11 research outputs found
AQP4-IgG NMOSD, MOGAD, and double-seronegative NMOSD: is it possible to depict the antibody subtype using magnetic resonance imaging?
- Author
- Publication venue
- 'Georg Thieme Verlag KG'
- Publication date
- 01/06/2023
- Field of study
BackgroundâThere is clinical and radiological overlap among demyelinating diseases. However, their pathophysiological mechanisms are different and carry distinct prognoses and treatment demands.
ObjectiveâTo investigate magnetic resonance imaging (MRI) features of patients with myelin-oligodendrocyte glycoprotein associated disease (MOGAD), antibody against aquaporin-4(AQP-4)-immunoglobulin G-positive neuromyelitis optica spectrum disorder (AQP4-IgG NMOSD), and double-seronegative patients.
MethodsâA cross-sectional retrospective study was performed to analyze the topography and morphology of central nervous system (CNS) lesions. Two neuroradiologists consensually analyzed the brain, orbit, and spinal cord images.
ResultsâIn total, 68 patients were enrolled in the study (25 with AQP4-IgG-positive NMOSD, 28 with MOGAD, and 15 double-seronegative patients). There were differences in clinical presentation among the groups. The MOGAD group had less brain involvement (39.2%) than the NMOSD group (pâ=â0.002), mostly in the subcortical/juxtacortical, the midbrain, the middle cerebellar peduncle, and the cerebellum. Double-seronegative patients had more brain involvement (80%) with larger and tumefactive lesion morphology. In addition, double-seronegative patients showed the longest optic neuritis (pâ=â0.006), which was more prevalent in the intracranial optic nerve compartment. AQP4-IgG-positive NMOSD optic neuritis had a predominant optic-chiasm location, and brain lesions mainly affected hypothalamic regions and the postrema area (MOGAD versus AQP4-IgG-positive NMOSD, p= 0 .013). Furthermore, this group had more spinal cord lesions (78.3%), and bright spotty lesions were a paramount finding to differentiate it from MOGAD (pâ=â0.003).
ConclusionâThe pooled analysis of lesion topography, morphology, and signal intensity provides critical information to help clinicians form a timely differential diagnosis
NEOTROPICAL XENARTHRANS: a data set of occurrence of xenarthran species in the Neotropics
- Author
- Abba Agustin Manuel
- Abra Fernanda Delborgo
- Age Stefani Gabrieli
- Aguiar Erick Francisco
- Aguiar Gabriel Lima
- Akkawi Paula
- Alberici Vinicius
- Almeida Josué Santos
- Alvarez MartĂn R.
- Alves Mario Henrique
- Alves Rafael Souza Cruz
- Alves-Eigenheer Milene
- Anacleto Teresa Cristina
- Andrade-NĂșñez MarĂa JosĂ©
- Anleu Rony GarcĂa
- AraĂșjo Luciana Souza
- AraĂșjo Rodrigo Costa
- Arrabal Juan Pablo
- Arrais Ricardo Corassa
- Arroyo-Gerala Paulina
- Assis Julia Camara
- AstĂșa Diego
- Attias Nina
- Aximoff Izar
- Ayala Rodrigo
- Bager Alex
- Bailey Larissa L.
- Ballari SebastiĂĄn A.
- Barbosa Lucas Lobo
- Barcelos Daniele
- Barros MarĂlia A.S.
- Bastazini VinĂcius Augusto GalvĂŁo
- Batista Graziele Oliveira
- Bazilio SĂ©rgio
- Beca Gabrielle
- Beccato Maria Angélica Barbosa
- Beduschi JĂșlia
- BeltrĂŁo Mayara GuimarĂŁes
- BeltrĂŁo-Mendes Raone
- Benchimol MaĂra
- Benedetti Maximiliano Augusto
- BercĂȘ William
- Bernardi ItiberĂȘ
- Bernardo Luis Renato Rezende
- Bertassoni Alessandra
- Bertoldi Ariane Teixeira
- Betkowski Samuel Eurich
- Boaglio Gabriel Ivan
- Bocchiglieri Adriana
- Bogoni Juliano André
- Bonikowski Renata Twardowsky Ramalho
- Bonjorne Lilian
- Borges Luiz Henrique Medeiros
- Botelho André Luis Moura
- Bovendorp Ricardo Siqueira
- Bovo Alex Augusto Abreu
- Braga Caryne
- Braga Ricardo Miranda
- Brennand Pamella G.G.
- Brocardo Carlos R.
- Brown Danielle
- BrĂtez Evelyn Beatriz
- Bueno CecĂlia
- Burs Kathrin
- Buscariol Daiane
- Cabral Hugo
- Calouro Armando Muniz
- Camino Micaela
- Campelo Ana Kellen Nogueira
- Campos Bruno Augusto Torres Parahyba
- Canassa NathĂĄlia F.
- Candia-Gallardo Carlos
- Cantagallo Camila
- Cantero NicolĂĄs
- Carrano Eduardo
- Carreira Daiane Cristina
- Cartes Jose Luis
- Caruso Flavia
- Carvalho Danianderson Rodrigues
- Carvalho Diana LetĂcia Kruger Pacheco
- Carvalho Elildo Alves Ribeiro
- Carvalho Fernando
- Carvalho Santiago
- Casali Daniel
- Castro Ărika Paula
- Castro-Prieto Jessica
- Cavalcanti Sandra M.C.
- Cavicchioli Guilherme
- Cervini Marcelo
- Cherem Jorge José
- Chiarello Adriano Garcia
- Chinem Simonne
- Ciccia Paula Gonzalez
- Ciocheti Giordano
- Cirignoli SebastiĂĄn
- Coelho Igor Pfeifer
- Colas-Rosas Paul François
- Concone Henrique Villas Boas
- Condé Paula Alves
- Contreras-Moreno Fernando M.
- Cortez Sara
- Costa Alan Nilo
- Costa Ana RaĂssa Cunha
- Costa Francys Emanuelle
- Costa Sebastiån Andrés
- Cruz Paula
- Cullen Laury
- CĂĄceres Nilton Carlos
- D'Bastiani Elvira
- da Costa Toledo Gustavo Alvez
- da Cunha Cristina Jaques
- da Cunha Rogério Grassetto Teixeira
- da Rocha PatrĂcio Adriano
- da Rosa Oliveira Nicole
- da Silva Ferraz Daniel
- da Silva Santos Fernanda
- da Silva André Luiz Ferreira
- da Silva Fernanda Guedes
- da Silva Franciane Almeida
- da Silva Kena Ferrari Moreira
- da Silva Leonardo Henrique
- da Silva Maria Augusta Andrade
- da Silva Marina Lima
- da Silva Marina Xavier
- da Silva Murillo Prado
- da Silva Rayana Diniz
- de Abreu-JĂșnior Edson Fiedler
- de AlagĂŁo Querido Luciano Carramaschi
- de Albuquerque França Bruno Rodrigo
- de Albuquerque Anna Carolina Figueiredo
- De Albuquerque Natasha Moraes
- de Almeida Chiquito Elisandra
- de Almeida Nobre Rodrigo
- de Almeida Rodrigues Livia
- de Andrade Silva Katyucha Von Kossel
- de Andrade Layla Reis
- De Angelo Carlos
- de Assis Jardim MĂĄrcia Maria
- de Azevedo Fernanda Cavalcanti
- de Azevedo Fernando Cesar Cascelli
- de Barros Fabio Monteiro
- de Bustos Soledad
- de Campos Claudia Bueno
- de Carvalho William Douglas
- de Cassia Bianchi Rita
- de Castilho Pedro Volkmer
- de Castro Morini Maria Santina
- de Castro Ernesto B.Viveiros
- de Faria FalcĂŁo JĂ©ssica Caroline
- de Faria Oshima JĂșlia Emi
- de Faria Peres Pedro Henrique
- de Fatima Cunha Lerrane
- de Freitas Carlos Henrique
- de Gaspari JĂșnior Roque LĂĄzaro
- de Godoy Bergallo Helena
- de la Colina MarĂa Alicia
- de la Cruz Yaribeth Bravata
- de la Maza Javier
- de la Peña-Cuéllar Erika
- de la Sancha Noé U.
