Patrimonialización del pasado francés en la pequeña ciudad pampeana de Pigüé: Un recurso para la identidad y el desarrollo local

Patrimonialización del pasado francés en la pequeña ciudad pampeana de Pigüé: Un recurso para la identidad y el desarrollo loca

Réinterprétation sociale locale et mémoires familiales de l’immigration aveyronnaise à Pigüé (Province de Buenos Aires, Argentine)

Réinterprétation sociale locale et mémoires familiales de l’immigration aveyronnaise à Pigüé (Province de Buenos Aires, Argentine

Patrimonialisation of the French heritage in Pigüé, a small Pampeana city. A resource for identity and local development

Este artículo analiza los procesos de construcción de la identidad de un territorio y como los actores locales consiguen trasladar y aumentar un patrimonio cultural de un pasado migratorio singular desde la esfera privada de familias o de una comunidad particular a la esfera pública local. Tomamos el caso del presente del pasado inmigratorio francés de la pequeña ciudad de Pigüé (17.000 habitantes), en el partido de Saavedra (Provincia de Buenos Aires). La sociedad tomó conciencia de este pasado como recurso identitario en 1984 con los festejos del centenario de su fundación. Luego, la cooperación cultural con Francia permitió a algunos que lo habían olvidado descubrir o valorizar su pasado familiar y para varios otros, de origen francés o no, crear nuevos vínculos con Francia y con el pasado del territorio. Se realizaron trece entrevistas semi-dirigidas a actores claves de este proceso, movilizando el análisis temático transversal de los relatos. Concluimos que se logró impulsar una construcción de una memoria social local en el presente del pasado francés como recurso territorial más allá de la comunidad de origen. Ese recurso, que se constituye en patrimonio, es susceptible hoy ser aprovechado económicamente para el desarrollo local con menos riesgos de padecer reinterpretaciones comerciales o folklorizantes.This article analyses the processes of building the identity of a territory and the way local actors manage and increase a cultural heritage from a unique migratory past going from the private sphere of families or a particular community to the local public sphere. We take the case of the present of the French immigrant in the small town of Pigüé (17,000 inhabitants), in Saavedra district (Province of Buenos Aires). The society became aware of this past as an identity resource in 1984 with the centennial celebrations of the town foundation. Cultural cooperation with France allowed some people to fi nd it, discover or value their family background, and for several others, of French origin or not, to create new links with France and the past of the territory. Fifteen semi-structured interviews were conducted with the key actors of this process, giving way to the transversal thematic analysis of the recorded stories. We conclude that a construction of a local social memory was achieved in the present of the French past as a territorial resource beyond the community of origin. This resource, which is constituted as patrimony, is likely to be used economically for local development with minor risks of commercial or folklorising reinterpretations.Fil: Albaladejo, Christophe Jacques. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Instituto Multidisciplinario de Historia y Ciencias Humanas; ArgentinaFil: Sassone, Susana Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Instituto Multidisciplinario de Historia y Ciencias Humanas; ArgentinaFil: Bustos Cara, Roberto Nicolas. Universidad Nacional del Sur. Departamento de Geografía y Turismo; Argentin

Les agricultures paysannes extrapampéennes argentines. Au-delà des résistances

L’agriculture est-elle toujours une affaire de famille ? Cet ouvrage analyse les transformations du caractère familial de l’agriculture en France, mises en perspective avec quelques éclairages de situations dans les pays du Sud. La première partie de l’ouvrage rend compte des recompositions de l’exploitation agricole et de ses enjeux, exploitation qui est de moins en moins familiale, tout en le restant. Elle propose des cadres d’analyse élargis pour les appréhender. Les transformations des formes familiales d’agriculture sont abordées dans une deuxième partie par l’étude des mutations qui s’opèrent dans le travail en agriculture. Ces mutations amènent à questionner le sens du travail et les interfaces avec le vivre en famille et les activités non-agricoles, au-delà des seules problématiques d’organisation et de performances technico-économiques. La troisième partie de l’ouvrage montre que les cadres structurant l’activité agricole dépassent le champ de la famille et se renouvellent, en particulier dans les formes d’insertion territoriale, dans les modalités des processus d’innovation et par des reconfigurations de l’action collective de proximité. Finalement, les transformations du caractère familial, saisies dans le temps long des trajectoires d’exploitations, sont aussi observées dans les formes et stratégies de pérennisation et de transmission, qu’il s’agisse de transmettre un statut, une activité, une entreprise, un patrimoine, un outil de production ou encore des savoir-faire. Une synthèse conclusive propose un renouvellement des questions de recherche et plaide pour un décloisonnement des études en agriculture. L’ouvrage rassemble des travaux de recherche récents de chercheurs issus du département Sciences pour l’action et le développement (Sad) de l’Inra et de ses partenaires scientifiques et professionnels. Il fait une large place à des travaux de jeunes chercheurs et à des thèses récemment soutenues. D’abord destiné aux chercheurs et enseignants-chercheurs, il s’adresse également aux organisations professionnelles (instituts techniques, réseaux associatifs, syndicats, chambres d’agriculture, etc.)

