The art of living\u27: The aesthetics of everyday life in Dorothy Canfield Fisher\u27s novels

In 1924, Dorothy Canfield Fisher (1879-1958) wrote, I have always conceived of everyday life as needing very much the sort of constant effort at composition--that is shapeliness, elimination of unnecessary details, choice of details--as any other work of art. This quotation is the epigraph to my study of five of Fisher\u27s early novels because it reveals a central theme of her fiction: that art is the creation of a daily life that successfully negotiates the problems of living (Fisher\u27s phrase) that plague modern America. The five novels that I analyze--The Squirrel-Cage (1912), The Bent Twig (1915), The Brimming Cup (1921), The Home-maker (1924) and The Deepening Stream (1930)--show that Fisher defines these problems as finding meaningful work and creating sustaining marriages and family lives. Her protagonists\u27 solutions to these problems comprise an art of living, a phrase Fisher uses to summarize the lessons her protagonists learn in their quests to shape their lives. As I explain in my introduction, Fisher\u27s relationship with her mother was a defining element in her artistic development. Although her mother embraced an art for art\u27s sake credo, Fisher felt that art should have a social purpose. Her fiction is rich with debates about art that reenact this split with her mother. Fisher forges a connection between two different artistic processes in her fiction: the ritualized shaping of domestic life, and the rigorous training of creating high art. Therefore, I argue that her position in American women\u27s literature is transitional because she blends two women\u27s literary traditions, regionalism and the kunstlerroman, broadening their boundaries. Throughout my study, I structure my chapters according to the domestic processes that Fisher invokes in her fiction--carpentry, gardening and sewing--illuminating how her protagonists combine these domestic processes with their musical careers. I also describe the social movements that Fisher was interested in--the Arts and Crafts Movement, the Montessori method of education, Freudian psychology and daycare--and show how they partially provide Fisher with the solutions she seeks in remodeling family life for modern America

If you build it, they may not come: Why Australian university students do not take part in outbound mobility experiences.

Universities around the world seek to internalise students to prepare them for an increasingly globalised world. Outbound mobility experiences (OMEs) are recognised as one of the most effective ways to foster independent thinking, cultural sensitivity, and a sense of 'worldmindedness'. This article takes a case study from an Australian university and explores efforts to increase student participation rates in OMEs

Assisting After Disaster: A Volunteer Management and Donations Management Training

Stakeholders in Mississippi perceived that Extension could lead volunteer management and donations management after a natural disaster. In response, Mississippi State University Extension professionals developed a training on volunteer management and donations management to supplement the existing Incident Management System/Incident Command System (ICS) curriculum. The training includes education on connecting volunteer management and donations management to local emergency planning, managing volunteers, managing goods and monetary donations, operating within ICS, and developing relationships between volunteer organizations and partners. The training has been pilot tested in Mississippi with promising preliminary results. Extension professionals elsewhere may benefit from similar trainings

Jafari and Transformation: A Model to enhance short-term overseas study tours

This paper promotes a reconstructed Jafari (1987) tourism model as a framework to understand the various components of the student and staff travel experience while participating in an outbound mobility experience (OME), especially short-term overseas study trips. Working through each of the components of the Jafari model allows recognition of the changing needs and requirements of both students and staff throughout an OME and the tensions that accompany this relationship

The inter-relationship of adolescent unhappiness and parental mental distress

Purpose Substantial evidence supports the hypothesis that parental well-being impacts upon child well-being and that this relationship is bidirectional. Here we explore how, in a large, nationally representative sample, both parents' mental distress relates over time to each other's mental distress and to their adolescent child's unhappiness, and vice versa. Methods Analyses were conducted using data from waves one to five (2009/10–2014/15) of Understanding Society, the UK Household Longitudinal Study. Understanding Society collects data on adults' mental distress (General Health Questionnaire), and on youths' (age: 10–15 years) unhappiness in relation to their school work, appearance, family, friends, school, and life as a whole. We use repeated-measures structural equation models to investigate the reciprocal relationships between both parents' distress and their child's unhappiness, using both longitudinal cross-lagged and nonrecursive contemporaneous specifications. The analytic sample is 1,883 triads (adolescent child, mother, and father) with data at two or more consecutive time points. Analyses are stratified by adolescent gender. Results Our results show that parental mental distress predicts unhappiness of girls but not that of boys. Reciprocal associations of maternal and paternal mental distress are evident in families with an adolescent daughter. Unhappiness of adolescents does not predict their parents' mental distress. Results are similar whether examined contemporaneously or over time. Conclusions Our findings support the suggestion that the family should be considered as a dynamic system, for instance when planning clinical interventions. This is particularly pertinent in families with an adolescent daughter present

