Generation OnlyFans: Examining the Effects of Raunch Culture on Depression via Social Media Use and Social Comparisons

Raunch culture is a term describing the promotion of overtly sexual representations of women. This concept may provide people opportunities to engage in positive social comparisons, but also negative social comparisons. As such, this concept could also relate to the phenomenology of depression in women. In an attempt to further investigate the effects of raunch culture, this study examined relationships between raunch culture, depression, and social media use in undergraduate students. Participants (N = 199) from a moderately-sized university in the Midwest completed measures of raunch culture, depression, social comparison, and social media use via an online platform. Primary hypotheses centered around the impact of raunch culture on depressive symptoms, as well as other variables such as social comparison and social media behaviors and their involvement regarding the relationship between endorsement of raunch culture and depression. Findings suggest that students with greater depressive symptoms were more likely to be accepting of behaviors associated with raunch culture, and that this effect may be more prominent in women. Results also indicate that raunch culture may be associated with an unfolding pathway, wherein endorsement of these features is associated with more intense consumption of social media, which in turn can lead to higher rates of social comparison and ultimately affect depressive symptoms. Future research may benefit from examining raunch culture and social media involvement in the context of other important psychosocial variables

Hardness Assurance for Total Dose and Dose Rate Testing of a State-of-the-Art Off-Shore 32 nm SOI CMOS Processor

No abstract availabl

Heat Kernels on Riemannian Polyhedra and Heat Flows into NPC Manifolds

We extend the results of Eell-Sampson to show that for a continuous initial map, f, with bounded pointwise energy from a flat, compact, admissible polyhedron to a smooth compact Riemannian manifold with non-positive sectional curvature, there exists a heat flow beginning at f that converges uniformly and in energy to a harmonic map. We show that this heat flow is in $C^{1+\alpha,1+\beta}$, $\alpha, \beta>0$, on open sets bounded away from the (n-2)-skeleton, satisfies a natural balancing condition on the (n-1)-skeleton, and solves the harmonic map heat flow equation pointwise on the interior of top-dimensional simplexes. We develop Gaussian-type estimates for the gradient of heat kernel on a flat, compact, admissible polyhedron, and methods to address existence and regularity of partial differential equations on admissible polyhedra

ReHabgame: A non-immersive virtual reality rehabilitation system with applications in neuroscience

This paper proposes the use of a non-immersive virtual reality rehabilitation system ”ReHabgame” developed using Microsoft KinectT M and the ThalmicT M Labs Myo gesture control armband. The ReHabgame was developed based on two third-person video games that provide a feasible possibility of assessing postural control and functional reach tests. It accurately quantifies specific postural control mechanisms including timed standing balance, functional reach tests using real-time anatomical landmark orientation, joint velocity, and acceleration while end trajectories were calculated using an inverse kinematics algorithm. The game was designed to help patients with neurological impairment to be subjected to physiotherapy activity and practice postures of daily activities. The subjective experience of the ReHabgame was studied through the development of an Engagement Questionnaire (EQ) for qualitative, quantitative and Rasch model. The Monte-Carlo Tree Search (MCTS) and Random object (ROG) generator algorithms were used to adapt the physical and gameplay intensity in the ReHabgame based on the Motor Assessment Scale (MAS) and Hierarchical Scoring System (HSS). Rasch analysis was conducted to assess the psychometric characteristics of the ReHabgame and to identify if these are any misfitting items in the game. Rasch rating scale model (RSM) was used to assess the engagement of players in the ReHabgame and evaluate the effectiveness and attractiveness of the game. The results showed that the scales assessing the rehabilitation process met Rasch expectations of reliability, and unidimensionality. Infit and outfit mean squares values are in the range of (0.68 − 1.52) for all considered 16 items. The Root Mean Square Residual (RMSR) and the person separation reliability were acceptable. The item/person map showed that the persons and items were clustered symmetrically

A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice

Acetaminophen (APAP) overdoses are of major clinical concern. Growing evidence underlines a pathogenic contribution of sterile postinjury inflammation in APAP‐induced acute liver injury (APAP‐ALI) and justifies development of anti‐inflammatory therapies with therapeutic efficacy beyond the therapeutic window of the only current treatment option, N‐acetylcysteine (NAC). The inflammatory mediator, high mobility group box 1 (HMGB1), is a key regulator of a range of liver injury conditions and is elevated in clinical and preclinical APAP‐ALI. The anti‐HMGB1 antibody (m2G7) is therapeutically beneficial in multiple inflammatory conditions, and anti‐HMGB1 polyclonal antibody treatment improves survival in a model of APAP‐ALI. Herein, we developed and investigated the therapeutic efficacy of a partly humanized anti‐HMGB1 monoclonal antibody (mAb; h2G7) and identified its mechanism of action in preclinical APAP‐ALI. The mouse anti‐HMGB1 mAb (m2G7) was partly humanized (h2G7) by merging variable domains of m2G7 with human antibody‐Fc backbones. Effector function‐deficient variants of h2G7 were assessed in comparison with h2G7 in vitro and in preclinical APAP‐ALI. h2G7 retained identical antigen specificity and comparable affinity as m2G7. 2G7 treatments significantly attenuated APAP‐induced serum elevations of alanine aminotransferase and microRNA‐122 and completely abrogated markers of APAP‐induced inflammation (tumor necrosis factor, monocyte chemoattractant protein 1, and chemokine [C‐X‐C motif] ligand 1) with prolonged therapeutic efficacy as compared to NAC. Removal of complement and/or Fc receptor binding did not affect h2G7 efficacy. Conclusion: This is the first report describing the generation of a partly humanized HMGB1‐neutralizing antibody with validated therapeutic efficacy and with a prolonged therapeutic window, as compared to NAC, in APAP‐ALI. The therapeutic effect was mediated by HMGB1 neutralization and attenuation of postinjury inflammation. These results represent important progress toward clinical implementation of HMGB1‐specific therapy as a means to treat APAP‐ALI and other inflammatory conditions. (Hepatology 2016;64:1699‐1710)

