122 research outputs found
First direct observation of two protons in the decay of Fe with a TPC
The decay of the ground-state two-proton emitter 45Fe was studied with a
time-projection chamber and the emission of two protons was unambiguously
identified. The total decay energy and the half-life measured in this work
agree with the results from previous experiments. The present result
constitutes the first direct observation of the individual protons in the
two-proton decay of a long-lived ground-state emitter. In parallel, we
identified for the first time directly two-proton emission from 43Cr, a known
beta-delayed two-proton emitter. The technique developped in the present work
opens the way to a detailed study of the mechanism of ground-state as well as
beta-delayed two-proton radioactivity.Comment: 4 pages, 5 figure
Investigation of the 6He cluster structures
The 4He+2n and t+t clustering of the 6He ground state were investigated by
means of the transfer reaction 6He(p,t)4He at 25 MeV/nucleon. The experiment
was performed in inverse kinematics at GANIL with the SPEG spectrometer coupled
to the MUST array. Experimental data for the transfer reaction were analyzed by
a DWBA calculation including the two neutrons and the triton transfer. The
couplings to the 6He --> 4He + 2n breakup channels were taken into account with
a polarization potential deduced from a coupled-discretized-continuum channels
analysis of the 6He+1H elastic scattering measured at the same time. The
influence on the calculations of the 4He+t exit potential and of the triton
sequential transfer is discussed. The final calculation gives a spectroscopic
factor close to one for the 4He+2n configuration as expected. The spectroscopic
factor obtained for the t+t configuration is much smaller than the theoretical
predictions.Comment: 10 pages, 11 figures, accepted in PR
The N=14 shell closure in O viewed through a neutron sensitive probe
NESTER PTHInternational audienceTo investigate the behavior of the N=14 neutron gap far from stability with a neutron-sensitive probe, proton elastic and 2+1 inelastic scattering angular distributions for the neutron-rich nucleus 22O were measured with a secondary beam intensity of only 1200 particles per second using the MUST silicon strip detector array at the GANIL facility. A phenomenological analysis yields a deformation parameter bp;p' = 0.26 +- 0.04 for the 2+1 state, much lower than in 20O, showing a surprisingly weak neutron contribution to this state. A fully microscopic analysis was performed using optical potentials obtained from matter and transition densities generated by continuum Skyrme-HFB and QRPA calculations, respectively. When the present results and those from a 22O + 197Au scattering experiment are combined, the ratio of neutron to proton contributions to the 2+1 state is found close to the N/Z ratio, demonstrating a strong N=14 shell closure in the vicinity of the neutron drip-line
Inverse kinematics proton scattering from the exotic nucleus O
NESTER PTHInternational audienceWe have measured for the first time elastic and inelastic proton scattering from the neutron rich nucleus 22O at 46.6 AMeV using the MUST array
MAYA: An active-target detector for binary reactions with exotic beams
International audienceWith recent improvements in the production of radioactive beams in facilities such as SPIRAL at GANIL, a larger area of the nuclear chart is now accessible for experimentation. For these usually low-intensity and low-energy secondary beams, we have developed the new MAYA detector based on the active-target concept. This device allows to use a relatively thick target without loss of resolution by using the detection gas as target material. Dedicated 3D tracking, particle identification, energy loss and range measurements allow complete kinematic reconstruction of reactions taking place inside MAYA
Ion slowing down and charge exchange at small impact parameters selected by channeling: superdensity effects
CASInternational audienceIn two experiments performed with 20-30 MeV/u highly charged heavy ions (Pb56+, U91+) channeled through thin silicon crystals, we observed the original features of superdensity, associated to the glancing collisions with atomic rows undergone by part of the incident projectiles. In particular the very high collision rate yields a quite specific charge exchange regime, that leads to a higher ionization probability than in random conditions. X-ray measurements show that electrons captured in outershells are prevented from being stabilized, which enhances the lifetime of the projectile innershell vacancies. The charge state distributions and the energy loss spectra are compared to Monte-Carlo simulations. These simulations confirm, extend and illustrate the qualitative analysis of the experimental results
Study of Na at SPIRAL
NESTERInternational audienceThe excitation function for the elastic-scattering reaction p18Ne, p18Ne was measured with the first radioactive beam from the SPIRAL facility at the GANIL laboratory and with a solid cryogenic hydrogen target. Several broad resonances have been observed, corresponding to new excited states in the unbound nucleus 19Na. In addition, two-proton emission events have been identified and are discussed
A systematic review of clinical decision support systems for antimicrobial management: are we failing to investigate these interventions appropriately?
Objectives
Clinical decision support systems (CDSS) for antimicrobial management can support clinicians to optimize antimicrobial therapy. We reviewed all original literature (qualitative and quantitative) to understand the current scope of CDSS for antimicrobial management and analyse existing methods used to evaluate and report such systems.
Method
PRISMA guidelines were followed. Medline, EMBASE, HMIC Health and Management and Global Health databases were searched from 1 January 1980 to 31 October 2015. All primary research studies describing CDSS for antimicrobial management in adults in primary or secondary care were included. For qualitative studies, thematic synthesis was performed. Quality was assessed using Integrated quality Criteria for the Review Of Multiple Study designs (ICROMS) criteria. CDSS reporting was assessed against a reporting framework for behaviour change intervention implementation.
Results
Fifty-eight original articles were included describing 38 independent CDSS. The majority of systems target antimicrobial prescribing (29/38;76%), are platforms integrated with electronic medical records (28/38;74%), and have a rules-based infrastructure providing decision support (29/38;76%). On evaluation against the intervention reporting framework, CDSS studies fail to report consideration of the non-expert, end-user workflow. They have narrow focus, such as antimicrobial selection, and use proxy outcome measures. Engagement with CDSS by clinicians was poor.
Conclusion
Greater consideration of the factors that drive non-expert decision making must be considered when designing CDSS interventions. Future work must aim to expand CDSS beyond simply selecting appropriate antimicrobials with clear and systematic reporting frameworks for CDSS interventions developed to address current gaps identified in the reporting of evidence
A cross-sectional study of blood cultures and antibiotic use in patients admitted from the Emergency Department: missed opportunities for antimicrobial stewardship
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