SOCIO-ECONOMIC DIMENSIONS IN LOCATIONS BY CLUSTERS IDENTIFIED FOR REGISTERED UNEMPLOYED PERSONS AT LAU2 /NUTS 5 LEVEL IN 2013 AND 2010

Identifying locations that are part of the LAU2 two types of clusters HH and LL which indicates similarities in the level of unemployment registered, with the same tendency level indicator in neighbourhood values is achieved by spatial statistical analysis method Local Indicators of Spatial Association LISA (Anselin 1995, 1996) and calculated in Geoda Software. Each location LAU2’s type (national, HH or LL) is profiled as calculated in SPSS by the statistical mean of characteristics relevant indicators to the labour market: The number of registered unemployed, number of employees, average population density / km2, average number of people entering the LAU2 following the change of domicile by reference environment and national levels in 2010 and 2013 in Romania. Data source is provided by National Institute of Statistic INS – TEMPO online database, socio-economic indicators detailed level LAU2 / NUTS 5, with a selection for 2010 and 2013. These research results have been achieved in the Project NUCLEU PN - 420 118: Spatial distribution of market indicators cohesion policy, made in 2014 and in the project DYNAHU

The regions development characterisation by diversity/variety of the firms - study case for Romania

In this paper we try to find empirical evidence regarding the region diversity by firm characteristics, using spatial data from Tempo (INS Romania database) at NUTS 1, 2 and 3 region level for the period 1997-2008. Using instruments of statistical analysis of spatial data (Anselin, Varga) we try to sketch the spatial pattern of firm agglomerations and values of main firm's characteristics (size class according to employee's number and economic activity by NACE Rev.1 sections). Starting point is represented by the discussion made by Saviotti(*) regarding the efficiency vs diversity/variety in economic development respectively development versus growth. The pattern variation of the regions "profile" by diversity/variety of the firms could offer an image for the structural transformation of economic development tendencies of it in the last decade. (*) Pier Paolo Saviotti, INRA GAEL, Grenoble, and CNRS GREDEG I2C, Sophia Antipolis, France:"Is there a direction in economic development?", Pech, 200

Bioorganically doped sol-gel materials containing amyloglucosidase activity

Amyloglucosidase (AMG) from Aspergillus niger was encapsulated in various matrices derived from tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane and vinyltriacetoxysilane by different methods of immobilization. The immobilized enzyme was prepared by entrapment in two steps, in one-step and entrapment/deposition, respectively. The activities of the immobilized AMG were assayed and compared with that of the native enzyme. The effects of the organosilaneprecursors and their molar ratios, the immobilization method, the inorganic support (white ceramic, red ceramic, purolite, alumina, TiO2, celite, zeolite) and enzyme loading upon the immobilized enzyme activity were tested. The efficiency of the sol-gel biocomposites can be improved through combination of the fundamental immobilization techniques and selection of the precursors

New Cryogels Based on Poly(vinyl alcohol) and a Copolymacrolactone System: I-Synthesis and Characterization

Physical cryogels were obtained using the successive freeze–thaw technique of poly(vinyl alcohol) (PVA)/poly(ethylene brassylate-co-squaric acid) (PEBSA) solutions. The cryogel systems were prepared by using two different molecular weights of PVA and PEBSA with three different ratios between the ethylene brassylate (EB) and squaric acid (SA) comonomers. The presence of interactions, the thermal properties and the morphology were investigated using Fourier Transform Infrared Spectroscopy (FT-IR), thermogravimetry (TGA and DTG) and scanning electron microscopy (SEM), respectively. The influence of the composition on the degree of swelling in a physiological environment was demonstrated. The study highlighted improvements in terms of new network flexibility due to the intermolecular chains interactions brought by the introduction of PEBSA in the cryogel structure. We also concluded that the presence of PEBSA in the PVA/PEBSA cryogel network improved the loading capacity of the new system with specific hydrophobic agents, for example essential oils, which (due to their antimicrobial character) can lead to the use of new systems obtained for various applications

Microcoil embolisation for ablation of septal hypertrophy in hypertrophic obstructive cardiomyopathy

Background and aim: Percutaneous transcatheter occlusion with ethanol injection of septal arteries is an efficient treatment procedure of hypertrophic obstructive cardiomyopathy (HOCM). The aim of our study was to evaluate the feasibility and efficiency of septal artery embolisation with microcoils.Methods: Microcoils were delivered through the guide-wire lumen of a 2mm-diameter coaxial balloon positioned inside the target vessel as distally as possible. One or more 0.018"-straight microcoils (Hilal straight coils, Cook, USA) were used for each target vessel until complete flow obstruction was achieved. The intraventricular pressure gradient was measured before, during and after the procedure. Septal branch occlusion was finally documented by coronary angiography.Results: We treated 7 patients (5 males; mean age: 48±10 years). All patients were symptomatic (NYHA class III or IV). The target vessels were successfully occluded in all patients without complications. Moderate pain was recorded during and after the procedure and the CK level increased five- to ten-fold. The pressure gradient diminished during the procedure from 72±21 mmHg to 30±15 mmHg. The number of coils delivered ranged from 3 to 7 per patient. The embolised septal branches included 1 vessel in 5 patients, 2 vessels in 1 patient and 3 vessels in 1 case. After the procedure, the pressure gradient, evaluated by transthoracic echocardiography, was 34±16 mmHg and 42±12 mmH at 3 month-follow-up. Clinical improvement was recorded in all patients after the procedure (NYHA class I or II). Temporary pacing was necessary in 3 patients during and immediately after the procedure but no patient needed permanent pacing.Conclusions: Microcoil embolisation is an efficient and safe approach for transcatheter ablation of septal hypertrophy in HOCM. This technique induced myocardial necrosis without the toxic effects of alcohol, reducing the risk of complications such as permanent pacemaker implantation or ethanol flow to other myocardial regions