Music as soft power: the electoral use of spotify

The changes brought by new technologies and the ensuing rapid development of the communication field have resulted in an increasing number of studies on politicians’ use of the internet and social media. However, while election campaigns have been the predominant research area in political communication scholarship, music has not yet been taken as an object of study alongside spectacularisation and politainment. Aside from some preliminary studies, systematic research on music in politics is scarce. The literature holds that music is a universal language. Music in politics can therefore be deemed to be an identification tool that can help politicians connect with voters and bring together positions between the different actors of international relations. This is an exploratory study about the use of music in political campaigning. It is focused on the role played by the Spotify playlists created by the main political parties in recent election campaigns in Spain. The initial hypothesis is that some of the candidates strategically selected songs to be shared with their followers. A quantitative content analysis (N = 400) of some Spotify playlists showed that there were significant differences in the selection of songs among the different political parties. This research contributes to the understanding of how Spotify has been used for electoral campaigning, as well as shedding some light on the current communication literature on music and politics

Nucleation and Crystallization of PA6 Composites Prepared by T-RTM: Effects of Carbon and Glass Fiber Loading

Thermoplastic resin transfer molding (T-RTM) is attracting much attention due to the need for recyclable alternatives to thermoset materials. In this work, we have prepared polyamide-6 (PA6) and PA6/fiber composites by T-RTM of caprolactam. Glass and carbon fibers were employed in a fixed amount of 60 and 47 wt.%, respectively. Neat PA6 and PA6 matrices (of PA6-GF and PA6-CF) of approximately 200 kg/mol were obtained with conversion ratios exceeding 95%. Both carbon fibers (CF) and glass fibers (GF) were able to nucleate PA6, with efficiencies of 44% and 26%, respectively. The α crystal polymorph of PA6 was present in all samples. The lamellar spacing, lamellar thickness and crystallinity degree did not show significant variations in the samples with or without fibers as result of the slow cooling process applied during T-RTM. The overall isothermal crystallization rate decreased in the order: PA6-CF > PA6-GF > neat PA6, as a consequence of the different nucleation efficiencies. The overall crystallization kinetics data were successfully described by the Avrami equation. The lamellar stack morphology observed by atomic force microscopy (AFM) is consistent with 2D superstructural aggregates (n = 2) for all samples. Finally, the reinforcement effect of fibers was larger than one order of magnitude in the values of elastic modulus and tensile strength.We gratefully acknowledge the Basque Government by the funding received through the ELKARTEK 2017 Cooperative Fundamental Research project: ”Automotion Composites fabricated by RTM adapted to the 4.0 industrial philosophy (RTM4.0). The authors thank the ALBA Synchrotron Light facility for supporting the X-rays experiments at beamline BL11-NCD-SWEET and the funding by ALBA project nº 2017092338. The UPV/EHU team gratefully acknowledges the financial contribution of the Basque Government through grant IT1309-19

BIRI: a new approach for automatically discovering and indexing available public bioinformatics resources from the literature

<p>Abstract</p> <p>Background</p> <p>The rapid evolution of Internet technologies and the collaborative approaches that dominate the field have stimulated the development of numerous bioinformatics resources. To address this new framework, several initiatives have tried to organize these services and resources. In this paper, we present the BioInformatics Resource Inventory (BIRI), a new approach for automatically discovering and indexing available public bioinformatics resources using information extracted from the scientific literature. The index generated can be automatically updated by adding additional manuscripts describing new resources. We have developed web services and applications to test and validate our approach. It has not been designed to replace current indexes but to extend their capabilities with richer functionalities.</p> <p>Results</p> <p>We developed a web service to provide a set of high-level query primitives to access the index. The web service can be used by third-party web services or web-based applications. To test the web service, we created a pilot web application to access a preliminary knowledge base of resources. We tested our tool using an initial set of 400 abstracts. Almost 90% of the resources described in the abstracts were correctly classified. More than 500 descriptions of functionalities were extracted.</p> <p>Conclusion</p> <p>These experiments suggest the feasibility of our approach for automatically discovering and indexing current and future bioinformatics resources. Given the domain-independent characteristics of this tool, it is currently being applied by the authors in other areas, such as medical nanoinformatics. BIRI is available at <url>http://edelman.dia.fi.upm.es/biri/</url>.</p

Guía de recursos para la investigación antropológica.