Randomised controlled trial of the Community Navigator programme to reduce loneliness and depression for adults with treatment-resistant depression in secondary community mental health services: trial protocol

BACKGROUND: New treatments are needed for people with treatment-resistant depression (TRD), who do not benefit from anti-depressants and many of whom do not recover fully with psychological treatments. The Community Navigator programme was co-produced with service users and practitioners. It is a novel social intervention which aims to reduce loneliness and thus improve health outcomes for people with TRD. Participants receive up to 10 individual meetings with a Community Navigator, who helps them to map their social world and set and enact goals to enhance their social connections and reduce loneliness. Participants may also access group meet-ups with others in the programme every 2 months, and may be offered modest financial support to enable activities to support social connections. METHODS: A researcher-blind, multi-site, 1:1 randomised controlled trial with N = 306 participants will test the effectiveness of the Community Navigator programme for people with TRD in secondary community mental health teams (CMHTs). Our primary hypothesis is that people who are offered the Community Navigator programme as an addition to usual CMHT care will be less depressed, assessed using the PHQ-9 self-report measure, at 8-month, end-of-treatment follow-up, compared to a control group receiving usual CMHT care and a booklet with information about local social groups and activities. We will follow participants up at end-of-treatment and at 14 months, 6 months after end-of-treatment follow-up. Secondary outcomes include the following: loneliness, anxiety, personal recovery, self-efficacy, social network, social identities. We will collect data about health-related quality of life and service use to investigate the cost-effectiveness of the Community Navigator programme. DISCUSSION: This trial will provide definitive evidence about the effectiveness and cost-effectiveness of the Community Navigator programme and whether it can be recommended for use in practice. The trial is due to finish in August 2025. TRIAL REGISTRATION: Prospectively registered on 8th July 2022 at: ISRCTN13205972

A solution scan of societal options to reduce transmission and spread of respiratory viruses: SARS-CoV-2 as a case study.

Societal biosecurity - measures built into everyday society to minimize risks from pests and diseases - is an important aspect of managing epidemics and pandemics. We aimed to identify societal options for reducing the transmission and spread of respiratory viruses. We used SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) as a case study to meet the immediate need to manage the COVID-19 pandemic and eventually transition to more normal societal conditions, and to catalog options for managing similar pandemics in the future. We used a 'solution scanning' approach. We read the literature; consulted psychology, public health, medical, and solution scanning experts; crowd-sourced options using social media; and collated comments on a preprint. Here, we present a list of 519 possible measures to reduce SARS-CoV-2 transmission and spread. We provide a long list of options for policymakers and businesses to consider when designing biosecurity plans to combat SARS-CoV-2 and similar pathogens in the future. We also developed an online application to help with this process. We encourage testing of actions, documentation of outcomes, revisions to the current list, and the addition of further options

Responses of Southern Ocean seafloor habitats and communities to global and local drivers of change