- de la Torre J. Antonio
- de Matos Cardoso Elizandra
- de Matos Jose Roberto
- de Mattia Denise Lidoro
- de Melo-Soares Carla Danielle
- de Miranda MourĂŁo Guilherme
- de Oliveira Gasparotto Vinicius Peron
- de Oliveira Paschoal Ana Maria
- de Oliveira Roque Fabio
- de Oliveira Anne Karoline
- de Oliveira Luiz Flamarion Barbosa
- de Oliveira MĂĄrcio Leite
- de Oliveira Tadeu Gomes
- de Paula Milton José
- de Paula Rogério Cunha
- de Pinho Fernando Ferreira
- de Sena Liana Mara Mendes
- de Sousa Luziene Conceição
- de Souza Fialho Marcos
- de Souza Laurindo Rafael
- de Souza Agnis Cristiane
- de Souza Franco Leandro
- de Tarso Zuquim Antas Paulo
- de Thoisy Benoit
- de Toledo José Julio
- Deffaci Ăngela Camila
- del Castillo Cordero Hugo Fernando
- Delsuc Frédéric
- Denkiewicz Natalia Mariana
- Desbiez Arnaud L.J.
- Devlin Allison L.
- Di Bitetti Mario S.
- Di Blanco Yamil Edgardo
- Dias Douglas Matos
- Dias JĂ©ssica Helena Mangueira
- do Prado Helena Alves
- Dornas Rubem
- dos Santos Everton LaĂs
- dos Santos Cinthya Chiva
- dos Santos Juliana Silveira
- dos Santos Manuela Vieira
- Duarte Gabriela Teixeira
- Duarte Herbert
- Duarte JosĂ© MaurĂcio Barbanti
- Dums Marcos
- DĂĄttilo Wesley
- Eaton Donald P.
- Endo Whaldener
- Esbérard Carlos Eduardo Lustosa
- Escobar Santiago
- Esperandio Isadora Beraldi
- Estrela Pedro Cordeiro
- Falconi Nereyda
- Fantacini Felipe Moreli
- Faria Deborah
- Faustino Alexandre Casagrande
- Favarini Marina Ochoa
- Favoretti JoĂŁo Paulo Pandini
- FeijĂł Anderson
- Fernandes Arthur
- Fernandes-Ferreira Hugo
- Ferraz Katia M.P.M.B.
- Ferreguetti Atilla Colombo
- Ferreira Guilherme Braga
- Ferreira Paula Modenesi
- Ferreira Scarlat Dalva
- Filho Newton Mota
- Filho Vilmar Picinatto
- Fischer Erich
- Fragoso Carlos Eduardo
- Franceschi Ingridi Camboim
- Freitas-Junior Mozart
- Friedeberg Diana B.
- Galetti Mauro
- Gallina Alberto Gonzalez
- GarcĂa-Olaechea Alvaro
- Gaspari Fernando
- Gaspari Gustavo Gabirele
- Gatica Ailin
- Gatti Andressa
- Gengler Nicholas
- Gestich Carla Cristina
- Gil Guillermo Eduardo
- Giné Gastón Andrés Fernandez
- Giovanelli JoĂŁo Gabriel Ribeiro
- Girardi Fabiane
- Giubbina Marina Furlan
- Godim Tayana
- Godoi Mauricio Neves
- Godoy Leandro Perez
- Gonsioroski Gustavo
- Gontijo Nila RĂĄssia Costa
- GonzĂĄlez Enrique
- Gonçalves Fernando
- Gonçalves Larissa Oliveira
- Gonçalves Pablo Rodrigues
- Gordo Marcelo
- Graipel MaurĂcio Eduardo
- Grangeiro Raissa Danielle Praxedes
- Grotta-Neto Francisco
- Guarderas Zoila Vega
- Guedes PatrĂcia Gonçalves
- Guenther Mariana
- Guijosa-Guadarrama Emiliano
- GuimarĂŁes Luiza Neves
- GĂłmez-Valencia Bibiana
- Hack Robson Odeli EspĂndola
- Hannibal Wellington
- Hartmann Paulo Afonso
- Henz Denison José
- Hidalgo Mircea Mihart
- Hinojosa Javier
- Hirsch André
- Hofmann Gabriel Selbach
- Honda Laura K.
- Hoogesteijn Rafael Jan
- Hufnagel Ludmila
- Hurtado Cindy Meliza
- Hurtado Rafael Reyna
- Iezzi Maria Eugenia
- Iglesias JesĂșs A.
- Jenkins Clinton N.
- Jesus Alejandro
- Jesus Anamélia Souza
- Jorge Maria LuĂsa
- JuĂĄrez Rugieri
- Kanda Claudia Zukeran
- Kasper Carlos Benhur
- Keuroghlian Alexine
- Keuroghlian-Eaton Sean
- Kindel Andreas
- Koenemann Joceleia G.
- Krauer Juan Manuel Campos
- Krepschi Victor Gasperotto
- Lacerda Ana Cristyna Reis
- Landis Mariana Bueno
- Lanna André Monnerat
- Lara Camila Clozato
- Laurito Sabrina
- Layme Viviane Maria Guedes
- Leles Bruno
- Lemos Frederico
- Leuchtenberger Caroline
- Leuzinger Lucas
- Lim Burton
- Lima Breno Campelo
- Lima Camila Silveira
- Lima Fernando
- Lima Saulo Ramos
- Lira Paula Koeler
- Lombardi Pryscilla Moura
- Lopes Alexandre Martins Costa
- Lopes Karine Galisteo Diemer
- Loughry William James
- Luciano Beatriz Fernandes Lima
- Luiz Micheli Ribeiro
- Luna CecĂlia LicariĂŁo
- Maccarini Thiago Bernardes
- Machado Ricardo Bomfim
- MagalhĂŁes Rodolfo Assis
- Maggiorini Erica Vanessa
- Magioli Marcelo
- Mangione Antonio Marcelo
- Marinho Paulo Henrique
- Marques MarinĂȘz Isaac
- Marques Rosane Vieira
- Marsh Laura K.
- Martello Felipe
- Martensen Alexandre Camargo
- MartĂnez-Lanfranco Juan A.
- MarĂĄs Gustavo A.
