Two new Pentaphylacaceae species from southern Central America

© 2016, The New York Botanical Garden. We describe two new species of Pentaphylacaceae: Freziera monteverdensis from Costa Rica and Ternstroemia liesneriana from Panama. Line drawings, color images of living plants for one of the species, and discussions comparing the new species to their presumed closest relatives are provided

Seguimiento de las colonias reproductoras de paíño europeo (Hydrobates pelagicus melitensis) en la isla de Benidorm (ZEPA E-121) P.N. Serra Gelada

Informe de actividades y resultados obtenidos en 2021.Este trabajo ha sido posible gracias a la financiación obtenida por varios proyectos: - Ayudas Ramón y Cajal a Ana Sanz Aguilar y Raül Ramos, financiadas por el Ministerio de Innovación y Universidades, la Agencia Estatal de Investigación y el Fondo Social Europeo (RYC-2017- 22796/ RYC-2017- 22055). Fundación Balearia nos facilitó los desplazamientos entre Baleares y la península.Peer reviewe

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

VIII Encuentro de Docentes e Investigadores en Historia del Diseño, la Arquitectura y la Ciudad

Acta de congresoLa conmemoración de los cien años de la Reforma Universitaria de 1918 se presentó como una ocasión propicia para debatir el rol de la historia, la teoría y la crítica en la formación y en la práctica profesional de diseñadores, arquitectos y urbanistas. En ese marco el VIII Encuentro de Docentes e Investigadores en Historia del Diseño, la Arquitectura y la Ciudad constituyó un espacio de intercambio y reflexión cuya realización ha sido posible gracias a la colaboración entre Facultades de Arquitectura, Urbanismo y Diseño de la Universidad Nacional y la Facultad de Arquitectura de la Universidad Católica de Córdoba, contando además con la activa participación de mayoría de las Facultades, Centros e Institutos de Historia de la Arquitectura del país y la región. Orientado en su convocatoria tanto a docentes como a estudiantes de Arquitectura y Diseño Industrial de todos los niveles de la FAUD-UNC promovió el debate de ideas a partir de experiencias concretas en instancias tales como mesas temáticas de carácter interdisciplinario, que adoptaron la modalidad de presentación de ponencias, entre otras actividades. En el ámbito de VIII Encuentro, desarrollado en la sede Ciudad Universitaria de Córdoba, se desplegaron numerosas posiciones sobre la enseñanza, la investigación y la formación en historia, teoría y crítica del diseño, la arquitectura y la ciudad; sumándose el aporte realizado a través de sus respectivas conferencias de Ana Clarisa Agüero, Bibiana Cicutti, Fernando Aliata y Alberto Petrina. El conjunto de ponencias que se publican en este Repositorio de la UNC son el resultado de dos intensas jornadas de exposiciones, cuyos contenidos han posibilitado actualizar viejos dilemas y promover nuevos debates. El evento recibió el apoyo de las autoridades de la FAUD-UNC, en especial de la Secretaría de Investigación y de la Biblioteca de nuestra casa, como así también de la Facultad de Arquitectura de la UCC; va para todos ellos un especial agradecimiento

Evaluation of appendicitis risk prediction models in adults with suspected appendicitis

Background Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis). Results Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent). Conclusion Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified

Two new species of Siphocampylus (Campanulaceae, Lobelioideae) from the Central Andes

Two species of Siphocampylus (Campanulaceae: Lobelioideae) from the Central Andes of Peru and Bolivia are described, illustrated, and discussed with reference to related species. One species, Siphocampylus antonellii, is endemic to high elevation grasslands of Calca, Peru, while the second, S. siberiensis, is endemic to cloud forests of Cochabamba, Bolivia. Both species are robust shrubs that produce tubular pink flowers that are likely pollinated by hummingbirds

Compendium of Freziera (Pentaphylacaceae) of South America including eleven new species and the typification of 22 names

As part of a revision of neotropical Freziera (Pentaphylacaceae) we provide a compendium of the 63 species we recognise for South America including the description, illustration and extinction threat assessment of 11 new species, typification of 22 names and a new combination for Freziera rufescens (Kobuski) D. Santam. & A. K. Monro based on F. canescens forma rufescens. The new species described are Freziera alata A. L. Weitzman ex D. Santam. & A. K. Monro; F. croatii D. Santam. & A. K. Monro; F. ecuadoriensis D. Santam. & A. K. Monro; F. golondrinensis D. Santam. & A. K. Monro; F. monteagudoi D. Santam. & A. K. Monro; F. neei D. Santam. & A. K. Monro; F. peruana D. Santam. & A. K. Monro; F. risaraldana D. Santam. & A. K. Monro; F. siraensis D. Santam. & A. K. Monro; F. trollii D. Santam. & A. K. Monro and F. uniauriculata A. L. Weitzman ex D. Santam. & A. K. Monro. Nine species were assessed as Vulnerable to extinction and two species were assessed as Endangered with extinction. We propose lectotypifications for Eurya inaequalifolia Lingelsh., Freziera arbutifolia Planch. & Triana., F. boliviensis Wawra, F. calophylla Triana & Planch., F. candicans Tul., F. canescens Bonpl., F. chrysophylla Bonpl., F. ferruginea Wawra, F. grisebachii Krug & Urb., F. hieronymi Kobuski, F. lanata (Ruiz & Pav.) Tul., F macrophylla Tul., F. microphylla Sandwith, F. monzonensis (Melch.) Kobuski, F. nervosa Bonpl., F. reticulata Bonpl., F. sericea Bonpl., F. spathulifolia (Melch.) Kobuski, F. suberosa Tul., F. tomentosa (Ruiz & Pav.) Tul., F. wawrai Urb. and F. yungasia Tul

Lectotypification of Peruvian Campanulaceae Names Associated with Collections Made by Augusto Weberbauer

© President and Fellows of Harvard College, 2015. We designate lectotypes for thirteen Peruvian Centropogon and Siphocampylus (Campanulaceae: Lobelioideae) names associated with type collections made by Augusto Weberbauer