davis Jr
- Williams Barton G.
- Williams Hayes
- Williams Samantha
- Wilson Christine
- Wilson Clint
- Wilson Greg
- Wilson Natasha
- Winbigler Jennifer
- Winkle Peter J.
- Winokur Patricia L.
- Witbeck John
- Wohl David
- Woo Wayne
- Woodside Leana
- Wortman Glenn
- Wu Yi H.
- Wylie Paul E.
- Yang Fan
- Yang Kinara S.
- Yoon Anelgine C.
- York Jill
- Young Cheryl
- Yu Chenchen
- Yusin Joseph
- Zapata Luz
- Zash Rebecca
- Zegarra Eneyda Giuvanela Llerena
- Zemanek Arthur L.
- Zenlea Kate
- Zepeda Karla
- Zervos Marcus J.
- Zhai Nan
- Zhang Kevin
- Zhou James
- Zimmer Andrea
- Zingman Barry S.
- Zorrilla Carmen D.
- Áñez Germán
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/10/2023
- Field of study
Background: While vaccines have established utility against COVID-19, phase 3 efficacy studies have generally not comprehensively evaluated protection provided by previous infection or hybrid immunity (previous infection plus vaccination). Individual patient data from US government-supported harmonized vaccine trials provide an unprecedented sample population to address this issue. We characterized the protective efficacy of previous SARS-CoV-2 infection and hybrid immunity against COVID-19 early in the pandemic over three-to six-month follow-up and compared with vaccine-associated protection. Methods: In this post-hoc cross-protocol analysis of the Moderna, AstraZeneca, Janssen, and Novavax COVID-19 vaccine clinical trials, we allocated participants into four groups based on previous-infection status at enrolment and treatment: no previous infection/placebo; previous infection/placebo; no previous infection/vaccine; and previous infection/vaccine. The main outcome was RT-PCR-confirmed COVID-19 >7–15 days (per original protocols) after final study injection. We calculated crude and adjusted efficacy measures. Findings: Previous infection/placebo participants had a 92% decreased risk of future COVID-19 compared to no previous infection/placebo participants (overall hazard ratio [HR] ratio: 0.08; 95% CI: 0.05–0.13). Among single-dose Janssen participants, hybrid immunity conferred greater protection than vaccine alone (HR: 0.03; 95% CI: 0.01–0.10). Too few infections were observed to draw statistical inferences comparing hybrid immunity to vaccine alone for other trials. Vaccination, previous infection, and hybrid immunity all provided near-complete protection against severe disease. Interpretation: Previous infection, any hybrid immunity, and two-dose vaccination all provided substantial protection against symptomatic and severe COVID-19 through the early Delta period. Thus, as a surrogate for natural infection, vaccination remains the safest approach to protection. Funding: National Institutes of Health
Long-term neurological symptoms after acute COVID-19 illness requiring hospitalization in adult patients: insights from the ISARIC-COVID-19 follow-up study
- Author
- Ada Ebo
- Adam Ali
- Adrian Streinu-Cercel
- Adrien Auvet