- Massara Rodrigo Lima
- Massocato Gabriel FĂĄvero
- Mazim FĂĄbio Dias
- McDonough Colleen
- McNab Roan
- Medeiro Akyllan Zoppi
- Medeiros Hugo Reis
- Meiga Ana Yoko Ykeuti
- Melo Carolina Depolito
- Melo Geruza Leal
- Mendes SĂ©rgio Lucena
- Mendonça Eloisa Neves
- Mendonça Luana
- Miranda FlĂĄvia Regina
- Mol Alexandra Cravino
- Montanarin Anelise
- Monteiro Miguel Coutinho Moretta
- Moraes Andreia Magro
- Moraes Marcela FiguerĂȘdo Duarte
- Morato Ronaldo Gonçalves
- Moreira Adryelle
- Moreira Danielle Oliveira
- Moreira Tainah Cruz
- Mourthe Italo
- Möcklinghoff Lydia
- Nagy-Reis Mariana Baldy
- Neto Jorge Ferreira Lima
- Neto Omar Correia
- Niebuhr Bernardo BrandĂŁo S.
- Nobre Andrezza Bellotto
- Nodari Joana Zorzal
- Noss Andrew J.
- Nunes André Valle
- NĂșñez-Regueiro Mauricio M.
- Ochoa Ana Cecilia
- Oliveira Ana Cristina Mendes
- Oliveira Bruna Gomes
- Oliveira Caetano Troncoso
- Oliveira Gabriela Schuck
- Oliveira JoĂŁo Alves
- Oliveira Marcela Alvares
- Oliveira Marcelo Juliano Rabelo
- Oliveira-Santos Luiz Gustavo Rodrigues
- Orsini Vinicius Santana
- Pacheco Julio Javier ChacĂłn
- Paglia Adriano Pereira
- Palmeira Francesca Belem Lopes
- Paolino Roberta Montanheiro
- Papi Bernardo
- Pardo Julia Martinez
- Pasqualotto Nielson
- Passamani Marcelo
- Passos Fernando C.
- Paviolo Agustin
- Pays Olivier
- Pedroni Fernando
- Pedrosa Felipe
- PedĂł Ezequiel
- Percequillo Alexandre Reis
- Pereira Maria JoĂŁo Ramos
- Pereira-Ribeiro Juliane
- Peres Carlos A.
- Perilli Miriam Lucia Lages
- Perillo Lucas Neves
- Perini Fernando Araujo
- Peroni Nivaldo
- Perovic Pablo Gaston
- Peters Felipe Bortolotto
- Pezzuti Juarez Carlos Brito
- Peña-Mondragón Juan Luis
- Pinheiro Marcell Soares
- Pinheiro Paula Fabiana
- Pinto Fredy Ramirez
- Piovezan Ubiratan
- Polisar John
- Pontes Antonio Rossano Mendes
- Preuss Gabriel
- PĂ©rez Rodrigo RaĂșl LeĂłn
- PĂ©rez-Garduza Freddy
- Queirolo Diego
- Quintilham Lucas
- Quiroga VerĂłnica Andrea
- Ramalho Emiliano Esterci
- Ramirez Sixto FernĂĄndez
- Ramos Daniella Leal
- Rampim Lilian Elaine
- RamĂrez JosĂ© Fernando Moreira
- Regolin André Luis
- Renaud Pierre Cyril
- Reppucci Juan
- Retta LucĂa MartĂnez
- Ribeiro Igor Kintopp
- Ribeiro Juliana Fernandes
- Ribeiro Ludmilla Oliveira
- Ribeiro Milton Cezar
- Ribeiro OtĂĄvio Santi
- Ribeiro Paulo
- Rivadeneira Edgar Federico
- Rivero Marina
- Rocha Alessandro
- Rocha Ednaldo CĂąndido
- Rocha Fabiana Lopes
- Rodrigues FlĂĄvio Henrique GuimarĂŁes
- Rodrigues Thiago Ferreira
- Rojano Cesar
- Rojas Bonzi Viviana B.
- Rolim Samir Gonçalves
- Rosa Clarissa
- Rudolf Juan Carlos
- Salvador Carlos Henrique
- Sampaio Ricardo
- Sana Denis Alessio
- SantamarĂa Silvia Benito
- Santana Gindomar Gomes
- Santiago Pablo Gerardo FernĂĄndez
- Santos Bruna Silva
- Santos BrĂĄulio A.
- Santos Cyntia
- Santos Eduardo Marques
- Santos Filipe Pereira Rego
- Santos Paloma Marques
- Santos-Filho Manoel
- Sartorello Leonardo
- Sartorello Ricardo
- Schaub Roxane
- Schuchmann Karl L.
- Secco Helio
- Seibert Jardel BrandĂŁo
- Setz Eleonore Zulnara Freire
- Severo Magnus Machado
- Silva ClĂĄudia Regina
- Silva Marcelo da
- Silva Ramon Lima
- Silva Shirley Seixas Pereira
- Silva Sofia Marques
- Sobral-Souza Thadeu
- Spironello Wilson Roberto
- Sponchiado Jonas
- Srbek-Araujo Ana Carolina
- SĂĄnchez Amadeo
- SĂĄnchez-Lalinde Catalina
- Tavares Valéria da Cunha
- Teixeira Fernanda Zimmermann
- Tellaeche Cintia
- Thompson Jeffrey J.
- Thornton Daniel
- Tirelli FlĂĄvia Pereira
- Tonetti Vinicius Rodrigues
- Tortato Fernando Rodrigo
- Tortato Marcos Adriano
- Towns Valeria
- Trevelin Leonardo Carreira
- Trigo Tatiane Campos
- Trinca Cristiano Trapé
- Ubaid FlĂĄvio Kulaif
- Vanderhoeven Ezequiel Andres
- Varela Diego M.
- Varzinczak Luiz Henrique
- Vasconcellos Daniela Rodrigues
- Velilla Marianela
- Versiani Natalia Fraguas
- Vieira Emerson M.
- Vieira Marcus VinĂcius
- Villar Nacho
- Vogliotti Alexandre
- Wallace Robert
- Widmer Cynthia Elisa
- Xavier Mariana Sampaio
- Yamane Marcelo Hideki
- Yanosky Alberto A.
- Yogui DĂ©bora Regina
- Zanin Marina
- Zanoni Juliani Bruna
- Zimbres Barbara
- Zocche Jairo José
- Publication venue
- 'Wiley'
- Publication date
- 01/07/2019
- Field of study
Xenarthransâanteaters, sloths, and armadillosâhave essential functions for ecosystem maintenance, such as insect control and nutrient cycling, playing key roles as ecosystem engineers. Because of habitat loss and fragmentation, hunting pressure, and conflicts with domestic dogs, these species have been threatened locally, regionally, or even across their full distribution ranges. The Neotropics harbor 21 species of armadillos, 10 anteaters, and 6 sloths. Our data set includes the families Chlamyphoridae (13), Dasypodidae (7), Myrmecophagidae (3), Bradypodidae (4), and Megalonychidae (2). We have no occurrence data on Dasypus pilosus (Dasypodidae). Regarding Cyclopedidae, until recently, only one species was recognized, but new genetic studies have revealed that the group is represented by seven species. In this data paper, we compiled a total of 42,528 records of 31 species, represented by occurrence and quantitative data, totaling 24,847 unique georeferenced records. The geographic range is from the southern United States, Mexico, and Caribbean countries at the northern portion of the Neotropics, to the austral distribution in Argentina, Paraguay, Chile, and Uruguay. Regarding anteaters, Myrmecophaga tridactyla has the most records (n = 5,941), and Cyclopes sp. have the fewest (n = 240). The armadillo species with the most data is Dasypus novemcinctus (n = 11,588), and the fewest data are recorded for Calyptophractus retusus (n = 33). With regard to sloth species, Bradypus variegatus has the most records (n = 962), and Bradypus pygmaeus has the fewest (n = 12). Our main objective with Neotropical Xenarthrans is to make occurrence and quantitative data available to facilitate more ecological research, particularly if we integrate the xenarthran data with other data sets of Neotropical Series that will become available very soon (i.e., Neotropical Carnivores, Neotropical Invasive Mammals, and Neotropical Hunters and Dogs). Therefore, studies on trophic cascades, hunting pressure, habitat loss, fragmentation effects, species invasion, and climate change effects will be possible with the Neotropical Xenarthrans data set. Please cite this data paper when using its data in publications. We also request that researchers and teachers inform us of how they are using these data
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- AbellĂł David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- Alemdag Gökçe nur
- Alexander Philip
- Alfarra Nada
- Alfitory Asma
- Alhabil Belal
- Alhaj Ahmad
- Alherz Mohammad
- Alhimyar Maryam
- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
- Ali Asmaa
- Ali Mahmoud
- Ali Shabina
- Alimi Marjan
- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
- Aljaber Dana
- Aljaberi Loay
- Aljanfi Asma
- Aljiffry Murad
- Aljohmani Lylas
- Alkhaledi Ahmad
- Alkhatib Ala'a Aldeen
- Alkhatib Haya
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- Allen Ingabire J.C.
