1,084 research outputs found
Health Reform in Massachusetts as of Fall 2010: Getting Ready for the Affordable Care Act & Addressing Affordability
Provides updated survey findings about trends since fall 2006 in the insurance coverage, healthcare access and use, costs and affordability, financial difficulties, and attitudes toward state healthcare reform among non-elderly adults in Massachusetts
Lensing magnification of supernovae in the GOODS-fields
Gravitational lensing of high-redshift supernovae is potentially an important
source of uncertainty when deriving cosmological parameters from the measured
brightness of Type Ia supernovae, especially in deep surveys with scarce
statistics. Photometric and spectroscopic measurements of foreground galaxies
along the lines-of-sight of 33 supernovae discovered with the Hubble Space
Telescope, both core-collapse and Type Ia, are used to model the magnification
probability distributions of the sources. Modelling galaxy halos with SIS or
NFW-profiles and using M/L scaling laws provided by the Faber-Jackson and
Tully-Fisher relations, we find clear evidence for supernovae with lensing
(de)magnification. However, the magnification distribution of the Type Ia
supernovae used to determine cosmological distances matches very well the
expectations for an unbiased sample, i.e.their mean magnification factor is
consistent with unity. Our results show that the lensing distortions of the
supernova brightness can be well understood for the GOODS sample and that
correcting for this effect has a negligible impact on the derived cosmological
parameters.Comment: 22 pages, 9 figures, accepted for publication by Ap
Complementary therapies for labour and birth: A randomized controlled trial of antenatal integrative medicine for pain management in labour
Objective: To evaluate the effect of an antenatal integrative medicine education programme in addition to usual care for nulliparous women on intrapartum epidural use.
Design: Open-label, assessor blind, randomized controlled trial.
Setting: 2 public hospitals in Sydney, Australia.
Population: 176 nulliparous women with low-risk pregnancies, attending hospital-based antenatal clinics.
Methods and intervention: The Complementary Therapies for Labour and Birth protocol, based on the She Births and acupressure for labour and birth courses, incorporated 6 evidence-based complementary medicine techniques: acupressure, visualisation and relaxation, breathing, massage, yoga techniques, and facilitated partner support. Randomisation occurred at 24–36 weeks’ gestation, and participants attended a 2-day antenatal education programme plus standard care, or standard care alone.
Main outcome measures: Rate of analgesic epidural use. Secondary: onset of labour, augmentation, mode of birth, newborn outcomes.
Results:There was a significant difference in epidural use between the 2 groups: study group (23.9%) standard care (68.7%; risk ratio (RR) 0.37 (95% CI 0.25 to 0.55), p≤0.001). The study group participants reported a reduced rate of augmentation (RR=0.54 (95% CI 0.38 to 0.77), p
Conclusions: The Complementary Therapies for Labour and Birth study protocol significantly reduced epidural use and caesarean section. This study provides evidence for integrative medicine as an effective adjunct to antenatal education, and contributes to the body of best practice evidence
Relaxation techniques for pain management in labour
Background: Many women would like to avoid pharmacological or invasive methods of pain management in labour and this may contribute to the popularity of complementary methods of pain management. This review examined currently available evidence on the use of relaxation therapies for pain management in labour. This is an update of a review first published in 2011.
Objectives: To examine the effects of mind-body relaxation techniques for pain management in labour on maternal and neonatal well-being during and after labour.
Search methods: We searched Cochrane Pregnancy and Childbirth’s Trials Register (9 May 2017), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, Issue 5 2017), MEDLINE (1966 to 24 May 2017), CINAHL (1980 to 24 May 2017), the Australian New Zealand Clinical Trials Registry (18 May 2017), ClinicalTrials.gov (18 May 2017), the ISRCTN Register (18 May 2017), the WHO International Clinical Trials Registry Platform (ICTRP) (18 May 2017), and reference lists of retrieved studies.
Selection criteria: Randomised controlled trials (including quasi randomised and cluster trials) comparing relaxation methods with standard care, no treatment, other non-pharmacological forms of pain management in labour or placebo.
Data collection and analysis: Two review authors independently assessed trials for inclusion and risk of bias, extracted data and checked them for accuracy. We attempted to contact study authors for additional information. We assessed evidence quality with GRADE methodology.