- Adrien Lemaignen
- Agnès Meybeck
- Agnès Sommet
- Aidan Burrell
- Alamin Mustafa
- Albert Sotto
- Aldric Manuel
- Alexa Debard
- Alexander J Mentzer
- Alexandra Bedossa
- Alexandre Ducancelle
- Alexandre Gaymard
- Alexandre Hoctin
- Ali Hachemi
- Aline-Marie Florence
- Alison M Meynert
- Alistair D Nichol
- Aliya Mohammed Alameen
- Alpha Diallo
- Alphonsine Diouf
- Amal Abrous
- Amanda Rojek
- Amandine Gagneux-Brunon
- Amiel A Dror
- Ana da SilvaFilipe
- Anatoliy Gavrylov
- Anca Streinu-Cercel
- Anders Tveita
- Andrea Angheben
- Andrea Cortegiani
- Andrea Rossanese
- Andreas Lind
- Andrew Dagens
- André Cabie
- Andy Law
- Anissa Chair
- Ankana Satya
- Anna Beltrame
- Anne Conrad
- Anne Guillaumot
- Anne Margarita Dyrhol-Riise
- Anne-Hélène Boivin
- Anne-Sophie Boureau
- Anne-Sophie Resseguier
- Annemarie B Docherty
- Anthony Lemeur
- Anthony Nghi
- Antoine Cheret
- Antoine Khalil
- Antoine Kimmoun
- Antoine Merckx
- Antonia Ho
- Antonia Ricchiuto
- Antonio Lalueza
- Ariel Bolanga
- Arnaud Scherpereel
- Arne Søraas
- Arsène Kpangon
- Aurore Bousquet
- Aurélie Papadopoulos
- Aurélie Veislinger
- Aurélie Wiedemann
- Axelle Braconnier
- Barbara Wanjiru Citarella
- Bato Hammarström
- Battaglini Denise
- Beatrice Alex
- Benjamin Bach
- Benjamin Lefèvre
- Benjamine Sarton
- Benoit Visseaux
- Benoît Roze
- Benoît Thill
- Berline Fotso
- Bernard Cholley
- Bertrand Dussol
- Birgitte Stiksrud
- Blandine Rammaert
- Bouchra Loufti
- Brigitte Elharrar
- Bruno Levy
- Bruno Lina
- Bruno Pastene
- Bénédicte Lefebvre
- Cameron J Fairfield
- Camile Bouisse
- Camille Couffignal
- Cammandji Damien
- Carine Roy
- Caroline Mudara
- Carrol Gamble
- Catherine A Shaw
- Catherine Chakveatze
- Catherine Chirouze
- Cecile Azoulay
- Cedric Djadda
- Charlene Da Silveira
- Charline Vauchy
- Charlotte Charpentier
- Charlotte Summers
- Chiara Piubelli
- Cho Sung-Min
- Christelle Delmas
- Christelle Paul
- Christelle Tual
- Christian Rabaud
- Christiana Kartsonaki
- Christl A Donnelly
- Christophe Fraser
- Christophe Rapp
- Christopher A Green
- Claire Andrejak
- Claire Levy-Marchal
- Clare Jackson
- Clark D Russell
- Claudine Badr
- Clotilde Allavena
- Clément Bihan
- Colin McArthur
- Coralie Tardivon
- Cristina De Rose
- Cyril Bris
- Cyril Cadoz
- Cécile Goujard
- Cécile Mear-Passard
- Cécile Tromeur
- Cécile Yelnik
- Cédric Joseph
- Cédric Laouénan
- Céline Dorival
- Céline Ficko
- Céline Michelanglei
- Damien Bouhour
- Daniel Glikman
- Daniel Perez
- Danielle Jaafar
- Danilo Buonsenso
- Dario Sinatti
- David L Robertson
- David Stuart
- David Zucma
- Debby Bogaert
- Deepjyoti Kalita
- Delphine Bachelet
- Delphine Bergeaud
- Delphine Lariviere
- Denis Garot
- Denis Malvy
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Denise Battaglini
- Diana Hernandez
- Diane Descamps
- Diane Ponscarme
- Didier Laureillard
- Dominique Deplanque
- Dominique Luton
- Donald Buri
- Drashti Patel
- Duc Nguyen
- Eder Caceres
- Edouard Soum
- Eglantine Ferrand Devouge
- Egle Saviciute
