15,463 research outputs found
X-ray film holder permits single continuous picture of tubing joint
X ray technique produces a clear continuous picture of a welded brazed tubing joint on a single film with one exposure. A stationary X ray source located in the plane of the joint to be inspected, a means of rotating the tube, and a unique internal film holder and positioning fixture are used
The Most Detailed Picture Yet of an Embedded High-mass YSO
High-mass star formation is not well understood chiefly because examples are
deeply embedded, relatively distant, and crowded with sources of emission.
Using VLA and VLBA observations of water and SiO maser emission, we have mapped
in detail the structure and proper motion of material 20-500 AU from the
closest high-mass YSO, radio source-I in the Orion KL region. We observe
streams of material driven in a rotating, wide angle, bipolar wind from the
surface of an edge-on accretion disk. The example of source-I provides strong
evidence that high-mass star formation proceeds via accretionComment: typo corrected and word added to abstract 6 pages including 4 B&W
figures. To appear in the Proceeding of IAU Symposium 221, Star Formation at
High Angular Resolution, Editors M. Burton, R. Jayawardhana & T. Bourke,
Astronomical Society of the Pacifi
The opposites task: Using general rules to test cognitive flexibility in preschoolers
A brief narrative description of the journal article, document, or resource. Executive functions play an important role in cognitive development, and during the preschool years especially, children's performance is limited in tasks that demand flexibility in their behavior. We asked whether preschoolers would exhibit limitations when they are required to apply a general rule in the context of novel stimuli on every trial (the "opposites" task). Two types of inhibitory processing were measured: response interference (resistance to interference from a competing response) and proactive interference (resistance to interference from a previously relevant rule). Group data show 3-year-olds have difficulty inhibiting prepotent tendencies under these conditions, whereas 5-year-olds' accuracy is near ceiling in the task. (Contains 4 footnotes and 1 table.
Cryptic choice of conspecific sperm controlled by the impact of ovarian fluid on sperm swimming behavior
Despite evidence that variation in male–female reproductive compatibility exists in many fertilization systems, identifying mechanisms of cryptic female choice at the gamete level has been a challenge. Here, under risks of genetic incompatibility through hybridization, we show how salmon and trout eggs promote fertilization by conspecific sperm. Using in vitro fertilization experiments that replicate the gametic microenvironment, we find complete interfertility between both species. However, if either species’ ova were presented with equivalent numbers of both sperm types, conspecific sperm gained fertilization precedence. Surprisingly, the species’ identity of the eggs did not explain this cryptic female choice, which instead was primarily controlled by conspecific ovarian fluid, a semiviscous, protein-rich solution that bathes the eggs and is released at spawning. Video analyses revealed that ovarian fluid doubled sperm motile life span and straightened swimming trajectory, behaviors allowing chemoattraction up a concentration gradient. To confirm chemoattraction, cell migration tests through membranes containing pores that approximated to the egg micropyle showed that conspecific ovarian fluid attracted many more spermatozoa through the membrane, compared with heterospecific fluid or water. These combined findings together identify how cryptic female choice can evolve at the gamete level and promote reproductive isolation, mediated by a specific chemoattractive influence of ovarian fluid on sperm swimming behavior
The population of SNe/SNRs in the starburst galaxy Arp 220. A self-consistent analysis of 20 years of VLBI monitoring
The nearby ultra-luminous infrared galaxy (ULIRG) Arp 220 is an excellent
laboratory for studies of extreme astrophysical environments. For 20 years,
Very Long Baseline Interferometry (VLBI) has been used to monitor a population
of compact sources thought to be supernovae (SNe), supernova remnants (SNRs)
and possibly active galactic nuclei (AGNs). Using new and archival VLBI data
spanning 20 years, we obtain 23 high-resolution radio images of Arp 220 at
wavelengths from 18 cm to 2 cm. From model-fitting to the images we obtain
estimates of flux densities and sizes of all detected sources. We detect radio
continuum emission from 97 compact sources and present flux densities and sizes
for all analysed observation epochs. We find evidence for a LD-relation within
Arp 220, with larger sources being less luminous. We find a compact source LF
with , similar to SNRs in normal
galaxies. Based on simulations we argue that there are many relatively large
and weak sources below our detection threshold. The observations can be
explained by a mixed population of SNe and SNRs, where the former expand in a
dense circumstellar medium (CSM) and the latter interact with the surrounding
interstellar medium (ISM). Nine sources are likely luminous, type IIn SNe. This
number of luminous SNe correspond to few percent of the total number of SNe in
Arp 220 which is consistent with a total SN-rate of 4 yr as inferred
from the total radio emission given a normal stellar initial mass function
(IMF). Based on the fitted luminosity function, we argue that emission from all
compact sources, also below our detection threshold, make up at most 20\% of
the total radio emission at GHz frequencies.Comment: Accepted for publication in Astronomy and Astrophysic
Mathematical Model of Easter Island Society Collapse
In this paper we consider a mathematical model for the evolution and collapse
of the Easter Island society, starting from the fifth century until the last
period of the society collapse (fifteen century). Based on historical reports,
the available primary sources consisted almost exclusively on the trees. We
describe the inhabitants and the resources as an isolated system and both
considered as dynamic variables. A mathematical analysis about why the
structure of the Easter Island community collapse is performed. In particular,
we analyze the critical values of the fundamental parameters driving the
interaction humans-environment and consequently leading to the collapse. The
technological parameter, quantifying the exploitation of the resources, is
calculated and applied to the case of other extinguished civilization (Cop\'an
Maya) confirming, with a sufficiently precise estimation, the consistency of
the adopted model.Comment: 9 pages, 1 figure, final version published on EuroPhysics Letter
Collateral and Debt Maturity Choice. A Signaling Model
This paper derives optimal loan policies under asymmetric information where banks offer loan contracts of long and short duration, backed or unbacked with collateral. The main novelty of the paper is that it analyzes a setting in which high quality firms use collateral as a complementary device along with debt maturity to signal their superiority. The least-cost signaling equilibrium depends on the relative costs of the signaling devices, the difference in firm quality and the proportion of good firms in the market. Model simulations suggest a non-monotonic relationship between firm quality and debt maturity, in which high quality firms have both long-term secured debt and short-term secured or non-secured debt.
