Program Peningkatan Kemampuan Guru Dalam Pembelajaran Bahasa Jawa Di SD Patemon 01 Dan SD Sekaran 01 Kecamatan Gunungpati Kota Semarang

Learning Javanese language has been starting on since a long time, but still there are some problems found in the field. Problems when learning Javanese language that occur in SD Patemon 01 and SD Sekaran 01, District Gunungpati, Semarang are (1) low capacity of the teachers in creating computer-based learning media, (2) lack of language skills of the teachers in using Javanese language variety of manners, and (3) frequent occurrence of errors in the assessment of learning Javanese language. In connection with these conditions, devotee team tried to be facilitators to the problems faced by teachers in SD Patemon 01 and SD Sekaran 01 by conducting science and technology activities for the Community (IbM). IbM program implementation used workshop model with a variety of methods, such as lecturing, demonstrations, direct practice, frequently asked questions and assignments. The results of this IbM program are capacity building of teachers in making computers-based learning media for Javanese language, improving the competence of teachers in terms of manners of Javanese language skills, and increaseing understanding of Javanese language learning assessment. The increase was indicated from abilities\u27 score of the teachers before and after the IbM program. The ability of teachers in terms of making computer-based instructional media increased significantly, ie 16.9%. Competence of teachers in terms of unggah-ungguh based on Javanese language, especially in speaking skills manners increased 6.3%. The ability of teachers in terms of understanding of the Java language learning assessment increased 9.7%

Students ’ Pre-Departure Expectations and Post-Sojourn Observations in a Short-Term International Program Abroad on the Culture, Music, and Art of Brazil

Using data obtained from 15 students at a major Northeastern university, the writer examined a short-term international program abroad on Brazilian culture and art. She presents results on program students\u27 predeparture expectations and postsojourn observations and on program benefits

An individual based computational model of intestinal crypt fission and its application to predicting unrestrictive growth of the intestinal epithelium.

Intestinal crypt fission is a homeostatic phenomenon, observable in healthy adult mucosa, but which also plays a pathological role as the main mode of growth of some intestinal polyps. Building on our previous individual based model for the small intestinal crypt and on in vitro cultured intestinal organoids, we here model crypt fission as a budding process based on fluid mechanics at the individual cell level and extrapolated predictions for growth of the intestinal epithelium. Budding was always observed in regions of organoids with abundant Paneth cells. Our data support a model in which buds are biomechanically initiated by single stem cells surrounded by Paneth cells which exhibit greater resistance to viscoelastic deformation, a hypothesis supported by atomic force measurements of single cells. Time intervals between consecutive budding events, as simulated by the model and observed in vitro, were 2.84 and 2.62 days, respectively. Predicted cell dynamics was unaffected within the original crypt which retained its full capability of providing cells to the epithelium throughout fission. Mitotic pressure in simulated primary crypts forced upward migration of buds, which simultaneously grew into new protruding crypts at a rate equal to 1.03 days-1 in simulations and 0.99 days-1 in cultured organoids. Simulated crypts reached their final size in 4.6 days, and required 40 6.2 days to migrate to the top of the primary crypt. The growth of the secondary crypt is independent of its migration along the original crypt. Assuming unrestricted crypt fission and multiple budding events, a maximal growth rate of the intestinal epithelium of 0.10 days-1 43 is predicted and thus approximately 22 days are required for a 10-fold increase of polyp size. These predictions are in agreement with the time reported to develop macroscopic adenomas in mice after loss of Apc in intestinal stem cells

Depletion of enteric bacteria diminishes leukocyte infiltration following doxorubicin-induced small intestinal damage in mice

While enteric bacteria have been shown to play a critical role in other forms of intestinal damage, their role in mediating the response to the chemotherapeutic drug Doxorubicin (Doxo) is unclear. In this study, we used a mouse model of intestinal bacterial depletion to evaluate the role enteric bacteria play in mediating Doxo-induced small intestinal damage and, more specifically, in mediating chemokine expression and leukocyte infiltration following Doxo treatment. An understanding of this pathway may allow for development of intervention strategies to reduce chemotherapy-induced small intestinal damage