529 research outputs found
Visual Ontology Cleaning: Cognitive Principles and Applicability
In this paper we connect two research areas, the Qualitative
Spatial Reasoning and visual reasoning on ontologies. We discuss the logical
limitations of the mereotopological approach to the visual ontology
cleaning, from the point of view of its formal support. The analysis is
based on three different spatial interpretations wich are based in turn on
three different spatial interpretations of the concepts of an ontology.Ministerio de Educación y Ciencia TIN2004-0388
Similarities and differences in lipidomics profiles among healthy monozygotic twin pairs.
Differences in genetic background and/or environmental exposure among individuals are expected to give rise to differences in measurable characteristics, or phenotypes. Consequently, genetic resemblance and similarities in environment should manifest as similarities in phenotypes. The metabolome reflects many of the system properties, and is therefore an important part of the phenotype. Nevertheless, it has not yet been examined to what extent individuals sharing part of their genome and/or environment indeed have similar metabolomes. Here we present the results of hierarchical clustering of blood plasma lipid profile data obtained by liquid chromatographymass spectrometry from 23 healthy, 18-year-old twin pairs, of which 21 pairs were monozygotic, and 8 of their siblings. For 13 monozygotic twin pairs, within-pair similarities in relative concentrations of the detected lipids were indeed larger than the similarities with any other study participant. We demonstrate such high coclustering to be unexpected on basis of chance. The similarities between dizygotic twins and between nontwin siblings, as well as between nonfamilial participants, were less pronounced. In a number of twin pairs, within-pair dissimilarity of lipid profiles positively correlated with increased blood plasma concentrations of C-reactive protein in one twin. In conclusion, this study demonstrates that in healthy individuals, the individual genetic background contributes to the blood plasma lipid profile. Furthermore, lipid profiling may prove useful in monitoring health status, for example, in the context of personalized medicine. © 2008 Mary Ann Liebert, Inc. Chemicals / CAS: C-Reactive Protein, 9007-41-4; Lipid
Normal-state conductivity in underdoped La_{2-x}Sr_xCuO_4 thin films: Search for nonlinear effects related to collective stripe motion
We report a detailed study of the electric-field dependence of the
normal-state conductivity in La_{2-x}Sr_xCuO_4 thin films for two
concentrations of doped holes, x=0.01 and 0.06, where formation of diagonal and
vertical charged stripes was recently suggested. In order to elucidate whether
high electric fields are capable of depinning the charged stripes and inducing
their collective motion, we have measured current-voltage characteristics for
various orientations of the electric field with respect to the crystallographic
axes. However, even for the highest possible fields (~1000 V/cm for x=0.01 and
\~300 V/cm for x=0.06) we observed no non-linear-conductivity features except
for those related to the conventional Joule heating of the films. Our analysis
indicates that Joule heating, rather than collective electron motion, may also
be responsible for the non-linear conductivity observed in some other 2D
transition-metal oxides as well. We discuss that a possible reason why moderate
electric fields fail to induce a collective stripe motion in layered oxides is
that fairly flexible and compressible charged stripes can adjust themselves to
the crystal lattice and individual impurities, which makes their pinning much
stronger than in the case of conventional rigid charge-density waves.Comment: 10 pages, 10 figures, accepted for publication in Phys. Rev.
Two-dimensional superstrings and the supersymmetric matrix model
We present evidence that the supersymmetric matrix model of Marinari and
Parisi represents the world-line theory of N unstable D-particles in type II
superstring theory in two dimensions. This identification suggests that the
matrix model gives a holographic description of superstrings in a
two-dimensional black hole geometry.Comment: 22 pages, 2 figures; v2: corrected eqn 4.6; v3: corrected appendices
and discussion of vacua, added ref
Measurement of the Charged Multiplicities in b, c and Light Quark Events from Z0 Decays
Average charged multiplicities have been measured separately in , and
light quark () events from decays measured in the SLD experiment.
