Justicia organizacional y compromiso laboral de los servidores administrativos del Servicio Nacional de Meteorología e Hidrología del Perú – SENAMHI, Lima - 2017

Este trabajo de investigación llamado “Justicia organizacional y compromiso laboral de los servidores administrativos del Servicio Nacional de Meteorología e Hidrología del Perú – SENAMHI, Lima 2017”; presento como problema general la siguiente interrogante: ¿Qué relación existe entre justicia organizacional y el compromiso laboral de los servidores administrativos del Servicio Nacional de Meteorología e Hidrología del Perú – SENAMHI, Lima - 2017?, y como objetivo general el determinar la relación existente entre justicia organizacional y el compromiso laboral de los servidores administrativos del Servicio Nacional de Meteorología e Hidrología del Perú – SENAMHI, Lima - 2017. La metodología de la investigación es de tipo básico. Siendo de nivel descriptivo, correlacional y de diseño no experimental de corte transversal. Nuestra población estuvo formada por 49 servidores administrativos del SENAMHI. El tipo de muestra fue probabilístico aleatoria conformada por 32 servidores. La primera variable justicia organizacional, medida por evaluación de dicha variable por medio de un instrumento, acoplada y enmarcada a la realidad del estudio; la variable compromiso laboral que es la segunda variable del estudio también tuvo el mismo trato científico. Se concluyó, basado en la relación Rho de Spearman = 0,369 y un nivel de significancia de p = 0,009 que es menor a α = 0,05, que la justicia organizacional se relaciona directa y significativamente con el compromiso laboral del SENAMHI

Serologic Evidence that Ascaris and Toxoplasma Infections Impact Inflammatory Responses to Helicobacter pylori in Colombians

Background: Helicobacter pylori-infected children from coastal Tumaco, Colombia, have more parasitism, and adults have lower gastric cancer risk compared with high-altitude Pasto/Tuquerres residents. Because helminth and Toxoplasma gondii infections alter helicobacter gastritis in rodent models, we determined whether seropositivity to Ascaris lumbricoides or T. gondii was associated with Th2-IgG1 or Th1-IgG2 responses to H. pylori. Methods: Sera (240) from the two populations were evaluated for A. lumbricoides and T. gondii seropositivity and results correlated with IgE and IgG isotype responses to H. pylori. Results: Most Tumaco children and adults were seropositive for A. lumbricoides (89%, 66%), T. gondii (59%, 98%), or both (45%, 66%). In contrast, seropositivity among Pasto/Tuquerres children was much lower (9%A. lumbricoides, 11%T. gondii, and 2% dual positive) but increased in adults (58%A. lumbricoides, 82%T. gondii, and 41% dual positive). A. lumbricoides seropositivity correlated with elevated IgE and anti-inflammatory Th2-IgG1 responses to H. pylori, while T. gondiigondii seropositivity was linked to elevated IgE, pro-inflammatory Th1-IgG2, IgG3, and IgG4 responses to H. pylori. Individuals with high T. gondii titers had reduced Th1-IgG2, IgG3, and IgG4 responses to H. pylori. Conclusions: Results support regional differences for childhood parasitism and indicate A. lumbricoides and T. gondii infections may impact inflammatory responses to H. pylori and partially explain differences in gastric cancer risk in Colombia.National Institutes of Health (U.S.) (Grant T32RR07036)National Institutes of Health (U.S.) (Grant PO1CA028842)National Institutes of Health (U.S.) (Grant P30ES02109

Evolución del desempeño financiero de las empresas del sector cárnico bovino del departamento de Córdoba en el período 2012- 2015: una mirada desde el neopatrimonialismo

Este artículo tiene como principal intención evaluar la evolución del desempeño financiero de empresas del sector cárnico bovino en el departamento de Córdoba (Colombia) a la luz del análisis desde la teoría neopatrimonial. El enfoque metodológico abordado es el estudio de caso sobre profundidad descriptiva, con resultados para las empresas Frigosinú S.A. y Red Cárnica S.A.S., que representan la mayor participación del mercado cárnico de la región. Por ser un análisis novedoso, del cual no hay evidencia empírica para el país, se contrastó el modelo de análisis financiero neopatrimonialista con el análisis financiero tradicional. Los hallazgos indican que ambas empresas, desde el punto de vista de los modelos, requieren aumentar su margen de utilidades para soportar su estructura de costos a través de una gestión eficiente de la administración, y que presentan severos problemas que pueden llevar a colapsar los sistemas de operación desde la perspectiva financiera