- Elisa Demonchy
- Elisabeth Botelho-Nevers
- Elisabetta Spinuzza
- Elise Artaud-Macari
- Elodie Curlier
- Elsa Nyamankolly
- Else Quist-Paulsen
- Emma C Thomson
- Emmanuelle Denis
- Emmanuelle Mercier
- Eric Delaveuve
- Eric D’Ortenzio
- Eric Oziol
- Eric Senneville
- Erwan Fourn
- Erwan L’Her
- Esteban Garcia-Gallo
- Etienne De Montmollin
- Eva Geraud
- Eve Defous
- Ewen M Harrison
- Eyrun Floerecke Kjetland Kjetland
- Eyvind W Axelsen
- Fabrice Laine
- Fanny Vuotto
- Fara Diop
- Fernanda Dias Da Silva
- Fiona Griffiths
- Firouzé Bani-Sadr
- Florence Jego
- Florent Peelman
- Florentia Kaguelidou
- Fouda Atangana
- France Mentré
- François Angoulvant
- François Dubos
- François Goehringer
- François Téoulé
- François-Xavier Catherine
- François-Xavier Ferrand
- François-Xavier Lescure
- Fredrik Müller
- Félix Djossou
- Gabriel Macheda
- Gail Carson
- Galyna Kutsyna
- Gary Leeming
- Gayatri Vishwanathan
- Geoffrey Liegeon
- Georges Falher
- Georgios Pollakis
- Gervais Eneli
- Gilles Peytavin
- Girish Sindhwani
- Giulia Bertoli
- Grace Assi
- Graham S Cooke
- Grégory Corvaisier
- Guillame Louis
- Guillaume Lingas
- Guillaume Martin-Blondel
- Guillermo Giordano
- Guylaine Castor-Alexandre
- Gwenaël Moal
- Gwenhaël Colin
- Haider Hirkani
- Hayley Hardwick
- Hervé Nagard
- Hiba Zayyad &
- Hikombo Hitoto
- Hodane Yonis
- Hugo Mouquet
- Hugues Aumaitre
- Hugues Cordel
- Husna Begum
- Hélène Esperou
- Hélène Salvator
- Ikram Houas
- Ilka Engelmann
- Ingrid G Bustos
- Isabela Bolaños
- Isabelle Delacroix
- Isabelle Enderle
- Isabelle Fabre
- Isabelle Gorenne
- Isabelle Hoffmann
- Isabelle Michelet
- ISARIC Clinical Characterization Group Laurent Abel
- Jade Ghosn
- Jaime Cruz Rojo
- Jake Dunning
- James Lee
- James Scott-Brown
- Janet Harrison
- Janet T Scott
- Jean Baptiste Assie
- Jean-Benoît Arlet
- Jean-Charles Gagnard
- Jean-Daniel Lelievre
- Jean-François Payen
- Jean-François Timsit
- Jean-Luc Diehl
- Jean-Marc Chapplain
- Jean-Marie Turmel
- Jean-Sébastien Hulot
- Jeanne Sibiude
- Jeanne Truong
- Jennifer Lee
- Jia Wei
- Jimmy Mullaert
- Jo Dalton
- Joaquín Baruch
- Johann Auchabie
- John Arne Dahl
- John Kenneth Baillie
- John Marshall
- Jose Andres Calvache
- José Luis Bernal Sobrino
- Juan Luis Cruz Bermúdez
- Jules Bauer
- Julie Chas
- Julie Mankikian
- Julien Jabot
- Julien Moyet
- Julien Poissy
- Justine Pages
- Jérémie Guedj
- Jérémie Pasquier
- Jérôme Dimet
- Kalynn Kennon
- Kamal Abu Jabal
- Karen Delavigne
- Karine Bezulier
- Karine Faure
- Karine Risso
- Kazali Enagnon Alidjnou
- Kenneth A McLean
- Krish Kherajani
- Krishna Bhavsar
- Kristian Tonby
- Kyle Gomez
- Kévin Alexandre
- Kévin Bouiller
- Kévin Didier
- Laetitia Bodenes
- Lance C. W. Turtle
- Lars Heggelund
- Laura Marsh
- Laura Merson
- Laure Goubert
- Lauren Eloundou
- Laurence Bouillet
- Laurence Maulin
- Laurent Bitker
- Laurent Guilleminault
- Laurent Lefebvre
- Laurent Mandelbrot
- Laurent Plantier
- Laurent Richier
- Laurène Azemar
- Leonard Numfor