- Almasri Murad
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- AlTaweel Mohammed
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- Dominguez Joaquina
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- Eldoseuky mohammed Amany
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- Espinosa-Bravo Martin
- Esposito Giovanni
- Essam Ibrahim El Desouki Muhammad Ahmed Muhammad
- Essam Eman
- Estalagem InĂȘs
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- Eswaye Haitem
- Etchill Eric
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- Eusebio Zegarra Ivan Edward
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- Fadel Ahmed
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- Fahmawee Toqa
- Fairfield Cameron J
- Falato Armando
- Falco Giuseppe
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- Fernandez-Diaz Maria Jose
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- FernĂĄndez MartĂnez Daniel
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- Finlay Ben
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- Fortuna Martins SĂłnia
- Foschi Diego
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- Fragoso Marta
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- GarcĂa FlĂłrez Luis JoaquĂn
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- Ghonaim Mennatullah
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- GonzĂĄlez GonzĂĄlez LucĂa
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- Hall Timothy
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- Ilieva Ivelina
- Iliopoulos Evangelos
- Ilker Ayse
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- Impellizzeri Harmony
- Inama Marco
- Infante Pino Hugo
- Ingabire J.C. Allen
- Innocent Aryon
- Ioannidis Argyrios
- Ioannidis Orestis
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- Ye Geoffrey
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- Zabiyaka Mikhail
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- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ăngelo Miguel
- ĂlgĂ„ Andreas
- Ăolak Elif
- Ămarik Toomas
- Ć atkauskas Mindaugas
- Ć kimelyte Monika
- Ć lenfuktas Vygintas
- Ć uman Oliver
- ĆœateckĂœ Jan
- Ćœumbakys Ćœygimantas
- Ćœupan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 30/01/2021
- Field of study
© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70â8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39â8·80) and upper-middle-income countries (2·06, 1·11â3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26â11·59) and upper-middle-income countries (3·89, 2·08â7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- AbellĂł David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- AlemdaÄ Gökçe nur
- Alexander Philip
- Alfarra Nada
- Alfitory Asma
- Alhabil Belal
- Alhaj Ahmad
- Alherz Mohammad
- Alhimyar Maryam
- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
- Ali Asmaa
- Ali Mahmoud
- Ali Shabina
- Alimi Marjan
- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
- Aljaber Dana
- Aljaberi Loay
- Aljanfi Asma
- Aljiffry Murad
- Aljohmani Lylas
- Alkhaledi Ahmad
- Alkhatib Ala'a Aldeen
- Alkhatib Haya
- Alkhatib Mo'min
- Allen Ingabire J.C.
- Almasri Murad
- Almeida Braga Sara
- Almeida Filipe
- Almigheerbi Alabas
- Almoqayyad Abdelrahman
- Almuzghi Fakhruddin
- Alnoury Mostafa
- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
- Alsalameh Barah
- Alsallaq Osama
- Alser Osaid
- Alshaar Muhammad
- Alsharef Tagwa
- Alsharqawi Nourah
- Alswerki Mohammad
- Altaf Amna
- Altaf Rabiya
- AlTaweel Mohammed
- Althini Abdulmunem Ahmed Mustafa
- Altibi Ahmed M.
- Altinel Yuksel
- Altiner Saygin
- Altomare Donato Francesco
- Altumei Zohoor
- Alvarez Rivera Alvaro Eduardo
- Alvarez-Cano Alethia
- Alves do Canto Brum Homero
- Alves Daniela Macedo
- Alves Magda
- Alvi Abdul
- Alwaheidi Malak
- Alwali Abdallah
- Alwerfally AbdulMawlay
- Alwhaidi Noor
- Alyafi Amr
- Alzabti Fatima
- Alzahaf Ahmed
- AlZohour Mohammad
- Amadou Magagi Ibrahim
- Amandito Radhian
- Amarin Justin Z.
- Amaro Margarida
- Ambrazevicius Marijus
- Amendola Alfonso
- Amin Leila
- Amine Souadka
- Amjad Talal
- Amorim Edgar
- Amro Adham
- Anandan Premkumar
- Anas khalifa Rawda
- Anastasio Lorenzo
- Andersson Yvette
- Andreotti Dario
- Andrew David
- André Benoßt
- Ang Sue Ean
- Angel Miguel
- Anggita Gultom Phebe
- Annapureddy Naga
- Anokhin Evgeny
- Ansaloni Luca
- Ansarei Dhirar
- Ansari Abdul Basit
- Antaky Marco
- Anthony Natasha
- Anthoulakis Christos
- Antonopoulou Maria Ioanna
- Anwar Mohamed
- Anwer Abdul Wahid
- Anyanwu Chikamuche
- Anyanwu Lofty-John
- Anyanwu Mercy Chinemerem
- Anyomih Theophilus Teddy Kojo
- Appukuttan Akhila
- Aquilino Fabrizio
- Archibald Jess
- ArciĂ©nega Yañez MarĂa del pilar
- Argentou Maria-Ioanna
- Argudo Nuria
- Argyriou Eleftherios Orestis
- Arias Madrid Natalia
- Aribi Sarra
- Arifin Ghafur Rasyid
- Arizpe Daniel
- Arnaud Alexis P
- Arora Bharti
- Arora Deeksha
- Arowolo Olukayode
- Arrangoiz Rodrigo
- Arslan Ekin
- Artigau Eva
- Ashfaq Ahsan
- Ashour Dina
- Ashour Firas
- Ashoushan Hana
- Ashraf Ahmed
- Ashraf Alaa
- Asif Ashar
- Asnel Dorisme
- Asok Anjitha
- Assa Rawan
- Assalhi Mohamed
- Asta Martina
- Asti Emanuele Luigi Giuseppe
- Atakul Onur
- Atallah Khalid
- Atanasov Boyko
- Atawneh Mohammad
- Athamneh Sarah
- Ather Muaaz
- Athisayaraj Thomas
- Atkociunas Aivaras
- Attia Mohamed
- Au Angela
- Awad Israa
- Awadallah Haneen
- Awaji Kholoud
- Awesat Eman
- Awolowo Ajibola
- Ayandipo Omobolaji
- Ayash Mohammad
- Ayau Fernanda
- Ayesh Kholoud
- Ayman El-sawy Esraa
- Ayoub Rami
- Aytac Erman
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- Garden O James
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- Gnintedeme Olivier Tchianze
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- Hall Timothy
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- Wondoh Paul M.