High precision astrometry mission for the detection and characterization of nearby habitable planetary systems with the Nearby Earth Astrometric Telescope (NEAT)

(abridged) A complete census of planetary systems around a volume-limited sample of solar-type stars (FGK dwarfs) in the Solar neighborhood with uniform sensitivity down to Earth-mass planets within their Habitable Zones out to several AUs would be a major milestone in extrasolar planets astrophysics. This fundamental goal can be achieved with a mission concept such as NEAT - the Nearby Earth Astrometric Telescope. NEAT is designed to carry out space-borne extremely-high-precision astrometric measurements sufficient to detect dynamical effects due to orbiting planets of mass even lower than Earth's around the nearest stars. Such a survey mission would provide the actual planetary masses and the full orbital geometry for all the components of the detected planetary systems down to the Earth-mass limit. The NEAT performance limits can be achieved by carrying out differential astrometry between the targets and a set of suitable reference stars in the field. The NEAT instrument design consists of an off-axis parabola single-mirror telescope, a detector with a large field of view made of small movable CCDs located around a fixed central CCD, and an interferometric calibration system originating from metrology fibers located at the primary mirror. The proposed mission architecture relies on the use of two satellites operating at L2 for 5 years, flying in formation and offering a capability of more than 20,000 reconfigurations (alternative option uses deployable boom). The NEAT primary science program will encompass an astrometric survey of our 200 closest F-, G- and K-type stellar neighbors, with an average of 50 visits. The remaining time might be allocated to improve the characterization of the architecture of selected planetary systems around nearby targets of specific interest (low-mass stars, young stars, etc.) discovered by Gaia, ground-based high-precision radial-velocity surveys.Comment: Accepted for publication in Experimental Astronomy. The full member list of the NEAT proposal and the news about the project are available at http://neat.obs.ujf-grenoble.fr. The final publication is available at http://www.springerlink.co

Tubulin tyrosination regulates synaptic function and is disrupted in Alzheimer's disease

: Microtubules play fundamental roles in the maintenance of neuronal processes and in synaptic function and plasticity. While dynamic microtubules are mainly composed of tyrosinated tubulin, long-lived microtubules contain detyrosinated tubulin, suggesting that the tubulin tyrosination/detyrosination cycle is a key player in the maintenance of microtubule dynamics and neuronal homeostasis, conditions which go awry in neurodegenerative diseases. In the tyrosination/detyrosination cycle, the C-terminal tyrosine of α-tubulin is removed by tubulin carboxypeptidases and re-added by tubulin tyrosine ligase. Here we show that tubulin tyrosine ligase hemizygous mice exhibit decreased tyrosinated microtubules, reduced dendritic spine density, and both synaptic plasticity and memory deficits. We further report decreased tubulin tyrosine ligase expression in sporadic and familial Alzheimer's disease, and reduced microtubule dynamics in human neurons harboring the familial APP-V717I mutation. Finally, we show that synapses visited by dynamic microtubules are more resistant to oligomeric amyloid β peptide toxicity and that expression of tubulin tyrosine ligase, by restoring microtubule entry into spines, suppresses the loss of synapses induced by amyloid β peptide. Together, our results demonstrate that a balanced tyrosination/detyrosination tubulin cycle is necessary for the maintenance of synaptic plasticity, is protective against amyloid β peptide-induced synaptic damage, and that this balance is lost in Alzheimer's disease, providing evidence that defective tubulin retyrosination may contribute to circuit dysfunction during neurodegeneration in Alzheimer's disease

Localized Surface Plasmon Resonance of Metallic Nanoparticles--Optical Property Characterization for Rational Applications

在光的激发下金属纳米结构中的自由电子能够发生群体性的振荡，进而产生表面等离激元（SPP）。发生等离激元共振时，金属纳米结构会将光束缚在表面，并在表面产生极强的电场增强。表面等离激元有两种类型：一类具有传播的特点，其表面等离激元能够在表面传播，称之为propagatingSPP；另一类不具有传播性，共振局域在一个很小的金属结构中，称之为localizedSPP，即局域表面等离激元共振（LSPR）。金属纳米颗粒就具有很强的表面等离激元共振的（LSPR）性质，使其对光产生增强的吸收和增强的散射，并表现出相关的热、光电场增强和热电子等效应。近年，随着纳米科技的发展，金属纳米粒子的LSPR效应已经成为一...The collective oscillation of free electrons in metal nanostructures excited with light is called surface plasmon polaritons (SPP). The light will be confined to a small area on the surface under the resonance condition (SPR), thus a giant enhancement in the electric field will be produced. There are two kinds of surface plasmon polaritons (SPP): one is propagating plasmon polaritons (PSPP), which...学位：理学博士院系专业：化学化工学院_物理化学(含化学物理)学号：2052010015366

De novo TBR1 variants cause a neurocognitive phenotype with ID and autistic traits:report of 25 new individuals and review of the literature

TBR1, a T-box transcription factor expressed in the cerebral cortex, regulates the expression of several candidate genes for autism spectrum disorders (ASD). Although TBR1 has been reported as a high-confidence risk gene for ASD and intellectual disability (ID) in functional and clinical reports since 2011, TBR1 has only recently been recorded as a human disease gene in the OMIM database. Currently, the neurodevelopmental disorders and structural brain anomalies associated with TBR1 variants are not well characterized. Through international data sharing, we collected data from 25 unreported individuals and compared them with data from the literature. We evaluated structural brain anomalies in seven individuals by analysis of MRI images, and compared these with anomalies observed in TBR1 mutant mice. The phenotype included ID in all individuals, associated to autistic traits in 76% of them. No recognizable facial phenotype could be identified. MRI analysis revealed a reduction of the anterior commissure and suggested new features including dysplastic hippocampus and subtle neocortical dysgenesis. This report supports the role of TBR1 in ID associated with autistic traits and suggests new structural brain malformations in humans. We hope this work will help geneticists to interpret TBR1 variants and diagnose ASD probands