Wireless Content Caching for Small Cell and D2D Networks

The fifth generation wireless networks must provide fast and reliable connectivity while coping with the ongoing traffic growth. It is of paramount importance that the required resources, such as energy and bandwidth, do not scale with traffic. While the aggregate network traffic is growing at an unprecedented rate, users tend to request the same popular contents at different time instants. Therefore, caching the most popular contents at the network edge is a promising solution to reduce the traffic and the energy consumption over the backhaul links. In this paper, two scenarios are considered, where caching is performed either at a small base station, or directly at the user terminals, which communicate using Device-to-Device (D2D) communications. In both scenarios, joint design of the transmission and caching policies is studied when the user demands are known in advance. This joint design offers two different caching gains, namely, the pre-downloading and local caching gains. It is shown that the finite cache capacity limits the attainable gains, and creates an inherent tradeoff between the two types of gains. In this context, a continuous time optimization problem is formulated to determine the optimal transmission and caching policies that minimize a generic cost function, such as energy, bandwidth, or throughput. The jointly optimal solution is obtained by demonstrating that caching files at a constant rate is optimal, which allows reformulation of the problem as a finite-dimensional convex program. The numerical results show that the proposed joint transmission and caching policy dramatically reduces the total cost, which is particularised to the total energy consumption at the Macro Base Station (MBS), as well as to the total economical cost for the service provider, when users demand economical incentives for delivering content to other users over the D2D links

Homecare physiotherapy in the iberian peninsula public health system

Objetivos - Conocer los principales servicios de fisioterapia domiciliaria que oferta el Sistema Sanitario Público para las personas mayores dependientes de la Península Ibérica (España y Portugal). Estrategia de búsqueda - Revisión bibliográfica actualizada y exhaustiva sobre los estudios previos; estancia de investigación en Hospitales, Centros de Salud y organismos financiados por la Administración Pública en ambos países; entrevistas en profundidad a informantes estratégicos. Síntesis de los resultados - Se describe la situación de la fisioterapia domiciliaria en España, desde el año 1987 hasta agosto de 2008. Se detecta que en Portugal la fisioterapia domiciliaria está recogida en la cartera de servicios de atención primaria (Decreto-Ley no 28/2008, del 22 de febrero). Conclusiones - Existen pocas investigaciones a nivel de la Península que ofrezcan datos objetivos basados en la evidencia científica sobre la efectividad de estos servicios de fisioterapia, la satisfacción del usuario y las repercusiones que producen con respecto a otros tratamientos; sin embargo, estos estudios son necesarios para la evaluación de las políticas sanitarias, la distribución adecuada de recursos, la revisión de los programas, la metodología de actuación, etc.ABSTRACT - Objectives: To become acquainted with the principal homecare physiotherapy services that are offered by the Public Health System for dependent elderly patients in the Iberian Peninsula (Spain and Portugal). Methods: A thorough and updated review of the literature regarding previous studies, research stays in Hospitals, Primary Health Care Centers and Public Health institutions in both countries financed by the Public Health Administration; in-depth interviews with specific informants. Results: The situation of homecare physiotherapy in Spain from the year 1987 to the August 2008 is described. In Portugal, these services are established within the services regulated by Primary Health Care (Decree-Law no. 28/2008, of February 22). Conclusions: There are few studies in the Iberian Peninsula that offer scientific evidence-based information on the effectiveness of these physiotherapy services, user satisfaction and the effect they have in relation to other treatments. However, these studies are needed in order to evaluate the current health legislation, appropriate distribution of resources, to review the clinical programs, clinical action methodologies, etc.info:eu-repo/semantics/publishedVersio

Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice

Recent evidence indicates that the gut microbiota plays a key role in the pathophysiology of obesity. Indeed, diet-induced obesity (DIO) has been associated to substantial changes in gut microbiota composition in rodent models. In the context of obesity, enhanced adiposity is accompanied by low-grade inflammation of this tissue but the exact link with gut microbial community remains unknown. In this report, we studied the consequences of high-fat diet (HFD) administration on metabolic parameters and gut microbiota composition over different periods of time. We found that Akkermansia muciniphila abundance was strongly and negatively affected by age and HFD feeding and to a lower extend Bilophila wadsworthia was the only taxa following an opposite trend. Different approaches, including multifactorial analysis, showed that these changes in Akkermansia muciniphila were robustly correlated with the expression of lipid metabolism and inflammation markers in adipose tissue, as well as several circulating parameters (i.e., glucose, insulin, triglycerides, leptin) from DIO mice. Thus, our data shows the existence of a link between gut Akkermansia muciniphila abundance and adipose tissue homeostasis on the onset of obesity, thus reinforcing the beneficial role of this bacterium on metabolism