Sex Hormones, Hormonal Interventions, and Gastric Cancer Risk: A Meta-analysis

Estrogens may influence gastric cancer risk but published studies are inconclusive. We therefore performed a meta-analysis addressing the associations of gastric cancer in women with menstrual and reproductive factors, and with use of estrogen- and antiestrogen-related therapies. Searches of PubMed up to June, 2011 and review of citations yielded a total of 28 independent studies including at least one exposure of interest. Random effects pooled estimates of relative risk (RR) and corresponding 95% confidence intervals (CI) were calculated for eight exposures reported in at least five studies, including: age at menarche, age at menopause, years of fertility, parity, age at first birth, oral contraceptive use, hormone replacement therapy (HRT), and tamoxifen treatment. Longer years of fertility (RR= 0.74; 95% CI= 0.63 to 0.86) and HRT (RR= 0.77, 95% CI= 0.64 to 0.92) were each associated with decreased gastric cancer risk. Conversely, tamoxifen treatment was associated with increased risk (RR= 1.82, 95% CI= 1.39 to 2.38). The other five exposures were not significantly associated. Our analysis supports the hypothesis that longer exposure to estrogen effects of either ovarian or exogenous origin may decrease risk of gastric cancer. Additional studies are warranted to extend this finding and to identify the underlying mechanisms

Helicobacter pylori causes Hyperproliferation of the gastric Epithelium: Pre- and Post-Eradication indices of proliferating cell nuclear antigen

Artículo científico -- Universidad de Costa Rica, Instituto de Investigaciones en Salud. 1993To assess the effect of Helicobacter pylori (HP) eradication on the proliferation of the gastric epithelium by the expression of the proliferating cell nuclear antigen (PCNA). Methods: Alcohol-fixed gastric biopsies taken before and after treatment for HP were immunostained with the PC-10 anti-PCNA monoclonal antibody and the labeling index was determined with an image analysis system. Results: The mean PCNA-labeling index (LI) of 16 patients who remained HP positive did not change significantly (18.95 ± 1.71 on first visit vs. 17.96 ± 1.91 on second visit, mean ± SEM). The mean PCNA LI of 31 patients who cleared HP was reduced significantly (19.95 ± 1.77 on first visit vs. 14.13 ± 1.29 on second visit, p < 0.001). Patients who were positive for HP at both first and second visit showed a significantly higher PCNA LI than normal control biopsies (13.05 ± 1.70) (p < 0.05). Conclusions: These results indicate that the gastric mucosa infected with HP is in a state of hyperproliferation. Patients who cleared HP showed a significant histopathological improvement, reflected in the reduction in number of polymorphonuclear and mononuclear cell infiltrates, and a reduction in the amount of superficial mucosa damage. Prolonged hyperproliferation of the gastric epithelium exerted by HP infection could be a major factor for human gastric carcinogenesis.Universidad de Costa Rica. Instituto de Investigaciones en SaludLouisiana State University Medical Center. Department of PathologyUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA

Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans

Peer reviewedPreprin

Evolutionary History of the Helicobacter pylori Genome: Implications for Gastric Carcinogenesis

The genome of the bacterium Helicobacter pylori has evolved over the millennia since its migration out of Africa along with its human host approximately 60,000 years ago. Human migrations, after thousands of years of permanent settlement in those lands, resulted in seven prototypes of genetic populations of H. pylori with distinct geographical distributions. In all continents, present day isolates of H. pylori have molecular markers that reflect population migrations. The colonization of the Americas as well as the slave trade introduced European and African strains to the New World. The relationship between H. pylori genome and gastric cancer rates is linked to the presence of the cagA gene, but the knowledge on this subject is incomplete because other genes may be involved in certain populations. A new situation for Homo sapiens is the absence of H. pylori colonization in certain, mostly affluent, populations, apparently brought about by improved home sanitation and widespread use of antibiotics during the last decades. The disappearance of H. pylori from the human microbiota may be linked to emerging epidemics of esophageal adenocarcinoma, some allergic diseases such as asthma and some autoimmune disorders

