The Effects of Native and Domestic Grazers on the Health of Bumble Bee (Bombus spp.) Populations in a Historical Tallgrass Prairie Ecosystem

Bumble bees (Bombus spp.) play an important role in the pollination of ecologically and economically significant plants worldwide. In recent years, bumble bee populations have suffered decline throughout North America, particularly in the Midwest. Many factors likely contribute to this decline, including the use of pesticides, disease, and habitat loss. Although cattle grazing space is a common use for Midwestern grassland, a comparison had not been made between the capacity of cattle pasture to support bumble bee communities with the capacity of tallgrass prairie, a habitat thought to be optimal for requisite floral resources. Additionally, the reintroduction of bison is becoming increasingly prevalent in the Midwest, both as a restoration tool and as a farmed meat, but it is not known if there is an effect of bison grazing on bumble bee communities. In this study, we sought to determine what effects grassland management for restored prairie, cattle pasture, and bison pasture have on the community composition of bumble bees at Midewin National Tallgrass Prairie in northeastern Illinois. Abundance, species richness, and diversity were recorded across transects in each habitat type using standard sweep net protocol. We found that restored prairie supports significantly higher abundance and species richness of bumble bees than either cattle or bison pasture. This study can be used to inform grassland managers of conservation implications when making land use decisions in the face of habitat loss and decline of bumble bees across the Midwest

Graphical Encoding of a Spatial Logic for the pi-Calculus

This paper extends our graph-based approach to the verification of spatial properties of π-calculus specifications. The mechanism is based on an encoding for mobile calculi where each process is mapped into a graph (with interfaces) such that the denotation is fully abstract with respect to the usual structural congruence, i.e., two processes are equivalent exactly when the corresponding encodings yield isomorphic graphs. Behavioral and structural properties of π-calculus processes expressed in a spatial logic can then be verified on the graphical encoding of a process rather than on its textual representation. In this paper we introduce a modal logic for graphs and define a translation of spatial formulae such that a process verifies a spatial formula exactly when its graphical representation verifies the translated modal graph formula

Stable Control of Pulse Speed in Parametric Three-Wave Solitons

We analyze the control of the propagation speed of three wave packets interacting in a medium with quadratic nonlinearity and dispersion. We found analytical expressions for mutually trapped pulses with a common velocity in the form of a three-parameter family of solutions of the three-wave resonant interaction. The stability of these novel parametric solitons is simply related to the value of their common group velocity

Arboricity, h-Index, and Dynamic Algorithms

In this paper we present a modification of a technique by Chiba and Nishizeki [Chiba and Nishizeki: Arboricity and Subgraph Listing Algorithms, SIAM J. Comput. 14(1), pp. 210--223 (1985)]. Based on it, we design a data structure suitable for dynamic graph algorithms. We employ the data structure to formulate new algorithms for several problems, including counting subgraphs of four vertices, recognition of diamond-free graphs, cop-win graphs and strongly chordal graphs, among others. We improve the time complexity for graphs with low arboricity or h-index.Comment: 19 pages, no figure

Activation and degranulation of CAR-T cells using engineered antigen-presenting cell surfaces

Adoptive cell transfer of Chimeric Antigen Receptor (CAR)-T cells showed promising results in patients with B cell malignancies. However, the detailed mechanism of CAR-T cell interaction with the target tumor cells is still not well understood. This work provides a systematic method for analyzing the activation and degranulation of second-generation CAR-T cells utilizing antigen-presenting cell surfaces. Antigen-presenting cell surfaces composed of circular micropatterns of CAR-specific anti-idiotype antibodies have been developed to mimic the interaction of CAR-T cells with target tumor cells using micro-contact printing. The levels of activation and degranulation of fixed non-transduced T cells (NT), CD19.CAR-T cells, and GD2.CAR-T cells on the antigen-presenting cell surfaces were quantified and compared by measuring the intensity of the CD3ζ chain phosphorylation and the Lysosome-Associated Membrane Protein 1 (LAMP-1), respectively. The size and morphology of the cells were also measured. The intracellular Ca2+ flux of NT and CAR-T cells upon engagement with the antigen-presenting cell surface was reported. Results suggest that NT and CD19.CART cells have comparable activation levels, while NT have higher degranulation levels than CD19.CAR-T cells and GD2.CAR-T cells. The findings show that antigen-presenting cell surfaces allow a quantitative analysis of the molecules involved in synapse formation in different CAR-T cells in a systematic, reproducible manner

