Rappresentazione dello spazio ed egocentrismo percettivo

This paper presents the results of a research on perspective taking, aimedto investigate two specific themes: the age when the child leaves perceptiveegocentrism, and gender differences in the management of spatial referencesystems. The innovative contribution of this work is that it has addressedthe issue with a not abused tool for this field: the videogame, whichhas been the data collecting instrument for the experimental research project.The paper addresses the issue of the representation of space in the child,from Piaget to neurosciences, describing the reference systems competingin the representation of space and the Piagetian conceptual framework, andreporting the scientific debate on the "three mountains task" and the spatialtheory of empathy.Once described the conceptual framework, the text presents the researchdesign, the path for design and development of the videogame, the methodsfor data collection and discusses the results obtained. The experimentalprocess has led to observe how the cognitive processes involved inspace representation are processes also involved in the management of inter-subjective relationship modes. The age range 6-7 years and 12-13 yearsis the period in which the child learns the change of point of view, in the literalsense, and, in a broad sense, realizes that the world can not be seenone way, that space can be manipulated, that it is possible to consider thethoughts and emotions of others. It is the age in which the capacity for empathydevelops, understood as the ability to see the world through the eyesof others.L’articolo presenta i risultati di una ricerca sulla rappresentazione dello spazioe sul perspective taking in età evolutiva, volta ad indagare due temi specifici:l’età in cui il bambino abbandona, di norma, l’egocentrismo percettivo,e le differenze di genere nella gestione dei sistemi di riferimento spaziale.Il lavoro affronta il tema con uno strumento non abusato per questocampo, un videogame, progettato e sviluppato ad hoc, che ha costituito lostrumento di raccolta dei dati per il progetto di ricerca sperimentale.Il lavoro inizialmente approfondisce il tema della rappresentazione dellospazio nel bambino, da Piaget alle neuroscienze, descrivendo i sistemi di riferimentoconcorrenti nella rappresentazione dello spazio, l’impianto concettualepiagetiano, riportando il dibattito scientifico sulle “tre montagne”e sulla teoria spaziale dell’empatia. Descritto il framework concettuale, il testoillustra il disegno di ricerca, il percorso di design e sviluppo del videogame,la modalità di raccolta dei dati e discute i risultati ottenuti. Il percorsosperimentale ha portato a constatare come i processi cognitivi coinvolti nelleattività peculiari di rappresentazione dello spazio siano processi coinvoltinella gestione delle modalità di relazione intersoggettiva. La fascia di etàcompresa tra 6-7 anni e 12-13 anni è il periodo in cui il bambino apprende ilcambiamento di punto di vista, in senso letterale e, in accezione ampia, realizzache il mondo non può essere visto a senso unico, che lo spazio si puòmanipolare, che è possibile prendere in considerazione i pensieri e le emozionialtrui. È l'età in cui si sviluppa la capacità di empatia, intesa come la capacitàdi rimanere se stessi mettendosi al posto degli altri posto di altri, pervedere il mondo con gli occhi altrui

The physical effort required from professional football players in different playing positions

The purpose of this study is to examine the physical effort required at professional football players (Italian Championship) in relation to the examination of a series of friendly matches at different times of the year, compared to their role, using the technology of GPS, for finalizing the training to improve the sport performance. The activities of players were monitored using GPS technology with a sampling rate of 10 Hz. The total distance covered, distances with different speed and accelerations were analyzed in relation to five different roles: (CD) central defenders, (FB) full-backs, (M) midfielders, (AM) advanced midfielders and (A) attackers. Players activities were monitored using GPS technology with a sampling rate of 10 Hz. Total distance covered, distance at different speeds and accelerations were analyzed in relation in five different roles: (CD) central defenders, (FB) full-backs, (M) midfielders, (AM) advanced midfielders and (A) attackers. The maximum covered distance (over 10 km) during a friendly match was reached by the third (FB), midfielders (M) and advanced midfielders (AM); The same ones have covered, too, the greatest distances in high-intensity running (> 16 km/h); instead, the attackers and central defenders covered the distance in high power. The full-backs (FB) and Advanced Midfielders (AM) have producted high acceleration and deceleration compared to other roles, while midfielders (M) have developed greater metabolic power. Finally, the end-of-season results were compared with the data gained at the beginning of the year and important differences between the various roles were noted

Motor imagery, perspective taking and gender differences: A VVIQ2-based study

Scientific literature highlighted gender differences in spatial orientation. In particular, men and women differ in terms of the navigational processes they use in daily life. Scientific literature highlighted that women use analytical strategies while men tend to use holistic strategies. Furthermore, studies exploring gender differences in self-reported dream perspectives reported that women dream mainly in first person and men mainly in third person. This work used Vividness of Movement Imagery Questionnaire-2 to verify if gender differences in perspective taking last also in motor imagery practice. The aim of VVIQ2 questionnaire is to determine the vividness of movement imagery. In the VVIQ2, the image can be obtained watching oneself while performing the movement from an external point of view (External Visual Imagery), or from an internal point of view, as if you were looking out through your own eyes while performing the movement (Internal Visual Imagery). The Questionnaire was administered to students of Sports Sciences Degree from University of Salern

Smoking cessation is associated with lower disease activity and predicts cardiovascular risk reduction in rheumatoid arthritis patients