Main results: This review update includes 19 studies (2519 women), 15 of which (1731 women) contribute data. Interventions examined included relaxation, yoga, music and mindfulness. Approximately half of the studies had a low risk of bias for random sequence generation and attrition bias. The majority of studies had a high risk of bias for performance and detection bias, and unclear risk of bias for, allocation concealment, reporting bias and other bias. We assessed the evidence from these studies as ranging from low to very low quality, and therefore the effects below should be interpreted with caution
Blunt cones in rarefied hypersonic flow: Experiments and Monte-Carlo simulations
The drag coefficients for cones with hot and cold walls and different bluntness ratios have been found experimentally. There is a small wall temperature effect which can be accounted for by the change in the pressure drag that occurs in the free molecular limiting flow. The results from the Monte-Carlo calculations agree well with the experiments and they show that the flow field is characterised by the free molecular behaviour at least as far as Knudsen = 0.02 (based on bade diameter) and that the shear drag is the predominant force. From the experimental results it seems reasonable to conclude that the flow fields are characterised by the free molecular behaviour down to the lowest value of Knudsen number tested, which was 0.006. The nose bluntness effect on the measured drag can be correlated by normalising the coefficient by the value in the free molecular limit and by defining a Knudsen number based on the cone lengt
Near-IR Search for Lensed Supernovae Behind Galaxy Clusters - II. First Detection and Future Prospects
Powerful gravitational telescopes in the form of massive galaxy clusters can
be used to enhance the light collecting power over a limited field of view by
about an order of magnitude in flux. This effect is exploited here to increase
the depth of a survey for lensed supernovae at near-IR wavelengths. A pilot SN
search program conducted with the ISAAC camera at VLT is presented. Lensed
galaxies behind the massive clusters A1689, A1835 and AC114 were observed for a
total of 20 hours split into 2, 3 and 4 epochs respectively, separated by
approximately one month to a limiting magnitude J<24 (Vega). Image subtractions
including another 20 hours worth of archival ISAAC/VLT data were used to search
for transients with lightcurve properties consistent with redshifted
supernovae, both in the new and reference data. The feasibility of finding
lensed supernovae in our survey was investigated using synthetic lightcurves of
supernovae and several models of the volumetric Type Ia and core-collapse
supernova rates as a function of redshift. We also estimate the number of
supernova discoveries expected from the inferred star formation rate in the
observed galaxies. The methods consistently predict a Poisson mean value for
the expected number of SNe in the survey between N_SN=0.8 and 1.6 for all
supernova types, evenly distributed between core collapse and Type Ia SN. One
transient object was found behind A1689, 0.5" from a galaxy with photometric
redshift z_gal=0.6 +- 0.15. The lightcurve and colors of the transient are
consistent with being a reddened Type IIP SN at z_SN=0.59. The lensing model
predicts 1.4 magnitudes of magnification at the location of the transient,
without which this object would not have been detected in the near-IR ground
based search described in this paper (unlensed magnitude J~25). (abridged)Comment: Accepted by AA, matches journal versio
Finite elements and the discrete variable representation in nonequilibrium Green's function calculations. Atomic and molecular models
In this contribution, we discuss the finite-element discrete variable
representation (FE-DVR) of the nonequilibrium Green's function and its
implications on the description of strongly inhomogeneous quantum systems. In
detail, we show that the complementary features of FEs and the DVR allows for a
notably more efficient solution of the two-time Schwinger/Keldysh/Kadanoff-Baym
equations compared to a general basis approach. Particularly, the use of the
FE-DVR leads to an essential speedup in computing the self-energies.
As atomic and molecular examples we consider the He atom and the linear
version of H in one spatial dimension. For these closed-shell models we,
in Hartree-Fock and second Born approximation, compute the ground-state
properties and compare with the exact findings obtained from the solution of
the few-particle time-dependent Schr\"odinger equation.Comment: 12 pages, 3 figures, submitted as proceedings of conference "PNGF IV
Nonequilibrium Green's functions approach to strongly correlated few-electron quantum dots
The effect of electron-electron scattering on the equilibrium properties of
few-electron quantum dots is investigated by means of nonequilibrium Green's
functions theory. The ground and equilibrium state is self-consistently
computed from the Matsubara (imaginary time) Green's function for the spatially
inhomogeneous quantum dot system whose constituent charge carriers are treated
as spin-polarized. To include correlations, the Dyson equation is solved,
starting from a Hartree-Fock reference state, within a conserving (second
order) self-energy approximation where direct and exchange contributions to the
electron-electron interaction are included on the same footing.