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- Wong Hsu Ven
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- Wong Jeremy
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- Wong Michael Pak-Kai
- Wong Sui-Weng
- Wong Tsz Lun Ernest
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- Woon-Shoo-Tong Xiao-Ming Sarah
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- Xanthopoulou Georgia
- Yabut Kenneth
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- Yaghi Nadine
- Yaghi Yasmine
- Yahia Mohamed Ali Mohamed
- Yakushkina Al'ona
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- Yang P Zichu
- YanikoÄlu Erkan
- Yanni Fady
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- Ye Geoffrey
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- You Lucia
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- YĂŒksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ăngelo Miguel
- ĂlgĂ„ Andreas
- Ăolak Elif
- Ămarik Toomas
- ÄepulienĂ© Daiva
- Ćahin Can
- Ć atkauskas Mindaugas
- Ć kimelytĂš Monika
- Ć lenfuktas Vygintas
- Ć uman Oliver
- ĆœateckĂœ Jan
- Ćœumbakys Ćœygimantas
- Ćœupan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/2022
- Field of study
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 studyâa multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58â5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23â0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
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- Publication venue
- 'Wiley'
- Publication date
- 01/01/2022
- Field of study
AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4âweeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4âweeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, PÂ =Â 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, PâConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
- Author
- Aawsaj Y.
- Abad-Gurumeta A.
- Abad-Motos A.
- Abadia M.
- Abassy J.
- Abate E.
- Abbasov A.
- Abbott D.
- Abbott T. E. F.
- Abdalla M.
- Abdeldayem H.
- Abdelkabir M.
- Abdelkader Salama I.
- Abdelkarim M.
- Abdelsamed A.
- Abdulfattah F.
- Abdulwahed E.
- Abdur-Rahman L. O.
- Abel M. K.
- Abelevich A.
- Abiyere H.
- Aboelkassem Ibrahim A.
- Aboharp Hasan Z.
- Abou Chaar M. K.
- Abreu da Silva A.
- Abubakar A.
- Abukhalaf S.
- Abukhalaf S. A.
- Acebes Garcia F.
- Achalandabaso Boira M.
- Acher A.
- Acosta Merida M. A.
- Acrich E.
- Adam Essa Adam M. E.
- Adamina M.
- Adamina M.
- Adamina M.
- Ademuyiwa A.
- Ademuyiwa A. O.
- Aderombi A.
- Adeyeye A.
- Adeyeye A.
- Adi H.
- Adiamah A.
- Adisa A.
- Afzal M. F.
- Agapov M.
- Agarwal A.
- Aggarwal M.
- Aghayeva A.
- Agilinko J.
- Agnes A.
- Agostini C.
- Agrawal A.
- Agrawal N.
- Agresta F.
- Aguado Lopez H.
- Aguiar Junior S.
- Aguilar Gonzalez M.
- Ahmed A.
- Ahmed A.
- Ahmed K.
- Ahmed M. E.
- Ahmed Z.
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- Publication venue
- 'Wiley'
- Publication date
- 01/01/2022
- Field of study
The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery
Safety of hospital discharge before return of bowel function after elective colorectal surgery
- Author
- Aabling R.R.
- Aba M.
- Abad-Motos A.
- Abbasguliyev H.
- Abdelgalil R.
- Abdelhameed F.
- Abdulrahman N.
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- Publication venue
- 'Wiley'
- Publication date
- 01/04/2020
- Field of study
© 2020 BJS Society Ltd Published by John Wiley & Sons LtdBackground: Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function. Methods: A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the ClavienâDindo classification system. Results: A total of 3288 patients were included in the analysis, of whom 301 (9·2 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4â7) and 7 (6â8) days respectively (P < 0·001). There were no significant differences in rates of readmission between these groups (6·6 versus 8·0 per cent; P = 0·499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0·90, 95 per cent c.i. 0·55 to 1·46; P = 0·659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34·7 versus 39·5 per cent; major 3·3 versus 3·4 per cent; P = 0·110). Conclusion: Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients
Safety of hospital discharge before return of bowel function after elective colorectal surgery
- Author
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- ZÌebraÌk R
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Background Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function. Methods A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the Clavien-Dindo classification system. Results A total of 3288 patients were included in the analysis, of whom 301 (9 center dot 2 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4-7) and 7 (6-8) days respectively (P < 0 center dot 001). There were no significant differences in rates of readmission between these groups (6 center dot 6 versus 8 center dot 0 per cent; P = 0 center dot 499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0 center dot 90, 95 per cent c.i. 0 center dot 55 to 1 center dot 46; P = 0 center dot 659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34 center dot 7 versus 39 center dot 5 per cent; major 3 center dot 3 versus 3 center dot 4 per cent; P = 0 center dot 110). Conclusion Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients
Safety of hospital discharge before return of bowel function after elective colorectal surgery
- Author
- A A Francis
- A A Francis
- A Abad-Motos
- A Abelevich
- A Adel
- A Agarwal
- A Aggiusti
- A Ahmed
- A Ahmeidat
- A Ajmera
- A Akisheva
- A Al-Azzawi
- A Al-Hadithi
- A Al-Salihi
- A Alagoa JoĂŁo
- A Alagoa JoĂŁo
- A Alberca-Paramo
- A Aldarragi
- A Ali
- A Ali
- A Alonso-Poza
- A Alsaif
- A Alshakhs
- A Amado
- A Amico
- A Armellini
- A Arnold
- A Arroyo
- A Asif
- A Asif
- A Atiyah
- A Aversano
- A B Aksoy
- A B Teasdale
- A Badran
- A Badran
- A Barberis
- A Bareh
- A Barina
- A Barkovskaya
- A Barrett