On the relationship between standard intersection cuts, lift-and-project cuts, and generalized intersection cuts

We examine the connections between the classes of cuts in the title. We show that lift-and-project (L&P) cuts from a given disjunction are equivalent to generalized intersection cuts from the family of polyhedra obtained by taking positive combinations of the complements of the inequalities of each term of the disjunction. While L&P cuts from split disjunctions are known to be equivalent to standard intersection cuts (SICs) from the strip obtained by complementing the terms of the split, we show that L&P cuts from more general disjunctions may not be equivalent to any SIC. In particular, we give easily verifiable necessary and sufficient conditions for a L&P cut from a given disjunction D to be equivalent to a SIC from the polyhedral counterpart of D. Irregular L&P cuts, i.e. those that violate these conditions, have interesting properties. For instance, unlike the regular ones, they may cut off part of the corner polyhedron associated with the LP solution from which they are derived. Furthermore, they are not exceptional: their frequency exceeds that of regular cuts. A numerical example illustrates some of the above properties. © 2016 Springer-Verlag Berlin Heidelberg and Mathematical Optimization Societ

The magnitude of postconvulsive leukocytosis mirrors the severity of periconvulsive respiratory compromise : a single center retrospective study

Background: Generalized epileptic convulsions frequently exhibit transient respiratory symptoms and non-infectious leukocytosis. While these peri-ictal effects appear to arise independently from one another, the possibility that they stem from a common ictal pathophysiological response has yet to be explored. We aimed to investigate whether peri-ictal respiratory symptoms and postictal leukocytosis coexist. Methods: We performed a single center retrospective chart review of 446 patients brought to our emergency department between January 1, 2017 and August 23, 2018 for the care of generalized epileptic convulsions with or without status epilepticus. We included 152 patients who were stratified based on the presence (PeCRC+) or absence (PeCRC-) of overt periconvulsive respiratory compromise (PeCRC). In addition, patients were stratified based on the presence or absence of postconvulsive leukocytosis (PoCL), defined as an initial postconvulsive white blood cell (WBC) count ≥ 11,000 cells/mm3. Triage vital signs, and chest x ray (CXR) abnormalities were also examined. Results: Overt PeCRC was observed in 31.6% of patients, 43% of whom required emergent endotracheal intubations. PoCL was observed in 37.5% of patients, and was more likely to occur in PeCRC+ than in PeCRC- patients (79.2 vs. 18.2%; OR = 17.0; 95% CI = 7.2-40.9; p < 0.001). Notably, the magnitude of PoCL was proportional to the severity of PeCRC, as the postconvulsive WBC count demonstrated a negative correlation with triage hemoglobin oxygen saturation (R = -0.22; p < 0.01; CI = -0.48 to -0.07). Moreover, a receiver operating characteristic analysis of the WBC count's performance as predictor of endotracheal intubation reached a significant area under the curve value of 0.81 (95% CI = 0.71-0.90; p < 0.001). Finally, PeCRC+ patients demonstrated frequent CXR abnormalities, and their postconvulsive WBC counts correlated directly with triage heart rate (R = 0.53; p < 0.001). Conclusion: Our data support the existence of an ictal pathophysiological response, which induces proportional degrees of PoCL and PeCRC. We suggest this response is at least partially propelled by systemic catecholamines

An unusual presentation of genital herpes in a patient affected by lichen sclerosus et atrophicus: A case report and a combined treatment proposal

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