12 research outputs found

    Beginning with Our Voices: How the Experiential Stories of First Nations Women Contribute to a National Research Project

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    The purpose of this paper is to review how the experiential stories of First Nations women contribute to a national research project. The project focuses on how women’s healing is impacted by their views about themselves as - and the stigma associated with being - a drug user, involved in crime and an Aboriginal woman.Our project began with three First Nations women on our research team documenting the role of stigma and self-identity in their personal healing journeys from problematically using drugs and being in conflict with the law. In this paper we discuss how key components of feminist research practices, Aboriginal methodology and community-based research helped us position the women’s experiential stories in authoritative, recognized and celebrated ways in our study. We illustrate how the women’s stories uniquely contributed to the creation of our interview questions and the research project in general. We also discuss how the women personally benefited from writing about and sharing their experiences. Key benefits include the women discovering the impact of the written word, promotion of their healing, personal recognition of their ability to offer hope to women in need, increased self-esteem, and increased appreciation of the importance of sharing their lived experiences with others. Our method of research differs from a conventional western scientific approach to understanding, and as such made important contributions to both the project itself and the women who shared their experiential stories

    Nitsiyihkâson: The Brain Science behind Cree Teachings of Early Childhood Attachment

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    The Nitsiyihkâson project was conceived in order to develop a resource to promote attachment and development in a manner culturally appropriate to the Indigenous (specifically Cree) people of Alberta. Promoting secure attachment between a child and his/her caregivers is crucial to ensuring positive mental health, and improving family well-being. Working collaboratively with the community of Saddle Lake, the process began by launching the project in traditional ceremony. Following this, a talking circle was held with Saddle Lake Elders to share their memories and understanding of child-rearing practices that promote attachment. Using their guidance, we produced the document “awina kiyanaw”, which focuses on Cree stories and teachings, for parents to share with their young children. This document will be shared within the community, and agencies interested in promoting a culturally-appropriate approach to parenting. We then examined the cross-cultural applicability of these practices and produced a Resource Manual for service providers, comparing traditional ways-of-knowing with current neurobiological and epigenetic scientific understanding. We believe this helps those working with Indigenous families better understand their culture, and appreciate the wisdom in its teachings. In this paper, we present those findings and their ramifications

    Nitsiyihkâson: The Brain Science Behind Cree Teachings of Early Childhood Attachment

    No full text
    The Nitsiyihkâson project was conceived in order to develop a resource to promote attachment and development in a manner culturally appropriate to the Indigenous (specifically Cree) people of Alberta. Promoting secure attachment between a child and his/her caregivers is crucial to ensuring positive mental health, and improving family well-being. Working collaboratively with the community of Saddle Lake, the process began by launching the project in traditional ceremony. Following this, a talking circle was held with Saddle Lake Elders to share their memories and understanding of child-rearing practices that promote attachment. Using their guidance, we produced the document “awina kiyanaw”, which focuses on Cree stories and teachings, for parents to share with their young children. This document will be shared within the community, and agencies interested in promoting a culturally-appropriate approach to parenting. We then examined the cross-cultural applicability of these practices and produced a Resource Manual for service providers, comparing traditional ways-of-knowing with current neurobiological and epigenetic scientific understanding. We believe this helps those working with Indigenous families better understand their culture, and appreciate the wisdom in its teachings. In this paper, we present those findings and their ramifications

    Multicenter Evaluation of BioFire FilmArray Meningitis/Encephalitis Panel for Detection of Bacteria, Viruses, and Yeast in Cerebrospinal Fluid Specimens.

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    Rapid diagnosis and treatment of infectious meningitis and encephalitis are critical to minimize morbidity and mortality. Comprehensive testing of cerebrospinal fluid (CSF) often includes Gram stain, culture, antigen detection, and molecular methods, paired with chemical and cellular analyses. These methods may lack sensitivity or specificity, can take several days, and require significant volume for complete analysis. The FilmArray Meningitis/Encephalitis (ME) Panel is a multiplexed in vitro diagnostic test for the simultaneous, rapid (∼1-h) detection of 14 pathogens directly from CSF specimens: Escherichia coli K1, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitidis, Streptococcus pneumoniae, Streptococcus agalactiae, cytomegalovirus, enterovirus, herpes simplex virus 1 and 2, human herpesvirus 6, human parechovirus, varicella-zoster virus, and Cryptococcus neoformans/Cryptococcus gattii We describe a multicenter evaluation of 1,560 prospectively collected CSF specimens with performance compared to culture (bacterial analytes) and PCR (all other analytes). The FilmArray ME Panel demonstrated a sensitivity or positive percentage of agreement of 100% for 9 of 14 analytes. Enterovirus and human herpesvirus type 6 had agreements of 95.7% and 85.7%, and L. monocytogenes and N. meningitidis were not observed in the study. For S. agalactiae, there was a single false-positive and false-negative result each, for a sensitivity and specificity of 0 and 99.9%, respectively. The specificity or negative percentage of agreement was 99.2% or greater for all other analytes. The FilmArray ME Panel is a sensitive and specific test to aid in diagnosis of ME. With use of this comprehensive and rapid test, improved patient outcomes and antimicrobial stewardship are anticipated

    Identifying and Visualizing Macromolecular Flexibility in Structural Biology

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