- Liem Luong
- Lila Bouadma
- Linda Gail Skeie
- Linn Margrete Eggesbø
- Lionel Piroth
- Liv Hesstvedt
- Louis Gerbaud Morlaes
- Louise Sigfrid
- Lucia Moro
- Lucie Fevre
- Lucille Blumberg
- Lysa Tagherset
- Léo Chenard
- Mahdad Noursadeghi
- Mahendra Singh
- Maire-Laure Casanova
- Malcolm G Semple
- Manuel Etienne
- Manuel Rosa-Calatrava
- Manuella Ademnou
- Marc Fabre
- Marc Lambert
- Marc Leone
- Margaux Isnard
- Maria Zambon
- Mariachiara Ippolito
- Marie Bartoli
- Marie Connor
- Marie Gominet
- Marie Lachatre
- Marie Lacoste
- Marie Lagrange
- Marie Langelot-Richard
- Marie Rafiq
- Marie-Capucine Tellier
- Marie-Charlotte Chopin
- Marie-Christine Carret
- Marie-Pierre Debray
- Marielle Boyer-Besseyre
- Marielle Buisson
- Marina Esposito-Farese
- Marine Beluze
- Marine Livrozet
- Marion Maréchal
- Marion Schneider
- Marion Zabbe
- Mark G Pritchard
- Marlène Murris
- Marta Alessi
- Martin Guego
- Martin Martinot
- Martine Remy
- Massimo Palmarini
- Mathew Thorpe
- Mathieu Blot
- Mathieu Lesouhaitier
- Mathieu Mattei
- Mathilde Desvallées
- Matthew Hall
- Matthieu Revest
- Maude Bouscambert
- Maxime Hentzien
- Mayka Mergeay-Fabre
- Maïder Pagadoy
- Meera Chand
- Mehdi Mezidi
- Mercé Jourdain
- Merete Ellingjord-Dale
- Merson Laura
- Michael Edelstein
- Michelle Girvan
- Miles Lunn
- Minerva Cervantes-Gonzalez
- Minh Le
- Mirjam Evers
- Mohammed ElSanharawi
- Moise Massoma
- Moïse Machado
- Murray Dryden
- Murray Wham
- Mylène Maillet
- Mélanie Roriz
- Nadhem Lafhej
- Nadia Ouamara
- Nadia Saidani
- Nadir Hadri
- Nadège Neant
- Nastia Medombou
- Natalie Wright
- Nathalie Allou
- Nathalie DeCastro
- Nathalie Dournon
- Nathalie Pansu
- Nathan Peiffer-Smadja
- Nerissa Niba
- Nicholas Sedillot
- Nicolas Benech
- Nicolas Carlier
- Nicolas Ferriere
- Nicolas Terzi
- Noelia García Barrio
- Noémie Mercier
- Noémie Tissot
- Noémie Vanel
- Oana Săndulescu
- Odile Launay
- Oksana Kruglova
- Olga Martynenko
- Olivier Bouchaud
- Olivier Epaulard
- Olivier Lairez
- Olivier Lesens
- Olivier Picone
- Olivier Robineau
- Olivier Sanchez
- Olivier Terrier
- Ouifiya Kafif
- Palmer Masumbe
- Paola Rodari
- Pascal Granier
- Pasquale Anania
- Patrick Imbert
- Patrick Rispal
- Patrick Rossignol
- Paul Dunand
- Paul Henri Wicky
- Paul Klenerman
- Paul Loubet
- Paul Otiku
- Pauline Caraux-Paz
- Peter Horby
- Peter Openshaw
- Philippine Eloy
- Piero L Olliaro
- Piero Valentini
- Pierre Delobel
- Pierre Ondobo
- Pierre Tattevin
- Pierre-Adrien Bolze
- Pierre-François Sandrine
- Pierre-Marie Roger
- Premraj Lavienraj
- Pulak Kedia
- Quentin Hingrat
- Quentin Lepiller
- Rachael Parke
- Rachel Essaka
- Rachida Ouissa
- Rafael Mahieu
- Raphaël Borie
- Raphaël Favory
- Rebecca Hamidfar
- Renaud Tamisier
- Richa Su
- Riinu Pius
- Roar Bævre-Jensen
- Robba Chiara
- Robert A Fowler
- Roberta Meta
- Rohan Shetty
- Romain Basmaci
- Romain Decours
- Romain Guery
- Ross Hendry
- Rostane Gaci
- Roxane Courtois
- Rupert Higgins
- Ryadh Pokeerbux
- Ryan S Thwaites