Sin resume

e-MIR2: a public online inventory of medical informatics resources

Background. Over the last years, the number of available informatics resources in medicine has grown exponentially. While specific inventories of such resources have already begun to be developed for Bioinformatics (BI), comparable inventories are as yet not available for Medical Informatics (MI) field, so that locating and accessing them currently remains a hard and time-consuming task. Description. We have created a repository of MI resources from the scientific literature, providing free access to its contents through a web-based service. Relevant information describing the resources is automatically extracted from manuscripts published in top-ranked MI journals. We used a pattern matching approach to detect the resources? names and their main features. Detected resources are classified according to three different criteria: functionality, resource type and domain. To facilitate these tasks, we have built three different taxonomies by following a novel approach based on folksonomies and social tagging. We adopted the terminology most frequently used by MI researchers in their publications to create the concepts and hierarchical relationships belonging to the taxonomies. The classification algorithm identifies the categories associated to resources and annotates them accordingly. The database is then populated with this data after manual curation and validation. Conclusions. We have created an online repository of MI resources to assist researchers in locating and accessing the most suitable resources to perform specific tasks. The database contained 282 resources at the time of writing. We are continuing to expand the number of available resources by taking into account further publications as well as suggestions from users and resource developers

Prevalencia del Helicobacter pylori mediante Elisa en estudiantes de la Facultad de Odontología de la Universidad de San Marcos

With the objective of prove the prevalence of the Helicobacter pylori (flp) in odontology students and establish the relation between the positive seroreactors and related symptomatologies to Hp, like: stress, gastritis, ulcer and cancer it was selected a random population sample of 91 students between 15-24 years old, for the detection of IgG antibodies in sera using the Kit Platelia R. To the same population sample ¡t was applied a personal information form lo be filled by the students. Front a total of 91 students that have finished the study, ¡t was founded a general seroprevalence of the Hp in 72,5 % (66/91), with sexual prevalence of 68,3 and 76 %, in women and men, respectively. At the time of relate the personal information, with the positive seroreactors, it was founded that: the 73,1 % (19/26) have stress, 61,5 % (8/13) have gastritis y 100 % (2/2) have ulcer. With regard to the symptomatologies in the student of the sample, it was founded that: the 28,6 % (26/91) have stress, 14,3 % (13/91) have gastritis y 2,2 % (2/91) have ulcer In relation of the symptomatologies in the students familiars, ¡t was founded that the 33 % (30/91) have gastritis, 18,7 % (17/91) have ulcer and a 5,5 % (5/91) have cancer It was concluded that the 72,5 % of the de positive seroreactors are between the rank of Hp seroprevalence of the countries in development; that there is a high relation (&gt; 60 %) of ~ositive seroreactors with registered symptomatologies in the forms, like: stress, gastritis and ulcer; in the same manner it reveal sequestered numbers of the presence of these symptomatologies in the students, and these in relation with their familiars, nevertheless, the applied statistic test do not found significatives differences.Con el objetivo de demostrar la prevalencia de Helicobacter pylori (Hp) en estudiantes de Odontología y establecer la relación de los seroreactores positivos con sintomatologías conexas a Hp como: estrés, gastritis, úlcera y cáncer; se seleccionó al azar una muestra poblacional de 91 estudiantes de 15-24 años de edad, para la detección de anticuerpos IgG en sueros mediante el Kit Platelia Ò A la misma muestra poblacional se le aplicó una ficha para el llenado de sus datos personales y los relacionados con antecedentes familiares, sobre las sintomatologías descritas anteriormente. De un total de 91 estudiantes que completaron el estudio, se encontró una seraprevalencia general del Hp en un 72,5 % (66/91), con prevalencia sexual de 68,3 y 76 %, en mujeres y hombres, respectivamente. Al relacionar los datos declarados en las fichas, con los seroreactores positivos, se halló que: 73,1 % (19/26) sufren estrés, 61,5 % (8/13) sufren gastritis y 100 % (2/2) tienen úlcera. En lo referente a la sintomatologías en el alumno declarados por la muestra estudiantil, se encontró que: el 28,6 % (26/91) sufre de estrés, 14,3 % (13/91) sufre de gastritis y 2,2 % (2191) tiene úlcera. Con relación a las sintomatologías en los familiares declarados por el estudiante, se halló que el 33% (30/91) sufre de gastritis, 18,7 % (17/91) tiene úlcera y 5,5 % (5/91) tiene cáncer. Se concluye que el 72,5 % de los seroreactores positivos, se halla dentro del rango de seroprevalencia de Hp de los países en Desarrollo; que hay una alta relación (&gt; 60 %) de seroreactores positivos con sintomatologías registradas en las fichas como: estrés, gastritis y úlcera; igualmente revelan cifras sugerentes de la presencia de estas sintomatologías tanto en los propios estudiantes, como en relación con sus familiares, sin embargo, las pruebas estadísticas aplicadas no hallaron diferencias significativas