Epidemiologia do câncer do esôfago em São Paulo, Brasil

Aspects of the incidente of cancer of the oesophagus in residents of the city of S. Paulo, Brazil, for 1975, are examined. Data collected by the Cancer Registry yield a rate of 6.4/100,000 and 1.3/100,000 for males and females, respectively; when adjusted to the &laquo;world-population&raquo; the rates are 9.2/100,000 and 2.0/100,000. Male rates put S. Paulo at higher risk than three other Brazilian cities with known data, namely Fortaleza, Recife and Rio de Janeiro; for females there is no strong indication of differences, except in the case of Fortaleza. The specific age-sex incidence curves conform well to the pattern described by Higginson and Muir; values for the curves of 1nI (age-specific rate) at ages 35 through 75 were 5.7 for males and 4.4 for females, when adjusting a straight line. S. Paulo city natives present a lower incidence than people born elsewhere; for the two categories of migrants within Brazil, living in S. Paulo, the age-specific incidence rates for males are consistently very high. Male-female ratio patterns are fairly regular among the three Brazilian groups; the foreign-born present higher ratios.São examinados aspectos da incidência de câncer do esôfago para residentes no município de São Paulo, (Brasil), no ano de 1975. Dados coletados pelo Registro de Câncer mostram um coeficiente de 6,4 e 1,3 por cem mil homens e mulheres, respectivamente; quando padronizados pela "população mundial" os coeficientes são 9,2 e 2,0 por cem mil. As taxas do sexo masculino mostram que São Paulo está a um nível de risco maior do que outras três cidades brasileiras, com dados conhecidos, Fortaleza, Recife e Rio de Janeiro; no sexo feminino não há evidências de diferenças, a não ser possivelmente em relação a Fortaleza. As curvas de incidência específica segundo idade e sexo concordam com o padrão descrito por Higginson e Muir; valores para a inclinação do 1nI (incidência específica por idade) nas idades 35 a 75 foram 5,7 para o sexo masculino e 4,4 para o feminino, ajustando-se uma linha reta. Os nativos de São Paulo apresentam uma menor incidência do que os nascidos fora da cidade; para as duas categorias de imigrantes brasileiros residentes de São Paulo, as incidências para homens são consistentemente altas. As razões masculino-feminino de incidência apresentam regularidade nos grupos brasileiros; entre os estrangeiros as razões são maiores

Non-alcoholic beverages and risk of bladder cancer in Uruguay

BACKGROUND: Bladder cancer is the fourth most frequent malignancy among Uruguayan men. A previous study from Uruguay suggested a high risk of bladder cancer associated with maté drinking. We conducted an additional case-control study in order to further explore the role of non-alcoholic beverages in bladder carcinogenesis. METHODS: In the time period 1996–2000, 255 incident cases with transitional cell carcinoma of the bladder and 501 patients treated in the same hospitals and in the same time period were frequency matched on age, sex, and residence. Both cases and controls were face-to-face interviewed on occupation, tobacco smoking, alcohol drinking and intake of maté, coffee, tea, and soft drinks. Statistical analysis was carried out by unconditional multiple logistic regression. RESULTS: Ever maté drinking was positively associated with bladder cancer (odds ratio [OR] 2.2, 95% confidence interval [CI] 1.2–3.9) and the risk increased for increasing duration and amount of maté drinking. Both coffee and tea were strongly associated with bladder cancer risk (OR for coffee drinking 1.6, 95% CI 1.2–2.3; OR for tea drinking 2.3, 95% CI 1.5–3.4). These results were confirmed in a separate analysis of never-smokers. CONCLUSION: Our results suggest that drinking of maté, coffee and tea may be risk factors for bladder carcinoma in Uruguay

Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV

The performance of muon reconstruction, identification, and triggering in CMS has been studied using 40 inverse picobarns of data collected in pp collisions at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection criteria covering a wide range of physics analysis needs have been examined. For all considered selections, the efficiency to reconstruct and identify a muon with a transverse momentum pT larger than a few GeV is above 95% over the whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4, while the probability to misidentify a hadron as a muon is well below 1%. The efficiency to trigger on single muons with pT above a few GeV is higher than 90% over the full eta range, and typically substantially better. The overall momentum scale is measured to a precision of 0.2% with muons from Z decays. The transverse momentum resolution varies from 1% to 6% depending on pseudorapidity for muons with pT below 100 GeV and, using cosmic rays, it is shown to be better than 10% in the central region up to pT = 1 TeV. Observed distributions of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO