250 research outputs found
SB55-11/12: Recognition of Jim O\u27Day
SB55-11/12: Recognition of Jim O\u27Day. This resolution passed with unanimous consent during the April 25, 2012 meeting of the Associated Students of the University of Montana (ASUM)
Requirements analysis document
This document details the purpose, features, and expected interfaces for the complete EXCELERATE WP9 (Use Case D: ELIXIR framework for secure archiving, dissemination and analysis of human access-controlled data). It outlines the tasks the system will perform, the constraints under which it operates, and how it reacts in certain circumstances. This document is intended for stakeholders, designers and developers as well as users of the system, and derives from a joint analysis carried out with these groups
Restricting sugar or carbohydrate intake does not impact physical activity level or energy intake over 24 h despite changes in substrate use : A randomised crossover study in healthy men and women
Purpose
To determine the effects of dietary sugar or carbohydrate restriction on physical activity energy expenditure, energy intake, and physiological outcomes across 24 h.
Methods
In a randomized, open-label crossover design, twenty-five healthy men (n = 10) and women (n = 15) consumed three diets over a 24-h period: moderate carbohydrate and sugar content (MODSUG = 50% carbohydrate [20% sugars], 15% protein, 35% fat); low sugar content (LOWSUG = 50% carbohydrate [< 5% sugars], 15% protein, 35% fat); and low carbohydrate content (LOWCHO = 8% carbohydrate [< 5% sugars], 15% protein, 77% fat). Postprandial metabolic responses to a prescribed breakfast (20% EI) were monitored under laboratory conditions before an ad libitum test lunch, with subsequent diet and physical activity monitoring under free-living conditions until blood sample collection the following morning.
Results
The MODSUG, LOWSUG and LOWCHO diets resulted in similar mean [95%CI] rates of both physical activity energy expenditure (771 [624, 919] vs. 677 [565, 789] vs. 802 [614, 991] kcal·d−1; p = 0.29] and energy intake (2071 [1794, 2347] vs. 2195 [1918, 2473] vs. 2194 [1890, 2498] kcal·d−1; P = 0.34), respectively. The LOWCHO condition elicited the lowest glycaemic and insulinaemic responses to breakfast (P < 0.01) but the highest 24-h increase in LDL-cholesterol concentrations (P < 0.001), with no differences between the MODSUG and LOWSUG treatments. Leptin concentrations decreased over 24-h of consuming LOWCHO relative to LOWSUG (p < 0.01).
Conclusion
When energy density is controlled for, restricting either sugar or total dietary carbohydrate does not modulate physical activity level or energy intake over a 24-h period (~ 19-h free-living) despite substantial metabolic changes.
Clinical trials registration ID
NCT03509610, https://clinicaltrials.gov/show/NCT0350961
The Vehicle, Spring 1996
Vol. 37, No. 2
Table of Contents
Poetry
AnyoneKeith Owenspage 2
Of Words and WidgetsJ. Dylan McNeillpage 3
HouseplantsPeter W. Katespage 4
IcarusJeff Vande Zandepage 5
UntitledPatrick F. Kellypage 7
CommuteWhitty Whitesellpage 8
During Graduate SchoolJeff Vande Zandepage 9
NeuteredJason S. Loguepage 10
Bitter WritingJ. Dylan McNeillpage 11
Song to Unknown SoldiersM. Olatoye Bayieupage 12
SoftAmy Haynespage 13
Mother\u27s Crossword PuzzlesMatthew J. Nelsonpage 14
Prose
Cold ShowerMatt Parkspage 17
Your Title HereKeith Owenspage 20
Biographies
Authorspage 27https://thekeep.eiu.edu/vehicle/1067/thumbnail.jp
Raman Study of Layered Breathing Kagome Lattice Semiconductor Nb3Cl8
Niobium chloride (Nb3Cl8) is a layered 2D semiconducting material with many
exotic properties including a breathing kagome lattice, a topological flat band
in its band structure, and a crystal structure that undergoes a structural and
magnetic phase transition at temperatures below 90 K. Despite being a
remarkable material with fascinating new physics, the understanding of its
phonon properties is at its infancy. In this study, we investigate the phonon
dynamics of Nb3Cl8 in bulk and few layer flakes using polarized Raman
spectroscopy and density functional theory (DFT) analysis to determine the
material's vibrational modes, as well as their symmetrical representations and
atomic displacements. We experimentally resolved 12 phonon modes, 5 of which
are A1g modes while the remaining 7 are Eg modes, which is in strong agreement
with our DFT calculation. Layer-dependent results suggest that the Raman peak
positions are mostly insensitive to changes in layer thickness, while peak
intensity and FWHM are affected. Raman measurements as a function of excitation
wavelength (473-785 nm) show a significant increase of the peak intensities
when using a 473 nm excitation source, suggesting a near resonant condition.
Temperature-dependent Raman experiments carried out above and below the
transition temperature did not show any change in the symmetries of the phonon
modes, suggesting that the structural phase transition is likely from the high
temperature P3m1 phase to the low-temperature R3m phase. Magneto-Raman
measurements carried out at 140 and 2 K between -2 to 2 T show that the Raman
modes are not magnetically coupled. Overall, our study presented here
significantly advances the fundamental understanding of layered Nb3Cl8 material
which can be further exploited for future applications.Comment: 18 pages, 8 figures, 1 tabl
Effect of Plain Versus Sugar-Sweetened Breakfast on Energy Balance and Metabolic Health : A Randomized Crossover Trial
We would like to thank Pippa Heath for her help with randomization, our participants, and Dr. Graham Horgan for statistical advice. Funding Information Economic and Social Research Council. Grant Number: ES/J50015X/1 Biotechnology and Biological Sciences Research Council (BBSRC) GlaxoSmithKline Lucozade Ribena Suntory Kellogg’s Nestlé PepsiCo Sugar Nutrition UK Danone Baby Nutrition the Alpro Foundation Kellogg Europe Unilever Volac International The Collagen Research Institute British Summer FruitsPeer reviewedPublisher PD
Observation of flat and weakly dispersing bands in a van der Waals semiconductor Nb3Br8 with breathing kagome lattice
Niobium halides, Nb3X8 (X = Cl,Br,I), which are predicted two-dimensional
magnets, have recently gotten attention due to their breathing kagome geometry.