- A Bartnick
- A Bartoli
- A Basak
- A Batista
- A Batterham
- A Begaj
- A Belli
- A Belli
- A Benevento
- A Bettella
- A Bhargava
- A Biancafarina
- A Biancafarina
- A Birindelli
- A Birindelli
- A Bondurri
- A Borakati
- A Borakati
- A Bordanova Reverter
- A Borisova
- A Borisova
- A Boulbadaoui
- A Brescia
- A Brodie
- A Bugmann
- A Burzic
- A Busuttil
- A C Aru
- A C Bilgili
- A C Pedersen
- A C Quintela
- A Caiazzo
- A Campbell
- A Campbell
- A Campbell
- A Capozzolo
- A Casaril
- A Castro
- A Centeno
- A Chan
- A Charalabopoulos
- A Charalambous
- A Chiang
- A Chrimes
- A Chuang
- A Clavé Llavall
- A Clucas
- A Coomes
- A Couldrey
- A Craus-Miguel
- A Cruccu
- A Cruz
- A Cuenca RamĂrez
- A Cutler
- A D Ablett
- A D Ablett
- A D Antona
- A D Cevlik
- A Dawson
- A Dawson
- A De La Llave Serralvo
- A de Manzoni Garberini
- A de Manzoni Garberini
- A de Ruiter
- A Debiasio
- A Dharni
- A Di Cintio
- A Dias Matos
- A Drane
- A Dulskas
- A Dworkin
- A DĂaz Padillo
- A E Isik
- A Elbayouk
- A Emin
- A EspĂ MacĂas
- A F Rocha
- A Fares Bucci
- A Faustino
- A Fernandez
- A Fontani
- A Forero-Torres
- A Forero-Torres
- A Forero-Torres
- A Foulkes
- A Franceschi
- A Franceschi
- A Fung
- A G Marrosu
- A G Silva
- A Gabarski
- A Gadhvi
- A Galgano
- A Garcea
- A Garcia
- A GarcĂa-Vico
- A Gavrilina
- A Gemini
- A Gennai
- A Gharooni
- A Ghosh
- A Giani
- A Giannella
- A Gibbins
- A Gil
- A Gil-CatalĂĄn
- A Gilliam
- A Giri
- A Goede
- A Gopaul
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- A Gori
- A GrĂŒter
- A Guerreiro
- A Guglielmi
- A Guner
- A GĂłmez Del Pulgar
- A GĂŒldag
- A H Adam
- A H Dyer
- A Haji
- A Henkens
- A Herd
- A Heybourne
- A Hickman
- A Hogan
- A Hogan
- A Hotchkies
- A Huot
- A Hylands
- A I Pinillos
- A Ibrahim
- A Ioannidis
- A Ioannidis
- A Ipor
- A Isabello
- A Isik
- A Izquierdo Moreno
- A Izzarina
- A Jackson
- A Jacobson
- A Jain
- A James
- A Jones
- A Joseph
- A Jovaisaite
- A K Aly
- A Kanitkar
- A Karabulut
- A Kechagias
- A Kechagias
- A Kechagias
- A Kefleyesus
- A Kelliher
- A Khan
- A Khanan Kaabneh
- A Kilinç
- A Kisiel
- A Kisiel
- A Kler
- A Kopp
- A Kumar
- A Kurt
- A Kushairi
- A L Mihaljevic
- A Landaluce Olavarria
- A Laranjeira
- A Larcinese
- A Lauretta
- A Lauretta
- A Litvin
- A Litvin
- A Lo Conte
- A Loizidou
- A Longheu
- A Longshaw
- A Lorettu
- A Lucchi
- A Lucchi
- A M Brandsma
- A M Cinza
- A M Correia
- A M Estévez Diz
- A M Pektas
- A M Seckler
- A M Wiemann
- A Machado
- A Madhavan
- A Maffioli
- A Magri Piccinini
- A Mahmoud
- A Mandal
- A Manso
- A Marano
- A Marcos Rodrigo
- A Margarida
- A Mark-Christensen
- A Mark-Christensen
- A Maroli
- A Martensen
- A Martinez
- A Mathioulaki
- A McTighe
- A Mereu
- A Midgen
- A Millward
- A Mitra
- A Mondal
- A Mondal
- A Moosa
- A Mora
- A Morris
- A Mukkavilli
- A Nair
- A NavĂo
- A Nayeem
- A Neilson
- A Newton
- A Nicolaides
- A Nirmalanantha
- A Nur
- A O Sunay
- A O'Neill
- A OjakÀÀr
- A Ong
- A Otto
- A Otto
- A Ozolins
- A P Torre
- A Pacheco
- A PaclĂk
- A Palkhi
- A Palmer
- A Pandya
- A Panyko
- A Paolucci
- A Papanikolaou
- A Parisi
- A Paspala
- A Percassi
- A Percivale
- A Pergel
- A Pesce
- A Picciariello
- A Picciariello
- A Pietrabissa
- A Pimentel
- A Piperidis
- A Poncelet
- A Portugal MartĂnez
- A Powell-Chandler
- A Powell-Chandler
- A Prodromidou
- A Pullybank
- A PĂ©rez Ortega
- A Quevedo
- A R Loureiro
- A R Martins
- A R Pentony
- A Ragavoodoo
- A Ragavoodoo
- A Rahman
- A Rais
- A Ramdin
- A Ramjeeawon
- A Ramwell
- A Rankin
- A Rashid
- A Realis Luc
- A Reddy
- A Refalo
- A Rencuzogullari
- A Ribeiro
- A RodrĂguez SĂĄnchez
- A Roggiani
- A Roman-Rando
- A Ruggieri
- A Ruparelia
- A Ruzzenente
- A Rylance
- A S Ferreira
- A S Hussain
- A Saba
- A Sagnotta
- A Sagnotta
- A Sagredo Cuartango
- A Saha
- A Saiyed
- A Saiyed
- A Samee
- A Sangheli
- A Savchenko
- A Saxena
- A Schimera
- A Schizas
- A Scott
- A Semiz
- A SgrĂČ
- A SgrĂČ
- A SgrĂČ
- A SgrĂČ
- A Shashidhara
- A Silva
- A Silva
- A Simioni
- A Simioni
- A Simioni
- A Singh
- A SivinĆĄ
- A SkalickĂœ
- A Skavysh
- A Skull
- A Slepavicius
- A Soares
- A Soares
- A Soma
- A Southgate
- A Sparke
- A Spaziani
- A Spinelli
- A Sunal
- A SĂĄnchez LĂłpez
- A Tamosiunas
- A Tang
- A Tınaz
- A Torrance
- A Trap
- A Trujillo Barbadillo
- A TruĆĄkovs
- A Tura
- A Turunen
- A Ucar
- A Unsworth
- A Uyanik
- A V Robinson
- A Vadillo-Bohorquez
- A van der Pool
- A Vanoni
- A Varghese
- A Vedadi
- A Venara
- A Vignali
- A Vucicevic
- A W Azhar
- A Walsh
- A Warsame
- A Wells
- A Wilkes
- A Yagız Sen
- A Yagız Sen
- A Yagız Sen
- A Yalcinkaya
- A Yanishev
- A Yanishev
- A Yanishev
- A Yebes
- A Yebes
- A Yoong
- A Yuksek
- A Z Sahin
- A Zaidi
- A Zoikas
- A Zoikas
- Aab Wyche
- Aaw van Geloven
- Ahw van de Ven
- Ashm van Dalen
- Ashm van Dalen
- Asi Hassane
- B A Perrone
- B Akram
- B Aksoy
- B Aksoy
- B Allen
- B B Ozkan
- B B Ozmen
- B Baljer
- B Baykan
- B Berry
- B Blaser
- B Blaser
- B Boev
- B Borghi
- B Braccio
- B Buckland
- B Campbell
- B Campillo Alonso
- B Can
- B Carhart
- B Castro
- B Chandrasekar
- B Chrisp
- B Cirillo
- B Cismasiu
- B Cresswell
- B D Brandao
- B Demirtas
- B Desmond
- B Dias
- B Dieguez
- B Djeugam
- B E Baki
- B E Baki
- B Ekci
- B Emiroglu
- B Fakim
- B Fanibi
- B Frezza
- B Gagliardi
- B Gagliardi
- B Gurung
- B GĂŒner
- B Hardy
- B Ibrahim
- B J Finch
- B J Finch
- B Jenkins
- B Karip
- B Kelly
- B KoloĆĄovĂĄ
- B Kulendrarajah
- B Kutlu
- B L van Leeuwen
- B Langenhoff
- B Liu
- B M Elliott
- B M Elliott
- B Mekaeil
- B Mikhail
- B Mollavelioglu
- B Molteni
- B Molteni
- B Mutlu
- B N Jepsen
- B N Vieira
- B N Vieira
- B Nasimi
- B Ng
- B Pando
- B Ribeiro da Silva
- B Ricardo Felipe
- B S Rocha
- B S Yilmaz
- B Shirazi
- B Shishkin
- B Singh
- B Smith
- B Soares
- B Stainer
- B Stanfield
- B Stubbs
- B Söyleyici
- B Thompson
- B Walters
- B Woodburn
- B Yeap
- B YĂŒksek
- B YĂŒksek
- Bpl Wijnhoven
- C Adiyaman
- C Aktuna
- C Akyol
- C Alves-Vale