Impact parameters of charged tracks were used to select enriched samples of
and light quark events, and reconstructed charmed mesons were used to select
quark events. We measured the charged multiplicities:
,
, from
which we derived the differences between the total average charged
multiplicities of or quark events and light quark events: and . We compared
these measurements with those at lower center-of-mass energies and with
perturbative QCD predictions. These combined results are in agreement with the
QCD expectations and disfavor the hypothesis of flavor-independent
fragmentation.Comment: 19 pages LaTex, 4 EPS figures, to appear in Physics Letters
Schreier type theorems for bicrossed products
We prove that the bicrossed product of two groups is a quotient of the
pushout of two semidirect products. A matched pair of groups is deformed using a combinatorial datum consisting of
an automorphism of , a permutation of the set and a
transition map in order to obtain a new matched pair such that there exist an -invariant
isomorphism of groups . Moreover, if we fix the group and the automorphism
\sigma \in \Aut(H) then any -invariant isomorphism between two
arbitrary bicrossed product of groups is obtained in a unique way by the above
deformation method. As applications two Schreier type classification theorems
for bicrossed product of groups are given.Comment: 21 pages, final version to appear in Central European J. Mat
Characterization of the peripheral thyroid system of gilthead seabream acclimated to different ambient salinities
Thyroid hormones are involved in many developmental and physiological processes, including osmoregulation. The regulation of the thyroid system by environmental salinity in the euryhaline gilthead seabream (Sparus aurata) is still poorly characterized. To this end seabreams were exposed to four different environmental salinities (5, 15, 40 and 55 ppt) for 14 days, and plasma free thyroid hormones (fT3, ff4), outer ring deiodination and Na+/K+ -ATPase activities in gills and kidney, as well as other osmoregulatory and metabolic parameters were measured. Low salinity conditions (5 ppt) elicited a significant increase in fT3 (29%) and ff4 (184%) plasma concentrations compared to control animals (acclimated to 40 ppt, natural salinity conditions in the Bay of Cadiz, Spain), while the amount of pituitary thyroid stimulating hormone subunit 13 (tshb) transcript abundance remained unchanged. In addition, plasma fT4 levels were positively correlated to renal and branchial deiodinase type 2 (dio2) mRNA expression. Gill and kidney T4-outer ring deiodination activities correlated positively with dio2 mRNA expression and the highest values were observed in fish acclimated to low salinities (5 and 15 ppt). The high salinity (55 ppt) exposure caused a significant increase in tshb expression (65%), but deiodinase gene expression (diol and dio2) and activity did not change and were similar to controls (40 ppt). In conclusion, acclimation to different salinities led to changes in the peripheral regulation of thyroid hormone metabolism in seabream. Therefore, thyroid hormones are involved in the regulation of ion transport and osmoregulatory physiology in this species. The conclusions derived from this study may also allow aquaculturists to modulate thyroid metabolism in seabream by adjusting culture salinity. (C) 2016 Elsevier Inc. All rights reserved.Socrates/Erasmus Grant from the European UnionUniversity of Cadiz [UCA 2009-074-FPI]Ministerio de Education y Ciencia, Spain [AGL2007-61211/ACU]FEDER, Spain [AGL2007-61211/ACU]Proyecto de Excelencia (Junta de Andalucia) [PO7-RNM-02843]Science Foundation (FCT) of Portugal [SFRH/BPD/89889/2012, SFRH/BPD/84033/2012]info:eu-repo/semantics/acceptedVersio
Measurement of the B0-anti-B0-Oscillation Frequency with Inclusive Dilepton Events
The - oscillation frequency has been measured with a sample of
23 million \B\bar B pairs collected with the BABAR detector at the PEP-II
asymmetric B Factory at SLAC. In this sample, we select events in which both B
mesons decay semileptonically and use the charge of the leptons to identify the
flavor of each B meson. A simultaneous fit to the decay time difference
distributions for opposite- and same-sign dilepton events gives ps.Comment: 7 pages, 1 figure, submitted to Physical Review Letter
- …