7,852 research outputs found

    Openness, Similarity in Export Composition and Income Dynamics

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    2A relevant share of the theoretical and empirical analysis on economic growth has been devoted to finding a specific role for international trade in reinforcing countries’ growth rates. Not as much attention has been dedicated to the role of sectoral composition of export in influencing the effect of trade on income convergence. In this paper we look at this issue along the line of research on multiple regimes and convergence clubs, considering how openness and similarity in export composition among countries can induce convergence in income levels among the same countries. We apply our analysis to the catching-up of income levels of Central and Eastern Europe Countries to the EU benchmark. We explicitly consider the sectoral export patterns of the CEECs by comparing them to those of the 15 old members of the EU, focusing on countries’ specialization as suppliers for the EU market. Our main result is that similarity in export composition has a positive, significant and nonlinear impact on catching-up. Results are robust to controlling for openness and country-size and for investment, schooling, and the quality of institutions.openL. DE BENEDICTIS; TAJOLI LDE BENEDICTIS, Luca; Tajoli, L

    Simulating the formation of a proto-cluster at z~2

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    We present results from two high-resolution hydrodynamical simulations of proto-cluster regions at z~2.1. The simulations have been compared to observational results for the socalled Spiderweb galaxy system, the core of a putative proto-cluster region at z = 2.16, found around a radio galaxy. The simulated regions have been chosen so as to form a poor cluster with M200~10^14 h-1 Msun (C1) and a rich cluster with M200~2x10^15 h-1 Msun (C2) at z = 0. The simulated proto-clusters show evidence of ongoing assembly of a dominating central galaxy. The stellar mass of the brightest cluster galaxy (BCG) of the C2 system is in excess with respect to observational estimates for the Spiderweb galaxy, with a total star formation rate which is also larger than indicated by observations. We find that the projected velocities of galaxies in the C2 cluster are consistent with observations, while those measured for the poorer cluster C1 are too low compared to the observed velocities. We argue that the Spiderweb complex resemble the high-redshift progenitor of a rich galaxy cluster. Our results indicate that the included supernovae feedback is not enough to suppress star formation in these systems, supporting the need of introducing AGN feedback. According to our simulations, a diffuse atmosphere of hot gas in hydrostatic equilibrium should already be present at this redshift, and enriched at a level comparable to that of nearby galaxy clusters. The presence of this gas should be detectable with future deep X-ray observations.Comment: 6 pages, 4 figures, accepted for publication in MNRAS (Letters

    A topological approach to neural complexity

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    Considerable efforts in modern statistical physics is devoted to the study of networked systems. One of the most important example of them is the brain, which creates and continuously develops complex networks of correlated dynamics. An important quantity which captures fundamental aspects of brain network organization is the neural complexity C(X)introduced by Tononi et al. This work addresses the dependence of this measure on the topological features of a network in the case of gaussian stationary process. Both anlytical and numerical results show that the degree of complexity has a clear and simple meaning from a topological point of view. Moreover the analytical result offers a straightforward algorithm to compute the complexity than the standard one.Comment: 6 pages, 4 figure

    Comparison of the VIMOS-VLT Deep Survey with the Munich semi-analytical model. II. The colour-density relation up to z=1.5

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    [Abridged] We perform on galaxy mock catalogues the same colour-density analysis made by Cucciati et al. (2006) on a 5 Mpc/h scale using the VVDS-Deep survey, and compare the results from mocks with observed data. We use mocks with the same flux limits (I=24) as the VVDS (CMOCKS), built using the semi- analytic model by De Lucia & Blaizot (2007) applied to the Millennium Simulation. From CMOCKS, we extracted samples of galaxies mimicking the VVDS observational strategy (OMOCKS). We computed the B-band Luminosity Function LF and the colour-density relation (CDR) in the mocks. We find that the LF in mocks roughly agrees with the observed LF, but at z<0.8 the faint-end slope of the model LF is steeper than the VVDS one. Computing the LF for early and late type galaxies, we show that mocks have an excess of faint early-type and of bright late-type galaxies with respect to data. We find that the CDR in OMOCKS is in excellent agreement with the one in CMOCKS. At z~0.7, the CDR in mocks agrees with the VVDS one (red galaxies reside mainly in high densities). Yet, the strength of the CDR in mocks does not vary within 0.2<z<1.5, while the observed relation flattens with increasing z and possibly inverts at z=1.3. We argue that the lack of evolution in the CDR in mocks is not due only to inaccurate prescriptions for satellite galaxies, but that also the treatment of central galaxies has to be revised. The reversal of the CDR can be explained by wet mergers between young galaxies, producing a starburst event. This should be seen on group scales. A residual of this is found in observations at z=1.5 on larger scales, but not in the mocks, suggesting that the treatment of physical processes affecting satellites and central galaxies in models should be revised.Comment: 15 pages, 12 figures, accepted for publication in A&