We present results for the zero and finite temperature charge carrier
density, the orbital-resolved distribution functions and the self-consistent
total energies and spectral functions for isotropic, two-dimensional parabolic
confinement as well as for the limit of large anisotropy--quasi-one-dimensional
entrapment. For the considered quantum dots with N=2, 3 and 6 electrons, the
analysis comprises the crossover from Fermi gas/liquid (at large carrier
density) to Wigner molecule or crystal behavior (in the low-density limit)
Massage, reflexology and other manual methods for pain management in labour
Background
Many women would like to avoid pharmacological or invasive methods of pain management in labour, and thismay contribute towards the popularity of complementary methods of pain management. This review examined the evidence currently available on manual methods, including massage and reflexology, for pain management in labour. This review is an update of the review first published in 2012.
Objectives
To assess the effect, safety and acceptability of massage, reflexology and other manual methods to manage pain in labour.
Search methods
For this update, we searched Cochrane Pregnancy and Childbirth’s Trials Register (30 June 2017), the Cochrane Central Register of Controlled Trials (CENTRAL; 2017, Issue 6), MEDLINE (1966 to 30 June 2017, CINAHL (1980 to 30 June 2017), the Australian New Zealand Clinical Trials Registry (4 August 2017), Chinese Clinical Trial Registry (4 August 2017), ClinicalTrials.gov, (4 August 2017), the National Center for Complementary and Integrative Health (4 August 2017), theWHO International Clinical Trials Registry Platform (ICTRP) (4 August 2017) and reference lists of retrieved trials.
Selection criteria
We included randomised controlled trials comparing manual methods with standard care, other non pharmacological forms of pain management in labour, no treatment or placebo. We searched for trials of the following modalities: massage, warm packs, thermal manual methods, reflexology, chiropractic, osteopathy, musculo-skeletal manipulation, deep tissue massage, neuro-muscular therapy, shiatsu, tuina, trigger point therapy, myotherapy and zero balancing. We excluded trials for pain management relating to hypnosis, aromatherapy, acupuncture and acupressure; these are included in other Cochrane reviews.
Data collection and analysis
Two review authors independently assessed trial quality, extracted data and checked data for accuracy. We contacted trial authors for additional information. We assessed the quality of the evidence using the GRADE approach.
Main results
We included a total of 14 trials; 10 of these (1055 women) contributed data to meta-analysis. Four trials, involving 274 women, metour inclusion criteria but did not contribute data to the review. Over half the trials had a low risk of bias for random sequence generationand attrition bias. The majority of trials had a high risk of performance bias and detection bias, and an unclear risk of reporting bias.We found no trials examining the effectiveness of reflexology.
Massage
We found low-quality evidence that massage provided a greater reduction in pain intensity (measured using self-reported pain scales) than usual care during the first stage of labour (standardised mean difference (SMD) −0.81, 95% confidence interval (CI) −1.06 to −0.56, six trials, 362 women). Two trials reported on pain intensity during the second and third stages of labour, and there was evidence of a reduction in pain scores in favour of massage (SMD −0.98, 95% CI −2.23 to 0.26, 124 women; and SMD −1.03, 95% CI −2.17 to 0.11, 122 women). There was very low-quality evidence showing no clear benefit of massage over usual care for the length of labour (in minutes) (mean difference (MD) 20.64, 95% CI −58.24 to 99.52, six trials, 514 women), and pharmacological pain relief (average risk ratio (RR) 0.81, 95% CI 0.37 to 1.74, four trials, 105 women). There was very low-quality evidence showing no clear benefit of massage for assisted vaginal birth (average RR 0.71, 95% CI 0.44 to 1.13, four trials, 368 women) and caesarean section (RR 0.75, 95% CI 0.51 to 1.09, six trials, 514 women). One trial reported less anxiety during the first stage of labour for women receiving massage (MD -16.27, 95% CI −27.03 to −5.51, 60 women). One trial found an increased sense of control from massage (MD 14.05, 95% CI 3.77 to 24.33, 124 women, low-quality evidence). Two trials examining satisfaction with the childbirth experience reported data on different scales; both found more satisfaction with massage, although the evidence was low quality in one study and very low in the other.
