Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

Methods speed-strength training jumpers tumbling sports category

Trampolines tumbling during exercise are important speed-strength. In this connection it is necessary to the proper distribution of special physical activity at all stages of preparation in order to achieve the highest level of manifestation of this quality in the competitive period.В прыжках на акробатической дорожке при выполнении упражнений большое значение имеют скоростно-силовые качества. В связи с этим возникает необходимость правильного распределения специальной физической нагрузки на всех этапах подготовки с целью достижения наибольшего проявления уровня данного качества в соревновательный период

Evaluation of major parties prospects of young athletes in akrabatike

Development of basic indicators of model characteristics physique, motor skills and some of the features of the personality acrobats for the acquisition of compositions of women's acrobatic groups at the stage of specialized training, which allows to increase the effectiveness of the system of preparation of athletes, specializing in one or another form of sports acrobatics.Разработаны основные показатели модельных характеристик телосложения, моторики и некоторых свойств личности акробаток для комплектования составов женских акробатических групп на этапе специализированной подготовки, что позволяет повысить эффективность всей системы подготовки спортсменок, специализирующихся в том или ином виде спортивной акробатики