75 research outputs found
Environmental Ethics And Sustainable Territorial Development. An Analysis From The Speciesism Category
The article proposes ways to relate discussions held at the field of Environmental Ethics with analysis about the Sustainable Territorial Development. For this, a summary discussion of this field is presented, emphasizing the category of Speciesism and the problem of moral consideration of animals. This approach aims to show the heuristic potential that this category have to analyse patterns of territorial development supported by livestock. From an empirical point of view, the article analyses data from the meat industry in Santa Catarina, from which the notion of Intensive Speciesism Regions (ISR) is outlined. They constitute territories that show Speciesism disproportionately intense in their development patterns, result of a socio-political, economic and symbolic process that combines radical moral disregard of animals with unrighteousness among humans.194395
Riemannian foliations on contractible manifolds
We prove that Riemannian foliations on complete contractible manifolds have a closed leaf, and that all leaves are closed if one closed leaf has a finitely generated fundamental group. Under additional topological or geometric assumptions we prove that the foliation is also simple
Riemannian foliations on contractible manifolds
We prove that Riemannian foliations on complete contractible manifolds have a closed leaf, and that all leaves are closed if one closed leaf has a finitely generated fundamental group. Under additional topological or geometric assumptions we prove that the foliation is also simple
Inequalities in health and community-oriented social work: lessons from Cuba?
Social justice is, as the World Health Organization Commission on Social Determinants of Health (WHO CSDH, 2008) reminds us, ‘a matter of life and death’. While the stark differences in mortality rates and life expectancy between rich and poor countries might be the most obvious example of this, it is also true that ‘Within countries, the differences in life chances are dramatic and are seen in all countries – even the richest’ (WHO CSDH, 2008: 26). As the Commission demonstrates, the roots of these inequities lie in social conditions, suggesting an important role for social work in this area. Unfortunately, the Commission says very little about the type of social work that might be appropriate: nevertheless, the report does provide fresh impetus to the debate about what social workers might contribute to tackling health inequalities. In this article, we suggest that a community-oriented approach to social work is required. In making a case for this, we review the progress of the government’s drive to reduce inequalities in England,1 arguing that this has, thus far, been largely unsuccessful because it has primarily been pursued through health-care services, while addressing the wider (social) determinants of health has been a secondary consideration. In contrast, we offer the example of Cuban community-oriented social work (COSW) which has helped maintain population health at a level that stands comparison with much wealthier nations, despite the hardships and inequalities which followed economic collapse in the 1990s. In many ways the Cuban situation is unusual, perhaps unique, so we are not arguing that Cuban social work methods can be readily transferred. Rather, we suggest that, in the neglected field of tackling health inequalities, social workers can learn from the general approach taken in Cuba. To establish the context of this discussion, we begin by defining key concepts: COSW itself, health inequalities and inequity, the health gap and the health gradient
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
© 2024 The Authors. Journal of Extracellular Vesicles, published by Wiley Periodicals, LLC on behalf of the International Society for Extracellular Vesicles. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY), https://creativecommons.org/licenses/by/4.0/Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its 'Minimal Information for Studies of Extracellular Vesicles', which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly.Peer reviewe
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its 'Minimal Information for Studies of Extracellular Vesicles', which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly
Antecedenti motivazionali, emozioni di riuscita e comprensione di testi multipli online in studenti di scuola primaria
Introduzione. Nel contesto scolastico, le emozioni giocano un ruolo centrale sia per il benessere sia per la buona riuscita degli studenti (Pekrun & Perry, 2014). Nonostante il numero crescente di ricerche su tali temi, solo recentemente si sono studiate le emozioni provate da bambini di scuola primaria, focalizzandosi su discipline quali la matematica o la lingua madre (Lichtenfeld, Pekrun, Stupnisky, Reiss, & Murayama, 2012; Raccanello, Brondino, Mo\ue8, Stupnisky, & Lichtenfeld, 2018). Pochi studi si sono tuttavia occupati della relazione tra emozioni e abilit\ue0 specifiche di comprensione di testi multipli online (Mason, Scrimin, Tornatora, & Zaccoletti, 2017), abilit\ue0 complesse e centrali nel XXI secolo. Lo scopo di questo lavoro \ue8 stato studiare, in riferimento alla lettura, le relazioni tra emozioni e antecedenti motivazionali da un lato, e la comprensione di testi multipli online dall\u2019altro. Metodo. Hanno partecipato 335 studenti del quarto e quinto anno di scuola primaria (et\ue0 media = 10;0; range: 9;1-12;1; 55% F), che hanno compilato misure riguardanti (a) senso di efficacia e valore dato al compito relativi alla lettura (Br\ue5ten, Ferguson, Anmarkrud, & Str\uf8ms\uf8, 2013) in una prima sessione; (b) gioia, noia e ansia relative alla lettura, riferite a tre setting scolastici (lezioni, compiti per casa, verifiche; Achievement Emotions Questionnaire-Elementary School, AEQ-ES, Lichtenfeld et al., 2012) in una seconda sessione; (c) comprensione di testi multipli online (Florit, Cain, & Mason, 2017) in una terza sessione. Risultati. Tramite tre path analysis, separate per emozioni, si \ue8 esplorato il ruolo predittivo degli antecedenti rispetto alle emozioni (R2: .06-.19) e delle emozioni rispetto alla comprensione di testi multipli online (R2: .12-.13). Gli antecedenti erano legati positivamente alla gioia (senso di efficacia: classe, \u3b2 = .23, p < .001; compiti per casa, \u3b2 = .24, p < .001; verifiche, \u3b2 = .19, p < .001; valore del compito: \u3b2 = .24, p < .001; \u3b2 = .22, p < .001; \u3b2 = .20, p < .001, rispettivamente) e negativamente alla noia (senso di efficacia: \u3b2 = -.23, p < .001; \u3b2 = -.15, p < .01; \u3b2 = -.20, p < .001; valore del compito: \u3b2 = -.30, p < .001; \u3b2 = -.27, p < .001; \u3b2 = -.32, p < .001) e all\u2019ansia (senso di efficacia: \u3b2 = -.18, p < .001; \u3b2 = -.23, p < .001; \u3b2 = -.22, p < .001; valore del compito: \u3b2 = -.12, p < .05; \u3b2 = -.13, p < .05; \u3b2 = -.11, p < .010). La comprensione di testi multipli online era legata positivamente alla gioia relativa ai compiti (\u3b2 = .17, p < .05) e negativamente alla noia relativa alle verifiche (\u3b2 = -.20, p < .05). Conclusioni. I risultati permettono di estendere la generalizzabilit\ue0 della teoria del controllo-valore alla comprensione di testi multipli online in bambini di scuola primaria. Tale conoscenza pu\uf2 essere utile nel pianificare interventi per promuovere abilit\ue0 di alfabetizzazione critiche nel XXI secolo, focalizzandosi sugli antecedenti motivazionali, emotivi e cognitivi
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