- C Amey
- C Atar
- C Auty
- C B Recuenco
- C Barkolias
- C Belluco
- C Bianchi
- C Bianco
- C Bilen
- C Blasco Andrés
- C Botelho
- C Bowers
- C Bowman
- C Brigand
- C Burford
- C Bustamante Recuenco
- C C Lopes Moreira
- C C Lopes Moreira
- C Cabaleiro Barciela
- C Cachia
- C Campanaro
- C Campbell
- C Carden
- C Carey
- C Carneiro
- C Caula Freixa
- C Cefai
- C CerdĂĄn
- C Cerra
- C Ceylan
- C Chipeta
- C Chong
- C Ciubotaru
- C Ciurleo
- C Codony Bassols
- C Conti
- C Corino
- C Costa
- C Costa
- C Coulter
- C Cunha
- C Curtis
- C D Brumfitt
- C D Brumfitt
- C D Roche
- C D SkejĂž
- C De Nisco
- C De Nisco
- C De Padua
- C Del Basso
- C Doherty
- C Donaldson
- C Donnelly
- C Dunmore
- C Dörr-Harim
- C Ede
- C English
- C Evans
- C F Campo Betancourth
- C Fairén Oro
- C Fairén Oro
- C Faqihinejad
- C Feleppa
- C Ferrari
- C Ferrari
- C Fidalgo Antunes
- C Fioriti
- C Foppa
- C Galata
- C Gallagher
- C Genzano
- C Gilsanz
- C Green
- C H Knowles
- C Haglund
- C Haran
- C Harmston
- C Hensher
- C Hew
- C Hobson
- C Hoff
- C Horner
- C I Ciubotaru
- C I Wells
- C J Fairfield
- C Jain
- C James
- C Jimenez Viñas
- C Jiménez Relimpio
- C K Kang
- C Kerem
- C Kind
- C Kontovounisios
- C Koutserimpas
- C Kruger
- C L Boon
- C L Piong
- C Leavey
- C Lye
- C M Borg
- C M Cheong
- C M Ruddy
- C Macleod Hall
- C Maden
- C Marcano Chavez
- C Mason
- C Massaiu
- C Matthews
- C Maxwell-Armstrong
- C Mazzeo
- C McCaughey
- C McClarty
- C McCusker
- C Mercer
- C Moehwald
- C Montalvo Olmedo
- C Monteiro
- C Monteiro
- C Mosquera Fernandez
- C Mulvenna
- C Muniesa
- C Murphy
- C Nascimento
- C Nayak
- C Nevado
- C Neves-Marques
- C Neves-Marques
- C Ngai
- C Olmedo Moreno
- C Olmedo Moreno
- C Ortega
- C Osborne
- C P Madsen
- C Pace
- C Pala
- C Palmer
- C Palmer
- C Pastor Idoate
- C Pedrazzani
- C Pineño-Flores
- C R McDuling
- C Ralston
- C Redclift
- C Rettaroli
- C Ricolleau
- C Ross
- C Roxburgh
- C Russell
- C Russell
- C S Jones
- C Sahin
- C Salaris
- C SamartĂn Toimil
- C Sellahewa
- C Skipworth
- C Soare
- C Soldevila-Verdeguer
- C Sparta
- C Spirito
- C Stevenson
- C Thakrar
- C Thakrar
- C Thompson
- C Thorn
- C Toh
- C Toh
- C Trueba-Collado
- C Turner
- C Uribe Galeano
- C V Nielsen
- C V PĂ©rez Guarinos
- C Van Rhee
- C Velez
- C Warner
- C Warner
- C Wickstone
- C Wilson
- C Wong
- C Wong
- C Y BoztuÄ
- C Y Hey
- C Y Hey
- C Yelkenci
- Cam Aarts
- Cjl Molenaar
- D A Chapman
- D A Ferrusola Diaz
- D A McNamara
- D A Thomas
- D AbellĂł
- D Albayrak
- D Alsoof
- D Alves
- D Ambrona-Zafra
- D Aveiro
- D B O'Connor
- D Balalis
- D Balalis
- D Bandyopadhyay
- D Benvenuto
- D Bodrov
- D Boersma
- D Bowley
- D Bruce
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- D Cavadas
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- D Clerc
- D Clerc
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- D Coletta
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- D Conti
- D Correia
- D Costa Santos
- D Cuicchi
- D D van den Bos
- D Dahya
- D Danys
- D de Roy van Zuidewijn
- D Defriend
- D Degaetano
- D Deksnis
- D Dimitrov
- D E Lee
- D Elliott
- D F Altomare
- D Foschi
- D GalvĂŁo
- D GarcĂa Olmo
- D Gereklioglu
- D Gobatti
- D Gutmann
- D H Kim
- D Hahnloser
- D Horne
- D J AparĂcio
- D J AparĂcio
- D J Drury
- D Jimulia
- D Jones
- D JuliĂ Bergkvist
- D K Manatakis
- D K Manatakis
- D Korkolis
- D Kus
- D Lewis
- D Limnatitou
- D M Baker
- D M JordĂŁo
- D M Mendis
- D M Rojoa
- D M Voeten
- D Magagnano
- D Maioli
- D Mala
- D Mason
- D Mason
- D Mason
- D Melo
- D Mendez
- D Mijalkov
- D Montwedi
- D Morris
- D Mutlu
- D N Veiga
- D Nakakande
- D Negre Parra
- D Negre Parra
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- D Nguen
- D O'Gorman
- D O'Neill
- D Ongaro
- D Panagiotou
- D Papaconstantinou
- D Parini
- D Parini
- D Parker
- D Petermann
- D R Shah
- D Ratnasingham
- D Rega
- D Reveendran
- D Rojoa
- D S Rye
- D Sabia
- D Sapre
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- D Sasia
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- D Vernon
- D Waldron
- D Wang
- D Welman
- D West
- D Yilmaz
- D Yilmaz
- D Ăzen
- Dot Alawode
- Dwe Lim
- E 't Hart
- E Aitken
- E Alberch CamprubĂ
- E Alizade
- E Alonso Batanero
- E Altintas
- E Alvarez
- E Amorim
- E Amorim
- E Andolfi
- E Appleby
- E Arslan
- E Arslan
- E Artioli
- E B Gul
- E Baena Sanfeliu
- E Baggus
- E Barbosa
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- E Bertilone
- E Bevilacqua
- E Bonati
- E Boyle
- E Bradley
- E Brazier
- E Brazitikou
- E Brinkhuis
- E Buchanan
- E C Ä°Ćlek
- E Cahya
- E Camarero
- E Campbell
- E Cesmeli
- E Ciccioli
- E Colangelo
- E Crisp
- E Cucinotta
- E Cuello
- E D Padilla Zegarra
- E De Luca
- E Del Pozo Andrés
- E Diego Alonso
- E Disçi
- E Downs
- E Duchalais
- E Duchalais
- E Duchalais
- E Duchalais
- E Dumange
- E Epanomeritakis
- E Erdas
- E Erdas
- E Eren
- E Espin-Basany
- E Espin-Basany
- E Etel
- E Evans
- E Falsetti
- E Ferrini
- E Finotti
- E Fytrou
- E G Boerma
- E G Turk
- E Gablenz
- E Goldin
- E H Ong
- E Holden
- E Hu
- E Irwin
- E J Flint
- E J Hazebroek
- E Jeffrey
- E K Sel
- E Karagöz
- E Khogali
- E Kilgallon
- E Köseoglu
- E Lazzarini
- E Lewis
- E Li
- E Ling
- E Lutovinova
- E Lyulenina
- E M Hoeks
- E M van Praag
- E Mackenzie
- E Mackenzie
- E Malcevs
- E Marra
- E MarĂnez-Hurtado
- E Masiha
- E Massie
- E Matthee
- E Mills
- E Miranda
- E Mitkov
- E Moggia
- E Morrissey
- E Mulhare
- E N Cinar
- E N Cinar
- E Nawaz
- E Ntakomyti
- E O Howard
- E O'Connell
- E Ogundiya
- E Onur
- E Pentti
- E Picone
- E PoĆĄkus
- E Puig Lao
- E Riordan
- E Romanova
- E Romero Pujana
- E S Kristensen
- E Schembari
- E Segalini
- E Segalini
- E Seite
- E Senyigit
- E Sewart
- E Smith
- E Spartalis
- E Stark
- E SĂĄnchez
- E Thompson
- E Tiftik
- E Tiftik
- E Tunc
- E Vendramin
- E Virgilio
- E Westerduin
- E Williamson
- E Wright
- E Yanikoglu
- E Yarenci
- E Zeb
- Emf van de Voort
- Etj Richardson
- F A Akın