Fate of drugs during wastewater treatment

This is the post-print version of the final paper published in TrAC Trends in Analytical Chemistry. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2013 Elsevier B.V.Recent trends in the determination of pharmaceutical drugs in wastewaters focus on the development of rapid multi-residue methods. This review addresses recent analytical trends in drug determination in environmental matrices used to facilitate fate studies. Analytical requirements for further fate evaluation and tertiary process selection and optimization are also discussed.EPSRC, Northumbrian Water, Anglian Water, Severn Trent Water, Yorkshire Water, and United Utilities

Girder–Deck Interface: Partial Debonding, Deck Replacement, and Composite Action

Results are reported from tests of three precast, prestressed concrete girders under fatigue-type cyclic and monotonic loading conducted after deck removal and replacement. Although deck demolition altered the top surface of the girders, the girder–deck interfaces exhibited shear strengths greater than their nominal strength (based on the 2012 AASHTO LRFD Specification) after 2 × 106 cycles of loading to 45 and 30% of their nominal strength for troweled and roughened interfaces, respectively. A partially debonded detail was used for two of the girders to protect the girder top flange, which was wide and thin, during deck demolition. The roofing felt used to debond the girder–deck interface over the flanges reduced the effort required for deck removal by 65%, compared with the typical detail, eliminated chipping hammer–induced damage to the girder flanges, and still resulted in sustained composite action under 2 × 106 cycles of loading. The width of the bonded interface had little effect on girder stiffness and no observed effect on the width of deck effective in bending

Strut-and-tie model based on crack band theory for deep beams

yesA simplified strut-and-tie model including size effect based on the crack band theory is proposed to evaluate the shear capacity of deep beams. Concrete struts are idealized as uniformly tapered prismatic members with a stress relief strip whereas horizontal and vertical shear reinforcements are assumed to be an internally statically indeterminate system. The shear transfer mechanism of concrete and shear reinforcement is then driven by using the energy equilibrium in the stress relief strip and crack band zone of concrete struts. The shear capacity predictions of deep beams obtained from the present models are in better agreement with 637 test results than those determined from strut-and-tie models proposed by ACI 318-08, EC-2, and Tan and Cheng. In addition, the trend of the shear capacity of deep beams against different parameters as predicted by the present models has a consistent agreement with that observed from experimental results. In particular, the present model shows that the normalized shear capacity of deep beams is proportional to (h)−0.25, where h = section overall depth

First Report of the Mayan Cichlid, Cichlasoma urophthalmus (Günther 1862) Collected in the Southern Littoral Zone of Lake Okeechobee, Florida

Here we report the collection of five juvenile Mayan cichlids in Lake Okeechobee, a large, shallow subtropical lake (26°60\u27N, 80°50\u27W). These specimens were collected on 4 and 10 November 2003 in the southern littoral zone of Lake Okeechobee at a site off the southwest tip of Torry Island (26°42\u27N, 80°44\u27W). The lake stage of this densely vegetated area is highly variable. Nico (in press) reported a single collection of 16 juvenile Mayan cichlids in 2001 from a backwater area in the rim-canal along the NE portion of Lake Okeechobee; an area that is hydrologically isolated from the lake proper, except for several navigation locks and water control structures

Application of Plasticity Theory to Reinforced Concrete Deep Beams

yesThis paper reviews the application of the plasticity theory to reinforced concrete deep beams. Both the truss analogy and mechanism approach were employed to predict the capacity of reinforced concrete deep beams. In addition, most current codes of practice, for example Eurocode 1992 and ACI 318-05, recommend the strut-and-tie model for designing reinforced concrete deep beams. Compared with methods based on empirical or semi-empirical equations, the strut-and-tie model and mechanism analyses are more rational, adequately accurate and sufficiently simple for estimating the load capacity of reinforced concrete deep beams. However, there is a problem of selecting the effectiveness factor of concrete as reflected in the wide range of values reported in the literature for deep beams