Warm packs
We found very low-quality evidence for reduced pain (Visual Analogue Scale/VAS) in the first stage of labour (SMD −0.59, 95%CI −1.18 to −0.00, three trials, 191 women), and the second stage of labour (SMD −1.49, 95% CI −2.85 to −0.13, two trials,128 women). Very low-quality evidence showed reduced length of labour (minutes) in the warm-pack group (MD −66.15, 95% CI −91.83 to −40.47; two trials; 128 women).
Thermal manual methods
One trial evaluated thermal manual methods versus usual care and found very low-quality evidence of reduced pain intensity during The first phase of labour for women receiving thermal methods (MD −1.44, 95% CI −2.24 to −0.65, one trial, 96 women). There was a reduction in the length of labour (minutes) (MD −78.24, 95% CI −118.75 to −37.73, one trial, 96 women, very low-quality evidence). There was no clear difference for assisted vaginal birth (very low-quality evidence). Results were similar for cold packs versus usual care, and intermittent hot and cold packs versus usual care, for pain intensity, length of labour and assisted vaginal birth.
Music
One trial that compared manual methods with music found very low-quality evidence of reduced pain intensity during labour in the massage group (RR 0.40, 95% CI 0.18 to 0.89, 101 women). There was no evidence of benefit for reduced use of pharmacological pain relief (RR 0.41, 95% CI 0.16 to 1.08, very low-quality evidence). Of the seven outcomes we assessed using GRADE, only pain intensity was reported in all comparisons. Satisfaction with the childbirthexperience, sense of control, and caesarean section were rarely reported in any of the comparisons.
Authors’ conclusions
Massage, warm pack and thermal manual methods may have a role in reducing pain, reducing length of labour and improving women’s sense of control and emotional experience of labour, although the quality of evidence varies from low to very low and few trials reported on the keyGRADE outcomes. Few trials reported on safety as an outcome. There is a need for further research to address these outcomes and to examine the effectiveness and efficacy of these manual methods for pain management
Gastro-oesophageal reflux: A mixed methods study of infants admitted to hospital in the first 12months following birth in NSW (2000-2011)
© 2018 The Author(s). Background: Gastro-oesophageal reflux (GOR) is common in infants. When the condition causes pathological symptoms and/or complications it is considered gastro-oesophageal reflux disease (GORD). It appears to be increasingly diagnosed and causes great distress in the first year of infancy. In New South Wales (NSW), residential parenting services support families with early parenting difficulties. These services report a large number of babies admitted with a label of GOR/GORD. The aim of this study was to explore the maternal and infant characteristics, obstetric interventions, and reasons for clinical reporting of GOR/GORD in NSW in the first 12months following birth (2000-2011). Methods: A three phase, mixed method sequential design was used. Phase 1 included a linked data population based study (n=869,188 admitted babies). Phase 2 included a random audit of 326 medical records from admissions to residential parenting centres in NSW (2013). Phase 3 included eight focus groups undertaken with 45 nurses and doctors working in residential parenting centres in NSW. Results: There were a total of 1,156,020 admissions recorded of babies in the first year following birth, with 11,513 containing a diagnostic code for GOR/GORD (1% of infants admitted to hospitals in the first 12months following birth). Babies with GOR/GORD were also more likely to be admitted with other disorders such as feeding difficulties, sleep problems, and excessive crying. The mothers of babies admitted with a diagnostic code of GOR/GORD were more likely to be primiparous, Australian born, give birth in a private hospital and have: a psychiatric condition; a preterm or early term infant (37-or-38weeks); a caesarean section; an admission of the baby to SCN/NICU; and a male infant. Thirty six percent of infants admitted to residential parenting centres in NSW had been given a diagnosis of GOR/GORD. Focus group data revealed two themes: "It is over diagnosed" and "A medical label is a quick fix, but what else could be going on?" Conclusions: Mothers with a mental health disorder are nearly five times as likely to have a baby admitted with GOR/GORD in the first year after birth. We propose a new way of approaching the GOR/GORD issue that considers the impact of early birth (immaturity), disturbance of the microbiome (caesarean section) and mental health (maternal anxiety in particular)
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