Interacting with functional languages

Functional languages are mathematically pure, and easier to reason about than their imperative rivals. Because of this, they are an attractive paradigm of programming. They allow programmers to express complex algorithms in a declarative manner, resulting in powerful programs that are also well written. Good interaction with users is important for programs which are to be used for real applications. This normally involves creating a user interface using devices such as menus, buttons and scrollbars. It is now increasingly common for the interface of programs to be developed using specialised tools allowing a faster development cycle, with less programming involved. In the past, pure functional languages have been poor at creating graphical user interfaces resulting in good applications with poor interfaces. This is due to the mixing of the user's world which involves complex multi-level interactions, with the functional world which has a single threaded state. This is not a very good abstraction of the world to interact with. When the traits of the user's world are introduced into the functional world it is found that the purity of the functional world is compromised, and the clean declarative style of functional programming is lost. If the user interaction is separated from the functional program, allowing users to communicate with functional programs using external interface programs, it is possible to preserve the natural simplicity of the functional world. This would also allow programmers to take advantage of user interface development tools. I look at current solutions for performing input and output from functional languages, with particular reference to the Monadic I/O style which is currently gaining popularity. I then present a scheme where I have deliberately separated interaction from functionality, allowing functional programmers to build programs that interact with the "Real World", with less interference of the real world into the pure environment within the functional program

The regulation of television sports broadcasting: a comparative analysis

Based on seven different sports broadcasting markets (Australia, Brazil, Italy, India, South Africa, United Kingdom and the United States), this article provides a comparative analysis of the regulation of television sports broadcasting. The article examines how contrasting perspectives on television and sport – economic and sociocultural – have been reflected in two main approaches to the regulation of sports broadcasting, namely competition law and major events legislation. The results of this analysis suggest that in many cases, the balance between commerce and culture in sports broadcasting has shifted too far in favour of the commercial interests of dominant pay-TV operators and sports organisations. Here, the case is made for the pursuit of an approach to sports broadcasting regulation that seeks to balance the commercial priorities of broadcasters and sports organisations with the wider sociocultural benefits citizens gain from freeto- air sports broadcasting

Measurement of the Total Active 8B Solar Neutrino Flux at the Sudbury Neutrino Observatory with Enhanced Neutral Current Sensitivity

The Sudbury Neutrino Observatory (SNO) has precisely determined the total active (nu_x) 8B solar neutrino flux without assumptions about the energy dependence of the nu_e survival probability. The measurements were made with dissolved NaCl in the heavy water to enhance the sensitivity and signature for neutral-current interactions. The flux is found to be 5.21 +/- 0.27 (stat) +/- 0.38 (syst) x10^6 cm^{-2}s^{-1}, in agreement with previous measurements and standard solar models. A global analysis of these and other solar and reactor neutrino results yields Delta m^{2} = 7.1^{+1.2}_{-0.6}x10^{-5} ev^2 and theta = 32.5^{+2.4}_{-2.3} degrees. Maximal mixing is rejected at the equivalent of 5.4 standard deviations.Comment: Submitted to Phys. Rev. Let

A radium assay technique using hydrous titanium oxide adsorbent for the Sudbury Neutrino Observatory

As photodisintegration of deuterons mimics the disintegration of deuterons by neutrinos, the accurate measurement of the radioactivity from thorium and uranium decay chains in the heavy water in the Sudbury Neutrino Observatory (SNO) is essential for the determination of the total solar neutrino flux. A radium assay technique of the required sensitivity is described that uses hydrous titanium oxide adsorbent on a filtration membrane together with a beta-alpha delayed coincidence counting system. For a 200 tonne assay the detection limit for 232Th is a concentration of 3 x 10^(-16) g Th/g water and for 238U of 3 x 10^(-16) g U/g water. Results of assays of both the heavy and light water carried out during the first two years of data collection of SNO are presented.Comment: 12 pages, 4 figure

Searches For High-Frequency Variations In The B-8 Solar Neutrino Flux At The Sudbury Neutrino Observatory

We have performed three searches for high-frequency signals in the solar neutrino flux measured by the Sudbury Neutrino Observatory, motivated by the possibility that solar g-mode oscillations could affect the production or propagation of solar B-8 neutrinos. The first search looked for any significant peak in the frequency range 1-144 day(-1), with a sensitivity to sinusoidal signals with amplitudes of 12% or greater. The second search focused on regions in which g-mode signals have been claimed by experiments aboard the Solar and Heliospheric Observatory satellite, and was sensitive to signals with amplitudes of 10% or greater. The third search looked for extra power across the entire frequency band. No statistically significant signal was detected in any of the three searches.Natural Sciences and Engineering Research Council, CanadaIndustry Canada, CanadaNational Research Council, CanadaNorthern Ontario Heritage Fund, CanadaAtomic Energy of Canada, Ltd., CanadaOntario Power Generation, CanadaHigh Performance Computing Virtual Laboratory, CanadaCanada Foundation for InnovationDept. of Energy, USNational Energy Research Scientific Computing Center, USScience and Technologies Facilities Council, UKAstronom