- Saad Nseir
- Sabelline Bouchez
- Sabina Kali
- Sadie Kelly
- Sakshi Lath
- Salma Jaafoura
- Samira Laribi
- Samreen Ijaz
- Samuel Markowicz
- Sandra Bichoka
- Sandrine Couffin-Cadiergues
- Sara Clohisey
- Sarah E McDonald
- Sarah Moore
- Sarah Redl
- Sarah Stabler
- Sarah Tubiana
- Saye Khoo
- Segolène Greffe
- Seán Keating
- Shiranee Sriskandan
- Shona C Moore
- Simon Bessis
- Simon-Djamel Thiberville
- Soizic Mestre
- Sonja Hjellegjerde Brunvoll
- Sophie Halpin
- Sophie Letrou
- Sophie Mahy
- Srinivas Murthy
- Stanislas Rebaudet
- Stephanie Kouba
- Stephanie Roberts
- Stephen R Knight
- Steve Webb
- Stéphane Jaureguiberry
- Stéphane Lasry
- Stéphanie Cousse
- Stéphanie Fry
- Sue Smith
- Susanne Dudman
- Sybille Bevilcaqua
- Sylvain Diamantis
- Sylvie Behilill
- Sylvie Kwedi
- Sylvie LeGac
- Sylvie Lion-Daolio
- Sylvie Van Der Werf
- Synne Jenum
- Sébastien Preau
- Sérgio Gaião
- Séverine Ansart
- Thibault Chiarabini
- Thierry Carmoi
- Thierry Mazzoni
- Thomas Drake
- Thomas Flament
- Thomas Guimard
- Thomas Maitre
- Thomas Perpoint
- Thomson David
- Thushan de Silva
- Tiffany Trouillon
- Timothy M Uyeki
- Tiphaine Goulenok
- Tom Fletcher
- Tom Solomon
- Tristan Gigante
- Trude Steinsvik
- Vadim Tieroshyn
- Valentine Campana
- Valérie Gaborieau
- Valérie Garrait
- Valérie Gissot
- Vanessa Sancho-Shimizu
- Vanina Meysonnier
- Vegard Skogen
- Ventzislava Petrov-Sanchez
- Victoria Manda
- Victoria Shaw
- Vincent Dinot
- Vincent Dubee
- Vincent Enouf
- Vincent Langlois
- Vincent Moing
- Vincent Peigne
- Vincent Pestre
- Vincent Thibault
- Véronique Lemee
- Waasila Jassat
- Walter Picard
- Wanjiru Citarella Barbara
- Wendy S Barclay
- White Nicole M
- William A Paxton
- William Finlayson
- William Greenhalf
- Wilna Oosthuyzen
- Xavier Duval
- Yanay Gorelik
- Yash Doshi
- Yazdan Yazdanpanah
- Yoan Lavie-Badie
- Yock Ping Chow
- Younes Ait Tamlihat
- Younes Kerroumi
- Yves Levy
- Zeno Bisoffi
- Publication venue
- Publication date
- 06/12/2023
- Field of study
in this study we aimed to characterize the type and prevalence of neurological symptoms related to neurological long-COVID-19 from a large international multicenter cohort of adults after discharge from hospital for acute COVID-19
Paediatric COVID-19 mortality: a database analysis of the impact of health resource disparity
- Author
- Aasiyah Rashan
- Abid Khatak
- Abigail Beane
- Adrian Streinu-Cercel
- Adrien Auvet
- Adrien Lemaignen
- Adrienne Chan
- Agnes Meybeck
- Agnes Sommet
- Agnieszka Oldakowska
- Agostinho Monteiro
- Ahmad Afiq Ramli
- Ahmad Kashfi Rahman
- Ahmed Farooq
- Aidan Burrell
- Albert Groenendijk
- Albert Sotto
- Albertus Beishuizen
- Aldric Manuel
- Alexa Debard
- Alexander Daniel Cornet
- Alexander J Mentzer
- Alexandra Bedossa
- Alexandra Coelho
- Alexandre Ducancelle
- Alexandre Gaymard
- Alexandre Hoctin
- Ali Hachemi
- Alif Adlan Thabit
- Alison M. Meynert
- Alistair Nichol
- Alpha Diallo
- Alphonsine Diouf
- AM Udara Attanyake
- Amanda Corley
