Critique by Design:Tackling Urban Renewal in the Design Studio

Cataloged from PDF version of article.The dominant mode of urbanization in our contemporary world is marked by large scale urban renewal projects, which are deployed with little or no consideration given to the social predicaments. The urban design studio can serve as a domain in which critical reflections on urban issues can be incorporated into design works. In this article, we propose a methodology of 'critique by design', which does not seek to arrive at scientific knowledge but rather involves the development of urban design proposals critically engaging with the urban issues they address through conceptual approaches. We discuss our methodology through the case of an experimental studio work conducted in Ankara, Turkey at Bilkent University, Department of Urban Design and Landscape Architecture in 2011

Reverse Engineering Gene Networks with ANN: Variability in Network Inference Algorithms

Motivation :Reconstructing the topology of a gene regulatory network is one of the key tasks in systems biology. Despite of the wide variety of proposed methods, very little work has been dedicated to the assessment of their stability properties. Here we present a methodical comparison of the performance of a novel method (RegnANN) for gene network inference based on multilayer perceptrons with three reference algorithms (ARACNE, CLR, KELLER), focussing our analysis on the prediction variability induced by both the network intrinsic structure and the available data. Results: The extensive evaluation on both synthetic data and a selection of gene modules of "Escherichia coli" indicates that all the algorithms suffer of instability and variability issues with regards to the reconstruction of the topology of the network. This instability makes objectively very hard the task of establishing which method performs best. Nevertheless, RegnANN shows MCC scores that compare very favorably with all the other inference methods tested. Availability: The software for the RegnANN inference algorithm is distributed under GPL3 and it is available at the corresponding author home page (http://mpba.fbk.eu/grimaldi/regnann-supmat

Angular momentum-Large-scale structure alignments in LCDM models and the SDSS

We study the alignments between the angular momentum of individual objects and the large-scale structure in cosmological numerical simulations and real data from the Sloan Digital Sky Survey, Data Release 6. To this end we measure anisotropies in the two point cross-correlation function around simulated halos and observed galaxies, studying separately the 1- and 2-halo regimes. The alignment of the angular momentum of dark-matter haloes in LCDM simulations is found to be dependent on scale and halo mass. At large distances (2-halo regime), the spins of high mass haloes are preferentially oriented in the direction perpendicular to the distribution of matter; lower mass systems show a weaker trend that may even reverse to show an angular momentum in the plane of the matter distribution. In the 1-halo term regime, the angular momentum is aligned in the direction perpendicular to the matter distribution; the effect is stronger than for the 1-halo term and increases for higher mass systems. On the observational side, we focus our study on galaxies in the Sloan Digital Sky Survey, Data Release 6 (SDSS-DR6) with elongated apparent shapes, and study alignments with respect to the major semi-axis. We find an excess of structure in the direction of the major semi-axis for all samples; the red sample shows the highest alignment (2.7+-0.08%) and indicates that the angular momentum of flattened spheroidals tends to be perpendicular to the large-scale structure. (Abridged)Comment: 10 pages, 6 figures, accepted for publication in MNRAS; the definitive version is available at www.blackwell-synergy.co

Evaluation and Validation of a Method for Determining Platelet Catecholamine in Patients with Obstructive Sleep Apnea and Arterial Hypertension

Background: Measurements of plasma and urinary catecholamine are susceptible to confounding factors that influence the results, complicating the interpretation of sympathetic nervous system (SNS) activity in the Obstructive sleep apnea (OSA) and arterial hypertension (HYP) conditions.Objective: in this study, we validated a test for platelet catecholamine and compared the catecholamine levels (adrenaline and noradrenaline) in urine, plasma and platelets in patients with OSA and HYP compared with controls.Methods: in the validation, 30 healthy, nonsmoking volunteers who were not currently undergoing treatment or medication were selected as the control group. One hundred fifty-four individuals (114 OSA, 40 non-OSA) were consecutively selected from the outpatient clinic of the Sleep Institute and underwent clinical, polysomnographic and laboratory evaluation, including the urinary, plasma and platelet levels of adrenaline (AD) and noradrenaline (NA). Patients were then allocated to groups according to the presence of OSA and/or hypertension.Results: A logistic regression model, controlled for age and BMI, showed that urinary AD and urinary NA were risk factors in the OSA+HYP group and the HYP group; however, the model showed higher levels of platelet NA for OSA without HYP. After 1 year of CPAP (continuous upper airway pressure) treatment, patients (n = 9) presented lower levels of urinary NA (p = 0.04) and platelet NA (p = 0.05).Conclusion: Urinary NA and AD levels were significantly associated with the condition of hypertension with and without OSA, whereas platelet NA with OSA without comorbidity. These findings suggest that platelet catecholamine levels might reflect nocturnal sympathetic activation in OSA patients without hypertension.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Associacao Fundo de Pesquisa a Psicobiologia (AFIP), BrazilConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Universidade Federal de São Paulo, Dept Psychobiol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Cardiol, São Paulo, BrazilAssoc Fundo Incent & Pesquisa, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Psychobiol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Cardiol, São Paulo, BrazilWeb of Scienc

Observational Diagnostics of Gas Flows: Insights from Cosmological Simulations

Galactic accretion interacts in complex ways with gaseous halos, including galactic winds. As a result, observational diagnostics typically probe a range of intertwined physical phenomena. Because of this complexity, cosmological hydrodynamic simulations have played a key role in developing observational diagnostics of galactic accretion. In this chapter, we review the status of different observational diagnostics of circumgalactic gas flows, in both absorption (galaxy pair and down-the-barrel observations in neutral hydrogen and metals; kinematic and azimuthal angle diagnostics; the cosmological column density distribution; and metallicity) and emission (Lya; UV metal lines; and diffuse X-rays). We conclude that there is no simple and robust way to identify galactic accretion in individual measurements. Rather, progress in testing galactic accretion models is likely to come from systematic, statistical comparisons of simulation predictions with observations. We discuss specific areas where progress is likely to be particularly fruitful over the next few years.Comment: Invited review to appear in Gas Accretion onto Galaxies, Astrophysics and Space Science Library, eds. A. J. Fox & R. Dave, to be published by Springer. Typos correcte