    E-ABR in patients with cochlear implant: A comparison between patients with malformed cochlea and normal cochlea

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    OBJECTIVES: This study aims to compare the electrical auditory brainstem response (EABR) following cochlear implant (CI) surgery in pediatric subjects with cochlear malformation and a normal cochlea, in order to assess the sensitivity of EABR and to evaluate the surgery outcome. MATERIALS and METHODS: A total of 26 pediatric subjects who were deaf and scheduled for CI surgery were enrolled into this case control study. Group A (n=20) included subjects with a normo-conformed cochlea. Group B (n=6) included subjects with cochlear malformation. Subjects were evaluated with EABR immediately (T0) and 6 months (T1) post-CI surgery. The EABR Waves III and V average amplitude and latency were compared across time, separately for each group, and across groups, separately for each time. RESULTS: Auditory brainstem response (ABR) could only be recorded in Group A. We were able to record EABR from all subjects at T0 and T1, and waves III and V were present in all the recorded signals. There were no statistically significant differences between T0 and T1 in EABR Waves III and V in terms of average amplitude and latency in neither group. When comparing Groups A and B, the only statistically significant difference was the average amplitude of wave V, both at T0 and T1. CONCLUSION: EABR is a valid tool to measure the auditory nerve integrity after CI surgery in patients with a normal and malformed cochlea, as shown by its ability to measure waves III and V when ABR is absent. The EABR testing should be performed before and after CI surgery, and EABR should be used as a measure of outcome, especially in patients with a malformed cochlea

    Like grandparents, like parents: Empirical evidence and psychoanalytic thinking on the transmission of parenting styles

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    The authors discuss the issue of intergenerational transmission of parenting from an empirical and psychoanalytic perspective. After presenting a framework to explain their conception of parenting, they describe intergenerational transmission of parenting as a key to interpreting and eventually changing parenting behaviors. Then they present (1) the empirical approach aimed at determining if there is actually a stability across generations that contributes to harsh parenting and eventually maltreatment and (2) the psyphoanalytic thinking that seeks to explain the continuity in terms of representations and clinical phenomena. The authors also discuss the relationship between the attachment and the caregiving systems and hypothesize a common base for the two systems in childhood experience. Finally, they propose the psychoanalytic perspective as a fruitful theoretical framework to integrate the evidence for the neurophysiological mediators and moderators of intergenerational transmission. Psychoanalytically informed research can provide clinically relevant insights and hypotheses to be tested

    Short-Term Orchestral Music Training Modulates Hyperactivity and Inhibitory Control in School-Age Children: A Longitudinal Behavioural Study

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    Survey studies have shown that participating in music groups produces several benefits, such as discipline, cooperation and responsibility. Accordingly, recent longitudinal studies showed that orchestral music training has a positive impact on inhibitory control in school-age children. However, most of these studies examined long periods of training not always feasible for all families and institutions and focused on children’s measures ignoring the viewpoint of the teachers. Considering the crucial role of inhibitory control on hyperactivity, inattention and impulsivity, we wanted to explore if short orchestral music training would promote a reduction of these impulsive behaviors in children. This study involved 113 Italian children from 8 to 10 years of age. 55 of them attended 3 months of orchestral music training. The training included a 2-hour lesson per week at school and a final concert. The 58 children in the control group did not have any orchestral music training. All children were administered tests and questionnaires measuring inhibitory control and hyperactivity near the beginning and end of the 3-month training period. We also collected information regarding the levels of hyperactivity of the children as perceived by the teachers at both time points. Children in the music group showed a significant improvement in inhibitory control. Moreover, in the second measurement the control group showed an increase in self-reported hyperactivity that was not found in the group undergoing the music training program. This change was not noticed by the teachers, implying a discrepancy between self-reported and observed behavior at school. Our results suggest that even an intense and brief period of orchestral music training is sufficient to facilitate the development of inhibitory control by modulating the levels of self-reported hyperactivity. This research has implications for music pedagogy and education especially in children with high hyperactivity. Future investigations will test whether the findings can be extended to children diagnosed with ADHD

    Effects of asphericity and substructure on the determination of cluster mass with weak gravitational lensing