- Amanda Rojek
- Amandine Gagneux-Brunon
- Amina Meziane
- Amirul Asyraf
- Amna Faheem
- Amélie Valran
- Ana Freitas Ribeiro
- Ana L Rios
- Ana Martins
- Ana Silva Filipe
- Anant Kataria
- Anca Streinu-Cercel
- Andrea Angheben
- Andrea Rossanese
- Andrew Dagens
- Andrew Udy
- Andrey Svistunov
- André Cabié
- André Dias
- Andy Law
- Anika Atique
- Anilawati Mat Jelani
- Anissa Chair
- Anja Grosse Lordemann
- Anjellica Chen
- Anna Beltrame
- Anne Conrad
- Anne Guillaumot
- Anne McCarthy
- Anne-Hélène Boivin
- Anne-Marie Guerguerian
- Anne-Sophie Boureau
- Anne-Sophie Resseguier
- Annelies Verbon
- Annemarie B. Docherty
- Annmarie O'Callaghan
- Ansley Hamer
- Anthony L. Loschner
- Anthony Lemeur
- Anthony Nghi
- Antoine Cheret
- Antoine Khalil
- Antoine Kimmoun
- Antoine Merckx
- Antonia Ho
- Antonio Lalueza
- António Mesquita
- Arabella Fahy
- Ardiyan Apriyana
- Arfan Ikram
- Aria Kekalih
- Arianne Joy Corpuz
- Arjen M Dondorp
- Arnaud Scherpereel
- Arsene Kpangon
- Ary Serpa Neto
- Asgar Rishu
- Ashraf Sheharyar
- Asma Moin
- Astarini Hidayah
- Attaur Rehman
- Audrey Barrelet
- Aurore Bousquet
- Aurélie Papadopoulos
- Aurélie Veislinger
- Aurélie Wiedemann
- Axelle Braconnier
- Azlan Mat Soom
- B. P Edouard Soum
- Barbara Wanjiru Citarella
- Basri Mat Nor
- Beatrice Alex
- Benedict Sim Heng
- Benjamin Bach
- Benjamin Lefèvre
- Benjamine Sarton
- Benoit Thill
- Benoit Visseaux
- Benoît Roze
- Bernard Cholley
- Bernardo Ferreira
- Bertrand Dussol
- Bharath Kumar Vijayaraghavan
- Bianca Boxma
- Biing Horng Lee
- Blandine Rammaert
- Bouchra Loufti
- Brenda Reeve
- Brigitte Elharrar
- Bronner P Gonçalves
- Bronner P. Gonçalves
- Bruno Levy
- Bruno Lina
- Bruno Pastene
- Bénédicte Lefebvre
- Bénédicte Rossignol
- Calum Semple
- Calvin Wong
- Cameron J. Fairfield
- Camile Bouisse
- Camille Couffignal
- Carine Roy
- Carlo Giaquinto
- Carlos Alexandre Brito
- Carlos Lumbreras Bermejo
- Carlos Pimentel
- Carola Pierobon
- Carolien van Netten
- Caroline Martins Rego
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- Michele Petrovic
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- Pauline Caraux-Paz
- Pavan Kumar Vecham
- Pedro Faria
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- Peter Horby
- Peter Kiiza
- Peter Openshaw
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- Petr Glybochko
- PG Ishara Udayanga
- Philippe Jouvet
- Philippine Eloy
- Phoebe Ampaw
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- Piero L. Olliaro
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- Pierre-François Sandrine
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- Prasan Kumar Panda
- Pratap Karpayah
- Quentin Le Hingrat
- Quentin Lepiller
- Quratul Ain Khan
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- Rachida Ouissa
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- Rafael Mahieu
- Raphael Favory
- Raphaël Borie
- Raquel Pinto
- Rashan Haniffa
- Rasidah Bt Senian
- Raul Neto
- Rebecca Hamidfar
- Renata Barbalho