Pembrolizumab as Consolidation Strategy in Patients with Multiple Myeloma: Results of the GEM-Pembresid Clinical Trial

PD1 expression in CD4+ and CD8+ T cells is increased after treatment in multiple myeloma patients with persistent disease. The GEM-Pembresid trial analyzed the efficacy and safety of pembrolizumab as consolidation in patients achieving at least very good partial response but with persistent measurable disease after first- or second-line treatment. Moreover, the characteristics of the immune system were investigated to identify potential biomarkers of response to pembrolizumab. One out of the 17 evaluable patients showed a decrease in the amount of M-protein, although a potential late effect of high-dose melphalan could not be ruled out. Fourteen adverse events were considered related to pembrolizumab, two of which (G3 diarrhea and G2 pneumonitis) prompted treatment discontinuation and all resolving without sequelae. Interestingly, pembrolizumab induced a decrease in the percentage of NK cells at cycle 3, due to the reduction of the circulating and adaptive subsets (0.615 vs. 0.43, p = 0.007; 1.12 vs. 0.86, p = 0.02). In the early progressors, a significantly lower expression of PD1 in CD8+ effector memory T cells (MFI 1327 vs. 926, p = 0.03) was observed. In conclusion, pembrolizumab used as consolidation monotherapy shows an acceptable toxicity profile but did not improve responses in this MM patient population. The trial was registered at clinicaltrials.gov with identifier NCT02636010 and with EUDRACT number 2015-003359-23.This study was funded by Fundación Ramón Areces (FRA 16/003). T.P. is supported by a grant from the AECC (INVES18043PAIN). This study received financial support from Merck Sharp & Dohme of Spain, a subsidiary of Merck & Co., Inc., Whitehouse Station, New Jersey, USA

Nanoinformatics: developing new computing applications for nanomedicine

Nanoinformatics has recently emerged to address the need of computing applications at the nano level. In this regard, the authors have participated in various initiatives to identify its concepts, foundations and challenges. While nanomaterials open up the possibility for developing new devices in many industrial and scientific areas, they also offer breakthrough perspectives for the prevention, diagnosis and treatment of diseases. In this paper, we analyze the different aspects of nanoinformatics and suggest five research topics to help catalyze new research and development in the area, particularly focused on nanomedicine. We also encompass the use of informatics to further the biological and clinical applications of basic research in nanoscience and nanotechnology, and the related concept of an extended ?nanotype? to coalesce information related to nanoparticles. We suggest how nanoinformatics could accelerate developments in nanomedicine, similarly to what happened with the Human Genome and other -omics projects, on issues like exchanging modeling and simulation methods and tools, linking toxicity information to clinical and personal databases or developing new approaches for scientific ontologies, among many others