Gas Accretion and Star Formation Rates

Cosmological numerical simulations of galaxy evolution show that accretion of metal-poor gas from the cosmic web drives the star formation in galaxy disks. Unfortunately, the observational support for this theoretical prediction is still indirect, and modeling and analysis are required to identify hints as actual signs of star-formation feeding from metal-poor gas accretion. Thus, a meticulous interpretation of the observations is crucial, and this observational review begins with a simple theoretical description of the physical process and the key ingredients it involves, including the properties of the accreted gas and of the star-formation that it induces. A number of observations pointing out the connection between metal-poor gas accretion and star-formation are analyzed, specifically, the short gas consumption time-scale compared to the age of the stellar populations, the fundamental metallicity relationship, the relationship between disk morphology and gas metallicity, the existence of metallicity drops in starbursts of star-forming galaxies, the so-called G dwarf problem, the existence of a minimum metallicity for the star-forming gas in the local universe, the origin of the alpha-enhanced gas forming stars in the local universe, the metallicity of the quiescent BCDs, and the direct measurements of gas accretion onto galaxies. A final section discusses intrinsic difficulties to obtain direct observational evidence, and points out alternative observational pathways to further consolidate the current ideas.Comment: Invited review to appear in Gas Accretion onto Galaxies, Astrophysics and Space Science Library, eds. A. J. Fox & R. Dav\'e, to be published by Springe

The Psychological Impacts and Message Features of Health Misinformation: A Systematic Review of Randomized Controlled Trials

What does health misinformation look like, and what is its impact? We conducted a systematic review of 45 articles containing 64 randomized controlled trials (RCTs; N = 37,552) on the impact of health misinformation on behaviors and their psychological antecedents. We applied a planetary health perspective by framing environmental issues as human health issues and focusing on misinformation about diseases, vaccination, medication, nutrition, tobacco consumption, and climate change. We found that in 49% of the cases exposure to health misinformation damaged the psychological antecedents of behaviors such as knowledge, attitudes, or behavioral intentions. No RCTs evaluated the impact of exposure to misinformation on direct measures of health or pro-environmental behaviors (e.g., vaccination), and few studies explored the impact of misinformation on feelings, social norms, and trust. Most misinformation was based on logical fallacies, conspiracy theories, or fake experts. RCTs evaluating the impact of impossible expectations and cherry-picking are scarce. Most research focused on healthy adult US populations and used online samples. Future RCTs can build on our analysis and address the knowledge gaps we identified

The Psychological Impacts and Message Features of Health Misinformation

What does health misinformation look like, and what is its impact? We conducted a systematic review of 45 articles containing 64 randomized controlled trials (RCTs; N = 37,552) on the impact of health misinformation on behaviors and their psychological antecedents. We applied a planetary health perspective by framing environmental issues as human health issues and focusing on misinformation about diseases, vaccination, medication, nutrition, tobacco consumption, and climate change. We found that in 49% of the cases exposure to health misinformation damaged the psychological antecedents of behaviors such as knowledge, attitudes, or behavioral intentions. No RCTs evaluated the impact of exposure to misinformation on direct measures of health or pro-environmental behaviors (e.g., vaccination), and few studies explored the impact of misinformation on feelings, social norms, and trust. Most misinformation was based on logical fallacies, conspiracy theories, or fake experts. RCTs evaluating the impact of impossible expectations and cherry-picking are scarce. Most research focused on healthy adult US populations and used online samples. Future RCTs can build on our analysis and address the knowledge gaps we identified

Swift trust and commitment: the missing links for humanitarian supply chain coordination?

Coordination among actors in a humanitarian relief supply chain decides whether a relief operation can be or successful or not. In humanitarian supply chains, due to the urgency and importance of the situation combined with scarce resources, actors have to coordinate and trust each other in order to achieve joint goals. This paper investigated empirically the role of swift trust as mediating variable for achieving supply chain coordination. Based on commitment-trust theory we explore enablers of swift-trust and how swift trust translates into coordination through commitment. Based on a path analytic model we test data from the National Disaster Management Authority of India. Our study is the first testing commitment-trust theory (CTT) in the humanitarian context, highlighting the importance of swift trust and commitment for much thought after coordination. Furthermore, the study shows that information sharing and behavioral uncertainty reduction act as enablers for swift trust. The study findings offer practical guidance and suggest that swift trust is a missing link for the success of humanitarian supply chains

Printed Dot Quality in Response to Doctor Blade Angle in Gravure Printing

Doctor blade is one of the critical machine part of the gravure printing press that controls the amount of ink transfer on the substrate. The angle of the blade can be varied; however, an improper angle may cause major problems. In this study, the doctor blade angle was positioned at three different level to address its effect on the printed dot quality. Print trials were made on a web-fed gravure press at the speed of 650 ft./min. A high-resolution overhead camera was used to analyze the key dot attributes. The results showed that measuring only the density of printed dot –a traditional quality control method– is insufficient. Incorporating the camera was assisted capturing missing dots, as well as quantifying dot area, perimeter and circularity. Print trials showed that the image quality was undesirable, when the blade angle exceeded or fell behind the optimum position