- Richard S. Tedder
- Riinu Pius
- Rima Song
- Rita Alves
- Rob Klont
- Robert A Fowler
- Robert A. Fowler
- Roberta Cavalin
- Robin Kobbe
- Rodrigo Díaz
- Romain Basmaci
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- Romans Matulevics
- Ross Hendry
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- Roxane Courtois
- Rozanah Abd Rahman
- Rui Caetano Garcês
- Rui Pereira
- Rupert Higgins
- Ruth Lyons
- Ryadh Pokeerbux
- Ryan Khoo
- Ryan S Thwaites
- Saad Nseir
- Sabelline Bouchez
- Sabina Kali
- Sabina Mason
- Sabine Cornelis
- Sabine Croonen
- Sadie Kelly
- Saef Umar Barnett
- Saijad Orakzai
- Sally Shrapnel
- Salma Jaafoura
- Samantha Lissauer
- Samira Laribi
- Samreen Ijaz
- Samuel Hinton
- Samuel Markowicz
- Sandrine Couffin-Cadiergues
- Sanka Sri Darshana
- Sanne Wesselius
- Santi Dewayanti
- Saptadi Yuliarto
- Sara Clohisey
- Sara Machado
- Sarah E McDonald
- Sarah Isgett
- Sarah Moore
- Sarah Redl
- Sarah Stabler
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- Sarah Tubiana
- Saye Khoo
- Scott Pharand
- Sebastien Preau
- Segolène Greffe
- Seán Keating
- Shahdattul Mawarni Taib
- Shaikh Sharjeel
- Shaminee Veeran
- Sharma Keshav
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- Shiranee Sriskandan
- Shirin Tabrizi
- Shirley Sarfo-Mensah
- Shoban Raj Vasudayan
- Shona C Moore
- Sia Loong Tonnii
- Sim Choon Ean
- Simon Bessis
- Simon Forsyth
- Simon-Djamel Thiberville
- Siri Goepel
- Siti Nurul Ridzuan
- Siti Rohani Yakop
- Siti Zubaidah Othman
- Sivanesen Anthonidass
- Sobia Masood
- Sofia Cardoso
- Soizic Le Mestre
- Sophie Halpin
- Sophie Mahy
- Srinivas Murthy
- Stanislas Rebaudet
- Stella Rousset
- Stephanie Roberts
- Stephanie Yerkovich
- Stephen R Knight
- Steve Webb
- Stéphane Jaureguiberry
- Stéphane Lasry
- Stéphane Sallaberry
- Stéphanie Cousse
- Stéphanie Fry
- Subhash Acharya
- Sue Smith
- Suhaila Abdul Wahab
- Surain Raaj Thurai
- Suresh Kumar Chidambaram
- Sushil Khanal
- Suvintheran Thangavelu
- Swosti Joshi
- Syamin Asyraf Shahidan
- Sybille Bevilcaqua
- Sylvain Diamantis
- Sylvie Behilill
- Sylvie LeGac
- Sylvie Lion-Daolio
- Sylvie Van Der Werf
- Sze Kye Teoh
- Séverine Ansart
- Tae Song
- Tahira Jamal Mohamed
- Tala Al-Dabbous
- Tan Pei Wen
- Tatiana Fonseca
- Teck Fung Wong
- Teresa Lawrence
- Thalha Rashan
- Tharmini Ravi
- Thavamany Kaleesvran
- Thibault Chiarabini
- Thierry Carmoi
- Thierry Mazzoni
- Thomas Flament
- Thomas Guimard
- Thomas Maitre
- Thomas Perpoint
- Thushan de Silva
- Théo Treoux
- Tiago Isidoro
- Tiffany Trouillon
- Timo Brandenburger
- Timothy M. Uyeki
- Ting Soo Chow
- Tiphaine Goulenok
- Todd C Lee
- Todd Karsies
- Tom Drake
- Tom Fletcher
- Tom Solomon
- Tony Trapani
- Tristan Gigante
- Tze Vee Soh
- Tze Yuan Tee
- Tânia Sequeira
- Valentine Campana
- Valeria Balan
- Valla Sahraei
- Valérie Gaborieau
- Valérie Garrait
- Valérie Gissot
- Vanessa Sancho-Shimizu
- Vanina Meysonnier
- Ventzislava Petrov-Sanchez
- Victor Fomin
- Victoria Manda
- Victoria Shaw