Here, we have studied the electronic structure of Nb3Br8 by using
angle-resolved photoemission spectroscopy (ARPES) and first-principles
calculations. ARPES results depict the presence of multiple flat and weakly
dispersing bands. These bands are well explained by the theoretical
calculations, which show they have Nb d character indicating their origination
from the Nb atoms forming the breathing kagome plane. This van der Waals
material can be easily thinned down via mechanical exfoliation to the ultrathin
limit and such ultrathin samples are stable as depicted from the time-dependent
Raman spectroscopy measurements at room temperature. These results demonstrate
that Nb3Br8 is an excellent material not only for studying breathing kagome
induced flat band physics and its connection with magnetism, but also for
heterostructure fabrication for application purposes.Comment: 24 pages, 12 figures, Supplemental Material include
Haloes gone MAD: The Halo-Finder Comparison Project
[abridged] We present a detailed comparison of fundamental dark matter halo
properties retrieved by a substantial number of different halo finders. These
codes span a wide range of techniques including friends-of-friends (FOF),
spherical-overdensity (SO) and phase-space based algorithms. We further
introduce a robust (and publicly available) suite of test scenarios that allows
halo finder developers to compare the performance of their codes against those
presented here. This set includes mock haloes containing various levels and
distributions of substructure at a range of resolutions as well as a
cosmological simulation of the large-scale structure of the universe. All the
halo finding codes tested could successfully recover the spatial location of
our mock haloes. They further returned lists of particles (potentially)
belonging to the object that led to coinciding values for the maximum of the
circular velocity profile and the radius where it is reached. All the finders
based in configuration space struggled to recover substructure that was located
close to the centre of the host halo and the radial dependence of the mass
recovered varies from finder to finder. Those finders based in phase space
could resolve central substructure although they found difficulties in
accurately recovering its properties. Via a resolution study we found that most
of the finders could not reliably recover substructure containing fewer than
30-40 particles. However, also here the phase space finders excelled by
resolving substructure down to 10-20 particles. By comparing the halo finders
using a high resolution cosmological volume we found that they agree remarkably
well on fundamental properties of astrophysical significance (e.g. mass,
position, velocity, and peak of the rotation curve).Comment: 27 interesting pages, 20 beautiful figures, and 4 informative tables
accepted for publication in MNRAS. The high-resolution version of the paper
as well as all the test cases and analysis can be found at the web site
http://popia.ft.uam.es/HaloesGoingMA
Aptamer-based multiplexed proteomic technology for biomarker discovery
Interrogation of the human proteome in a highly multiplexed and efficient manner remains a coveted and challenging goal in biology. We present a new aptamer-based proteomic technology for biomarker discovery capable of simultaneously measuring thousands of proteins from small sample volumes (15 [mu]L of serum or plasma). Our current assay allows us to measure ~800 proteins with very low limits of detection (1 pM average), 7 logs of overall dynamic range, and 5% average coefficient of variation. This technology is enabled by a new generation of aptamers that contain chemically modified nucleotides, which greatly expand the physicochemical diversity of the large randomized nucleic acid libraries from which the aptamers are selected. Proteins in complex matrices such as plasma are measured with a process that transforms a signature of protein concentrations into a corresponding DNA aptamer concentration signature, which is then quantified with a DNA microarray. In essence, our assay takes advantage of the dual nature of aptamers as both folded binding entities with defined shapes and unique sequences recognizable by specific hybridization probes. To demonstrate the utility of our proteomics biomarker discovery technology, we applied it to a clinical study of chronic kidney disease (CKD). We identified two well known CKD biomarkers as well as an additional 58 potential CKD biomarkers. These results demonstrate the potential utility of our technology to discover unique protein signatures characteristic of various disease states. More generally, we describe a versatile and powerful tool that allows large-scale comparison of proteome profiles among discrete populations. This unbiased and highly multiplexed search engine will enable the discovery of novel biomarkers in a manner that is unencumbered by our incomplete knowledge of biology, thereby helping to advance the next generation of evidence-based medicine
Informing the Design of Privacy-Empowering Tools for the Connected Home
Connected devices in the home represent a potentially grave new privacy
threat due to their unfettered access to the most personal spaces in people's
lives. Prior work has shown that despite concerns about such devices, people
often lack sufficient awareness, understanding, or means of taking effective
action. To explore the potential for new tools that support such needs directly
we developed Aretha, a privacy assistant technology probe that combines a
network disaggregator, personal tutor, and firewall, to empower end-users with
both the knowledge and mechanisms to control disclosures from their homes. We
deployed Aretha in three households over six weeks, with the aim of
understanding how this combination of capabilities might enable users to gain
awareness of data disclosures by their devices, form educated privacy
preferences, and to block unwanted data flows. The probe, with its novel
affordances-and its limitations-prompted users to co-adapt, finding new control
mechanisms and suggesting new approaches to address the challenge of regaining
privacy in the connected home.Comment: 10 pages, 2 figures. To appear in the Proceedings of the 2020 CHI
Conference on Human Factors in Computing Systems (CHI '20
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