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    Weak gravitational lensing can be used to directly measure the mass along a line-of-sight without any dependence on the dynamical state of the mass, and thus can be used to measure the masses of clusters even if they are not relaxed. One common technique used to measure cluster masses is fitting azimuthally-averaged gravitational shear profiles with a spherical mass model. In this paper we quantify how asphericity and projected substructure in clusters can affect the virial mass and concentration measured with this technique by simulating weak lensing observations on 30 independent lines-of-sights through each of four high-resolution N-body cluster simulations. We find that the variations in the measured virial mass and concentration are of a size similar to the error expected in ideal weak lensing observations and are correlated, but that the virial mass and concentration of the mean shear profile agree well with that measured in three dimensional models of the clusters. The dominant effect causing the variations is the proximity of the line-of-sight to the major axis of the 3-D cluster mass distribution, with projected substructure only causing minor perturbations in the measured concentration. Finally we find that the best-fit "universal" CDM models used to fit the shear profiles over-predict the surface density of the clusters due to the cluster mass density falling off faster than the r^{-3} model assumption.Comment: 10 pages, 10 figures, accepted by MNRA

    Pepducin-mediated cardioprotection via β-arrestin-biased β2-adrenergic receptor-specific signaling

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    Reperfusion as a therapeutic intervention for acute myocardial infarction-induced cardiac injury itself induces further cardiomyocyte death. β-arrestin (βarr)-biased β-adrenergic receptor (βAR) activation promotes survival signaling responses in vitro; thus, we hypothesize that this pathway can mitigate cardiomyocyte death at the time of reperfusion to better preserve function. However, a lack of efficacious βarr-biased orthosteric small molecules has prevented investigation into whether this pathway relays protection against ischemic injury in vivo. We recently demonstrated that the pepducin ICL1-9, a small lipidated peptide fragment designed from the first intracellular loop of β2AR, allosterically engaged pro-survival signaling cascades in a βarr-dependent manner in vitro. Thus, in this study we tested whether ICL1-9 relays cardioprotection against ischemia/reperfusion (I/R)-induced injury in vivo. Methods: Wild-type (WT) C57BL/6, β2AR knockout (KO), βarr1KO and βarr2KO mice received intracardiac injections of either ICL1-9 or a scrambled control pepducin (Scr) at the time of ischemia (30 min) followed by reperfusion for either 24 h, to assess infarct size and cardiomyocyte death, or 4 weeks, to monitor the impact of ICL1-9 on long-term cardiac structure and function. Neonatal rat ventricular myocytes (NRVM) were used to assess the impact of ICL1-9 versus Scr pepducin on cardiomyocyte survival and mitochondrial superoxide formation in response to either serum deprivation or hypoxia/reoxygenation (H/R) in vitro and to investigate the associated mechanism(s). Results: Intramyocardial injection of ICL1-9 at the time of I/R reduced infarct size, cardiomyocyte death and improved cardiac function in a β2AR- and βarr-dependent manner, which led to improved contractile function early and less fibrotic remodeling over time. Mechanistically, ICL1-9 attenuated mitochondrial superoxide production and promoted cardiomyocyte survival in a RhoA/ROCK-dependent manner. RhoA activation could be detected in cardiomyocytes and whole heart up to 24 h post-treatment, demonstrating the stability of ICL1-9 effects on βarr-dependent β2AR signaling. Conclusion: Pepducin-based allosteric modulation of βarr-dependent β2AR signaling represents a novel therapeutic approach to reduce reperfusion-induced cardiac injury and relay long-term cardiac remodeling benefits

    issues on the modal characterization of large monumental structures with complex dynamic interactions

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    Abstract Vibration-based monitoring techniques are currently used for damage assessment especially in monumental structures. In fact, dynamic tests allow investigation of structural behaviour of the building system through minimally invasive actions, which is important when preservation of the integrity of historical buildings is required. The Sanctuary of Vicoforte (Cuneo, Italy) has great architectural significance and contains the largest masonry oval dome in the world (axes 37.15 m × 24.80 m). The first dynamic campaign on this monumental building was performed in 2008. During this campaign, ambient vibrations could be measured in a limited portion of the oval dome, hence a first dynamic characterization was accomplished thanks to a recursive model-driven procedure. Some of the identified values were considered uncertain because the setups that were not able to fully capture the global behaviour. In 2015, a permanent dynamic monitoring system was installed on the dome-drum area of the building through Optimal Sensor Placement (OSP) procedures. New ambient response data were analysed in order to better define the dynamic properties of the structure as a whole, considering possible dynamic interactions. The most recent identification sessions, while retrieving and confirming the main results obtained in 2008, also supply elements that could not be appreciated in the first dynamic campaign. In any event, the Basilica's dynamic characterization requires very complex data processing and modelling operations due to the presence of dynamic interaction both with the soil and with other elements of the structure, and because of uncertainties about mass and material properties. This paper summarises the process that has finally led to the dynamic characterization of this stunning architectural structure
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