Smart system model for the recruitment of teachers

Times change, for many reasons, due to technological development, new ways of doing things and in some cases forced by a global condition, is the case of the present case, where we analyze the teacher selection processes, although many of the Academic activities are developed at a distance, the selection processes also accompany this model, in this process factors that must be presented according to the profile required by the institution are analyzed, in this work a technique is proposed to be able to classify the best candidates in a Teacher selection process, the methodology consists of analyzing three groups of characteristics that the candidates must present, such as the writing exercises, the group interview and finally a demonstration class, in each of them particular criteria are evaluated, a demonstrative example It is presented as a demonstration, where it can be conditioned according to the criteria of each ins As a result, we have a computational model based on neural networks, where the best candidates can be pre-selected or classified in a teacher selection process, the prototype can be scaled and used in different sectors.Campus At

Inferior vena cava filters: a review

Venous thromboembolism is an entity that ranges from deep vein thrombosis to pulmonary embolism, both are highly prevalent diseases in our environment and potentially fatal. The intention of this review is to compile information regarding the indications, contraindications, complications and comparison of different therapeutic methods in order to create an algorithm. An exhaustive review was performed with the available literature, using the PubMed, ScienceDirect, Scopus and Cochrane databases from 2004 to 2021. The search criteria were formulated to identify reports related to inferior vena cava filters. Venous thrombosis manifested as deep vein thrombosis or pulmonary embolism is a highly prevalent disease in our setting with high morbidity and mortality. Currently, different therapeutic options have been presented to address this pathology, in this review we focus on the developments regarding the use of vena cava filters. Reviewing the indications for the placement of a vena cava filter, we find absolute indications such as a contraindication to anticoagulation and high risk of massive pulmonary embolism. Pulmonary thromboembolism is a disease with high prevalence and mortality, we have highly effective and novel treatments such as the vena cava filter, patients should be selected carefully always taking into account the absolute and relative indications

Evolving trends in the management of acute appendicitis during COVID-19 waves. The ACIE appy II study

Background: In 2020, ACIE Appy study showed that COVID-19 pandemic heavily affected the management of patients with acute appendicitis (AA) worldwide, with an increased rate of non-operative management (NOM) strategies and a trend toward open surgery due to concern of virus transmission by laparoscopy and controversial recommendations on this issue. The aim of this study was to survey again the same group of surgeons to assess if any difference in management attitudes of AA had occurred in the later stages of the outbreak. Methods: From August 15 to September 30, 2021, an online questionnaire was sent to all 709 participants of the ACIE Appy study. The questionnaire included questions on personal protective equipment (PPE), local policies and screening for SARS-CoV-2 infection, NOM, surgical approach and disease presentations in 2021. The results were compared with the results from the previous study. Results: A total of 476 answers were collected (response rate 67.1%). Screening policies were significatively improved with most patients screened regardless of symptoms (89.5% vs. 37.4%) with PCR and antigenic test as the preferred test (74.1% vs. 26.3%). More patients tested positive before surgery and commercial systems were the preferred ones to filter smoke plumes during laparoscopy. Laparoscopic appendicectomy was the first option in the treatment of AA, with a declined use of NOM. Conclusion: Management of AA has improved in the last waves of pandemic. Increased evidence regarding SARS-COV-2 infection along with a timely healthcare systems response has been translated into tailored attitudes and a better care for patients with AA worldwide

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its 'Minimal Information for Studies of Extracellular Vesicles', which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly

Robust estimation of bacterial cell count from optical density

Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data

Termite sensitivity to temperature affects global wood decay rates.

Deadwood is a large global carbon store with its store size partially determined by biotic decay. Microbial wood decay rates are known to respond to changing temperature and precipitation. Termites are also important decomposers in the tropics but are less well studied. An understanding of their climate sensitivities is needed to estimate climate change effects on wood carbon pools. Using data from 133 sites spanning six continents, we found that termite wood discovery and consumption were highly sensitive to temperature (with decay increasing >6.8 times per 10°C increase in temperature)-even more so than microbes. Termite decay effects were greatest in tropical seasonal forests, tropical savannas, and subtropical deserts. With tropicalization (i.e., warming shifts to tropical climates), termite wood decay will likely increase as termites access more of Earth's surface

Evaluation of appendicitis risk prediction models in adults with suspected appendicitis

Background Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis). Results Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent). Conclusion Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified

Protecting Women’s and Newborns’ Rights in a Public Maternity Unit During the COVID-19 Outbreak: The Case of Dra. Eloísa Díaz - La Florida Hospital in Santiago, Chile

