87 research outputs found

    Reach Extension and Capacity Enhancement of VCSEL-Based Transmission Over Single-Lane MMF Links

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    This paper reviews and examines several techniques for expanding the carrying capacity of multimode fiber (MMF) using vertical cavity surface emitting lasers (VCSELs). The first approach utilizes short wavelength division multiplexing in combination with MMF optimized for operation between 850 and 950 nm. Both nonreturn to zero (NRZ) and four-level pulse amplitude modulation (PAM4) signaling are measured and demonstrate up to 170-Gb/s postforward error correction transmission over 300 m. For single wavelength transmission, the use of selective modal launch to increase the optical bandwidth of a standard OM3 MMF to more than 2.1 GHzkm for standard MMF is presented. A statistical model is used to predict the bandwidth enhancement of installed MMF and indicates that significant link extension can be achieved using selective modal launch techniques. These results demonstrate the continued effectiveness of VCSEL-based MMF links in current and future data center environments

    Production of Y(1S) Mesons from chib Decays in pp(bar) Collisions at sqrt(s)=1.8 TeV

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    We have reconstructed the radiative decays χb(1P)Υ(1S)γ\chi_{b}(1P) \to \Upsilon(1S) \gamma and χb(2P)Υ(1S)γ\chi_{b}(2P) \to \Upsilon(1S) \gamma in ppˉp \bar{p} collisions at s=1.8\sqrt{s} = 1.8 TeV, and measured the fraction of Υ(1S)\Upsilon(1S) mesons that originate from these decays. For Υ(1S)\Upsilon(1S) mesons with pTΥ>8.0p^{\Upsilon}_{T}>8.0 GeV/cc, the fractions that come from χb(1P)\chi_{b}(1P) and χb(2P)\chi_{b}(2P) decays are (27.1±6.9(stat)±4.4(sys))(27.1\pm6.9(stat)\pm4.4(sys))% and (10.5±4.4(stat)±1.4(sys))(10.5\pm4.4(stat)\pm1.4(sys))%, respectively. We have derived the fraction of directly produced Υ(1S)\Upsilon(1S) mesons to be (50.9±8.2(stat)±9.0(sys))(50.9\pm8.2(stat)\pm9.0(sys))%.Comment: 13 Pages, 2 figure

    Monoclonal antibody ONS-M21 recognizes integrin α3 in gliomas and medulloblastomas

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    The monoclonal antibody ONS-M21 recognizes an antigen found on the surface of glioma and medulloblastoma cells but does not react with the antigens of normal brain tissue. We purified and identified the 140-kDa protein by means of an antibody-binding affinity column. This 140-kDa antigen has sequences homologous to the amino-terminal region and five parts of the internal domain of integrin α3. When the integrin α3-related sequences was amplified and used to analyse the mRNA of glioma and medulloblastoma surgical specimens, the transcription level of integrin α3 mRNA appeared to be quantitatively correlated with the grade of malignancy. These findings suggest that the ONS-M21 antibody, which reacts with integrin α3, might be useful in the diagnosis of gliomas and medulloblastomas. © 1999 Cancer Research Campaig

    Phenomenology of Heavy Meson Chiral Lagrangians

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    The approximate symmetries of Quantum ChromoDynamics in the infinite heavy quark (Q=c,bQ=c,b) mass limit (mQm_Q \to \infty) and in the chiral limit for the light quarks (mq0,  q=u,d,sm_q \to 0,\;q=\,u,\,d,\,s) can be used together to build up an effective chiral lagrangian for heavy and light mesons describing strong interactions among effective meson fields as well as their couplings to electromagnetic and weak currents, including the relevant symmetry breaking terms. The effective theory includes heavy (QqˉQ \bar q) mesons of both negative and positive parity, light pseudoscalars, as well as light vector mesons. We summarize the estimates for the parameters entering the effective lagrangian and discuss in particular some phenomenologically important couplings, such as gBBπg_{B^* B \pi}. The hyperfine splitting of heavy mesons is discussed in detail. The effective lagrangian allows for the possibility to describe consistently weak couplings of heavy (B,DB,\, D) to light (π,ρ,K,\pi,\, \rho, \, K^*,\, etc.) mesons. The method has however its own limitations, due to the requirement that the light meson momenta should be small, and we discuss how such limitations can be circumvented through reasonable ansatz on the form factors. Flavour conserving (e. g. BBγB^* \to B\, \gamma) and flavour changing (e. g. BKγB \to K^* \, \gamma) radiative decays provide another field of applications of effective lagrangians; they are discussed together with their phenomenological implications. Finally we analyze effective lagrangians describing heavy charmonium- like (QˉQ\bar Q Q) mesons and their strong and electromagnetic interactions. The role of approximate heavy quark symmetries for this case and the phenomenological tests of these models are also discussed.Comment: 92 pages, LaTeX, 17 figures, to appear in Physics Reports, page size shortened to fit american forma

    A comprehensive overview of radioguided surgery using gamma detection probe technology

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    The concept of radioguided surgery, which was first developed some 60 years ago, involves the use of a radiation detection probe system for the intraoperative detection of radionuclides. The use of gamma detection probe technology in radioguided surgery has tremendously expanded and has evolved into what is now considered an established discipline within the practice of surgery, revolutionizing the surgical management of many malignancies, including breast cancer, melanoma, and colorectal cancer, as well as the surgical management of parathyroid disease. The impact of radioguided surgery on the surgical management of cancer patients includes providing vital and real-time information to the surgeon regarding the location and extent of disease, as well as regarding the assessment of surgical resection margins. Additionally, it has allowed the surgeon to minimize the surgical invasiveness of many diagnostic and therapeutic procedures, while still maintaining maximum benefit to the cancer patient. In the current review, we have attempted to comprehensively evaluate the history, technical aspects, and clinical applications of radioguided surgery using gamma detection probe technology
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