Ideación suicida en adolescentes: Una revisión sistemática

La presente investigación tuvo como objetivo determinar los factores relacionados a la ideación suicida en adolescentes. Para esto, se utilizó una muestra de 20 artículos de revisiones sistemáticas con la particularidad de mantener relación con la ideación suicida, en específico, identificar los niveles de incidencia producto de la ideación suicida según genero e identificar los factores protectores. En cuanto a la metodología, se usó tipo de investigación teórica con un diseño de revisión sistemática por sus características de integración de información para realizar una síntesis de la misma. Como resultados, se evidencio un predominio de ideación suicida entre las mujeres sobre los hombres producto de los factores asociados tales como la depresión, el ánimo negativo y la violencia. En cuanto a los factores protectores se demostró que la autoestima alta, el contacto social familiar y los vínculos afectivo activos cumplen la función de revitalizadores en contra de la ideación suicida

Plasmodium falciparum serine repeat protein, a new target of monocyte-dependent antibody-mediated parasite killing

Copyright © American Society for Microbiology, Infection and Immunity, 70(12), 2002, 7182-7184, https://doi.org/10.1128/IAI.70.12.7182-7184.2002.Using monoclonal antibodies and human affinity-purified antibodies specific to the Plasmodium falciparum 126-kDa serine-rich protein, SERP, we found that these antibodies have no direct effect upon merozoite invasion at the concentrations tested but can cooperate with blood monocytes to strongly inhibit P. falciparum in vitro growth

Livestock abundance predicts vampire bat demography, immune profiles, and bacterial infection risk

Human activities create novel food resources that can alter wildlife–pathogen interactions. If resources amplify or dampen, pathogen transmission probably depends on both host ecology and pathogen biology, but studies that measure responses to provisioning across both scales are rare. We tested these relationships with a 4-year study of 369 common vampire bats across 10 sites in Peru and Belize that differ in the abundance of livestock, an important anthropogenic food source. We quantified innate and adaptive immunity from bats and assessed infection with two common bacteria. We predicted that abundant livestock could reduce starvation and foraging effort, allowing for greater investments in immunity. Bats from high-livestock sites had higher microbicidal activity and proportions of neutrophils but lower immunoglobulin G and proportions of lymphocytes, suggesting more investment in innate relative to adaptive immunity and either greater chronic stress or pathogen exposure. This relationship was most pronounced in reproductive bats, which were also more common in high-livestock sites, suggesting feedbacks between demographic correlates of provisioning and immunity. Infection with both Bartonella and haemoplasmas were correlated with similar immune profiles, and both pathogens tended to be less prevalent in high-livestock sites, although effects were weaker for haemoplasmas. These differing responses to provisioning might therefore reflect distinct transmission processes. Predicting how provisioning alters host–pathogen interactions requires considering how both within-host processes and transmission modes respond to resource shifts

The Origins of [CII] Emission in Local Star-forming Galaxies

The [CII] 158um fine-structure line is the brightest emission line observed in local star-forming galaxies. As a major coolant of the gas-phase interstellar medium, [CII] balances the heating, including that due to far-ultraviolet photons, which heat the gas via the photoelectric effect. However, the origin of [CII] emission remains unclear, because C+ can be found in multiple phases of the interstellar medium. Here we measure the fractions of [CII] emission originating in the ionized and neutral gas phases of a sample of nearby galaxies. We use the [NII] 205um fine-structure line to trace the ionized medium, thereby eliminating the strong density dependence that exists in the ratio of [CII]/[NII] 122um. Using the FIR [CII] and [NII] emission detected by the KINGFISH and Beyond the Peak Herschel programs, we show that 60-80% of [CII] emission originates from neutral gas. We find that the fraction of [CII] originating in the neutral medium has a weak dependence on dust temperature and the surface density of star formation, and a stronger dependence on the gas-phase metallicity. In metal-rich environments, the relatively cooler ionized gas makes substantially larger contributions to total [CII] emission than at low abundance, contrary to prior expectations. Approximate calibrations of this metallicity trend are provided.Comment: 8 pages, accepted for publication in Ap

PROCEDIMIENTO: PROTOCOLO DE HYS INGRESO, ESTADIA Y EGRESO EN CONTEXTO DE PANDEMIA COVID 19 - REV. 4

En el marco de la declaración de la emergencia pública en materia sanitaria ante la presencia de la pandemia por COVID-19, y teniendo en cuenta las resoluciones regulatorias en el ámbito laboral, dictadas por el Ministerio de Trabajo de la Nación, Ministerio de Desarrollo Social y Deporte de la provincia de Mendoza y por la Superintendencia de Riesgo del Trabajo, el objeto de este Protocolo de Seguridad e Higiene, es prevenir, proteger y preservar la salud del personal que ingrese a todas las Sedes, CUM, CDD de la Universidad, en consonancia con las recomendaciones de las carteras laborales nacionales y provinciales, y de la Organización Mundial de la Salud. REV.

A multicentre case-control study of nonsteroidal anti-inflammatory drugs as a risk factor for severe sepsis and septic shock

International audienceINTRODUCTION: We aimed to establish whether the use of nonsteroidal anti-inflammatory drugs (NSAIDs) during evolving bacterial community-acquired infection in adults is associated with severe sepsis or septic shock. METHODS: We conducted a multicentre case-control study in eight intensive care units. Cases were all adult patients admitted for severe sepsis or septic shock due to a bacterial community-acquired infection. Control individuals were patients hospitalized with a mild community-acquired infection. Each case was matched to one control for age, presence of diabetes and site of infection. RESULTS: The main outcome measures were the proportions of cases and controls exposed to NSAIDs or aspirin during the period of observation. In all, 152 matched pairs were analyzed. The use of NSAIDs or aspirin during the observation period did not differ between cases and controls (27% versus 28; odds ratio = 0.93, 95% confidence interval [CI] = 0.52 to 1.64). If aspirin was not considered or if a distinction was made between acute and chronic drug treatment, there remained no difference between groups. However, the median time to prescription of effective antibiotic therapy was longer for NSAID users (6 days, 95% CI = 3 to 7 days) than for nonusers (3 days, 95% CI = 2 to 3 days; P = 0.02). CONCLUSIONS: In this study, the use of NSAIDs or aspirin during evolving bacterial infection was frequent and occurred in one-quarter of the patients with such infection. Although the use of NSAIDs by patients with severe sepsis or septic shock did not differ from their use by those with mild infection at the same infected site, we observed a longer median time to prescription of effective antibiotic therapy in NSAID users