The Maternity in Dra. Eloísa Díaz’ hospital, located in the municipality of La Florida and city of Santiago, Chile, opened its doors in 2014, and has integrated a humanistic model of care called the “Safe Model of Personalized Childbirth” since 2016. With around 3,000 births per year, it has been recognized as an example of excellence in maternity care in the country. The COVID-19 outbreak presented a big challenge to this Maternity: to maintain its quality of care standards despite the health crisis. This article presents the Maternity’s responses to the pandemic from March to July 2020, describing the strategies that were deployed and the obstetric outcomes achieved. Semi-structured interviews with midwives and OB-GYNs, and a retrospective review of the childbirth standards of care and outcomes of the 55 women who tested positive for SARS-CoV-2, were carried out. The results show how the Maternity's staff responded in order to avoid a significant negative impact on the rights of women and newborns. Protocols to reestablish the companion during labor and childbirth and skin-to-skin contact, which were suspended for almost three weeks at the beginning of the outbreak, and the creation of an Instagram account to communicate with the external community were some of the measures taken. After some initial weeks of adjustment, the standards of care for all women, included for those diagnosed with COVID-19, were reestablished almost to pre-pandemic levels. This case shows that quality of care can be maintained and the rights of women and newborns can be respected during health crisis such as the COVID-19 pandemic

Business consulting a la empresa Mibanco - Banco de la Microempresa S.A.

Mibanco, es una financiera dedicada a otorgar créditos y otros productos financieros a pequeñas y medianas empresas, por lo que se esfuerza en fortalecer la adecuada operación de sus agencias mediante la optimización de sus procesos internos para lograr una óptima atención a sus clientes actuales y potenciales. Con la finalidad de establecer un Business Consulting, se procedió a generar una análisis interno y externo de la compañía para identificar los problemas que esta pudiera tener, determinando así que hay niveles de satisfacción no logrados por parte de los procesos internos de soporte de la compañía pudiendo ocasionar así problemas en la operación a la cual soporta (agencias) en las diferentes ciudades del país. Vale decir, que al hablar de problemas internos suceden una serie de áreas, cada una con responsabilidad independiente sobre los servicios internos que brindan, por lo tuvimos que priorizar aquella cuyo puntaje de satisfacción se alejaba más de la meta, detectando los procesos de gestión de servicios. El área de gestión de servicios tiene responsabilidad en la entrega de una serie de suministros a las agencias para su adecuada operación, por lo que a través de la revisión de indicadores detectamos que no tiene un adecuado cumplimiento de SLA (niveles de servicio), sumado a los altos gastos de distribución que genera. Analizando posibles alternativas se decidió la implementación de Centros de Distribución (CD) Satélites que pudieran abastecer de manera adecuada bajo las variables de tiempo y costo a diversas agencias localizadas a nivel nacional, dejando así de depender de un solo almacén en la ciudad de Lima. Asimismo, podemos decir que la alternativa sugerida para hacer frente al problema central tiene un importante impacto buscando así reducir los altos gastos que generan los servicios de distribución, elevar los niveles de servicio por sobre la meta propuesta y obtener los puntajes definidos por Mibanco en cuando a la satisfacción del proceso por parte de los usuarios internos. Finalmente, se presenta un análisis financiero para dar mayor sustento al desarrollo e implementación de la alternativa planteada a través de la elaboración de flujos de caja proyectados para tres escenarios posibles en función a los ahorros planteados. Dichos escenarios tienes como resultado un VAN de S/893,115 y una TIR de 352%, para un escenario pesimista; un VAN de S/1,344,327 y una TIR de 512% ; para un escenario conservador; y un VAN de S/1,795,538 y una TIR de 671% , para un escenario optimista.Mibanco, is a financial company dedicated to granting loans and other financial products to small and medium-sized companies, for which it strives to strengthen the proper operation of its agencies by optimizing its internal processes to achieve optimal service for its current and potential customers. In order to establish a Business Consulting, we proceeded to generate an internal and external analysis of the company to identify the problems that it could have, thus determining that there are levels of satisfaction not achieved by the company's internal support processes. Thus, it can cause problems in the operation it supports (agencies) in the different cities of the country. That is to say, when talking about internal problems, a series of areas occur, each one with independent responsibility for the internal services they provide, so we had to prioritize the one whose satisfaction score was further from the goal, detecting the management processes of services. The service management area is responsible for the delivery of a series of supplies to the agencies for their proper operation, so through the review of indicators we detected that it does not have adequate compliance with SLAs (service levels), added to the high distribution costs it generates. Analyzing possible alternatives, it was decided to implement Satellite Distribution Centers (DCs) that could adequately supply various agencies located nationwide under the variables of time and cost, thus ceasing to depend on a single warehouse in the city of Lima. Likewise, we can say that the suggested alternative to deal with the central problem has a significant impact, thus seeking to reduce the high expenses generated by distribution services, raise service levels above the proposed goal and obtain the scores defined by Mibanco as soon as to the satisfaction of the process by internal users. Finally, a financial analysis is presented to give greater support to the development and implementation of the proposed alternative through the elaboration of projected cash flows for three possible scenarios based on the proposed savings. Said scenarios result in a NPV of S/893,115 and an IRR of 352%, for a pessimistic scenario; a NPV of S/1,344,327 and an IRR of 512%; for a conservative scenario; and a NPV of S/1,795,538 and an IRR of 671%, for an optimistic scenario