Objectives: Smoking is a major risk factor for the development of both cardiovascular disease (CVD) and RA and may cause attenuated responses to anti-rheumatic treatments. Our aim was to compare disease activity, CVD risk factors and CVD event rates across smoking status in RA patients. Methods: Disease characteristics, CVD risk factors and relevant medications were recorded in RA patients without prior CVD from 10 countries (Norway, UK, Netherlands, USA, Sweden, Greece, South Africa, Spain, Canada and Mexico). Information on CVD events was collected. Adjusted analysis of variance, logistic regression and Cox models were applied to compare RA disease activity (DAS28), CVD risk factors and event rates across categories of smoking status. Results: Of the 3311 RA patients (1012 former, 887 current and 1412 never smokers), 235 experienced CVD events during a median follow-up of 3.5 years (interquartile range 2.5-6.1). At enrolment, current smokers were more likely to have moderate or high disease activity compared with former and never smokers (P < 0.001 for both). There was a gradient of worsening CVD risk factor profiles (lipoproteins and blood pressure) from never to former to current smokers. Furthermore, former and never smokers had significantly lower CVD event rates compared with current smokers [hazard ratio 0.70 (95% CI 0.51, 0.95), P = 0.02 and 0.48 (0.34, 0.69), P < 0.001, respectively]. The CVD event rates for former and never smokers were comparable. Conclusion: Smoking cessation in patients with RA was associated with lower disease activity and improved lipid profiles and was a predictor of reduced rates of CVD events

A Meta-Analysis and Genome-Wide Association Study of Platelet Count and Mean Platelet Volume in African Americans

Several genetic variants associated with platelet count and mean platelet volume (MPV) were recently reported in people of European ancestry. In this meta-analysis of 7 genome-wide association studies (GWAS) enrolling African Americans, our aim was to identify novel genetic variants associated with platelet count and MPV. For all cohorts, GWAS analysis was performed using additive models after adjusting for age, sex, and population stratification. For both platelet phenotypes, meta-analyses were conducted using inverse-variance weighted fixed-effect models. Platelet aggregation assays in whole blood were performed in the participants of the GeneSTAR cohort. Genetic variants in ten independent regions were associated with platelet count (N = 16,388) with p<5×10−8 of which 5 have not been associated with platelet count in previous GWAS. The novel genetic variants associated with platelet count were in the following regions (the most significant SNP, closest gene, and p-value): 6p22 (rs12526480, LRRC16A, p = 9.1×10−9), 7q11 (rs13236689, CD36, p = 2.8×10−9), 10q21 (rs7896518, JMJD1C, p = 2.3×10−12), 11q13 (rs477895, BAD, p = 4.9×10−8), and 20q13 (rs151361, SLMO2, p = 9.4×10−9). Three of these loci (10q21, 11q13, and 20q13) were replicated in European Americans (N = 14,909) and one (11q13) in Hispanic Americans (N = 3,462). For MPV (N = 4,531), genetic variants in 3 regions were significant at p<5×10−8, two of which were also associated with platelet count. Previously reported regions that were also significant in this study were 6p21, 6q23, 7q22, 12q24, and 19p13 for platelet count and 7q22, 17q11, and 19p13 for MPV. The most significant SNP in 1 region was also associated with ADP-induced maximal platelet aggregation in whole blood (12q24). Thus through a meta-analysis of GWAS enrolling African Americans, we have identified 5 novel regions associated with platelet count of which 3 were replicated in other ethnic groups. In addition, we also found one region associated with platelet aggregation that may play a potential role in atherothrombosis

Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial

Background: Postoperative pulmonary complications (PPCs) increase the morbidity and mortality of surgery in obese patients. High levels of positive end-expiratory pressure (PEEP) with lung recruitment maneuvers may improve intraoperative respiratory function, but they can also compromise hemodynamics, and the effects on PPCs are uncertain. We hypothesized that intraoperative mechanical ventilation using high PEEP with periodic recruitment maneuvers, as compared with low PEEP without recruitment maneuvers, prevents PPCs in obese patients. Methods/design The PRotective Ventilation with Higher versus Lower PEEP during General Anesthesia for Surgery in OBESE Patients (PROBESE) study is a multicenter, two-arm, international randomized controlled trial. In total, 2013 obese patients with body mass index ≥35 kg/m2 scheduled for at least 2 h of surgery under general anesthesia and at intermediate to high risk for PPCs will be included. Patients are ventilated intraoperatively with a low tidal volume of 7 ml/kg (predicted body weight) and randomly assigned to PEEP of 12 cmH2O with lung recruitment maneuvers (high PEEP) or PEEP of 4 cmH2O without recruitment maneuvers (low PEEP). The occurrence of PPCs will be recorded as collapsed composite of single adverse pulmonary events and represents the primary endpoint. Discussion To our knowledge, the PROBESE trial is the first multicenter, international randomized controlled trial to compare the effects of two different levels of intraoperative PEEP during protective low tidal volume ventilation on PPCs in obese patients. The results of the PROBESE trial will support anesthesiologists in their decision to choose a certain PEEP level during general anesthesia for surgery in obese patients in an attempt to prevent PPCs. Trial registration ClinicalTrials.gov identifier: NCT02148692. Registered on 23 May 2014; last updated 7 June 2016. Electronic supplementary material The online version of this article (doi:10.1186/s13063-017-1929-0) contains supplementary material, which is available to authorized users