- Vilmaris Quinones-Cardona
- Vincent Dinot
- Vincent Dubée
- Vincent Enouf
- Vincent Langlois
- Vincent Le Moing
- Vincent Peigne
- Vincent Pestre
- Vincent Thibault
- Vinod Kumar
- Vinothini Krishnan
- Véronique Lemee
- Víctor Quirós González
- Waasila Jassat
- Walter Picard
- Wei Han Hoh
- Wei Shen Lim
- Wendy S. Barclay
- William A. Paxton
- William Dechert
- William Greenhalf
- Wilna Oosthuyzen
- Wim Dieperink
- Xavier Duval
- Xin Ci Wong
- Yael Dishon
- Yan Chyi Tan
- Yaseen Arabi
- Yasmin Gani
- Yazdan Yazdanpanah
- Yen Tsen Saw
- Yew Sing Wong
- Yi Bin Ho
- Yi Lin Lee
- Ymkje Stienstra
- Yoan Lavie-Badie
- Younes Ait Tamlihat
- Younes Kerroumi
- Yun Sii Ing
- Yusing Gu
- Yvelynne Kelly
- Yves Levy
- Zhang Duan Tham
- Zul Amali Kamaruddin
- Zulfiqar Sandhu
- Publication venue
- 'BMJ'
- Publication date
- 01/10/2022
- Field of study
Background The impact of the COVID-19 pandemic on paediatric populations varied between high-income countries (HICs) versus low-income to middle-income countries (LMICs). We sought to investigate differences in paediatric clinical outcomes and identify factors contributing to disparity between countries.Methods The International Severe Acute Respiratory and Emerging Infections Consortium (ISARIC) COVID-19 database was queried to include children under 19 years of age admitted to hospital from January 2020 to April 2021 with suspected or confirmed COVID-19 diagnosis. Univariate and multivariable analysis of contributing factors for mortality were assessed by country group (HICs vs LMICs) as defined by the World Bank criteria.Results A total of 12 860 children (3819 from 21 HICs and 9041 from 15 LMICs) participated in this study. Of these, 8961 were laboratory-confirmed and 3899 suspected COVID-19 cases. About 52% of LMICs children were black, and more than 40% were infants and adolescent. Overall in-hospital mortality rate (95% CI) was 3.3% [=(3.0% to 3.6%), higher in LMICs than HICs (4.0% (3.6% to 4.4%) and 1.7% (1.3% to 2.1%), respectively). There were significant differences between country income groups in intervention profile, with higher use of antibiotics, antivirals, corticosteroids, prone positioning, high flow nasal cannula, non-invasive and invasive mechanical ventilation in HICs. Out of the 439 mechanically ventilated children, mortality occurred in 106 (24.1%) subjects, which was higher in LMICs than HICs (89 (43.6%) vs 17 (7.2%) respectively). Pre-existing infectious comorbidities (tuberculosis and HIV) and some complications (bacterial pneumonia, acute respiratory distress syndrome and myocarditis) were significantly higher in LMICs compared with HICs. On multivariable analysis, LMIC as country income group was associated with increased risk of mortality (adjusted HR 4.73 (3.16 to 7.10)).Conclusion Mortality and morbidities were higher in LMICs than HICs, and it may be attributable to differences in patient demographics, complications and access to supportive and treatment modalities