- F A Chaudhry
- F A Mura
- F A Ramos Jiménez
- F A Uygur
- F Abdelhameed
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- F Dalzell
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- F Ehlern
- F EirĂł
- F EirĂł
- F F Di Mola
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- F Feroci
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- F Ferrara
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- F Kutluk
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- F Muneeb
- F O'Brien
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- F Ozoglu
- F P Kristensen
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- F Vivian
- F W Gan
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- F Wood
- F Y Liu
- F Y Liu
- F Zeynalov
- G A Loche
- G A Mura
- G A PellicanĂČ
- G Aitken
- G Alemdag
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- G Poillucci
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- V Adamo
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- X Sousa
- Y Ali
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- Y Bhahirathan
- Y Bhahirathan
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- Y Chechelnitskaya
- Y D Lee
- Y Demiroglu
- Y E Alim
- Y E Aytin
- Y E Karapinar
- Y El Kasmy El Kasmi
- Y El Kasmy El Kasmi
- Y El Kasmy El Kasmi
- Y Embury-Young
- Y Gercek
- Y J Alame
- Y J Lee
- Y J Soh
- Y K Goh
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- Y Karaman
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- Y Kaya
- Y L Pang
- Y L Wang
- Y Li
- Y M Tissen
- Y Mahmoudi
- Y Majeed
- Y Mitkov
- Y N Goh
- Y Nikookam
- Y Q Yeo
- Y Qamar
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- Y Toyi
- Y Vroom
- Y Xiao
- Y Youssef
- Y Z Beh
- Yiz Acherman
- Z Abdulrahman
- Z Akbar
- Z Al-Saraff
- Z Al-Sarraf
- Z Ali
- Z B Koçak
- Z Ballarini
- Z Carrington
- Z Garoufalia
- Z Goolam-Mahomed
- Z H Sam
- Z Habib
- Z Iqbal
- Z Millar
- Z Ngwenya
- Z Noriega
- Z S Demirci
- Z Sheikh
- Z Xuan Tan
- Z Y Boh
- Z Yi Tew
- Z Yi Tew
- Z Yusuf
- Ă Navarro Barrios
- Ăagri Girit
- Ă Dockry
- Ă KĂŒrklĂŒ
- Ă Uslu
- Ă Uslu
- Ă Yumurtaci
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2020
- Field of study
Background: Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function.Methods: A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the Clavien-Dindo classification system.Results: A total of 3288 patients were included in the analysis, of whom 301 (9.2 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4-7) and 7 (6-8) days respectively (P < 0.001). There were no significant differences in rates of readmission between these groups (6.6 versus 8.0 per cent; P = 0.499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0.90, 95 per cent c.i. 0.55 to 1.46; P = 0.659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34.7 versus 39.5 per cent; major 3.3 versus 3.4 per cent; P = 0.110).Conclusion: Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients
Timing of nasogastric tube insertion and the risk of postoperative pneumonia: an international, prospective cohort study
- Author
- 't Hart E.
- Aabling R. R.
- Aarts C. A. M.
- Aba M.
- Abad-Motos A.
- Abbasguliyev H.
- Abdelgalil R.
- Abdelhameed F.
- Abdulrahman N.
- Abdulrahman S. M. F.
- Abdulrahman Z.
- Abelevich A.
- AbellĂł D.
- Ablett A. D.
- Ablett A. D.
- Abrisqueta J.
- Acherman Y. I. Z.
- Adam A. H.
- Adamo V.
- Adams S. I. B.
- Adel A.
- Adeleye O.
- Adeusi L.
- Adiyaman C.
- Adra M.
- Afsar H. B.
- Aftab R.
- Agarwal A.
- Agarwal T.
- Agca M. H.
- Aggiusti A.
- Agresta F.
- Aguilar-MartĂnez M. M.
- Aguilera M. L.
- Aguilera M. L.
- Aguilera M. L.
- Ahmad H.
- Ahmed A.
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- Ahmed K.
- Ahmed M.
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- Ahmed S.
- Ahmed S.
- Ahmed W. U. R.
- Ahmeidat A.
- Ahsan S. D.
- Ainsworth P.
- Aitken E.
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- Akay F. E.
- Akbani U.
- Akbar Z.
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- Aldarragi A.
- Alemdag G.
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- ĆœebrĂĄk R.
- ĆœebrĂĄk R.
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2020
- Field of study
Aim: Aspiration is a common cause of pneumonia in patients with postoperative ileus. Insertion of a nasogastric tube (NGT) is often performed, but this can be distressing. The aim of this study was to determine whether the timing of NGT insertion after surgery (before versus after vomiting) was associated with reduced rates of pneumonia in patients undergoing elective colorectal surgery. Method: This was a preplanned secondary analysis of a multicentre, prospective cohort study. Patients undergoing elective colorectal surgery between January 2018 and April 2018 were eligible. Those receiving a NGT were divided into three groups, based on the timing of the insertion: routine NGT (inserted at the time of surgery), prophylactic NGT (inserted after surgery but before vomiting) and reactive NGT (inserted after surgery and after vomiting). The primary outcome was the development of pneumonia within 30Â days of surgery, which was compared between the prophylactic and reactive NGT groups using multivariable regression analysis. Results: A total of 4715 patients were included in the analysis and 1536 (32.6%) received a NGT. These were classified as routine in 926 (60.3%), reactive in 461 (30.0%) and prophylactic in 149 (9.7%). Two hundred patients (4.2%) developed pneumonia (no NGT 2.7%; routine NGT 5.2%; reactive NGT 10.6%; prophylactic NGT 11.4%). After adjustment for confounding factors, no significant difference in pneumonia rates was detected between the prophylactic and reactive NGT groups (odds ratio 1.03, 95% CI 0.56â1.87, PÂ =Â 0.932). Conclusion: In patients who required the insertion of a NGT after surgery, prophylactic insertion was not associated with fewer cases of pneumonia within 30Â days of surgery compared with reactive insertion