2,412 research outputs found
An analysis of junior high school social studies textbooks for sociological content
Thesis (Ed. M.)--Boston University, 195
DES Y1 results:validating cosmological parameter estimation using simulated Dark Energy Surveys
Modification of DNA by aflatoxin B1 creates alkali-labile lesions in DNA at positions of guanine and adenine.
Structural basis for recruitment of mitochondrial fission complexes by Fis1
Mitochondrial fission controls mitochondrial shape and physiology, including mitochondrial remodeling in apoptosis. During assembly of the yeast mitochondrial fission complex, the outer membrane protein Fis1 recruits the dynamin-related GTPase Dnm1 to mitochondria. Fis1 contains a tetratricopeptide repeat (TPR) domain and interacts with Dnm1 via the molecular adaptors Mdv1 and Caf4. By using crystallographic analysis of adaptor-Fis1 complexes, we show that these adaptors use two helices to bind to both the concave and convex surfaces of the Fis1 TPR domain. Fis1 therefore contains two interaction interfaces, a binding mode that, to our knowledge, has not been observed previously for TPR domains. Genetic and biochemical studies indicate that both binding interfaces are important for binding of Mdv1 and Caf4 to Fis1 and for mitochondrial fission activity in vivo. Our results reveal how Fis1 recruits the mitochondrial fission complex and will facilitate efforts to manipulate mitochondrial fission
Excitonic Effects in Quantum Wires
We review the effects of Coulomb correlation on the linear and non-linear
optical properties of semiconductor quantum wires, with emphasis on recent
results for the bound excitonic states. Our theoretical approach is based on
generalized semiconductor Bloch equations, and allows full three-dimensional
multisubband description of electron-hole correlation for arbitrary confinement
profiles. In particular, we consider V- and T-shaped structures for which
significant experimental advances were obtained recently. Above band gap, a
very general result obtained by this approach is that electron-hole Coulomb
correlation removes the inverse-square-root single-particle singularity in the
optical spectra at band edge, in agreement with previous reports from purely
one-dimensional models. Strong correlation effects on transitions in the
continuum are found to persist also at high densities of photoexcited carriers.
Below bandgap, we find that the same potential- (Coulomb) to kinetic-energy
ratio holds for quite different wire cross sections and compositions. As a
consequence, we identify a shape- and barrier-independent parameter that
governs a universal scaling law for exciton binding energy with size. Previous
indications that the shape of the wire cross-section may have important effects
on exciton binding are discussed in the light of the present results.Comment: Proc. OECS-5 Conference, G\"ottingen, 1997 (To appear in Phys. Stat.
Sol. (b)
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