A library of infectious hepatitis C viruses with engineered mutations in the E2 gene reveals growth-adaptive mutations that modulate interactions with scavenger receptor class B type I
While natural hepatitis C virus (HCV) infection results in highly diverse quasispecies of related viruses over time, mutations accumulate more slowly in tissue culture, in part because of the inefficiency of replication in cells. To create a highly diverse population of HCV particles in cell culture and identify novel growth-enhancing mutations, we engineered a library of infectious HCV with all codons represented at most positions in the ectodomain of the E2 gene. We identified many putative growth-adaptive mutations and selected nine highly represented E2 mutants for further study: Q412R, T416R, S449P, T563V, A579R, L619T, V626S, K632T, and L644I. We evaluated these mutants for changes in particle-to-infectious-unit ratio, sensitivity to neutralizing antibody or CD81 large extracellular loop (CD81-LEL) inhibition, entry factor usage, and buoyant density profiles. Q412R, T416R, S449P, T563V, and L619T were neutralized more efficiently by anti-E2 antibodies and T416R, T563V, and L619T by CD81-LEL. Remarkably, all nine variants showed reduced dependence on scavenger receptor class B type I (SR-BI) for infection. This shift from SR-BI usage did not correlate with a change in the buoyant density profiles of the variants, suggesting an altered E2-SR-BI interaction rather than changes in the virus-associated lipoprotein-E2 interaction. Our results demonstrate that residues influencing SR-BI usage are distributed across E2 and support the development of large-scale mutagenesis studies to identify viral variants with unique functional properties. IMPORTANCE Characterizing variant viruses can reveal new information about the life cycle of HCV and the roles played by different viral genes. However, it is difficult to recapitulate high levels of diversity in the laboratory because of limitations in the HCV culture system. To overcome this limitation, we engineered a library of mutations into the E2 gene in the context of an infectious clone of the virus. We used this library of viruses to identify nine mutations that enhance the growth rate of HCV. These growth-enhancing mutations reduced the dependence on a key entry receptor, SR-BI. By generating a highly diverse library of infectious HCV, we mapped regions of the E2 protein that influence a key virus-host interaction and provide proof of principle for the generation of large-scale mutant libraries for the study of pathogens with great sequence variability
Axial Symmetry and Rotation in the SiO Maser Shell of IK Tauri
We observed v=1, J=1-0 43-GHz SiO maser emission toward the Mira variable IK
Tauri (IK Tau) using the Very Long Baseline Array (VLBA). The images resulting
from these observations show that SiO masers form a highly elliptical ring of
emission approximately 58 x 32 mas with an axial ratio of 1.8:1. The major axis
of this elliptical distribution is oriented at position angle of ~59 deg. The
line-of-sight velocity structure of the SiO masers has an apparent axis of
symmetry consistent with the elongation axis of the maser distribution.
Relative to the assumed stellar velocity of 35 km/s, the blue- and red-shifted
masers were found to lie to the northwest and southeast of this symmetry axis
respectively. This velocity structure suggests a NW-SE rotation of the SiO
maser shell with an equatorial velocity, which we determine to be ~3.6 km/s.
Such a NW-SE rotation is in agreement with a circumstellar envelope geometry
invoked to explain previous water and OH maser observations. In this geometry,
water and OH masers are preferentially created in a region of enhanced density
along the NE-SW equator orthogonal to the rotation/polar axis suggested by the
SiO maser velocities.Comment: 17 Pages, 4 figures (2 color); accepted for publication in Ap
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