Knowledge of life on the Southern Ocean seafloor has substantially grown since the beginning of this century with increasing ship-based surveys and regular monitoring sites, new technologies and greatly enhanced data sharing. However, seafloor habitats and their communities exhibit high spatial variability and heterogeneity that challenges the way in which we assess the state of the Southern Ocean benthos on larger scales. The Antarctic shelf is rich in diversity compared with deeper water areas, important for storing carbon (“blue carbon”) and provides habitat for commercial fish species. In this paper, we focus on the seafloor habitats of the Antarctic shelf, which are vulnerable to drivers of change including increasing ocean temperatures, iceberg scour, sea ice melt, ocean acidification, fishing pressures, pollution and non-indigenous species. Some of the most vulnerable areas include the West Antarctic Peninsula, which is experiencing rapid regional warming and increased iceberg-scouring, subantarctic islands and tourist destinations where human activities and environmental conditions increase the potential for the establishment of non-indigenous species and active fishing areas around South Georgia, Heard and MacDonald Islands. Vulnerable species include those in areas of regional warming with low thermal tolerance, calcifying species susceptible to increasing ocean acidity as well as slow-growing habitat-forming species that can be damaged by fishing gears e.g., sponges, bryozoan, and coral species. Management regimes can protect seafloor habitats and key species from fishing activities; some areas will need more protection than others, accounting for specific traits that make species vulnerable, slow growing and long-lived species, restricted locations with optimum physiological conditions and available food, and restricted distributions of rare species. Ecosystem-based management practices and long-term, highly protected areas may be the most effective tools in the preservation of vulnerable seafloor habitats. Here, we focus on outlining seafloor responses to drivers of change observed to date and projections for the future. We discuss the need for action to preserve seafloor habitats under climate change, fishing pressures and other anthropogenic impacts

Randomised controlled trial of the Community Navigator programme to reduce loneliness and depression for adults with treatment-resistant depression in secondary community mental health services : trial protocol

BACKGROUND: New treatments are needed for people with treatment-resistant depression (TRD), who do not benefit from anti-depressants and many of whom do not recover fully with psychological treatments. The Community Navigator programme was co-produced with service users and practitioners. It is a novel social intervention which aims to reduce loneliness and thus improve health outcomes for people with TRD. Participants receive up to 10 individual meetings with a Community Navigator, who helps them to map their social world and set and enact goals to enhance their social connections and reduce loneliness. Participants may also access group meet-ups with others in the programme every 2 months, and may be offered modest financial support to enable activities to support social connections. METHODS: A researcher-blind, multi-site, 1:1 randomised controlled trial with N = 306 participants will test the effectiveness of the Community Navigator programme for people with TRD in secondary community mental health teams (CMHTs). Our primary hypothesis is that people who are offered the Community Navigator programme as an addition to usual CMHT care will be less depressed, assessed using the PHQ-9 self-report measure, at 8-month, end-of-treatment follow-up, compared to a control group receiving usual CMHT care and a booklet with information about local social groups and activities. We will follow participants up at end-of-treatment and at 14 months, 6 months after end-of-treatment follow-up. Secondary outcomes include the following: loneliness, anxiety, personal recovery, self-efficacy, social network, social identities. We will collect data about health-related quality of life and service use to investigate the cost-effectiveness of the Community Navigator programme. DISCUSSION: This trial will provide definitive evidence about the effectiveness and cost-effectiveness of the Community Navigator programme and whether it can be recommended for use in practice. The trial is due to finish in August 2025. TRIAL REGISTRATION: Prospectively registered on 8th July 2022 at: ISRCTN13205972

Mutations in KEOPS-Complex Genes Cause Nephrotic Syndrome with Primary Microcephaly

Galloway-Mowat syndrome (GAMOS) is an autosomal-recessive disease characterized by the combination of early-onset nephrotic syndrome (SRNS) and microcephaly with brain anomalies. Here we identified recessive mutations in OSGEP, TP53RK, TPRKB, and LAGE3, genes encoding the four subunits of the KEOPS complex, in 37 individuals from 32 families with GAMOS. CRISPR-Cas9 knockout in zebrafish and mice recapitulated the human phenotype of primary microcephaly and resulted in early lethality. Knockdown of OSGEP, TP53RK, or TPRKB inhibited cell proliferation, which human mutations did not rescue. Furthermore, knockdown of these genes impaired protein translation, caused endoplasmic reticulum stress, activated DNA-damage-response signaling, and ultimately induced apoptosis. Knockdown of OSGEP or TP53RK induced defects in the actin cytoskeleton and decreased the migration rate of human podocytes, an established intermediate phenotype of SRNS. We thus identified four new monogenic causes of GAMOS, describe a link between KEOPS function and human disease, and delineate potential pathogenic mechanisms